
Probably Science
Professional comedians with so-so STEM pedigrees take you through this week in science. Incompetently. Featuring hosts Matt Kirshen, Andy Wood (and sometimes Jesse Case or Brooks Wheelan) along with a rotating cast of special guests from the worlds of comedy and science.
Episodes

Episode 613 - Dave Holmes
Writer/podcaster/host Dave Holmes (@daveholmes) returns to the show to talk with Jesse, Matt and Andy about his new Substack Cocksure, his memoir Party of One, the waning days of monoculture at MTV, Dave's excellent MTV history podcast Who Killed The Video Star?, Helen Twelvetrees, the band Rocket, Dan Taberski's Manifesto podcast, blocking out your inner cynical friend, the movie Ghost Dad, Dave'

Episode 612 - Alison Leiby
Comedian/writer Alison Leiby (@alisonleiby) joins Jesse, Andy and Matt to talk about her new memoir I'm A Lot, AI promotional scams, chronic back pain, how happiness can literally break your heart, takotsubo octopus traps, a breatkthrough in Alzheimer's-related sleep loss, plaque talk, inhaling CO2 to help with Alzheimer's, debunking the electric pangolin, giraffe math and ranking the intelligence

Episode 611 with Hannah Roeschlein
Hannah Roeschlein (@handerpumprules) joins Jesse and Matt for half the episode before the computer gods get angry, forcing the two guys to finish the show solo. But between us we talk about Filipino divers! Synthetic cells! And Hobbits and Komodo dragons! In the Patreon bonus, we get into space fires, and hear how Matt got served by a legendary astronaut and Jesse angered BBQ fans. Click here to

Episode 610 - Kirk Smith
Comedian Kirk Smith (@kirksmithcomedy) joins Jesse, Andy and Matt to talk about his books Rice Krispies with Ketchup and Movin, pools and jacuzzis, competitive eating champions, the science of fireworks, the lack of rap in the Billboard Hot 100 and Andy's upcoming Oregon tour.

Episode 609 - Ryan Conner
Comedian/author Ryan Conner (@ryanconnercomedy) returns to the show to talk with Jesse, Andy and Matt about his new memoir 12 Guys Walk Into a Kitchen, Vietnamese refugees, Tippi Hedren's nail salon legacy, British soccer fans cleaning up in the US, the worst year to be alive, 2020 vs. 1968, hipster nostalgia, stomp clap tall bikes and nuclear (not atomic) clocks.

Episode 608 - Laura Sams Jordan
Zoologist/producer/composer/podcaster Laura Sams (@lauramsams) Jordan joins Jesse, Matt and Andy to talk about fliming grizzly bears in Alaska, studying hyenas in Africa, Laura's kid-friendly wildlife podcast The Happiest Animal Show, starting a production company with your sibling, interviewing six-year-olds, Laura's inflatable basking shark, the shocking actual appearance of basking sharks, the

Episode 607 - Diana Hong
Comedian Diana Hong (@dhongcomedy) joins Jesse, Andy and Matt to discuss cat ownership, Shadow Force, Sawbones and the McElroy-iverse, Diana's golf career, outsider commemorative art, a new way to get your lithium, battery types, alkali metals reacting with water, Lithium Valley, bottle recycling in the US, Sonny Bono's Palm Springs legacy, awful bronze statues, RIP Primm (maybe), an optimal robot

Episode 606 - Charles Star
Lawyer-turned-comedian and self-professed podcast slut Charles Star (@ugarles) returns to the show to talk about his podcast No Homework, celebrity roasts, Wings album covers, bad abbreviations, contact lenses that ease depression in mice, the insect with the biggest nuts, self-recognition in beluga whales and the link between sleep duration and accelerated aging.

Episode 605 - James Frey
Comedian and former paramedic James Frey (@jamesfreycomedy) joins Andy, Jesse and Matt to talk about firefighter dreams and emergency medicine reality, James' Ventura comedy show, giving CPR in civilian life, a woman (well, women) who couldn't burp, getting fobbed off, sucker fish hiding in manta rays' butts, a quantum battery breakthrough and missing scientist conspiracy theories.

