Tiny Matters
Tiny Matters is an award-winning science podcast from the American Chemical Society that explores the hidden impact of tiny things—from molecules to microbes—on society. Hosted by former scientists Sam Jones and Deboki Chakravarti, each episode delves into topics like infectious disease, IVF, glaciers, and smallpox eradication. The show embraces the awe and messiness of science, both historical and modern. New episodes are released every Wednesday.
Episodes
Giant viruses: How these amoeba-infecting behemoths are rewriting the rules of virology
Scientists spent decades searching for viruses by filtering out anything too large to be one. That strategy seemed to work well... until it didn't. When researchers discovered a microbe living inside an amoeba that looked like a bacterium but behaved like something else entirely, they uncovered a hidden world of giant viruses with massive genomes, unusual genes, and even their own viral p
[BONUS] Fairy tale evolution and the 400(ish) year old elusive Greenland shark: Tiny Show and Tell Us #53
In this episode of Tiny Show and Tell Us, we explore how scientists are using evolutionary methods to reconstruct the history of folktales like Little Red Riding Hood, Beauty and the Beast, and Jack and the Beanstalk. Then guest Matt Gabriele, professor of medieval studies and host of the podcast American Medieval, shares his fascination with Greenland sharks, leading us into the science
From cow’s milk to blood banks: The surprising evolution of blood transfusions
Before modern blood transfusions, doctors tried some odd alternatives, including cow's milk. In this episode, we trace the fascinating history of blood transfusions, from risky animal experiments and failed milk injections to the discovery of blood types and disease screening. You'll hear how blood transfusions became one of medicine's safest procedures, why researchers are still debating
[BONUS] Bread clip taxonomy and power poles on fire: Tiny Show and Tell Us #52
In this episode of Tiny Show and Tell Us, we dive into the surprisingly elaborate world of occlupanids: the humble plastic bread bag clips that have inspired an entire taxonomy complete with Latin names, species classifications, and a community of collectors. Then, we investigate a strange power outage in central Texas, where power poles caught fire after a light drizzle. We unpack the sc
Placebo: Why ‘fake’ treatments can have real power
A sugar pill shouldn't work as well as a real drug ... except sometimes it does. In this episode, we explore the fascinating science of the placebo effect and how expectations can shape biological outcomes. From open-label placebos and AI healthcare chatbots to the nocebo effect, we unpack what scientists know, what they still don't understand, and why the placebo response is still largel
[BONUS] A pathology lab, a sausage duel, and the fascinating lives of yeast: Tiny Show and Tell Us #51
In this episode of Tiny Matters, a listener who works in a pathology lab explains how even the ickiest specimens become ho-hum with time, sending Sam and Deboki down a rabbit hole of pathology history and the bizarre life of Rudolf Virchow, the “father of pathology” who was also rumored to have brought worm-filled sausages to a duel. Then, a listener's sourdough experiments spark a conver
Fireworks over millennia: From battlefields and royal displays to sustainable spectacles
In medieval Europe, people who worked with early cannons and gunpowder were viewed as untrustworthy, boorish outsiders. But just a few centuries later, as they began creating elaborate fireworks displays for royalty, they went from outcasts to artists. From black powder to modern low-smoke pyrotechnics, in this episode of Tiny Matters we look at the chemistry, engineering, and artistry be
[BONUS] The ‘elite neutralizers’ immune to HIV and why galaxies ‘FART’: Tiny Show and Tell Us #50
This week on Tiny Show and Tell Us, a listener introduces us to "FARTs" — a silly acronym for galactic gas outflows — and sends us down a rabbit hole of dying stars and recycled cosmic gas in the early universe. Then we discuss the decades-long search for broadly neutralizing antibodies (bNAbs) that can target many HIV strains at once. One bNAb that looks promising is in clinical trials r
Collisions in space: Satellites, space debris, and the quest to clean up Earth's orbit
We tend to think of space as vast and mostly empty, yet the region just above Earth is far from it. In this episode, we explore the surprising congestion of low Earth orbit, where tens of thousands of satellites and millions of pieces of debris are hurtling around at incredible speeds. From a major satellite collision in 2009 to the looming threat of the Kessler Effect — where Earth’s orb
