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Some Work, All Play

Some Work, All Play

David Roche and Megan Roche 317 Episodes Sep 15, 2026

Five to ten topics, sometimes about running, with lots of love and enthusiasm and science. The hosts dig deep into training, races, studies, pop culture, and much more. Featuring Megan Roche, M.D. and David Roche.

Episodes

328. Mysteries of Fatigue Resistance, New Science on the Lactate Shuttle, Carbs and Bone Health, and Fatigue Miles
328. Mysteries of Fatigue Resistance, New Science on the Lactate Shuttle, Carbs and Bone Health, and Fatigue Miles Sep 15, 2026 01:26:09 We had regrettable hot takes on cleaning exercise equipment before this great episode! The main training topic was on a new study highlighting the important of the lactate shuttle. We zoom out to discuss the implications for aerobic training. We also talked about mysteries around fatigue resistance! In the lab, you can’t predict fatigue resistance from fresh values (or from metabolic values during
327. How to Improve Fatigue Resistance, Weekly Mileage, Aerobic v. Anaerobic Systems, and Cycling Doses of Creatine
327. How to Improve Fatigue Resistance, Weekly Mileage, Aerobic v. Anaerobic Systems, and Cycling Doses of Creatine Sep 8, 2026 01:39:18 We had deep thoughts on thirst traps before this great episode! There were three main training topics that all fit together. First, we connected fatigue resistance to fueling and the central nervous system, using David’s long bike past his endurance limits as some evidence.Next was a new study on aerobic v. anaerobic energy contribution, finding that the 50/50 turn-point was at just 78.6 seconds.
326. HISTORY at UTMB with The Best Performance Ever (?!), Our Favorite Gel, The Future of Backyard Ultras, Heat Training in Cool Temps, and Nomio at Night!
326. HISTORY at UTMB with The Best Performance Ever (?!), Our Favorite Gel, The Future of Backyard Ultras, Heat Training in Cool Temps, and Nomio at Night! Sep 1, 2026 01:32:32 We got an extra dose of confidence before this great episode! The main topic was the history made at UTMB, with Ben Dhiman arguably running the best ultra race of all time. We also talked about being young and fit forever with Hans Troyer, the women throwing down across the board, and what we think we’re seeing with the monstrous performances at all the races.And this episode was full of fun topic
325. The Spicy Episode! Our Fears About AI Science, The $500 Trail Shoe, Age Group Doping, Zone Compression Theory, and Hog Watch
325. The Spicy Episode! Our Fears About AI Science, The $500 Trail Shoe, Age Group Doping, Zone Compression Theory, and Hog Watch Aug 25, 2026 01:28:07 We weren’t intending to have so many controversial stories this week, but here we are with some spicy topics on our hands. The main discussion was new research on Ethiopian athlete training, described as an “AI-assisted” study. The findings are cool, and we discuss those training points. But looking at the bigger picture, we have major fears about the use of AI writing across exercise physiology l
324. Why Longer Intervals May Be Worse (Sometimes), Carb Totals in Cycling, US Champ Doping, and Squats for Endurance Athletes
324. Why Longer Intervals May Be Worse (Sometimes), Carb Totals in Cycling, US Champ Doping, and Squats for Endurance Athletes Aug 18, 2026 01:27:19 We worked on our crawling economy before this great episode! The main training topic was a study on the “VO2 slow” component that may show why longer, harder intervals can actually be counterproductive for aerobic performance in some situations. At least, that’s our (biased) theory. We break it down!And this one was full of fun topics! Other topics: David’s surgery recovery, carb numbers in women’
323. The Theory of Zone Compression, Surgery (Oh No), What Comes Next, and The New Big Supplement!
323. The Theory of Zone Compression, Surgery (Oh No), What Comes Next, and The New Big Supplement! Aug 11, 2026 01:21:10 We brought some big foot energy to this great episode! The main training topic was a discussion of “zone compression,” where harder efforts get sustainable for longer durations in weird and wild ways. Our theory: zone compression techniques are driving lots of training theory. We break it all down!Before that, the episode starts with David’s news that he’s going to get surgery on his foot. We disc
