Lost Women of Science
For every Marie Curie or Rosalind Franklin whose story has been told, hundreds of female scientists remain unknown to the public at large. In this series, we illuminate the lives and work of a diverse array of groundbreaking scientists who, because of time, place and gender, have gone largely unrecognized. Each season we focus on a different scientist, putting her narrative into context, explaining not just the science but also the social and historical conditions in which she lived and worked. We also bring these stories to the present, painting a full picture of how her work endures.
Episodes
Tilly Edinger: The Paleoneurologist Saved By Her Science
How much can you understand about a brain when that brain is long gone? Tilly Edinger, a Jewish paleontologist, used fossilized skulls to study the evolution of brains. That research allowed her to escape Nazi Germany in 1939, and create a new subdivision of paleontology, paleoneurology.
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Kamala Sohonie: The Chemist who Wanted to Feed a Nation
In 1930s India, Kamala Baghvat dreamed of working alongside the world's greatest scientific minds. But she was repeatedly told “no” when she tried to work in the then male dominated field. Inspired by Gandhi, she used nonviolent protest to pry her way into some of India’s top laboratories. She became the first Indian woman to earn a PhD in biochemistry, and eventually, the first woman to
Sharla Boehm: The Programmer Whose Code Underpins the Internet
Sharla Boehm earned a teaching degree from UCLA before channeling her talent for math into computer programming. While working at the Rand Corporation, she built a ground-breaking simulation, originally conceived to strengthen military communications during the Cold War. The simulation –and her work– would ultimately lay the foundation for the modern internet.
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Best Of: Chemistry Professor and Crime Buster: The Remarkable Life of Mary Louisa Willard
“The only time I ever saw something that I thought was abnormal…there was a human arm in the refrigerator,” said J. Peter Willard about his aunt, Mary Louisa Willard. Otherwise, he insisted, she was “very normal.” But Mary Louisa Willard, a chemistry professor at Pennsylvania State University in the late 1920s, left a strong impression on most people, to say the least. Her hometown of Sta
Profesora de química y caza criminales: La extraordinaria vida de Mary Louisa Willard
“La única vez que vi algo que me pareció anormal… había un brazo humano en el refrigerador”, dijo J. Peter Willard sobre su tía, Mary Louisa Willard. Por lo demás, insistió, era “muy normal.” Pero Mary Louisa Willard, profesora de química en la Universidad Estatal de Pensilvania a finales de la década de 1920, dejó una fuerte impresión en la mayoría de las personas. Su ciudad natal, State
Elizabeth Roboz Einstein: The Determined Genius Behind a Multiple Sclerosis Breakthrough
Elizabeth Roboz Einstein’s life was shaped by the forces of history. She studied bioorganic chemistry at the University of Vienna in the 1920s and then left her home country of Hungary during World War II, before German troops invaded — practically a miracle for a single, Jewish woman. In the U.S., she blazed a trail in the brand new field of neurochemistry; her seminal research into mult
Conversation: If I Am Right, and I Know I Am: Inge Lehmann, the Woman Who Discovered Earth’s Innermost Secret
In this episode of Lost Women of Science Conversations, host Carol Sutton Lewis speaks with science writer Hanne Strager about her biography of Inge Lehmann, the pioneering Danish seismologist who discovered that Earth has a solid inner core.. Largely unknown outside scientific circles, Lehmann fundamentally transformed our understanding of what lies at the heart of our planet. She did th
BONUS: Agnes Pockels and the Kitchen Sink Myth
This bonus episode is a co-production with Distillations, a podcast produced by the Science History Institute.Agnes Pockels did pioneering work in surface science. Her invention, the Pockels Trough, became the basis for an instrument that helped Katherine Burr Blodgett and Irving Langmuir make discoveries in material science that quietly shape our everyday world. But the way we talk about
Layers of Brilliance: Vanishing Act -- Episode Six
How is a legacy preserved, and how is someone forgotten? Determined to make a final name for himself, Irving Langmuir ventures into science that even he might classify as pathological wishful thinking, while Katharine continues her work as the diligent experimenter. But her contributions faded from both the company’s and the public’s memory. We go to visit her, to say good-bye – and we lo
Layers of Brilliance: The Self You Have to Live With - Episode Five
Katharine’s relatives lead the production team to a collection of papers and artifacts stored in a New England storage unit, revealing an inner struggle she kept carefully out of sight – even as she was making history in the laboratory.