[BONUS] A nitrogen asphyxiation disaster and why ears are incredible: Tiny Show and Tell Us #49
In this episode of Tiny Show and Tell Us, we unpack a tragic NASA accident in 1981 when technicians, preparing for the maiden voyage of Space Shuttle Columbia, were accidentally poisoned by nitrogen gas. Then guest Mischa Stanton takes us deep inside the human ear. We talk about how vibrations turn into thoughts via the cochlea and basilar membrane and dive into the fascinating world of l
The Challenger disaster: How a NASA tragedy led to a safer Artemis II
When Artemis II lifted off this past April, marking humanity’s return to the Moon, people across the world were captivated. It was a triumph decades in the making, but also shaped by painful loss. In this episode of Tiny Matters, we trace the legacy of the Space Shuttle Challenger disaster on its 40th anniversary, unpacking what went wrong both scientifically and organizationally, and how
[BONUS] The ‘Plankton Manifesto’ and the birth of MRI: Tiny Show and Tell Us #48
In this episode of Tiny Show and Tell Us, we dive into the Plankton Manifesto and why these drifting, diverse organisms are so essential to life on Earth. Then we trace the nuclear magnetic resonance (NMR) roots of MRI, through a listener’s personal experience as a patient and chemist.Check out This Guy Sucked here or wherever you get podcasts!We need your stories — they're what make
When movies caught fire: The history and science of nitrocellulose film
Did you know that over 75% of silent films have disappeared? The culprit: highly flammable film! We open this episode of Tiny Matters with a poker bet, a decades long grudge, and a garage full of film before we hop into the rise of nitrate (nitrocellulose) film and how it shaped film history. We chat with Robert Shanebrook, who literally wrote the book on Kodak film, and with collection m
[BONUS] Von Willebrand disease and how old is the air in your lungs?: Tiny Show and Tell Us #47
In this episode of Tiny Show and Tell Us, a listener asks: Could we still be carrying air from our very first breath? Deboki unpacks residual lung volume, gas exchange, and a forensic technique used to determine whether or not someone drowned. Then, the conversation turns to women’s health and bleeding disorders after a listener shares their experience living with Von Willebrand disease —
‘Clean beauty’: Cosmetics, chemophobia and the anti-vax pipeline
In the early 1930s, a “new and improved” eyelash dye called Lash Lure blinded more than a dozen women, ultimately forcing the FDA to pass new regulations on cosmetics. Nearly a century later, beauty remains far safer than it was in the past, but you could argue that beauty marketing has become far more insidious, with vague language and chemophobic claims to push consumers toward products
[BONUS] The Chemists’ Wars: The Origin Story of Chemistry
Have you checked out ACS' new podcast Chain Reaction? Today we're bringing Tiny Matters listeners one of our favorite episodes! Chemistry doesn’t just shape conflict — conflict shapes chemistry. And at no time in history is that more apparent than during the two world wars. Historian Alison McManus recounts how the race to weaponize toxic gases like chlorine and mustard gas transformed ch
[BONUS] Antarctic dinosaurs, blood restriction therapy, and an HIV prevention breakthrough: Tiny Show and Tell Us #46
In this episode of Tiny Show and Tell Us, we welcome our first‑ever guest, podcast producer and dinosaur enthusiast Steven Ray Morris. Together, we dive into three wildly different stories. First, we explore a major advancement in HIV prevention: a newly approved twice‑yearly injectable drug called Lenacapavir. We chat about how it works, why it’s a huge shift from daily pills or monthly
Deep-sea mining: Environmental uncertainty, ‘Law of the Sea,’ and shark potatoes
In this episode, we dive into the murky, high‑stakes world of deep-sea mining — the practice of extracting valuable metals from the ocean floor. Deep-sea mining has been “just around the corner” for decades. So what’s the holdup? With the help of deep-sea ecologist Andrew Thaler and oceanography researcher Michael Dowd, we discuss what makes the deep ocean such a challenging place to oper
[BONUS] The history of Turner Syndrome and engineering food for bees: Tiny Show and Tell Us #45
In this episode of Tiny Show and Tell Us, we trace the history of Turner Syndrome — from early clinical observations to the discovery of its chromosomal cause — highlighting how scientists began connecting symptoms to genetics long before DNA was fully understood. Then we follow up on a listener note about lab safety by explaining, at a molecular level, why dimethylmercury and prions are
How soap shaped civilizations — and ‘ruined’ famous art