Episode 604 - Shane Mauss
Comedian Shane Mauss (@shane_mauss) returns to the show to talk about his upcoming comedy special TRIPS: The First Dose, how LSD affects blind people, misophonia's link to anxiety and depression, the goring of a matador's ass, plants 'hearing' rain coming and Shane's comedy/science podcast Here We Are.

Episode 603 - Brandie Posey
Comedian Brandie Posey (@brandazzle) returns to the show to talk with Jesse, Andy and Matt about the geography of Jersey, Brandie's label Burn This Records and her new comedy special Milk Job, Andy's other ska band, why humans can't regenerate limbs, a huge volcano refilling with magma, the dude who got both his arms reattached in 1992, whether Yellowstone is due for an eruption and Fruit Love Isl

Episode 602 - Chandler Dean
Comedian/speechwriter Chandler Dean (@chandlerjdean) joins Jesse, Andy and Matt to talk about his show Abolish Everything!, Jesse's over-the-top stuffed animal purchase, poop speed as a health indicator, the Bristol Stool Chart, medical fake poo, Jesse's obsessions with fake foods, giant stuff and really tiny stuff, Artemis II's avatar crewmates, the magic of Tiny Empath Babies, videos of Tiny Emp

Episode 601 - Amber Preston
Comedian Amber Preston (@prestonparty) returns to help Andy, Jesse and Matt celebrate the big six-oh-one and talk about Artemis II, frozen urine in space, a microbe that makes you stronger, Trump's insane handshakes, sharks testing positive for cocaine and sperm difficulties in zero-g.

Episode 600 - Katie Novotny
Comedian Katie Novotny (@katienovotnyyyyy) joins Matt and Andy to discuss her special Son of Your Dreams, whale junk, headbutting whales, the 20-year cycle of fashion, an evolved arsenic tolerance, Thai children who can see underwater and a Warsaw Poland Bros. song Andy plays on.

Episode 599 - Monica Nevi
Comedian Monica Nevi (@monicanevi) joins Andy, Jesse and Matt to talk about her special Big Stepdad Energy, what VO2 max means, esports scholarships, vasectomy rate spikes during March Madness, the effect of carbonated water on gamer performance, a bunch of human brain cells in a petri dish playing Doom, unlocking the antibacterial secrets of frogs and using frogs to keep milk from spoiling.

Episode 598 - Matthew Coe
Comedian Matthew Coe (@matthew_coe__) joins Jesse, Andy and Matt to talk about parents watching comedy, Matthew's show My Therapist Knows Your Name, Matthew's hypoplastic right heart syndrome, the closing of the foramen ovale, a Japanese study of falling cats, a robot handling potato chips, and an averted Moon asteroid close call.

Episode 597 - Jackie Kashian
Comedian Jackie Kashian (@jackiekashian) returns to the show to talk with Jesse and Matt about her new standup special Alter-Kashian, huge amounts of hydrogen inside the Earth's core, weird things yawning does in your brain and a possible universal vaccine. See Matt on tour in Seattle and Portland, and Andy on tour in Santa Barbara.

Episode 596 - Forrest Shaw
Comedian and former marine biologist Forrest Shaw (@forrestshaw) returns to the show to talk with Matt, Andy and Jesse about his new live show The Ocean Hates You, his addiction podcast I've Got A Problem, bonnethead sharks, the rise of online sports gambling, a Kalshi market about aliens, and the myth of alpha wolves.