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Layers of Brilliance: The Breakthrough - Episode Four
The 1930s prove to be an exceptional decade for research at The General Electric Company. Katharine Burr Blodgett works closely alongside her boss, Irving Langmuir who, in 1932, wins the Nobel Prize for Chemistry. In 1938, Katharine’s meticulous experiments with thin film coatings on solid surfaces lead to her most important breakthrough: non-reflecting glass. The General Electric Company
Layers of Brilliance: The Air She Breathed -- Episode Three
The only woman in a laboratory filled with men, Katharine Burr Blodgett soon becomes indispensable as an assistant to The General Electric Company’s most famous scientist, Irving Langmuir. Their working relationship is an elegant symbiosis: her forte is experimentation, his is scientific theory. We follow their partnership as they successfully find ways to build a better lightbulb but Lan
Layers of Brilliance: The 'House of Magic' -- Episode Two
Katharine Burr Blodgett arrives at The General Electric Company’s legendary research laboratory in Schenectady, New York, known as the “House of Magic.” She was just 20 years old when she entered a world built almost entirely for men. She joins as assistant to the brilliant and eccentric Irving Langmuir, a star chemist whose fundamental work in materials science and light bulbs would brin
Layers of Brilliance: The Chemical Genius of Katharine Burr Blodgett - Episode One
In the first of this five-part season we trace Katharine’s early years as she picks up European languages, her early scientific education at a progressive New York school for girls and then Bryn Mawr, a women’s college. She seems destined to end up working at the General Electric Company’s industrial research lab, but first she must prove herself at the University of Chicago, where, in th
Layers of Brilliance
Introducing Layers of Brilliance, a six-part season that brings to life the story of a woman whose discoveries in materials science quietly shape our everyday world – but whose legacy was long eclipsed by the famous scientist she worked with.In 1918, at just twenty years old, Katharine Burr Blodgett arrived at the General Electric Company’s industrial research laboratory in Schenectady, N
The Lost Women of Science - Our Book for Young Readers
The Lost Women of Science by Melina Gerosa Bellows and Katie Hafner is an exciting book for young readers that brings to life the stories of ten remarkable women who changed the world of science but have been forgotten, or written out of history completely. Published by Penguin Random House’s Bright Matter imprint, the book transforms podcast episodes into a collection of inspiring biogra
For Susan
In 2022, Susan Wojcicki was on top of the world—CEO of YouTube, parent to five kids, and running a few miles a day—when she received a shocking diagnosis: metastatic lung cancer. She soon resigned from YouTube and dedicated herself to fighting the disease and looking for answers. Why does the leading cause of cancer deaths receive less funding than some less lethal cancers? How could her
The Mouse Lady
In the 1910s, a relatively unknown cancer researcher named Maud Slye announced the first results of a study with the loftiest ambitions: to identify what causes cancer. To answer that question, the University of Chicago geneticist had bred tens of thousands of mice, enough to fill a three-story building. She carefully documented their ancestry and their morbidities and performed autopsies
Lost Women of Science Conversations: Rosalind - The Opera
Composer Peter Hugh White and librettist Clare Heath join host Rosie Millard in front of a London audience to explore why the story of chemist and x-ray crystallographer Rosalind Franklin and the race to uncover the structure of DNA makes such a compelling subject for an opera.We hear excerpts that capture the contrasting personalities at the centre of this scientific drama — James Watson
Best Of: Finding Dora Richardson: The Forgotten Developer of Tamoxifen, a Lifesaving Breast Cancer Therapy - Episode Two
Although initial clinical trials of tamoxifen as a treatment of breast cancer were positive, Imperial Chemical Industries (ICI) did not believe this market would be commercially viable. The company had hoped for a contraceptive pill – tamoxifen didn’t work for that – not a cancer treatment. In 1972 the higher-ups at ICI decided to cancel the research.But Dora Richardson, the chemist who
Encontrando a Dora Richardson – La desarrolladora olvidada del tamoxifeno, una terapia vital contra el cáncer de mama
Aunque los ensayos clínicos iniciales del tamoxifeno como tratamiento del cáncer de mama fueron positivos, Imperial Chemical Industries (ICI) no creía que este mercado fuera comercialmente viable. La compañía esperaba una píldora anticonceptiva (el tamoxifeno no funcionó para eso), no un tratamiento contra el cáncer. En 1972, los superiores del ICI decidieron cancelar la investigación.