322. Why Exercise Physiology Wisdom Can Be Wrong, Doping in Ultrarunning, Bicarb in Long Races, and AI Controversy!
322. Why Exercise Physiology Wisdom Can Be Wrong, Doping in Ultrarunning, Bicarb in Long Races, and AI Controversy! Aug 4, 2026 01:27:39 We excavated sand from sensitive places before this great episode! A main topic was a new study on cold water immersion, with surprising results that contrasted with the hypothesis of researchers and upended the conventional exercise physiology wisdom. We talked about why that offset might be important for how we think about big training and physiology questions. The word of the day is “nuance.” A
321. Why Hydration Unlocks Endurance, A Creatine Experiment, Tour de France Takeaways, and Athletic Identity Crisis!
321. Why Hydration Unlocks Endurance, A Creatine Experiment, Tour de France Takeaways, and Athletic Identity Crisis! Jul 28, 2026 01:36:58 We got intellectually swole on creatine and astrology before this great episode! The main science topic was a study connecting carb oxidation to hydration status. We explain how hydration is the gateway to fueling.We also provided details of the first week of David’s creatine experiment. There is some very strange heart rate data that we’re tracking. Correlation or causation? We'll find out!An
320. Why POWER Makes Champions, The Key Downhill Cue, Overnight Drug Testing at Tour de France, What We’re Trying Now, and Adult Potty Training!
320. Why POWER Makes Champions, The Key Downhill Cue, Overnight Drug Testing at Tour de France, What We’re Trying Now, and Adult Potty Training! Jul 21, 2026 01:41:26 We learned way too much about toe weightlifting before this great episode! The main topic was a discussion of a difficult, nuanced topic: how to think about power development over time, and what that means in a messy athletic life. It all comes from a “Dear Younger Me” letter that David wrote to his 11-year-old self, and it extends forward to the performance revolution we’re seeing across enduranc
319. New Fueling Lessons from The Tour de France, Uphill Treadmill Threshold Theory, Prototype Shoe Ranting, The Hardrock 100, and Coaching Questions!
319. New Fueling Lessons from The Tour de France, Uphill Treadmill Threshold Theory, Prototype Shoe Ranting, The Hardrock 100, and Coaching Questions! Jul 14, 2026 01:38:40 We spread our toes wider than nature intended before this great episode! A main topic was on the fueling evolution in the Tour de France, and how that has predicted everything that has happened across endurance sports. We also break down what fueling looked like in the 1990s from an old study! High carb is changing everything, and cycling is always the first mover on the next breakthrough.We also
318. Our Surprising Take on Carb Loading, Why Even 10 Minutes Counts, Exogenous Lactate Supplementation, and Cross Training Science!
318. Our Surprising Take on Carb Loading, Why Even 10 Minutes Counts, Exogenous Lactate Supplementation, and Cross Training Science! Jul 7, 2026 01:35:56 We campaigned for the Nobel Prize in bodily functions before this great episode! A main topic was a new review study on cross training that found no difference between cross training and running interventions FOR RUNNING PERFORMANCE. That’s wild, and we use the result to zoom out to describe why we think most athletes should be doing some cross training.We also talked about a pair of studies on ca
317. HISTORY at Western States 100! A Full Breakdown. Plus High Carb Study and Questions!
317. HISTORY at Western States 100! A Full Breakdown. Plus High Carb Study and Questions! Jun 30, 2026 01:38:16 The 2026 Western States 100 was astonishingly fast and uplifting! It was also astonishingly dramatic. This episode breaks it all down when it’s fresh in our minds.We talked the new course records and what it means to go for it in the modern era (and what it means to go for it in life). Other topics include the “death before DNF” mentality, brand battles, racing trends, and carbs in ultras. We brou

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