Episode 595 - Aisha Alfa
Comedian Aisha Alfa (@aishaalfa) joins Jesse, Andy and Matt to talk about comedy in Winnipeg, Jesse's Megyn Kelly-loved Olympics tweet, the cult movie Phantom of the Paradise, Andy's family friend Olympic ice dancer, the German word for a living stork with an arrow in it, the penis injection Olympic ski jumping controversy, an amazing artificial lung feat, Jesse's artificial lung cat bed, Aisha's

Episode 594 - David Huntsberger
Comedian David Huntsberger returns to the show to talk with Matt, Jesse and Andy about his podcast Intercepts, his new platform The Endless Abyss, the lost art of sketch comedy albums, the world's worst redaction, Redactle, how dogs build their vocabularies like toddlers, Stella the talking dog, dumb dogs, breed stereotypes, Bad Will Hunting, the worst logo and name in education, longevity in meat

Episode 593 - Diya Basrai
Comedian/neuroscientist Diya Basrai (@diyabasrai) joins Jesse, Andy and Matt to talk about Moravec's Paradox, whether there's something meat-specific about intelligence, a less-pessimistic AI take, a tool-using cow, Diya's comedy special and his comedy/science live show Uncontrolled Variables.

Episode 592 - Jon Stringer
Comedian Jon Stringer (@jonjstringer) joins Andy, Jesse and Matt to talk about living in a converted rural Kansas church, the intricacies of comedy competitions and cruise ship comedy, dry ice PVC soupcan launchers, the oldest known use of poison arrows, retail blowguns and their misuse, vibe-coding a band manager, why you should stop using hydrogen peroxide on cuts, sword canes and pendulous door

Episode 591 - Imaan Hadchiti
Comedian Imaan Hadchiti (@imaanfrankhadchiti) joins Jesse, Andy and Matt to talk about Rima syndrome, the movie Tiptoes, the passing of an art legend, sniffing farts to prevent Alzheimer's, what actually causes ice to be slippery, when physical aging really kicks in and making paralyzed rats walk again in a really creepy way.

Episode 590 - Waen Shepherd
Comedian/actor/writer/composer Waen Shepherd (@waenshep) joins Andy, Jesse and Matt to talk about the new album from his alter ego Gary Le Strange, the biology of elves, the best chocolate chip cookie recipe, a runaway supermassive black hole, a lemon-shaped exoplanet and the music of Gary Wilson.

Episode 589 - Chris Duffy
Comedian/host/author Chris Duffy (@chrisiduffy) returns to the show to talk with Jesse, Andy and Matt about his new book Humor Me: How Laughing More Can Make You Present, Creative, Connected, and Happy, his radio show/podcast You're The Expert, his TED podcast How To Be a Better Human, the unintentionally phallic Covid-era Terry Crews video Chris worked on with Matt and Andy, prescribing standup t

Episode 588 - Buddy Fitzpatrick
Comedian Buddy Fitzpatrick (@buddycomic) joins Andy, Matt and Jesse to talk about Batman's effect on subway chivalry, the rooms of Madonna Inn, ladyfingers, manmade fire from 350,000 years earlier than previously thought, monogamy across the animal kingdom and an insane chain of rabies transmission via organ transplantation.

Episode 587 - Adam Burke
Comedian Adam Burke (@atpburke) joins Andy, Jesse and Matt to talk about Adam's new comedy special Unamerican, debunking the Stanford Prison Experiment, classic '80s Arnold movies, Matt and Jesse performing together in Nashville, the preacher who shot an escaped lab monkey, AIs that believe themselves to be more rational than humans, 3D printing with a mosquito proboscis, Andy's upcoming orchestra

Episode 586 - Ophira Eisenberg
Comedian/writer/NPR host Ophira Eisenberg (@ophirae) joins Andy, Jesse and Matt to talk about her podcast Parenting Is a Joke, her upcoming special produced by Lewis Black, the effect of venting on anger, a rage room show Andy worked on, why you should leave uncontacted tribes alone, the wombat-thief influencer and why you should speak up to seagulls.

Episode 585 - Jeff Zenisek
Comedian Jess Zenisek (@jeffzenisek) joins Andy, Jesse and Matt to talk about tennis, homophobic sports stereotypes, Jesse's new ski persona, Mr. Wizard, Jeff's hair care regimen, a tiny tyrannosaur, a better rock-paper-scissors strategy, gray hair's relationship to cancer, the worst music to play during sex and the banger Parked By The Lake.

Episode 584 - Drew Droege
Comedian/playwright Drew Droege (@drew_droege) joins Matt, Jesse and Andy to talk about his new off-Broadway play Messy White Gays, X-ray NBA poker fraud and why birds sing after a solar eclipse.