Best Of: Finding Dora Richardson, The Forgotten Developer of Tamoxifen, a Lifesaving Breast Cancer Therapy - Episode One
In the early 1960s, Dr. Dora Richardson synthesized a chemical compound that became one of the most important drugs to treat breast cancer: tamoxifen. Although her name is on the original patent, her contributions have been lost to history.In the first episode of this two-part podcast, Katie Couric introduces us to Dora’s story, and we show how Lost Women of Science producer Marcy Thompso
Encontrando a Dora Richardson – Episodio 1
A principios de la década de los sesenta, la Dra. Dora Richardson sintetizó un compuesto químico que se convirtió en uno de los medicamentos más importantes para tratar el cáncer de mama: el tamoxifeno. Aunque su nombre aparece en la patente original, sus contribuciones fueron olvidadas por la historia. En el primer episodio de este podcast de dos partes, les contamos la historia de Dora
Opening Doors to Computer Science
In high school, Carla Brodley was almost shut out of computer science when boys took over all the computers. But she rediscovered her love for the field in college and has made it her mission to open doors for others. At Northeastern University, she founded the Center for Inclusive Computing, which now partners with more than 100 institutions to make computer science more accessible. As a
Frances Glessner Lee: The Mother of Forensic Science
Frances Glessner Lee discovered her true calling later in life. An heiress without formal schooling, she was in her fifties when she transformed her fascination with true crime and medicine into the foundation of a new field: forensic science. In the late 1920s, she drew inspiration from a family friend, a medical examiner involved in notorious cases— including the infamous Sacco and Vanz
The Mothers of Gynecology
In this episode, Katie Hafner joins Alexis Pedrick and Mariel Carr to bring you The Mothers of Gynecology, part of Innate: How Science Invented the Myth of Race, a podcast and magazine project produced by the Science History Institute that explores the historical roots and persistent legacies of racism in American science and medicine.Of all wealthy countries, the United States is the mos
Best Of: Dr. Sarah Loguen Fraser, an Ex-Slave’s Daughter, Becomes a Celebrated Doctor
Born in 1850, Sarah Loguen found her calling as a child, when she helped her parents and Harriet Tubman bandage the leg of an injured person escaping slavery. When the Civil War ended and Reconstruction opened up opportunities for African Americans, Loguen became one of the first Black women to earn a medical license. But quickly, racist Jim Crow laws prevailed. At the urging of family fr
La Dra. Sarah Loguen Fraser, hija de un ex esclavo, se convierte en una destacada médica
Nacida en 1850, Sarah Loguen encontró su vocación cuando era niña, cuando ayudó a sus padres y a Harriet Tubman a vendar la pierna de una persona herida que escapaba de la esclavitud. Cuando terminó la Guerra Civil y la Reconstrucción abrió oportunidades para los afroamericanos, Loguen se convirtió en una de las primeras mujeres negras en obtener una licencia médica. Pero rápidamente, pre