In the heart of The Hague, Netherlands, the museum Mauritshuis displays some of the world’s most iconic art in its Royal Cabinet of Paintings, including ones from Rembrandt and Vermeer’s Girl with a Pearl Earring. But there’s another oil painting by Vermeer that is also quite famous, called View of Delft — it's of his hometown, created around 1660.The painting is a cityscape — the only on
[BONUS] Camel antibodies and colorful Greco-Roman statues: Tiny Show and Tell Us #44
In this episode of Tiny Show and Tell Us, we explore the strange world of camelid antibodies—tiny, heavy-chain-only immune molecules that turned out to be incredibly useful for research and medicine. Then we chat about archaeochemistry and how pristine white Greco-Roman statues were once "garishly" painted. Using modern chemical techniques, scientists are revealing traces of vivid pigment
Stinky white gold, Haber-Bosch, and ‘peecycling’: How fertilizer shapes our world
Fertilizer… boring? Not on our watch! In this episode of Tiny Matters, we trace the history of fertilizer from the ‘Guano Wars’ to the invention of the Haber-Bosch process, one of the most impactful chemical breakthroughs in human history. Today, scientists and communities are rethinking how we handle nutrients, and asking: could our own urine help close the nutrient loop? We chat with ch
[BONUS] Reef balls and peanut allergy immunotherapy: Tiny Show and Tell Us #43
In this episode of Tiny Show and Tell Us, we explore a listener's experience with peanut allergy immunotherapy — what it is, how the therapy works, and the odd and fascinating history of allergy treatments, including a 19th‑century scientist who shoved grass pollen up his own nose. Then we chat about “reef balls” made of oyster shells and concrete. These mini artificial reefs are being us
The Mothers of Gynecology: The centuries that led to today’s Black maternal mortality crisis
In this special crossover episode, Tiny Matters welcomes Alexis Pedrick, host of Distillations from the Science History Institute. You’ll hear the Distillations episode “The Mothers of Gynecology” — a powerful investigation into the racist origins of gynecology and the ongoing maternal health care crisis that disproportionately affects Black mothers. Through interviews with historians, cl
A new podcast joining the fam: Chain Reaction by ACS!
Chain Reaction is a new podcast from the American Chemical Society that links chemistry’s past to its future, revealing how this ever‑evolving science shapes the world around us, from the materials we use every day to the environment that we depend on. Each episode brings fresh perspectives and personal stories from chemists, engineers, and other scientists, as well as historians who guid
[BONUS] 5D storage in the ‘Memory of Mankind’ and the root of morning sickness: Tiny Show and Tell Us #42
In this episode of Tiny Show and Tell Us, we go from nerdy house-party physics to the brutal realities of morning sickness (can you say range!). First, we unpack what 5D data storage is and debate what we’d personally toss into the “Memory of Mankind” salt mine in Austria. Then we tackle a listener’s question about whether science has any updates on what causes severe morning sickness.&nb
Inside expedition medicine: Keeping people alive in the harshest places on Earth
In 2019, Nathan Hudson-Peacock was serving as an expedition doctor to a group hiking in the Indian Himalayas. At around 17,000 feet, a climber suddenly went from having a mild headache to a life‑threatening cerebral edema. On top of that, a storm was closing in. So, what did he do? How do expedition doctors keep people alive in the harshest places on Earth? Tune in to this week’s episode
[BONUS] 'Mitochondrial Eve' and birds stealing anti-bird spikes: Tiny Show and Tell Us #41
In this episode of Tiny Show and Tell Us, we talk about the crafty corvids that steal anti‑bird spikes to build chaotic, spiky nests and “Mitochondrial Eve” — the most recent common maternal ancestor of modern humans. Get ready for stories of sandwich‑stealing gulls, Deboki being held hostage by a peacock, and the Mitochondrial Eve/Y Chromosomal Adam romcom no one asked for.We need your s
From ancient grain mills to massive offshore turbines: Why wind energy was — and still is — a big deal
For over a thousand years, humans have been harnessing wind energy. It may have begun with small, grain‑grinding windmills in ancient Persia, but today you might spot Hoover‑Dam‑sized offshore turbines as you drive along the east coast. How did we get here? In this episode of Tiny Matters, we explore the first electric wind turbines built in the late 1800s, how government policies in the
[BONUS] Dandelion rubber tires and a fentanyl vaccine: Tiny Show and Tell Us #40