Episode 583 - Mehran Khaghani
Wonderful NY comic Mehran Khagani (@themehran) joins Jesse and Matt to talk about escaping from Iran, working at the Harvard School of Public Health, hyrax butt drag fossil marks, Canadian heart transplants and the most pristine star in the universe! In the patreon bonus we get into penguin micronaps. Click here to support Probably Science via Patreon

Episode 582 - Jen Kober
Comedian/actor Jen Kober (@jenkober) joins Andy, Jesse and Matt to talk about comedy in Louisiana, Oktoberfest, buxom wenches, the connection between fish buttholes and fingers, a koala chlamydia vaccine, Jesse's newfound raccoon fame, light-powered gears that fit inside a strand of hair and Jen's membership in the Star Wars canon.

Episode 581 - NASA Exoplanet Science Ambassador Anjali Tripathi
NASA astrophysicist and JPL Exoplanet Science Ambassador Anjali Tripathi joins Andy, Jesse and Matt to talk about exoplanets and the different ways of finding them including radial velocity, transits and gravitational microlensing, the challenges of studying planetary atmospheres, why telescopes are built in deserts or in space, Anjali's time at the White House Office of Science and Technology Pol

Episode 580 - Michelle Murphy
Comedian Michelle Murphy (@meeshoffleash) joins Andy, Matt and Jesse to talk about playing tennis for Grinnell, the Enhanced Games, celebrities trying their hands at winter sports, Jesse's accidental mermaid book purchase and the Dr. Seuss book he was aiming for, Burning Man missionaries, LSD to fight anxiety and surprisingly not too uncommon iridescent mammals.

Episode 579 - Ken Reid
Comedian Ken Reid (@kennethwreid) joins Jesse, Matt and Andy to talk about growing up a child of television, mud wrestling, Ken's podcast TV Guidance Counselor, an HIV prevention breakthrough, the insanity of Movie 43, the human washing machine no one asked for, blasting plastic waste with a plasma torch, Doja Cat's nod to Max Headroom, Ladies and Gentlemen, The Fabulous Stains, the reason plastic

Episode 578 - Ryan O'Flanagan
Comedian Ryan O'Flanagan (@ryanoflan) joins Matt, Jesse and Andy to talk about Ryan and Andy's chance encounter in a bar in Leadville, Married With Children tattoos, neanderthals and homo sapiens interbreeding, a novel telescope shape to help search for exoplanets, an insane impression of a neanderthal voice and Ryan's podcast Laser Show.

Episode 577 - Myq Kaplan
Comedian Myq Kaplan (@myqkaplan) returns to the show to talk to Andy, Jesse and Matt about growing out his eyebrows during the pandemic, babies distinguishing Ps from Bs, linguistics, sign language variations, standups aping Shane Gillis, the Mr. Beast voice, birds' preference for crapping in the air, strong link versus weak link problems, Ryan North, whether you should pay for bad art, what seque

Episode 576 with Macey Isaacs!
Comedian and host of the SSRI'M OK podcast Macey Isaacs joins the gang to talk about a meteorite that's older than our planet! AI and attachment theory! And some more AI nonsense before Andy's connection quit in a fury! In the Patreon bonus we find out why living near the ocean extends your life. Follow Macey on instagram and check out her podcast, and her Don't Tell special when it drops! Click

Episode 575 - Matt Parker
Comedian/mathematician/YouTuber/author Matt Parker (@standupmaths) joins Jesse, Andy and Matt to talk about his new book Love Triangle: How Trigonometry Shapes the World, his podcast A Problem Squared, his Edinburgh Fringe show Getting Triggy With It, Mathstodon, a hawk that uses traffic patterns to target prey, desire paths, Earth's leaking core, the Gibeon meteor, Matt's comedy tour dates and An

Episode 574 - Josh Gondelman
Comedian Josh Gondelman (@joshgondelman) joins Andy and Matt to talk about his new special Positive Reinforcement, his newsletter, his wife Maris Kreizman's new book of essays, the geek/nerd/dweeb/dork Venn diagram, Nancy Kerrigan and Chris Farley, a new ass-grass fad among chimps, ass/gas/grass bumper stickers, neanderthals eating maggots and rotten meat, how surprisingly warm Uranus is and Tylen

Episode 573 - Kai Humphries
Comedian Kai Humphries (@kaihumphries) joins Matt, Andy and Jesse to talk about his new special Gallivanting, the passing of Hulk Hogan, superheating solid gold, the Air Bud cinematic universe and an enormous 80,000-year-old blob in Utah.