Mujeres perdidas del Proyecto Manhattan: Carolyn Beatrice Parker
Carolyn Beatrice Parker provenía de una familia de médicos y académicos y trabajó durante la Segunda Guerra Mundial como física en el Proyecto Dayton, una parte fundamental del Proyecto Manhattan encargada de producir polonio. El polonio es un metal radiactivo que se utilizó en la producción de las primeras armas nucleares. Después de la guerra, Parker continuó su investigación y sus estu
Best Of: Lost Women of the Manhattan Project - Carolyn Beatrice Parker
Carolyn Beatrice Parker came from a family of doctors and academics and worked during World War II as a physicist on the Dayton Project, a critical part of the Manhattan Project tasked with producing polonium. Polonium is a radioactive metal that was used in the production of early nuclear weapons. After the war, Parker continued her research and her studies at the Massachusetts Institute
Emma Unson Rotor: la física filipina que desarrolló un arma ultrasecreta
Emma Unson Rotor se tomó un permiso de su trabajo como profesora de matemáticas en Filipinas para estudiar física en la Universidad Johns Hopkins en 1941. Sus planes se vieron interrumpidos cuando el Ejército Imperial Japonés invadió y ocupó Filipinas. Incapaz de acceder a la beca que le había brindado el gobierno filipino para asistir a Johns Hopkins, se unió a la División de Desarrollo
Best Of: Emma Unson Rotor: The Filipina Physicist Who Developed a Top Secret Weapon
Emma Unson Rotor took leave from her job as a math teacher in the Philippines to study physics at Johns Hopkins University in 1941. Her plans were disrupted when the Imperial Japanese Army invaded and occupied the Philippines. Unable to access her Philippine government scholarship to attend Johns Hopkins, she joined the Ordnance Development Division at the National Bureau of Standards. It
Best Of: The Victorian Woman Who Chased Eclipses
The year is 1897 and Annie Maunder, an amateur astronomer, is boarding a steamship bound for India from England. Her goal: to photograph a total solar eclipse. Maunder was fascinated by the secrets of the sun and was determined to travel the globe and unlock them. She understood that the few minutes of darkness during a solar eclipse presented a special opportunity to explore the nature o
La mujer victoriana que perseguía los eclipses
Corre el año 1897 y Annie Maunder, una astrónoma aficionada, aborda un barco de vapor con destino a la India desde Inglaterra. Su objetivo: fotografiar un eclipse total de sol. Maunder estaba fascinado por los secretos del sol y estaba decidido a viajar por el mundo y descubrirlos. Comprendió que los pocos minutos de oscuridad durante un eclipse solar presentaban una oportunidad especial
Lost Women of Science - Mujeres Olvidadas de la Ciencia - En Espanõl
Esto es Lost Women of Science - Mujeres Olvidadas de la Ciencia. Laura Gómez, conocida por su papel de Blanca Flores en la exitosa serie de Netflix “Orange Is the New Black”, es el narradora del podcast Lost Women of Science en el que contamos las historias de destacadas científicas cuyo trabajo cambió nuestro mundo, pero cuyos nombres fueron prácticamente olvidados y casi borrados de la
Lost Women of Science - In Spanish!
