Home Podcasts Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas

Sean Carroll 429 Episodes Jul 20, 2026

Each week, Sean Carroll hosts conversations with some of the most interesting thinkers in the world, covering topics from neuroscience and engineering to philosophy and culture. The podcast explores how music affects the brain, the nature of quantum mechanics, the workings of black holes, and the design of video games. It aims to delve into the biggest ideas in science, philosophy, culture, and more.

Episodes

361 | Bonnie Bassler on How Bacteria Talk and Work Together
361 | Bonnie Bassler on How Bacteria Talk and Work Together Jul 20, 2026 01:15:51 One of the characteristics of life is that living organisms gather information and put it to use. Even one of the simplest lifeforms, bacteria, are able to sense features of their surroundings and alter their behavior accordingly. Most impressively, they are able to sense the presence of similar bacteria by a process called quorum sensing. Today's guest, Bonnie Bassler, is a leader in this f
Mindscape Ask Me Anything, Sean Carroll | July 2026
Mindscape Ask Me Anything, Sean Carroll | July 2026 Jul 13, 2026 04:03:28 Welcome to the July 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes grou
360 | Marc Berman on the Science of Touching Grass
360 | Marc Berman on the Science of Touching Grass Jul 6, 2026 01:29:40 Modern life has, in many ways, removed us from the environments in which our ancestors lived and adapted. Not only do we spend time looking at screens, but we spend time indoors, or outdoors but in urban spaces. How does this affect how we think and feel? Psychologist Marc Berman is a pioneer of "environmental neuroscience." In his recent book, Nature and the Mind: The Science of How Nature
359 | Solo: Theories of Dark Energy
359 | Solo: Theories of Dark Energy Jun 29, 2026 01:56:11 The cosmological constant, as discussed last episode, provides a perfectly good (thus far) explanation for why we observe the universe to be accelerating. But it might not be the right explanation, and demonstrating that would be yet another foundational discovery. In this episode I discuss what is required to invent a plausible theory of dynamical dark energy, This includes considerations from pa
358 | Solo: Vacuum Energy and the Cosmological Constant
358 | Solo: Vacuum Energy and the Cosmological Constant Jun 22, 2026 01:59:50 The most surprising discovery in fundamental physics during my career as a scientist was undoubtedly the acceleration of the universe, announced in 1998. The most straightforward explanation for these observations is a positive cosmological constant, or vacuum energy. I talk about the origin of the idea with Einstein, how quantum physicists started to think about it and understand the "cosmologica
357 | Jeff Coller on mRNA, Vaccines, and Bespoke Therapeutics
357 | Jeff Coller on mRNA, Vaccines, and Bespoke Therapeutics Jun 15, 2026 01:19:51 Messenger RNA (mRNA) plays a literally central role in the functioning of life as we know it, shuttling information back and forth between the DNA where it is stored to the ribosome where it is used to produce proteins. RNA may even have been the first molecule to kick-start the origin of life. Today, scientists are learning how to manipulate mRNA to cure and prevent diseases, whether throug
356 | Andrea Wulf on Enlightenment, Nature, Romanticism, and Modernity
356 | Andrea Wulf on Enlightenment, Nature, Romanticism, and Modernity Jun 8, 2026 01:17:13 All ideas have a history, no matter how inevitable and well-entrenched they may seem to us today. The later Enlightenment was a heady time when people were exploring new conceptions of nature, humanity, and the self. Andrea Wulf is a writer of narrative histories, examining the origins of ideas through the lives of the people who explored them. In this episode we discuss three of her books: 
AMA | June 2026
AMA | June 2026 Jun 1, 2026 03:57:29 Welcome to the June 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them
355 | Solo: Looking Quantum Mechanics in the Eyeball
355 | Solo: Looking Quantum Mechanics in the Eyeball May 24, 2026 01:44:25 One of the major obstacles to understanding quantum mechanics is the difficulty we have in simply accepting what the theory itself is telling us. The problem is that we know what the everyday world looks like -- stuff, arranged in space, evolving through time. So we can't resist the temptation to impose that picture on the quantum description, even if it's not actually there. In this solo ep
354 | Christian List on Free Will and Levels of Reality
354 | Christian List on Free Will and Levels of Reality May 18, 2026 01:26:42 Did I have any freedom in choosing this particular podcast guest? At the level of particles, fields, and the fundamental laws of physics; no. At the level of human agents navigating the world, yes. Today's guest, Christian List, is a philosopher and political scientist who has arguably done the most to articulate the "compatibilist" perspective on free will, according to which the freedom of
353 | Alvin Roth on the Economics of Morally Contested Markets
353 | Alvin Roth on the Economics of Morally Contested Markets May 11, 2026 01:11:44 Economic markets are efficient ways of deciding fair prices, at least in ideal circumstances of perfect competition, information, and choice. But there is more to life than fair prices. Two people might decide on a fair price to carry out a contract killing, but society generally frowns on the idea. Many examples of morally contestable markets feature less consensus than that one: sex work,
AMA | May 2026
AMA | May 2026 May 4, 2026 04:06:12 Welcome to the May 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them

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