Episode 572 - Eric Rocha
Comedian Eric Rocha (@ericrochacomedy) joins Andy, Jesse and Matt to talk about competing namesakes, fezzes, last suppers, Jesse's macronutrient gas, sleep hygiene, comedy on airplanes, what would happen if you threw a paper airplane from the ISS, a neanderthal fat factory, Matt's standup tour and Andy's Colorado ska tour.

Episode 571 - Bryan Cook
Comedian and Jimmy Kimmel Live! writer Bryan Cook (@bryancooking) returns to the show for a technical difficulty-laden episode in which Jesse and Andy talk with Matt while he's on a cruise ship, covering topics including comedy on a boat, candlepin bowling, a new interstellar object, crypto failures, Anthropic's Claude having an identity crisis, the Sean Connery classic Zardoz, an AI band with way

Episode 570 - Matt, Jesse and Andy
The gang's back together again to talk about how your pets alter your immune system, a plan to bomb an island full of invasive mice, why the Pentagon wants you to believe in UFOs and a rare post-orgasm illness that causes days of flu-like symptoms.

Episode 569 - JT Habersaat
Comedian and author of new book Doing Time: Comedians Talk About Standup JT Habersaat (jtcomedy.com) to talk about the other books on Jawbone Press! Making bespoke action figures! Changing your brainwaves to not feel pain! Infrared contact lenses for night vision! Other contact lenses to cheat at poker! How joke magazine x-ray specs "work"! A shapeshifting octopus! And whether the Loch Ness M

Episode 568 - Tom Rhodes
Globetrotting headliner Tom Rhodes (tomrhodes.net) has a new special, The Ripest Zebras, available on his website. He joins Jesse and Matt to talk about growing up in NASA's backyard! The chair challenge! Wasps having surprisingly good memories! While herrings might not! Tom's hummingbird facts! Plus how to drop an egg! And push straws through potatoes! In the Patreon bonus we hear about an upda

Episode 567 - Ron Placone
Comedian and filmmaker Ron Placone (@ronplacone) joins Andy, Jesse and Matt to talk about his new movie Left at Wall, the guy who let venomous snakes bite him hundreds of times for science (kind of), a color no one had seen until now, retinitis pigmentosa and turning lead into gold.

Episode 566 - Amy Silverberg
Comedian, writer and author of upcoming novel "First Time, Long Time" Amy Silverberg (@amysilverberg) joins the gang to talk about Andy's Irish landscape spotting! The optimal amount of bra bounce! Andy's Iberian adventures! Lions biting gladiators! Men fighting gorillas! And which glasses to wear to avoid the fight yourself! In the Patreon bonus we talk about lucid dreaming and a new state of

Episode 565 - Tony Camin
Great stand-up and co-creator of the Marijuana-Logues Tony Camin (@tony.camin) joins Jesse and Matt to talk about crows' geometry skills! Tony helping one of the fathers of decision analysis! Why seals don't drown! Unlikely animal friends! And whether your month of conception shapes your body! Tony's new album, An Ass Pocket of Whimsy will come out on Stand-Up! Records and you can find him at t

Episode 564 - Samantha Hale
Comedian and Horror Nerd Samantha Hale (@thesamanthahale) joins Jesse and Matt to talk about: A layer of life deep below us! The not actually back from extinction dire wolves! The Earth's mysterious pulsations! and Reagan's obsession with the Titanic! In the Patreon bonus we talk about bending sounds. Click here to support Probably Science via Patreon Click here to subscribe in Apple Podcasts

Episode 563 - Live from Perth with Wil Anderson and Robyn Perkins
Friend of the show Wil Anderson (@officialwilanderson) joins Matt live in Perth along with marine biologist-turned-comedian Robyn Perkins (@robynhperkins) to talk all things coral, nudibranchs, poisonous sea creatures and surprising things to do with dry ice and mouths.

