Revolution Health Radio
Revolution Health Radio debunks mainstream myths on nutrition and health and delivers cutting-edge, yet practical information on how to prevent and reverse disease naturally. This show is brought to you by Chris Kresser, health detective and creator of chriskresser.com.
Episodes
RHR: Do Vegetarian and Vegan Diets Get Riskier as You Age? What Two New Studies Reveal
In this episode of Revolution Health Radio, Chris breaks down two new studies of older adults that examine protein and micronutrient intake on plant-based diets. The findings raise important questions about protein quality, B12, calcium, zinc, vitamin D, and other nutrients—especially as aging increases protein needs and can reduce nutrient absorption. He also explores whether plant-based diets ac
RHR: The Melatonin Problem
In this episode of Revolution Health Radio, Chris takes a nuanced look at melatonin and challenges the idea that because it is a naturally occurring hormone, it is automatically safe for routine, long-term use. He explains melatonin’s primary role as a circadian signal rather than a conventional sedative, explores concerns surrounding prolonged use and supplement quality, and examines recent resea
RHR: The Hidden Harms of Ultra-Processed Foods
In this episode of Revolution Health Radio, Chris takes a deep dive into the latest research on ultra-processed foods, their potential impact on health, what distinguishes ultra-processed foods from minimally-processed and traditionally-processed foods, and why a Nutrition Facts label may not capture everything that matters about a food. He examines research linking higher ultra-processed food con
RHR: Can You Reverse Your Biological Age?
In this episode of Revolution Health Radio, Chris Kresser explores what biological age really means and examines the research behind today's most popular longevity claims. He explains how epigenetic clocks and DNA methylation are used to estimate biological aging, why these tests may be less precise for individuals than they appear, and what studies like the CALERIE trial tell us about slowing the
RHR: My Top 3 Ingredients for Joint Health, Mobility, and Cartilage Repair
In this episode of Revolution Health Radio, Chris breaks down the science behind joint pain, osteoarthritis, and cartilage degeneration while challenging one of the most common assumptions about joint health—that glucosamine and chondroitin are the gold standard for protecting cartilage and relieving pain. He explains why current clinical evidence no longer supports those supplements as the best o
RHR: Why Microglia Are the Key to Brain Health, with Dr. David Perlmutter
In this episode of Revolution Health Radio, Chris Kresser sits down with renowned neurologist and bestselling author Dr. David Perlmutter to discuss the emerging science of microglia—the brain's immune cells—and why they may hold the key to preventing cognitive decline and Alzheimer's disease. Drawing from his new book, Brain Defenders, Dr. Perlmutter explains how lifestyle factors such as nutriti
RHR: Your Mouth is Talking To Your Brain—And You Should Be Listening
What if one of the most overlooked risk factors for cognitive decline isn’t in the brain—but in the mouth? In this episode of Revolution Health Radio, Chris Kresser explores the emerging science linking oral health to brain health. He examines how chronic gum disease may contribute to cognitive decline, Alzheimer’s disease, and Parkinson’s disease through systemic inflammation, direct bacterial mi
RHR: Fibermaxxing: Why the Internet’s Hottest Gut Health Trend Gets It Half Right
In this episode of Revolution Health Radio, Chris takes a deep dive into the science of dietary fiber, fiber supplements, and microbiome health. He explains why the benefits seen in high-fiber diets may come from whole foods rather than isolated fiber supplements, and why aggressively increasing fiber intake can worsen bloating, gas, and gut dysfunction for some people. He explores the latest rese
RHR: Revisiting the Gut-Immune Axis
The gut-immune axis is one of the most important and most overlooked systems in human health. In this episode of Revolution Health Radio, Chris explains how the gut microbiome, intestinal barrier, and immune system work together to regulate inflammation and protect against disease. Learn how disruptions in gut health, driven by ultra-processed foods, environmental toxins, antibiotics, and chronic
RHR: Beyond the Headlines: A Functional Medicine Approach to Microplastics
In this episode of Revolution Health Radio, Chris unpacks the latest science on microplastics. He explores groundbreaking studies linking microplastic accumulation to increased risk of cardiovascular disease, inflammation, and potential neurological impacts, while clarifying what we know—and what we don’t. You’ll learn how microplastics enter the body, why nanoplastics pose a greater risk, and how
RHR: The Sleep Optimization Trap: Are You Tracking Yourself Into Worse Sleep?