In this episode of Tiny Show and Tell Us, we explore a listener’s tip about a new source of tire rubber — the Russian dandelion — and the science behind what makes it such an incredible and sustainable source of natural latex rubber. Then we answer a listener’s question about a vaccine for fentanyl that will stop the drug from reaching the brain, preventing overdose.We need your stories —
The history of clinical trials: From fake exorcisms to testing today
In 1599, a family in a small French town claimed that their daughter was possessed by a demon called Beelzebub and, despite daily exorcisms, the demon possessing this woman was staying put. So France’s Henri IV set up a royal commission that would try something a little different. The woman would still receive exorcisms, complete with the normal exorcism accoutrements, but with a catch. T
[BONUS] Bat periods and toxins from fungi: Tiny Show and Tell Us #39
In this episode of Tiny Show and Tell Us, we learn that humans aren’t the only mammals who menstruate. We explore the fulvous fruit bat’s 33‑day cycle, how reproductive biology differs across species, and why scientists still don’t fully understand why menstruation evolved in the first place. Then we take a deep dive into the world of mycotoxins: dangerous compounds produced by fungi. We
The iron lung: How a hulking metal tube became the first machine to keep humans alive
It’s no exaggeration to say that polio shaped modern medicine. Before a vaccine was available, polio outbreaks left thousands of people paralyzed, with some unable to breathe. But, in 1928, the development of the iron lung meant that, for the first time, humans could rely on a machine to stay alive. In this episode, we trace the rise of polio in the early 20th century, the science behind
[BONUS] The woman who mapped the Milky Way and a toxic evolutionary showdown: Tiny Show and Tell Us #38
In this episode of Tiny Show and Tell Us, we kick things off with a quick shout-out to a listener who started flossing thanks to a previous episode. Then we dive into the hidden history of the women “computers” at Harvard Observatory, including Henrietta Leavitt, who laid the foundation for modern astronomy with her groundbreaking discoveries including calculating the size of the Milky Wa
Sam’s brain-altering bacteria and Deboki’s polio vaccine fascination: EPISODE 100!
In this milestone 100th episode of Tiny Matters we take you on a personal journey into what first inspired our passion for science. Sam shares the story of her childhood struggle with germophobia and the brain-altering bacteria that kicked it off, likely causing a condition called PANDAS: Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections. PANDAS may
[BONUS] Bunny pregnancy tests and a dead salmon MRI: Tiny Show and Tell Us #37
In this episode of Tiny Show and Tell Us, we read an email from “baby sis” aka Binky aka Sam’s younger sister Caroline who writes in about an alarming pregnancy test that predates today’s at-home tests. Then we talk about a fascinating study that found a dead salmon showed brain activity in an MRI machine. Spoiler: It wasn’t actually alive, scientists just really needed to rethink MRI ana
How life keeps time: Zeitgebers, hidden clocks, and ugh daylight saving
Not a fan of daylight saving? Beyond the depressingly early sunsets, that may be because it’s messing with your circadian clock. In this episode of Tiny Matters, we ask, “How do organisms — from bacteria to sea anemones to humans — keep track of time?” We talk about circadian clocks and how both internal molecular changes and environmental cues called “zeitgebers,” which include things li
[BONUS] Polar bear fact vindication and vibrating insects: Tiny Show and Tell Us #36
In this episode of Tiny Show and Tell Us, we read an email from a listener who, as a kid, shared a fun fact with her classroom: polar bears have black skin. Her teacher not only told her she was wrong but embarrassed her in front of the other students. Well, it’s time to set the record straight. Polar bears do, in fact, have black skin and we do, in fact, love a grudge and are so glad to
Dinner with King Tut: How experimental archaeologists are recreating the past
In today’s episode, we chat with author Sam Kean about his new book Dinner with King Tut and learn how researchers and citizen scientists are recreating ancient recipes, tools, and technologies — from wound remedies with pennies to inventive pottery glazed in blood — and how experimental archaeology is changing our understanding of the past. Send us your science facts, news, or other
[BONUS] Making magenta pennies and touching the sun: Tiny Show and Tell Us #35
In this episode of Tiny Show and Tell Us, we talk about different ways of turning pennies all of the colors of the rainbow. Then we discuss an ongoing NASA mission to touch the sun.We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.