Episode 562 - Shawn Carlow
Writer/comedian Shawn Carlow (@shawncarlow) joins Jesse, Andy and Matt to talk about his new book People of the Titanic: 30 Tales of Extra-Doomed Souls Who Sailed on The Ship of Dreams, mouse-to-mouse resuscitation, what your poop schedule says about your health and physicists creating a supersolid out of light.

Episode 561 - Live from Perth with Ross Noble, Kirsty Webeck and Paul Savage
Live from Perth, Matt is joined by Ross Noble, Kirsty Webeck and Paul Savage to talk about if you can cook a chicken by throwing ice cubes at it, dolphins communicating with pee streams, dormant volcanoes that aren't that dormant and astronauts' eyesight.

Episode 560 - James P. Connolly
Comedian James P. Connolly (@jamespconnolly) joins Andy, Jesse and Matt on location from the SLO Comedy Festival to talk about centaurs and minotaurs, plum grenades, forcing comedy on bar patrons, the asteroid that was at one point maybe going to hit us, the return of measles, Jesse's update on the state of Nashville, overly clean living conditions in space and microscopic obelisks in your gut.

Episode 559 - Aidan Jones
Comedian Aidan Jones (@aidanjonescomedy) joins Matt, Andy and Jesse to talk about his musical comedy show Chopin's Nocturne, returning to classical music after a long break, piano tuning dorkery, doing Mozart covers, 66 million-year-old fish vomit, racy Mozart compositions, drawing dinosaurs with Zhao Chuang, talking dinosaurs with same and jerking it during a volcanic eruption.

Episode 558 - Alice Fraser
Comedian Alice Fraser (@aliterative) returns to the show to talk with Jesse, Andy and Matt about Jesse's mistimed melatonin, Alice's new book A Passion for Passion: A Delirious Love Letter to Romance, Hot Frosty, Matt's upcoming Australia shows, how ants can beat humans at cooperation, increasingly dumb reality dating shows, Andy's Naked Attraction obsession, science lectures on Pornhub, burial si

Episode 557 - Mary Lynn Rajskub
(Note: This episode was recorded before the Los Angeles fires) Comedian/actor Mary Lynn Rajskub (@marylynnrajskub) joins Jesse, Andy and Matt to talk about filming her upcoming show North of North in Nunavut, her new standup special Road Gig, how Roman air pollution lowered the IQ of Europe, long eggs, the thick ice of Europa, Matt's upcoming Australia shows and Andy's upcoming Arizona ones.

Episode 556 - Laura Hayden
Comedian and physical therapist Laura Hayden (@LauraHaydenFun) joins Jesse, Andy and Matt to talk about her penile pictorial book What About Dick, a decrease in average body temperature, sciatica advice, the benefits of pooping before you exercise, Matt's upcoming Australia tour and Andy's upcoming Warsaw Poland Bros gigs.

Episode 555 - Forrest Shaw
Comedian Forrest Shaw (@forrestshaw) returns to the show to talk about stalking manatees with police helicopters, gambling addiction, his upcoming podcast I've Got a Problem, survival of the wittiest, a lost branch of humanity's family tree, Matt's upcoming comedy shows in Eureka and Medford and Andy's upcoming Warsaw Poland Bros shows in Santa Barbara and Los Olivos.

Episode 554 - Matthew Broussard
Comedian Matthew Broussard (@mondaypunday) returns to the show to chat with Jesse, Andy and Matt about Matthew's new special Hyperbolic, exaggerated accents, the CEO shooter, cyborg beetles, a quantum computing milestone, gray goo, online security in a post-quantum world, elliptic curves, conic sections, Fermat's Enigma and a super old bird mother.