In this episode of Revolution Health Radio, Chris Kresser explores the growing phenomenon of orthosomnia, a condition driven by the obsessive pursuit of perfect sleep metrics. While devices like the Oura Ring, Whoop, and Apple Watch offer valuable insights, they can also increase anxiety and disrupt the very sleep they aim to improve. Chris breaks down the science behind sleep anxiety, including t
RHR: The GLP-1 Blind Spot: What Ozempic Won’t Do for Your Metabolic Health
In this episode of Revolution Health Radio, Chris explores the science behind GLP-1 medications, including their powerful effects on appetite, weight loss, and cardiometabolic risk. He also uncovers the critical blind spots in the current conversation, including new research on long-term side effects, nutrient deficiencies, muscle loss, and the high rate of weight regain after discontinuation. You
RHR: Shaking Up the Salt Myth
For decades, public health guidelines have warned that reducing sodium intake is essential for preventing high blood pressure and cardiovascular disease. But a closer look at the scientific evidence reveals a far more complex story. In this episode of Revolution Health Radio, Chris explores the history behind the low-sodium movement and examines the research that shaped modern dietary guidelines.
RHR: Mouth Taping: Beyond the Hype—What the Science Really Says
In this episode of Revolution Health Radio, Chris Kresser explores the viral trend of mouth taping and explains why the reality is more complex than the hype. While nasal breathing offers clear physiological advantages such as improved oxygen delivery, air filtration, and reduced airway resistance, the current research on mouth taping itself is limited and mixed. Chris breaks down findings from a
RHR: Erythritol: The ‘Safe’ Sweetener That’s Anything But
Erythritol, a popular sweetener found in countless sugar-free and keto products, has long been considered a safe alternative to sugar. This episode of Revolution Health Radio examines emerging research that challenges that assumption. Chris explains how erythritol promotes blood clotting, impairs blood vessel function, increases oxidative stress, and interferes with the body’s ability to dissolve
RHR: Preserving Cognitive Function As You Age, with Tommy Wood
In this episode of Revolution Health Radio, Chris Kresser is joined by neuroscientist and physician Dr. Tommy Wood to explore how cognitive function can be preserved—and even enhanced—as we age. Dr. Wood challenges outdated ideas about inevitable cognitive decline and reframes dementia as a largely preventable, multifactorial condition. The conversation covers the historical roots of Alzheimer’s d
RHR: New Study Challenges the Plant-Based Longevity Myth
In this episode of Revolution Health Radio, Chris breaks down a new large-scale study challenging the popular belief that plant-based diets promote longevity. The findings reveal that vegetarians—especially vegans—were significantly less likely to reach age 100 compared to omnivores. Chris explores the biological reasons behind these findings, emphasizing the importance of high-quality protein and
RHR: Beyond the Gut: The Microbiome’s Role in Sleep, Energy, and Longevity, with Dr. Zain Kassam
In this episode of Revolution Health Radio, Chris sits down with gastroenterologist and microbiome researcher Dr. Zain Kassam to explore the rapidly evolving science of the microbiome and its profound impact on sleep, circadian rhythm, cognitive performance, stress resilience, immune balance, and longevity. From groundbreaking research on microbiome diversity and sleep quality to emerging innovati
RHR: The Gut-Brain Connection: How Your Microbiome Affects Your Mental Health
Depression and anxiety are often treated as chemical imbalances in the brain—but what if the real problem starts in the gut? In this episode of Revolution Health Radio, we dive deep into the gut–brain connection and the growing body of research linking gut inflammation, microbiome imbalance, and mood disorders. You’ll learn how inflammatory cytokines contribute to depression, why butyrate is emerg
RHR: Vitamin D: Why a Personalized Approach Is Best
In this episode of Revolution Health Radio, Chris Kresser explains why vitamin D supplementation should never be one-size-fits-all. Drawing on new research—including a groundbreaking study on magnesium’s regulatory role—Chris explores how genetics, ethnicity, body weight, age, health status, sun exposure, and nutrient cofactors all shape an individual’s vitamin D needs. He outlines optimal testing
RHR: Cold Exposure: Why Sustained Beats Extreme
Cold plunges and ice baths dominate social media, but do they really deliver the best metabolic benefits? In this episode of Revolution Health Radio, Chris Kresser challenges the “colder is better” narrative and explores what the science actually shows about cold exposure. Drawing on clinical research, he explains how brown adipose tissue works, why sustained mild cold exposure activates it more e
RHR: Why Your Sleep Schedule Matters As Much As Duration
In this episode of Revolution Health Radio, Chris challenges the conventional focus on sleep duration and makes the case that sleep timing and circadian alignment matter just as much—if not more—than total hours slept. Drawing on new research, he explains how circadian disruption underlies poor sleep quality, chronic fatigue, and a wide range of mental health conditions, even in people who appear
RHR: Menopause Brain Fog—What’s Really Happening (and How To Fix It)
In this episode of Revolution Health Radio, Chris examines research confirming that menopause-related brain fog is real, measurable, and reversible. He explains how gray and white matter changes, blood-flow disruption, inflammation, and declining estrogen impact cognitive function during perimenopause and menopause. He also highlights the critical role of the gut microbiome in regulating estrogen