What's eating the Titanic?
Most of us know the story of the Titanic. In 1912, the massive — supposedly indestructible — steamship sank after hitting an iceberg on its first and only journey across the Atlantic Ocean. Titanic remained undiscovered on the seafloor, somewhere in the North Atlantic Ocean, for 73 years, until it was found nearly two miles beneath the surface. But now the ship might be disappearing again
[BONUS] 4 years of Tiny Matters?! How we started, what we've learned, and where we're headed!
As we approach episode 100 of Tiny Matters, we wanted to talk about how it all got started nearly 4 years ago and where we are headed! How did Sam and Deboki become co-hosts? What have they learned about the types of stories and episodes they are drawn to? What happens if an interview goes poorly? What is the American Chemical Society (ACS)? How about Multitude? Will we get 100 MORE episo
New male contraceptives could be here soon. What took so long?
If you’re a female and you want to use a contraceptive pill, patch, injection, or device, you have over 250 options. But if you’re a male and you want a contraceptive, you have three options. You can get a vasectomy, you can use condoms, which can have up to a 18% failure rate, or you can use what sex researchers politely call “the withdrawal method,” which is highly unreliable. But there
[BONUS] Why horseshoe crab blood is blue, HELLP syndrome, and a one-electron bond: Tiny Show and Tell Us #34
In this episode of Tiny Show and Tell Us, a listener writes in to tell us about being born 3 months premature likely due to their mom having HELLP syndrome, a variant of preeclampsia, and taking part in early trials for surfactants. Then we discuss why horseshoe crab blood is blue and the exciting generation of a one-electron bond between carbon atoms. We need your stories — they're
Trade, tyranny, and untapped potential: The history and science of spices
For thousands of years, the rise and fall of empires and the global economy were closely tied to something you might not expect: spices. The spice trade began around 1000 BCE, localized to southeast Asia and the Middle East. But by the beginning of the next millennia, it had rapidly expanded and nations vied to control it. Today it’s typically far less work to find and purchase spices you
[BONUS] Fluorescent milk, ‘liquid’ glass, and studying ripples in spacetime: Tiny Show and Tell Us #33
In this episode of Tiny Show and Tell Us, we get to the bottom of if glass is a liquid or a solid and why riboflavin makes milk fluorescent. Then we talk about the Laser Interferometer Space Antenna (LISA) — the first space-based observatory that NASA scientists and their collaborators are sending up into space to detect and study gravitational waves, better known as “ripples in spacetime
How stunning 19th century dyes led to today's drugs
In 1856, after yet another day of disappointing experiments, a chemist named William Henry Perkin was cleaning up his glassware when he made a discovery that would harken a new — and colorful — era of science and industry. Just 18 years old, Perkin was a promising young student in a prestigious lab at the Royal College of Chemistry in London and he was supposed to be figuring out a way to
[BONUS] Wasp versus beetle and blood iron recycling: Tiny Show and Tell Us #32
In this episode of Tiny Show and Tell Us, a listener on “team wasp” writes in with some interesting info on USDA wasps for pesticide-free pest control and we learn about some wasp versus beetle drama. Then we talk about how our red blood cells use and expel iron, and how a huge percentage of the iron we get is from broken down blood cells.We need your stories — they're what make these bon
De-extinction: Genetics, conservation, and lessons from 'dire wolves'
Back in April, a company called Colossal Biosciences announced that they had brought dire wolves — ancient canines of Game of Thrones fame — back from extinction. The internet went wild. But while some media outlets proclaimed the return of a long-gone species, many scientists shot back on social media that these weren’t really dire wolves, they were just genetically engineered grey wolve
[BONUS] Woolly mammoth mice and filtering microplastics out of your water: Tiny Show and Tell Us #31
In this episode of Tiny Show and Tell Us, we talk about cute woolly mammoth mice and debate whether research to bring back extinct species (or their genes) is ethical or a good use of money and time. Then we discuss the best way to remove microplastics from water. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form
Zircon: How this tiny, ancient mineral is upending what scientists believed about early Earth
How did the early Earth, over four billion years ago, evolve into the planet we know and love today? It’s a big question, and an open question. To get answers, geologists turn to a surprising source — a tiny mineral no bigger than the diameter of a human hair, that has secrets about our planet locked away in its crystal structure. This miniscule mineral, with its big stories is called zir
[BONUS] Biodegradable super glue and a severe greenhouse gas that lowers your voice: Tiny Show and Tell Us #30
In this episode of Tiny Show and Tell Us, we talk about a new and exciting biodegradable polymer that seems to outperform commercial super glues. Then we discuss a compound called sulfur hexafluoride (SF6) that is used in high voltage equipment. Not only is SF6 a potent greenhouse gas, if you breathe it in it has the opposite effect of helium — it makes your voice deep. But it can also le
Is ‘mom brain’ … forever?