Episode 553 - Becky Braunstein
Comedian Becky Braunstein (@beckyfromalaska) joins Andy, Jesse and Matt to talk about growing up Jewish in Alaska, eruv rules and topology, orcas bringing back the salmon hat fad, the dangers of squeezing limes in bright sunlight, and tiny vodka-propelled robots.

Episode 552 - Laura Kightlinger
Comedian/writer/actress Laura Kightlinger (@KingKightlinger) joins Matt, Jesse and Andy to talk about spontaneous human combustion, Bourbon Room comedy shows in Hollywood, the story behind Andy's various bands, the Uranus story we don't want to cover, how one atom can change a parrot's color, blurb machine Peter Travers, peacock spiders, a blue whale that's been leaking oil for 26 years and a flu

Episode 551 - James Lamont
Screenwriter James Lamont joins Matt, Jesse and Andy to talk about writing the upcoming Paddington in Peru, alcohol detox champion hornets, Shatner's double SPATS, memory not being confined to the brain, Jesse getting checked in on by local kids and Matt's oath to take up arms for the United States.

Episode 550 - Benny Blue
Comedian Benny Blue (@bennyblueeyes) joins Jesse, Andy and Matt to talk about brat summer transitioning into the fall of civilization, Benny's new special Live From My Mother's Funeral, Benny and Andy's Blue Lake connection, Anarchist Cookbook adolescent shenanigans, why humans are the perfect size for speed, Matt and Andy's show with the 2022-iest name ever, the best mural ever painted and its pa

Episode 549 - Brooks Wheelan
Comedian and former Probably Science cohost Brooks Wheelan (@brookswheelan) joins Jesse and Andy to talk about his new special Alive In Alaska, Tony Hinchcliffe entering the election arena, cats beating babies at word association, Don't Wake Daddy, snake talk just for Brooks, the Teddy Roosevelt biography The River of Doubt, Chuck Klosterman's The Nineties, the ever-changing landscape of standup a

Episode 548 - Jeffrey Jay
Comedian Jeffrey Jay (@heyjeffreyjay) joins Matt, Jesse and Andy to discuss UnCertified Fresh, the Matt Walsh-iverse of awful movies, Earth gaining a second moon, the orbital path of that object, an octopus that punches fish to make them help it hunt and choceted EEG caps for cats.

Episode 547 - DJ Qualls and Kelly Blackheart
DJ Qualls (@TheOnlyDJQualls) and Kelly Blackheart (@kellyblackheart) of the Locked & Probably Loaded podcast join Matt and Jesse to talk about DJ's upcoming movie Carved, Nashville dive bars, the Ark Encounter, the Ig Nobel prize for butt-breathing, extreme aging, re-creating Mars in a lab and resurrecting the woolly mammoth.

Episode 546 - Maronzio Vance
Comedian Maronzio Vance (@maronziovance) joins Andy, Matt and Jesse to talk about Andy's upcoming ska festival and Oktoberfest polka band gigs, Taipei's innovative trash system, dating Prince-obsessed women, dogs' incredible ability to remember the names of toys, the gut-first path of Parkinson's and comedy's legendary Tribble runs.

Episode 545 - Helen Hong
Comedian/actress/podcaster Helen Hong (@funnyhelenhong) joins Matt and Andy to talk about peeing in pools and reservoirs, male stripper shows, Helen's excellent quiz podcast Go Fact Yourself, pre-Darth Vader David Prowse PSAs, the dye in Doritos that can make mice transparent, a SpaceX rocket punching a hole in the ionosphere, mailing poo in a box and making pyrex invisible with vegetable oil.

Episode 544 - Sam Pasternack
Writer/producer Sam Pasternack (@sampasternack) returns to the podcast to talk with Matt, Andy and Jesse about awful bar trivia, Sam's new book "Walker," the history of pedestrianism, Land's End to John o' Groats, Andy's Burning Man updates, the dilemma of trombone utility and using massive python meals to help develop new human heart medicines.