After the success of our bilingual season about the first female doctor trained in the Dominican Republic, The Extraordinary Life and Tragic Death of Evangelina Rodríguez Perozo, we are adapting more of our episodes in Spanish. Starting next week, listen out for the stories of astronomer Annie Maunder, physicists Emma Unson Rotor and Carolyn Parker, and chemist and forensic scientist Mary
The Weather Expert Who Answered the $64,000 Question
In the mid-1940s, a teenage June Bacon-Bercey saw the image of a nuclear explosion on the cover of Time magazine and immediately had questions. How would the particles in the mushroom cloud move through the air? What effect would this have on our atmosphere? To find the answers, she set out to study atmospheric science, just as the field of meteorology was coming of age.Her career would t
Florence Nightingale and her Geeks Declare War on Death
In this episode from the Cautionary Tales podcast, Harford teams up with actor Helena Bonham Carter, a distant relative of Florence Nightingale, to tell the story of how the ‘“Lady with the Lamp” revolutionized public health with a pie chart. Nightingale was a statistician as well as a nurse, and it was her use of data graphics that led hospitals to introduce hygiene measures that we now
Lost Women of Science Conversations: Air-borne
Air-Borne: the Hidden History of the Air We Breathe by Carl Zimmer charts the history of the field of aerobiology: the science dealing with airborne microorganisms. In this episode, we discover the story of two lost pioneers of the 1930s, physician and self-taught epidemiologist Mildred Weeks Wells and her husband sanitary engineer William Firth Wells, who proved that infectious disease
Buried History: The Feminist Birth of the Home Pregnancy Test
Today, we take it for granted that you can buy a home pregnancy test at the pharmacy. Before the end of the 1970s, this was not the case. Then along came Margaret Crane, a young designer working for a pharmaceutical company. Looking at the rows of pregnancy tests in the lab one day in 1965, she thought, “Well, women could do that at home!” But Crane faced an uphill battle to convince the
Lost Women of Science Conversations: The Elements of Marie Curie
In The Elements of Marie Curie: How the Glow of Radium Lit a Path for Women in Science Dava Sobel celebrates the many women who came to Paris to work with Marie Curie after she won the 1903 Nobel Prize in Physics. Many of these women went on to become experts in radioactivity, creating their own networks to support female scientists. Among others, we meet Norwegian Ellen Gleditsch, who wa
In Evangelina's Footsteps | 5
After Evangelina Rodríguez Perozo died in 1947, the Trujillo regime did its best to erase her legacy, while at the same time appropriating her ideas. Yet those who had known and loved Evangelina in San Pedro de Macorís, where she spent most of her life, kept her memory alive, sharing stories of her kindness and her work. After the assassination of Rafael Leónidas Trujillo in 1961, Dominic
Siguiendo los pasos de Evangelina | 5
Tras la muerte de Evangelina Rodríguez Perozo en 1947, el régimen de Trujillo hizo todo lo posible no solo por borrar su legado, sino también por apropiarse de sus ideas. Sin embargo, quienes conocieron y quisieron a Evangelina en San Pedro de Macorís mantuvieron su memoria viva, compartiendo historias sobre su bondad y su trabajo. Tras el asesinato de Rafael Leónidas Trujillo en 1961, lo
El dictador y la doctora | 4
En 1930, Rafael Leónidas Trujillo toma el poder en la República Dominicana e instaura un reino de terror. El controvertido trabajo de Evangelina la puso en conflicto con el nuevo régimen. Sus ideas radicales sobre la sanidad y los derechos de la mujer, junto con su negativa a doblegarse ante Trujillo, la dejaron cada vez más aislada. Cada vez más gente se distanciaba de ella. Con los años
The Dictator and the Doctor | 4
In 1930, Rafael Leónidas Trujillo seized power in the Dominican Republic and introduced a reign of terror. Evangelina’s controversial work brought her into conflict with the new regime. Her radical ideas about healthcare and women's rights, along with her refusal to kowtow to Trujillo, left her increasingly isolated. More and more people distanced themselves from her. Over the years, her
El retorno de la doctora rebelde | 3