An estimated 132 million babies were born across the globe last year — really just a drop in the bucket when you think about the over 100 billion babies born since modern humans first lived on Earth 200,000 years ago. And until very recently we had few tools to understand how they were doing in the womb, how they would fare in the days after birth, and how a pregnant person would change p
[BONUS] Birds breathing with their butts and reducing food waste to combat climate change: Tiny Show and Tell Us #29
In this episode of Tiny Show and Tell Us, we talk about breathing in birds — how it takes two breath cycles for air to leave their bodies, and while it travels within their bodies, it's stored in various sacks, some of which are in their butts. Then we discuss how food waste contributes to approximately 8% of global greenhouse gas emissions every year, and what we can do to reduce it.&nbs
How domesticated is a domestic cat? From the wild to ancient Egyptian tombs to now
3,500 years ago, cats started showing up in Egyptian paintings on tomb walls and in sculptures and carvings. Not only were they abundant in these representations, but it was very clear that they were domestic. They had collars around their necks and were eating out of food dishes underneath the dining room table. That scene is not so different from the life many cats lead today. So how di
[BONUS] Diamond rain on Saturn (maybe) and UV rays breaking down harmful dyes: Tiny Show and Tell Us #28
In this episode of Tiny Show and Tell Us, we tackle the debate surrounding whether or not it rains diamonds on Saturn. Then we talk about how UV degradation can break down some of the harmful residual dyes from plastic pollution, and what it means in the context of microplastics. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fi
The strange science and history of quantum computing and how it could transform chemistry
On May 7, 1981, influential physicist Richard Feynman gave a keynote speech at Caltech. Feynman opened his talk by politely rejecting the very notion of a keynote speech, instead saying that he had his own ideas on what to discuss and that everyone should speak on what they please. And for Feynman, this meant proposing a new technology that could simulate physics with computers. That lect
[BONUS] Squirrel pox and did tin buttons cause the downfall of Napoleon's army?: Tiny Show and Tell Us #27
In this episode of Tiny Show and Tell Us, we cover squirrel pox — a disease that hasn’t had a huge impact in the United States but has decimated populations of squirrels in the UK. Then we talk about the story that Napoleon's army lost the Battle of Waterloo because the military uniforms used tin buttons that broke apart in cold temperatures, making it harder for the troops to survive. Bu
Making labs safer: A heavy metal poisoning, a deadly protein exposure, and their aftermath
In January, 1997, David Nierenberg was a physician at Dartmouth‐Hitchcock Medical Center, specializing in toxicology. Chemist Karen Wetterhahn was placed in his care. When she arrived at the hospital, Karen was slurring her speech and having difficulty balancing and with coordination. What David soon learned was that her symptoms were all due to a few tiny drops of a compound called dimet
[BONUS] Fetuses ‘listening’ to different languages and climate change affecting psychiatric meds: Tiny Show and Tell Us #26
In this episode of Tiny Show and Tell Us, we talk about how climate change may impact the effectiveness of mental health medications and how heat waves impact mental health more generally. Then we cover how fetal heart rates can change depending on which language they’re hearing while in the womb. We need your stories — they're what make these bonus episodes possible! Write in to tinymatt
How NASA scientists are monitoring and predicting wildfires from space
Climate change has brought forth extreme fire events, like the Palisade and Eaton fires in Los Angeles, which devastated communities in Altadena and the Pacific Palisades in the beginning of 2025. And it’s becoming harder to not wonder: Is this just the world we live in now? Under the constant threat of catastrophic fires? Fortunately, we have the perfect guests to answer that question. W
[BONUS] The FDA’s ban of Red Dye No. 3 and the surprising science of winter roads: Tiny Show and Tell Us #25
