Home Podcasts Biohacking Beauty: The Anti-Aging Skincare Podcast
Biohacking Beauty: The Anti-Aging Skincare Podcast

Biohacking Beauty: The Anti-Aging Skincare Podcast

Young Goose 255 Episodes Jul 22, 2026

Biohacking Beauty is a podcast that explores skin health through the lens of longevity medicine and cellular biology. Hosted by the founders of Young Goose, Amitay Eshel and Anastasia Khodzhaeva, it delves into multi-mechanism protocols for optimizing the skin. The show features world-renowned experts in mitochondrial health, epigenetic signaling, and regenerative medicine, translating complex research into actionable strategies. Topics include the 12 Hallmarks of Aging and bio-harmonizing lifestyle shifts for biological recalibration.

Episodes

263. Q&A: The Skincare Trends Worth Questioning Before You Buy
263. Q&A: The Skincare Trends Worth Questioning Before You Buy Jul 22, 2026 33:41 Skincare trends are moving fast, and it can be hard to tell what is actually worth your attention. One day everyone is talking about red light masks, then peptide lip balms, at-home microneedling, men’s skincare, acne protocols, or another product claiming to be the next thing your skin needs.The problem is that some of these tools can be useful, but the way they are marketed often leaves out the
262. Chris Duffin: The Peptide Mistake That Keeps Regenerative Protocols From Working
262. Chris Duffin: The Peptide Mistake That Keeps Regenerative Protocols From Working Jul 15, 2026 01:10:10 Peptides are being treated like the missing piece in recovery, skin longevity, fat loss, performance, and aging. The usual belief is that if you find the right compound, the right dose, or the right stack, the body will finally respond the way you want it to. But what if the protocol is not the first thing that needs to be fixed?In this episode of Biohacking Beauty, I sit down with Chris Duffin to
261. Reacting To Allure’s LED Mask Advice: What To Know Before Spending Money On a LED Mask
261. Reacting To Allure’s LED Mask Advice: What To Know Before Spending Money On a LED Mask Jul 8, 2026 19:16 If you have been thinking about buying a LED mask, the hardest part is knowing what actually matters. The price range is all over the place, every brand seems to have some version of “FDA cleared” on the page, and a lot of the buying advice sounds scientific enough to trust. But none of that automatically tells you whether the device is strong enough to do anything meaningful for your skin.That is
260. Dr. Jennifer Berman: Peptides, Hormones, and the Anti-Aging Protocol Most Women Start Too Late
260. Dr. Jennifer Berman: Peptides, Hormones, and the Anti-Aging Protocol Most Women Start Too Late Jul 1, 2026 01:05:00 We have been getting the same question in our DMs for months now. Peptides are everywhere. Everyone is talking about them. But what actually has evidence behind it, what is hype, and where do hormones fit into all of this? So we went and found someone who has been living this conversation for 35 years, not just talking about it.Dr. Jennifer Berman is a urologist, New York Times bestselling author,
259. Dr. Dan Pardi: How Creatine Supports Brain Function, Skin Health, and DNA Repair
259. Dr. Dan Pardi: How Creatine Supports Brain Function, Skin Health, and DNA Repair Jun 24, 2026 51:36 Creatine has been boxed in as a gym-bro supplement for decades, but the latest research shows it's doing far more than building muscle. It buffers brain energy under sleep deprivation, supporting bone density and mood stability through perimenopause, and freeing up methyl groups for detoxification and DNA repair.We dive deeper into this in the Biohacking Beauty Podcast with Dr. Dan Pardi. We also
258. SPF Is Not Enough: The Cellular Repair Protocol Your Skin Needs This Summer
258. SPF Is Not Enough: The Cellular Repair Protocol Your Skin Needs This Summer Jun 17, 2026 39:04 When summer skin starts looking dull, congested, tired, or slower to recover, it is easy to blame the obvious things: heat, sweat, sunscreen, long days outside, or the wrong moisturizer. So the conversation usually stays on the surface. Use SPF. Cleanse better. Switch to lighter products. Add antioxidants. But before we treat summer skin like another product problem, there is a deeper question wor
257. The Mitochondria Problem Behind Aging Skin + How to Recharge Your Skin and Look Younger
257. The Mitochondria Problem Behind Aging Skin + How to Recharge Your Skin and Look Younger Jun 10, 2026 34:30 Every fibroblast inside your dermis right now is asking 200 to 2,000 mitochondria to power its work in real time, and those mitochondria are descendants of a free-living bacterium swallowed by a larger cell 2 billion years ago. As you age, those mitochondria run slower and your cells build fewer of them to replace the ones that fail.In this solo episode, Young Goose co-founder Amitay Eshel breaks
Dr. Tyler Panzner: Hidden Trade-Offs of Longevity Supplements and the Advantage of Topical Delivery
Dr. Tyler Panzner: Hidden Trade-Offs of Longevity Supplements and the Advantage of Topical Delivery Jun 3, 2026 01:09:30 Roughly 25% to 30% of the population carries slow variants in the MAOA or COMT genes, the two enzymes responsible for clearing adrenaline, dopamine, and serotonin from the brain.For these individuals, common polyphenols marketed for inflammation and longevity, including curcumin, act as weak MAOA inhibitors that further slow neurotransmitter breakdown. The result is a quiet buildup of stimulation
The Death of Anti-Aging Skincare & The Longevity Framework That Replaces It
The Death of Anti-Aging Skincare & The Longevity Framework That Replaces It May 29, 2026 45:47 Your skin has a biological age and for most people, it's not the same as their chronological one. Mayo Clinic published the SkinSpan framework this year specifically to quantify it, and the 12 Hallmarks of Aging now have a direct application to dermal tissue.This raises an uncomfortable question: if you're already optimizing everything below the neck with NAD IVs, peptides, and red light, why is t
The Overlooked Side of Autophagy Causing Aging - Part 2
The Overlooked Side of Autophagy Causing Aging - Part 2 May 27, 2026 31:03 The melanocytes giving pigment to your skin right now might be older than your car. They have been sitting in your dermis for decades, and unlike the cells on your skin's surface, they do not get replaced. They have to keep themselves clean which happens through autophagy.In Part 2 of our autophagy deep dive, we get specific about how skin handles autophagy differently from other parts of the body
The Overlooked Side of Autophagy Causing Aging - Part 1
The Overlooked Side of Autophagy Causing Aging - Part 1 May 20, 2026 26:17 What if your skin could literally rebuild itself from the inside out? In this episode, we break down one of the most powerful and misunderstood biological processes in the human body: autophagy.From its Nobel Prize-winning discovery to the molecular machinery that drives it, we walk you through exactly what autophagy is, how it works at the cellular level, and why it matters far more than most peo
Chris Mirabile: Why One Ingredient Will Never Stop You From Aging (And What Actually Does)
Chris Mirabile: Why One Ingredient Will Never Stop You From Aging (And What Actually Does) May 13, 2026 51:18 Most of what the supplement and skincare industry sells for aging targets one pathway at a time. But your biology does not age that way. It declines across 12 interconnected processes simultaneously, and by the time one of them shows up on your skin, the others have already been running for years.We at Young Goose believe that skin longevity is not a topical problem. It is a whole biology problem,

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