Evangelina recibió una calurosa bienvenida de regreso a su país, y se pone a trabajar de inmediato, introduciendo sus nuevas ideas sobre la atención en salud a mujeres y niños. Montó su propio consultorio médico, y convenció a algunos campesinos para que distribuyesen leche gratis a niños pobres. Pero su proselitismo alrededor de los métodos anticonceptivos y su trabajo con prostitutas in
The Rebel Doctor Returns | 3
Evangelina got a warm welcome on her return from Paris and went straight to work, introducing her new ideas about healthcare for women and children. She set up a new medical practice, and managed to get farmers to provide free milk for poor infants. But her proselytizing about contraception and her work with prostitutes made even her friends uncomfortable. Her ideas were ahead of her time
A Dominican in Paris | 2
Devastated by the death of her mentor following childbirth, Evangelina decided to devote her life to women’s health. It took a decade to raise the money to go to Paris, which was then the mecca of medical training, but she never gave up. At the age of 42 she boarded a steamship to France. Amidst the post-war scene of France's Roaring Twenties, she studied obstetrics and gynecology with le
Una dominicana en París | 2
Devastada por la muerte de su mentora, ocurrida tras un parto, Evangelina decidió dedicar su vida a la salud de la mujer. Tardó una década en reunir el dinero para ir a París, que en ese entonces era la meca de la formación médica. Nunca se rindió. A los 42 años se embarcó en un buque de vapor rumbo a Francia, país que experimentaba un boom durante los años de la posguerra. Estudió obstet
La doctora | 1
A finales de la década de 1890, Andrea Evangelina Rodríguez Perozo era una de las tantas niñas pobres luchando por sobrevivir en la ciudad de San Pedro de Macorís, en la República Dominicana. Su vida dio un giro extraordinario cuando dos hermanos, poetas y escritores, llegaron de la capital. Notaron algo especial en la joven, quien vivía cerca. Con su ayuda, Evangelina fue a la escuela y,
La Doctora | 1
In the late 1890s, Andrea Evangelina Rodríguez Perozo, known as Evangelina, was just another poor girl trying to survive in the provincial town of San Pedro de Macorís in the Dominican Republic. Her life took an extraordinary turn when two brothers, both poets and writers, arrived from the capital. They noticed something special about the young girl who lived nearby. With their help, Evan
La Extraordinaria Vida y Trágica Muerte de Evangelina Rodríguez Perozo
En la década de 1880, una pequeña niña Afro-Dominicana pasaba sus días vendiendo dulces en las calles de San Pedro de Macorís, una bulliciosa ciudad portuaria en la República Dominicana. Abandonada por sus padres, quienes la tuvieron por fuera del matrimonio, su futuro parecía gris: en esta sociedad profundamente estratificada, pocas personas lograban escapar de la vida en la que habían n
The Extraordinary Life and Tragic Death of Evangelina Rodríguez Perozo
In the 1880s, a small Afro-Dominican girl spent her days selling sweets on the streets of San Pedro de Macorís, a bustling port town in the Dominican Republic. Born out of wedlock and abandoned by her parents, her horizons seemed narrow — in this deeply stratified society, few people ever broke free from the life they were born into.But Andrea Evangelina Rodríguez Perozo had something tha
Lost Women of Science Conversations: Lady Tan's Circle of Women
Lisa See’s novel Lady Tan’s Circle of Women is inspired by a medical textbook published in 1511 by an eminent female doctor, Tan Yunxian. In this episode, we talk to See about the origin of her novel, and to Lorraine Wilcox, the scholar who translated the original Chinese text, about what the practice of medicine was like for a female doctor during the Ming Dynasty. Tan Yunxian was almos
Who Discovered the Cause of Down Syndrome ? Episode Two
In 1960 Marthe Gautier left the lab where she had discovered the genetic cause of Down syndrome, and went on to have a successful career as a pediatric cardiologist. For decades, she remained silent as her former colleague Jérôme Lejeune continued to take credit for this pioneering discovery, and history wrote her out of the story. Until 2009. On the 50th anniversary of the paper that ann
Who Discovered the Cause of Down Syndrome? Episode One
In the mid-1950s Marthe Gautier, a young French doctor and cytogenetics researcher, led a cutting-edge experiment to investigate the cause of Down syndrome. She painstakingly cultured cells in a ramshackle lab until one day she discovered an extra chromosome in the cells of patients with Down syndrome. This proved beyond a doubt that Down syndrome is genetic.In this first episode of our t