In this episode of Tiny Show and Tell Us, we talk about why the FDA recently banned Red Dye No. 3 and how concerned people should be about its use in food. Then we cover icy winter roads and the fascinating science behind clearing them and taking a more sustainable approach that won’t hurt the environment.We need your stories — they're what make these bonus episodes possible! Write in to
How a Mars mission from the 1970s shaped the search for extraterrestrial life today
In 1975, NASA launched two spacecraft to Mars. Viking 1 and Viking 2 arrived at their destination less than a year later, each bringing a lander to explore the surface of the planet and an orbiter to survey above. What was supposed to be a 90 day mission ended up lasting until the early 1980s. Those years provided scientists with important data about the Martian landscape, from seismomete
[BONUS] Babies leaving cells behind in mom and rethinking the Big Bang: Tiny Show and Tell Us #24
In this episode of Tiny Show and Tell Us, we talk about what dark energy and dark matter are made out of and how knowing more could upend our understanding of the Big Bang. Then we cover microchimeric cells — cells transferred between baby and mom — and how new research in mice shows that fetal cells that took residency in mom from a first pregnancy are replaced by new fetal cells of a se
Ozempic: The science behind this blockbuster drug and its untapped potential
In December 2017, the FDA approved a new injectable drug to treat type 2 diabetes called semaglutide, which you likely know by its brand name: Ozempic. A few years later, during the pandemic, Wegovy, a drug with a higher dose of the same active ingredient, was approved specifically for chronic weight management. Soon after, people taking Ozempic started reporting a dramatic, even “life-ch
[BONUS] Marfan syndrome and plant pathogens eating DNA: Tiny Show and Tell Us #23
In this episode of Tiny Show and Tell Us, we hear from a listener who has Marfan syndrome and dive into the complexities of the disease. Then we talk about pathogens that eat — or infiltrate! — plant DNA.We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a
How a little-known vaccine project and decades of HIV research made "Operation Warp Speed" possible
Over the last 200 years or so, vaccines have come a long way, for a number of viruses. We’ve made so much progress, in fact, that in 2017 scientists began the early stages of vaccine development for some virus families they believed could pose a future pandemic threat. One of those families was Coronaviridae: coronaviruses. Not many people know that before SARS-CoV-2 started making its wa
[BONUS] Time limits for anesthesia and stunning bioluminescence: Tiny Show and Tell Us #22
In this episode of Tiny Show and Tell Us, we break down what limits on anesthesia could mean, both for doctors and patients. Then we hear from a listener who’s on a research trip in Puerto Rico and went kayaking in a bioluminescent bay. What is bioluminescence? And what are the perfect conditions to try to see it?We need your stories — they're what make these bonus episodes possible! Writ
The placenta: A disposable organ we can’t live without
The placenta is essential for life, but so much of its function is unknown. In this episode, we talk about how this disposable organ’s development within the early weeks of pregnancy shapes so much of what happens months later. We tackle what makes the human placenta so unique, what other animals like reptiles are teaching us about it, and how scientists are turning to evolution and compu
[BONUS] An inspiring pharmacist grandma and orcas wearing dead salmon hats: Tiny Show and Tell Us #21
In this episode of Tiny Show and Tell Us, we hear from a listener about her incredible grandma who’s a pharmacist in Venezuela (still, at 92 years old!) and has inspired her love of science and current lab work. We then talk about orcas spotted wearing dead salmon as hats, and what this fishy behavior may mean. We need your stories — they're what make these bonus episodes possible! W
How glaciers safeguard Earth’s future and hold clues to our ancient past
The reason many of us hear about glaciers has to do with sea level rise — which makes sense! If all of the glaciers on Earth melted, sea levels are predicted to increase by about 230 feet (70 meters), which would flood coastal areas, envelope a number of islands, and seriously impact human infrastructure, including our current water resources. But glaciers do more than safeguard Earth’s f