Episode 543 - Frank Conniff
Mystery Science Theater alum, comedian and author Frank Conniff (@FrankConniff) joins the crew to talk about his new audiobook Dark Apnea. Plus horoscope doubts! Carl Sagan predicting the future! And where dinosaur killing asteroids came from! In the patreon bonus ep we talk about saving the banana from extinction. Sign up here!

Episode 542 - Mark Cohen
Comedian Mark Cohen (@mark_coco_cohen) joins Jesse, Andy and Matt to discuss the two aging bursts humans experience, restoring Tonka trucks, weaning crocodiles off of cane toads, Mark's video game creations, using slime mold to help map dark matter, and stock photo artists who play Lawn Mowing Simulator. and Mark's possible record-breaking stint at The Comedy Cellar in Las Vegas.

Episode 541 - Isak Allen
Neuroscientist-turned-comedian Isak Allen (@isakallen) joins Matt, Jesse and Andy to talk about smashing flies, using fMRI to study brain activity as it relates to music and comedy, tonal languages, the Dong Song, Neuralink, dystopian futures and Isak's new Dry Bar special Culturally Unavailable.

Episode 540 - The Sports Gene with David Epstein and Paul Morrissey (re-release)
We've got just the prescription for everyone out there with Olympic fever: A re-release of a 2013 episode in which Matt and Andy interview David Epstein, a Sports Illustrated journalist and the author of the outstanding book The Sports Gene, along with college basketball player-turned-comedian Paul Morrissey, to discuss the field of sports genetics research and try to get to the bottom of how elit

Episode 539 - Cathy Ladman
Comedy legend Cathy Ladman (@cathyladman1) joins Jesse, Andy and Matt to talk about creepy Foundation for a Better Life billboards, cancer battles, 1970s acid, the CrowdStrike software crash, how propofol tips your brain into chaos, the merits of comedy classes, Brazilian cocaine sharks and Cathy's September 7th Vegas show.

Episode 538 - David Brown
Producer David Brown joins Jesse, Matt and Andy to talk about creating entertaining science programming, the new Peacock show The Hungry Games: Alaska's Big Bear Challenge that David produced, Rhys Darby narrated and Matt and Andy worked on, the Emmy-winning pop-science show Could You Survive The Movies?, Andy's Top Gun cameo, Fat Bear Week, Goro's pecs, a south-of-the-border Orson Welles experien

Episode 537 - Todd Barry
Comedian Todd Barry (@toddbarry) joins Matt, Andy and Jesse to talk about his new special Domestic Shorthair, an FDA ban of a citrus soda ingredient, ginger ale vs. ginger beer, the quackery of Dr. Idz, new images of an asteroid that just whizzed by Earth, Jesse's air force base food poisoning story, whether toxoplasmosis causes crazy cat lady syndrome and Jackson Galaxy's Cat Camp.

Episode 536 - Sid Singh
Comedian Sid Singh (@mrsidsingh) joins Andy, Jesse and Matt to talk about being a Brexit and Biden bellwether, Mozart the millenial, weird tunings, 432 Hz bullshit, old-ass Washington cherries, SPATS updates, a clever way to curb rhino horn poaching, meat rice, debunking Novi's etymology and ant surgeons.

Episode 535 - Jordan Morris
Writer/podcaster Jordan Morris (@Jordan_Morris) returns to the show to talk with Matt, Jesse and Andy about his upcoming graphic novel Youth Group, the YA genre, hawk tuah, breakdancing in the Olympics, elephants calling each other by name, wartime magicians, GPT-4 passing the Turing Test, using AI to cancel customer anger, a new stab at AI alignment and creating plasma fireballs in the lab.

Episode 534 - Bobcat Goldthwait, Rhys Darby, Dr. Farah Alibay and Natalia Reagan
Matt and Andy host a live installment of the podcast from To 29 and Beyond in Twentynine Palms featuring guests Bobcat Goldthwait, Rhys Darby, Dr. Farah Alibay and Natalia Reagan, digging into topics including indoor rocketry, opening for Nirvana, projectile bibles, the Cryptid Factor podcast, Bobcat's Bigfoot movie, 10 Million Dollar Bigfoot Bounty, Robin Williams and Koko the gorilla, Mars lande
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