RHR: Seed Oils and Colon Cancer – What the New Research Really Shows
Seed oils have become one of the most controversial topics in nutrition, especially after a 2024 University of South Florida study linked high omega-6 levels with inflammation in colon tumors. In this episode of Revolution Health Radio, Chris takes a deep, evidence-based look at what the study actually means — and what it doesn’t. You’ll learn the crucial difference between naturally occurring ome
RHR: The Longevity Trap: Why Chasing Anti-Aging May Be Aging You
In this episode, Chris explains why obsession with anti-aging hacks may actually undermine our long-term health. He examines the common longevity traps people fall into, which foundational habits truly extend lifespan and health span, and outlines a simple framework for prioritizing what really works. If you’re overwhelmed by conflicting longevity advice, this episode brings clarity, realism, and
RHR: The Link Between Metabolic Health and Mental Well-Being, with Dr. Matt Bernstein
In this episode of Revolution Health Radio, Chris welcomes psychiatrist Dr. Matt Bernstein to explore the emerging field of metabolic psychiatry, the science linking brain energy metabolism to mental health. They discuss how conditions like depression, bipolar disorder, schizophrenia, and anxiety often share a root cause in impaired brain energy production, and how ketogenic therapy can restore ba
RHR: From Wired & Tired to Calm & Clear: My Top Nutrients for Mood, Focus, and Sleep
In this episode of Revolution Health Radio, Chris explores natural solutions for one of today’s most pressing challenges: chronic stress, anxiety, and poor sleep. He shares his top five nutrients for restoring calm and focus (saffron, L-theanine, lemon balm, holy basil, and ashwagandha), revealing how each supports the brain and body’s ability to relax, recharge, and build resilience. Drawing from
RHR: The Science Behind Oral Inflammation, with Dr. William Levine
In this episode of Revolution Health Radio, Chris welcomes board-certified periodontist Dr. William Levine to discuss the overlooked role of gum health in systemic disease. They unpack how oral bacteria and chronic inflammation contribute to conditions like heart disease, dementia, autoimmune disorders, and pregnancy complications, and why periodontal health is as critical as diet and lifestyle in
RHR: Beauty From Within – Why Radiant Skin, Hair, and Nails Start Inside
In this episode of Revolution Health Radio, we dive deep into the topic of beauty from within, exploring why radiant skin, hair, and nails truly start from the inside. Chris discusses how internal factors such as gut function, nutrient status, inflammation, blood sugar regulation, hormonal balance, and stress management are foundational to external beauty. He explains the science behind the gut-br
RHR: Mold, Indoor Air Quality, and Clean Breathing, with Michael Rubino
In this episode of Revolution Health Radio, Chris Kresser welcomes environmental wellness expert Michael Rubino for an in-depth conversation on the hidden health risks of indoor air pollution. They delve into why mold-related illness is more common than most people realize, how traditional mold testing methods often fail, and why household dust holds the key to understanding environmental exposure
RHR: The Nourishment Table, with Frederic Leroy
In this episode of Revolution Health Radio, Chris Kresser welcomes food scientist and advocate for regenerative agriculture Dr. Frederic Leroy to discuss his groundbreaking work on the Nourishment Table, a new framework for assessing dietary adequacy. They explore why conventional dietary guidelines fail, how nutrient density and food processing deeply influence human health, and the evolutionary
RHR: Rediscovering Health, Nature, and Purpose-Driven Business, with Seth Spears
In this episode of Revolution Health Radio, Chris Kresser welcomes entrepreneur and strategist Seth Spears for a wide-ranging conversation on health, resilience, and building businesses with purpose. They explore the origins of Seth’s wellness-focused companies, including Wellnesse and Rewild Gear, and how they challenge conventional thinking in personal care and outdoor lifestyle. Seth shares ins
RHR: How to Sharpen and Protect Your Mind for a Lifetime, with Dale Bredesen
In this episode of Revolution Health Radio, Chris welcomes renowned neurologist Dr. Dale Bredesen back to the show for an insightful conversation about protecting and enhancing cognitive health throughout your lifetime. They discuss groundbreaking advances in Alzheimer's prevention and early detection, explore the latest diagnostic tools and assessment techniques, and review compelling evidence fr
RHR: Everything You Need to Know About Collagen
In this episode of Revolution Health Radio, Chris Kresser dives deep into the fascinating world of collagen, the most abundant protein in the human body. He explores collagen's wide-ranging benefits—from supporting vibrant skin, healthy hair, and strong nails, to improving joint health, muscle recovery, gut integrity, and sleep quality. Chris breaks down the science behind collagen supplementation
RHR: Exploring Peak Health and Fitness, with Mark Sisson
In this episode of Revolution Health Radio, Chris Kresser talks with Mark Sisson, author of Born to Walk and renowned figure in the ancestral health space, about rethinking our approach to fitness. They challenge the conventional wisdom of chronic cardio and explore the myriad benefits of walking as a foundational movement practice. Mark shares his insights on how modern footwear and a misundersta
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