Margarethe Hilferding, Sigmund Freud, and the Conspiracy of Silence
In honor of International Holocaust Remembrance Day, we are telling the story of Margarethe Hilferding, a pioneering psychoanalyst and physician from Vienna who was murdered in a Nazi concentration camp in 1942. She was the first woman to earn a medical degree at the University of Vienna and the first woman to join Sigmund Freud’s Vienna Psychoanalytic Society. In her paper On the Basis o
Lost Women of Science Conversations: Breaking Through
Dr. Katalin Karikó, a Hungarian-born biochemist, dedicated her life’s work to messenger RNA, which she always believed had the potential to change the world. After decades of being ignored, she persisted with the research that eventually revolutionized the field of medicine and enabled the development of lifesaving vaccines in record time during the COVID-19 pandemic. Dr. Karikó tells her
Best Of: Flora Patterson, the Woman who Kept Devastating Blights from U.S. Shores
At this festive time of year, when many people are bringing trees into their homes to decorate for the holidays, we are going back to our story of a pioneering scientist who made it her mission to ensure that plants traveling across borders did not carry any diseases. It was in 1909, that the Mayor of Tokyo sent a gift of 2,000 prized cherry trees to Washington, D.C. But the iconic blosso
Lost Women of Science Conversations - Brave the Wild River
Two female botanists – Elzada Clover and Lois Jotter – made headlines for riding the rapids of the Colorado River in 1938 in an effort to document the Grand Canyon’s plant life. In Brave the Wild River: The Untold Story of Two Women Who Mapped the Botany of the Grand Canyon, author Melissa L. Sevigny retraces their journey and shows how the ambitious river expedition, one that many believ
Lost Women of the Manhattan Project: Carolyn Beatrice Parker
Carolyn Beatrice Parker came from a family of doctors and academics and worked during World War II as a physicist on the Dayton Project, a critical part of the Manhattan Project tasked with producing polonium. (Polonium is a radioactive metal that was used in the production of early nuclear weapons.) After the war, Parker continued her research and her studies at the Massachusetts Institu
Lost Women of Science Conversations: Attention is Discovery
Anna Von Mertens' thoughtful new exploration of Henrietta Swan Leavitt's life describes and illuminates Leavitt's decades-long study of stars, including the groundbreaking system she developed for measuring vast distances within our universe simply by looking at photographic plates. Leavitt studied hundreds of thousands of stars captured on the glass plates at the Harvard College Observat
Finding Dora Richardson: The Forgotten Developer of Tamoxifen, a Lifesaving Breast Cancer Therapy - Episode Two
Although initial clinical trials of tamoxifen as a treatment of breast cancer were positive, Imperial Chemical Industries (ICI) did not believe this market would be commercially viable. The company had hoped for a contraceptive pill – tamoxifen didn’t work for that – not a cancer treatment. In 1972 the higher-ups at ICI decided to cancel the research. But Dora Richardson, the chemist who
Finding Dora Richardson - The Forgotten Developer of Tamoxifen
In the early 1960s, chemist Dr. Dora Richardson synthesized a chemical compound that became one of the most important drugs to treat breast cancer: tamoxifen. Although her name is on the original patent, her contributions have been lost to history. In the first episode of this two-part podcast, Katie Couric introduces us to Dora’s story. Lost Women of Science producer Marcy Thompson track
Lost Women of Science Conversations: Wonder Drug
While researching her book about thalidomide in America, Jennifer Vanderbes discovered that there were far more survivors in the U.S. than originally thought – at least ten times more. These survivors were born with shortened limbs and other serious medical conditions after their mothers unwittingly took thalidomide in the early 1960s in so-called clinical trials. Wonder Drug tells the st
The Devil in the Details - Chapter Five
It’s September 2024 and a group of American thalidomide survivors arrive in Washington D.C. to lobby the government for support. More than 60 years have gone by since Frances Kelsey first stalled the New Drug Approval application from pharma company Merrell for thalidomide. Although she stopped the drug from going on the market in the U.S., hundreds of pregnant women still took thalidomid
