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Sigma Nutrition Radio

Sigma Nutrition Radio

Danny Lennon 629 episodes Latest Jun 2, 2026

Discussions about the science of nutrition, dietetics and health. The podcast that educates through nuanced conversations, exploring evidence and cultivating critical thinking. Hosted by Danny Lennon.

Episodes

#609: Unprocessed Red Meat & Cancer Risk Jun 9, 2026 01:09:44 Unprocessed red meat and cancer risk remains one of the most debated topics in nutrition science, partly because the evidence is often presented in overly simplistic terms. The key question is not whether to adopt a vague "balanced" position on red meat, but whether the evidence clearly identifies intake levels at which colorectal cancer risk increases and whether controlled human trials support p
#608: Performance Nutrition in Elite Rugby – James Morehen, PhD Jun 2, 2026 01:08:02 Performance nutrition in elite sport is often discussed in terms of meal plans, supplements, and macronutrient targets. However, effective practice in professional environments depends just as much on education, trust, communication, and the ability to translate scientific principles into decisions athletes can act on under real-world constraints. In this episode, Dr James Morehen discusses his wo
#607: Gut Health & Microbiome Testing: What Evidence Do We Actually Have? – Emily Leeming, PhD May 26, 2026 50:41 Gut health has become a major focus in nutrition, medicine, and consumer wellness, but the term is often used loosely. Claims about microbiome testing, probiotics, fermented foods, fibre, and "boosting" the gut microbiome are now common, yet the evidence behind these claims varies substantially. In this episode, Dr. Emily Leeming examines what gut health actually refers to, why it cannot be reduce
PMOS (PCOS) and Diet: What Can Nutrition Realistically Do? - SNP#50 May 21, 2026 19:13 In this episode, we examine what nutrition can realistically do in the condition historically known as PCOS, now renamed polyendocrine metabolic ovarian syndrome, or PMOS. We begin by explaining why the name change matters: the condition is not defined by ovarian cysts, but is better understood as a broader endocrine-metabolic and ovarian syndrome involving insulin resistance, androgen excess, ovu
#606: Practical Nutrition Strategies for Fat Loss – Luke Hanna May 19, 2026 41:23 Body composition goals, particularly bodyfat loss, are among the most common reasons people seek support from a nutritionist or health and fitness professional. While the principles are well established, the challenge is helping individuals apply them consistently in real-world conditions. Many people struggle due to hunger, unrealistic expectations, emotional eating, inconsistent routines, or ove
#605: Fasting, Nutrient Timing & CGMs: Interpreting the Evidence – Prof. James Betts May 12, 2026 56:13 Fasting, nutrient timing, chrono-nutrition, and continuous glucose monitoring are all topics that have generated substantial interest, but they are also areas where exaggerated claims can easily outpace the underlying evidence. In many cases, tentative hypotheses are presented as if they were already well-established conclusions, despite the fact that the research base is often more mixed and cont
#604: How To Interpret Nutrition Research – David Allison, PhD May 5, 2026 52:16 How should we decide what counts as trustworthy evidence? Scientific rigor is not a single characteristic of a study, but a chain of decisions made from the moment a question is conceived to the point at which findings are communicated to the public. Errors can occur at every stage: the question may be ill-posed, the design may be incapable of answering it, the measurements may be weak, the analys
#603: Should Dietary Fiber Be Considered Essential? – Andrew Reynolds, PhD Apr 28, 2026 59:14 Dietary fiber is widely recognized as an important component of a healthy diet, yet it is not typically classified as an essential nutrient. In this episode, Dr. Andrew Reynolds explores whether that distinction still holds, arguing that the traditional criteria used to define essentiality may be outdated when applied to modern nutrition science. The discussion moves beyond simply acknowledging th
#602: Avoidant/Restrictive Food Intake Disorder (ARFID) – Megan Hellner, DrPH, RD & Katherine Hill, MD Apr 21, 2026 50:27 Avoidant/Restrictive Food Intake Disorder (ARFID) is an eating disorder diagnosis characterized by a persistent restriction or avoidance of food intake that results in clinically significant consequences (medical, nutritional, and/or psychosocial), but without the weight- and shape-driven psychopathology typical of anorexia nervosa and bulimia nervosa. In this episode, Megan Hellner and Katherine
#601: Gallstones & Gallbladder Conditions: Impact of Diet – Angela Madden, PhD RD Apr 14, 2026 53:26 This episode examines what we actually know (and importantly, what we do not know) about diet in relation to gallstones and gallbladder conditions. Much of the public-facing guidance around gallstones focuses on "avoiding fatty foods", yet Dr. Angela Madden explains that this long-standing practice sits on surprisingly weak direct evidence, particularly when judged against the standards typically
Coevolution With Foods? Multivitamins? Eating Too Early? – Ask Me Anything (SNP49) Apr 7, 2026 22:09 In this episode, Danny answers questions submitted by Premium subscribers. Questions Answered in This Episode: [00:05:13] Is eating too early (relative to chronotype) metabolically problematic? [00:16:55] Can plant-based diets reverse cardiovascular disease? [00:32:54] Are multivitamins useful insurance, or a waste with a good diet? [00:44:56] Does coevolution with foods determine human compatibi
#600: Finite Knowledge, Infinite Ignorance Mar 31, 2026 02:00:12 "The more we learn about the world, and the deeper our learning, the more conscious, specific, and articulate will be our knowledge of what we do not know, our knowledge of our ignorance. For this, indeed, is the main source of our ignorance — the fact that our knowledge can be only finite, while our ignorance must necessarily be infinite." – Karl Popper To mark Sigma Nutrition's milestone 600th e

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