[BONUS] Evolutionary adaptations to high altitudes and e-cigs vs. dry herb vaporizers: Tiny Show and Tell Us #20
In this episode of Tiny Show and Tell Us, we discuss the differences between e-cigarettes (vapes) and far-less-studied dry herb vaporizers. Then we talk about some of the incredible evolutionary adaptations of populations of people living at high altitudes. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form*
How 18th and 19th century 'race science' still has deadly medical consequences today
In the 1700s and early 1800s scientists from Europe and the Americas were studying what they called "race science," a pseudoscientific field of study promoting the idea that humans could be divided into separate and unequal races. Biases stemming from race science have influenced medicine for hundreds of years, and still have deadly consequences today. In this episode of Tiny Matters
[BONUS] Crocheted wasp nests and sewage in reefs: Tiny Show and Tell Us #19
In this episode of Tiny Show and Tell Us, we discuss if a crocheted wasp nest could actually attract wasps and keep them from invading your property. Then we talk about how sewage is impacting the resilience of coral reefs.We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or scien
The rape kit: From controversial 1970s invention to ending the backlog today
In the 1970s, the rape kit began as a simple box with some envelopes, a comb, nail clippers, and a few other basic tools. The contents of the kit have evolved somewhat since then, but the technology to analyze samples has evolved astronomically. And, through and through, the rape kit has stood for the idea that every survivor has the right to go to a hospital, get a full forensic exam, an
[BONUS] Double rainbows and mysterious chromosomes: Tiny Show and Tell Us #18
In this episode of Tiny Show and Tell Us, we cover the science of rainbows and why double rainbows are always mirror images. Then we talk about mysterious, yet super common, chromosomes called Robertsonian chromosomes that seem to have a significant impact on human health.We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out t
Not just a ‘royal disease’: Hemophilia’s devastating past to recent advances
Hemophilia is a rare bleeding disorder caused by a deficiency in clotting factors in the blood, which can cause permanent damage to joints and, in some cases, life threatening bleeding, both externally and internally. Today, people with hemophilia can live generally long, healthy lives, but in previous generations, the future wasn’t so bright. In fact, less than a century ago the life exp
[BONUS] Fungus farming ants and disappointing orange juice: Tiny Show and Tell Us #17
In this episode of Tiny Show and Tell Us, we cover the incredible world of fungus farming ants and how it really needs to be a Pixar movie. Then we talk about what makes fresh squeezed juice taste so much better than the mass produced processed juices you pick up in the grocery store. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.
How plants shaped our world: Rising oxygen, blocky bones, and other pivotal moments in evolution
In the summer of 2011, paleontologist and science writer Riley Black was on a mission. Walking through the Montana desert, she was on the lookout for a Tyrannosaurus rex. But that day, she wasn’t having any luck. Sitting atop a rock, she pulled out a geological hammer, sometimes called a rock pick, to dislodge a little piece and try to discern its composition. What she saw was a leaf, but
![[BONUS] 'Night soil' recycling and could viruses be the new antibiotics?: Tiny Show and Tell Us #16](https://content.production.cdn.art19.com/images/36/85/f3/5b/3685f35b-563a-44c7-b576-bbd873926dbe/a9b386c3f94229342ff3e42d077d564fceecfb30c7bcd2be6ee753ea77a539703a9d8a2b1a438e9b87b29648c832ddb8ec418dd55cc928a2a0b5b9e1ffc9267e.jpeg)
[BONUS] 'Night soil' recycling and could viruses be the new antibiotics?: Tiny Show and Tell Us #16
In this episode of Tiny Show and Tell Us, we consider if bacteriophages could become our biggest allies in the fight against antibiotic resistance. Then we cover the historical role of "night soil men" and how some sewage treatment systems today are setting the standard for sustainable management of human excrement while also making sure we don't get sick. We need your stories — they're w
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