The Devil in the Details - Chapter Four
It’s the summer of 1962 and thalidomide has been off the market in Europe for months. But in the U.S., people are only just beginning to find out about the scandal. The Washington Post breaks the story and puts a picture of Frances Kelsey on the front page. She’s the hero who saved American lives. President John F. Kennedy gives her a medal and her image is splashed across newspapers arou
The Devil in the Details - Chapter Three
It’s 1961 and Widukind Lenz, a German pediatrician, is going door to door in his efforts to find out what is causing the epidemic of babies born with shortened limbs and other serious medical conditions. In the U.S., drug company Merrell is battling with Dr. Frances Kelsey at the Food and Drug Administration about the approval for thalidomide. She’s asking for data that shows it’s safe in
The Devil in the Details - Chapter Two
It’s the early 1960s and the German pharmaceutical market is booming. A sedative called Contergan is one of the bestselling drugs. Contergan’s active ingredient is thalidomide and it is touted as a wonder drug, a non-addictive sedative safer than barbiturates. In the U.S., the drug is called Kevadon, and its distributor is impatient to get the drug on the market. But Dr. Frances Kelsey, a
The Devil in the Details - Chapter One
In this first chapter of a new five-part season we meet Dr. Frances Oldham Kelsey, a physician and pharmacologist who joined the U.S. Food and Drug Administration as a medical reviewer in 1960. Before the year is out, Dr. Kelsey finds herself standing up to big pharma. It’s September 1960 and a thick New Drug Application lands on Dr. Kelsey’s desk. The drug has already been on the market
Trailer: The Devil in the Details
In the 1950s, a German drug company developed a new sedative that was supposed to be 100% safe: thalidomide. So safe, in fact, it was promoted to women as a treatment for morning sickness. It quickly became a bestseller. But in the early 1960s, shocking news started coming out of Europe. Thousands of babies were being born with shortened arms and legs, heart defects, and other serious pro
Lost Women of Science Conversations: Writing for Their Lives
In the 1920s, when newspapers and magazines started to showcase stories about science, many of the early science journalists were women, working alongside their male colleagues despite less pay and outright misogyny. They were often single or divorced and, as Marcel Chotkowski LaFollette explains, writing for their lives. From Emma Reh, who traveled to Mexico to get a divorce and ended up
The Quest for Everything
By the second half of the 20th century, physicists were on a mission to find the ultimate building blocks of the universe. What you get when you zoom in all the way to the tiniest bits that can’t be broken down anymore. They had a kind of treasure map, a theory describing these building blocks and where we might find them. But to actually find them, physicists needed to recreate the blist
Dr. Jess Wade, Physicist and Wikipedia Maven
Dr. Jess Wade is a physicist at Imperial College London who’s made it her mission to write and update the Wikipedia pages of as many women in STEM as she possibly can. She inspired us at Lost Women of Science to start our own Wikipedia project to ensure that all the female scientists we profile have accurate and complete Wikipedia pages. In this episode, Jess talks with us about what she
Lost Women of Science Conversations: The Exceptions
Dr. Nancy Hopkins, a molecular biologist who made major discoveries in cancer genetics, became an unlikely activist in her early fifties. She had always believed that if you did great science, you would get the recognition you deserved. But after years of humiliations — being snubbed for promotions and realizing the women's labs were smaller than those of their male counterparts — she fin
Chemistry Professor and Crime Buster: The Remarkable Life of Mary Louisa Willard
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When Laura J. Martin decided to write a history of ecological restoration, she didn’t think she would have to go back further than the 1980s to uncover its beginnings. What she found, however, deep in the archives, was evidence of a network of early female botanists from the turn of the last century who had been written out of history. Wild by Design: The Rise of Ecological Restoration se
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