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Dwarkesh Podcast

Dwarkesh Podcast

Dwarkesh Patel 127 episodes Latest May 22, 2026

Deeply researched interviews with experts on a variety of topics, hosted by Dwarkesh Patel. The podcast explores ideas in technology, science, philosophy, and more. Each episode features in-depth conversations that aim to uncover insights and understanding.

Episodes

Alex Imas and Phil Trammell – What remains scarce after AGI? Jun 4, 2026 4568 Economics of AGI episode w Alex Imas and Phil Trammell.There’s a bunch of important questions about how we deal with AI that only economics can answer.What is the optimal way to tax and redistribute the wealth that will be generated? How should countries not in the AI supply chain index into the gains? Is there any world where inequality doesn’t explode?It might seem like these questions have obvi
Reiner Pope – Chip design from the bottom up May 22, 2026 4830 New blackboard lecture with Reiner Pope: how do chips actually work - starting with basic logic gates, and working up to why GPUs, TPUs, FPGAs, and the human brain each look the way they do.Reiner is CEO of MatX, a new chip startup (full disclosure - I’m an angel investor). He was previously at Google, where he worked on software efficiency, compilers, and TPU architecture.Watch this one on YouTub
Eric Jang – Building AlphaGo from scratch May 15, 2026 9449 Eric Jang walks through how to build AlphaGo from scratch, but with modern AI tools.Sometimes you understand the future better by stepping backward. AlphaGo is still the cleanest worked example of the primitives of intelligence: search, learning from experience, and self-play. You have to go back to 2017 to get insight into how the more general AIs of the future might learn.Once he explained how A
David Reich – Why the Bronze Age was an inflection point in human evolution May 8, 2026 8000 David Reich is back.He and collaborator Ali Akbari just published a paper that overturns a long-standing consensus about human evolution — that natural selection has been dormant in our species since the agricultural revolution.By scaling ancient DNA sequencing and developing a new statistical method, they found that selection has actually sped up.Selection went especially bonkers during the Bronz
Reiner Pope – The math behind how LLMs are trained and served Apr 29, 2026 8030 Did a very different format with Reiner Pope - a blackboard lecture where he walks through how frontier LLMs are trained and served.It’s shocking how much you can deduce about what the labs are doing from a handful of equations, public API prices, and some chalk.It’s a bit technical, but I encourage you to hang in there – it’s really worth it.There are less than a handful of people who understand
Jensen Huang – TPU competition, why we should sell chips to China, & Nvidia’s supply chain moat Apr 15, 2026 6192 I asked Jensen about TPU competition, Nvidia’s lock on the ever more bottlenecked supply chain needed to make advanced chips, whether we should be selling AI chips to China, why Nvidia doesn’t just become a hyperscaler, how it makes its investments, and much more. Enjoy!Watch on YouTube; read the transcript.Sponsors* Crusoe’s cloud runs on state-of-the-art Blackwell GPUs, with Vera Rubin deploymen
Michael Nielsen – How science actually progresses Apr 7, 2026 7383 Really enjoyed chatting with Michael Nielsen about how we recognize scientific progress.It's especially relevant for closing the RL verification loop for scientific discovery.But it's also a surprisingly mysterious and elusive question when you look at the history of human science.We approach this question stories like Einstein (who claimed that he hadn't even heard of the famous Michelson-Morley
Terence Tao – Kepler, Newton, and the true nature of mathematical discovery Mar 20, 2026 5024 We begin the episode with the absolutely ingenious and surprising way in which Kepler discovered the laws of planetary motion.People sometimes say that AI will make especially fast progress at scientific discovery because of tight verification loops.But the story of how we discovered the shape of our solar system shows how the verification loop for correct ideas can be decades (or even millennia)
Dylan Patel — Deep dive on the 3 big bottlenecks to scaling AI compute Mar 13, 2026 9044 Dylan Patel, founder of SemiAnalysis, provides a deep dive into the 3 big bottlenecks to scaling AI compute: logic, memory, and power.And walks through the economics of labs, hyperscalers, foundries, and fab equipment manufacturers.Learned a ton about every single level of the stack. Enjoy!Watch on YouTube; read the transcript.Sponsors* Mercury has already saved me a bunch of time this tax season.
The most important question nobody's asking about AI Mar 11, 2026 1478 Read the full essay here: https://www.dwarkesh.com/p/dow-anthropicTimestamps(00:00:00) - Anthropic vs The Pentagon(00:04:16) - The overhangs of tyranny(00:05:54) - AI structurally favors mass surveillance(00:08:25) - Alignment...to whom?(00:13:55) - Coordination not worth the costs Get full access to Dwarkesh Podcast at www.dwarkesh.com/subscribe
Why Leonardo was a saboteur, Gutenberg went broke, and Florence was weird – Ada Palmer Mar 6, 2026 7339 Renaissance history is so much wilder and weirder than you would have expected. Very fun chatting with Ada Palmer (historian, novelist, and composer based at the University of Chicago).Some especially fascinating things I learned from the conversation and her excellent book, Inventing the Renaissance:Not only did Gutenberg go bankrupt in the 1450s (after inventing the printing press), but so did t
Dario Amodei — "We are near the end of the exponential" Feb 13, 2026 8540 Dario Amodei thinks we are just a few years away from AGI — or as he puts it, from having “a country of geniuses in a data center”. In this episode, we discuss what to make of the scaling hypothesis in the current RL regime, why task-specific RL might lead to generalization, and how AI will diffuse throughout the economy. We also dive into Anthropic’s revenue projections, compute commitments, path

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