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ResusX:Podcast

ResusX:Podcast

Haney Mallemat 165 Episodes Feb 13, 2026

Welcome to the ResusX:Podcast. Each episode features an amazing talk from the ResusX conference. This is a podcast dedicated to your sickest patients, and it's all FOAMed. For more great content, including our monthly grand rounds, newsletter, and more go to www.ResusX.com now.

Episodes

Cytokine storm in acute respiratory distress syndrome
Cytokine storm in acute respiratory distress syndrome Feb 13, 2026 884 Is the "Cytokine Storm" the Real Killer in ARDS? When a localized lung injury spirals into a systemic catastrophe, we call it a cytokine storm—but are we actually any closer to stopping it, or are we just watching the rain? This deep-dive review, published in the Journal of Intensive Medicine, synthesizes decades of mechanistic research and clinical trials to map how dysregulated immune p
Diuretic resistance in cardiorenal syndrome: mechanisms, monitoring and phenotype-tailored management
Diuretic resistance in cardiorenal syndrome: mechanisms, monitoring and phenotype-tailored management Feb 4, 2026 1098 Can we break the cycle of Diuretic Resistance? What do you do when the "gold standard" treatment for your congested patient simply stops working? Diuretic resistance (DR) affects up to one-third of patients with heart failure, turning a routine clinical task into a high-stakes battle against prolonged hospitalization and mortality. In this episode, we dive into a comprehensive narrative r
Efficacy and safety of anticoagulant therapy in sepsis: A systematic review and meta-analysis
Efficacy and safety of anticoagulant therapy in sepsis: A systematic review and meta-analysis Jan 29, 2026 1083 Sepsis and Coagulation: Is It Time to Put the Heparin Away? Is "thinning the blood" the missing piece in the sepsis puzzle, or just a recipe for disaster? Sepsis triggers a deadly cascade of inflammation and clotting, yet the debate over therapeutic anticoagulation has left ICU clinicians caught between the potential for organ salvage and the perilous risk of hemorrhage. In this episode,
The Resus Recap: Hypoglycemia
The Resus Recap: Hypoglycemia Jan 25, 2026 482 Some random musings post shift
Effectiveness of noninvasive ventilation for preoxygenation in emergency intubation: a systematic review and meta-analysis
Effectiveness of noninvasive ventilation for preoxygenation in emergency intubation: a systematic review and meta-analysis Jan 22, 2026 953 Is it time to retire the Bag-Valve-Mask for preoxygenation? Emergency intubation carries a notorious risk of life-threatening hypoxemia, yet the debate on the safest way to build an oxygen reserve continues .  In this episode, we unpack a 2026 systematic review and meta-analysis that challenges the status quo, pitting Noninvasive Ventilation (NIV) directly against standard Bag-V
The Resus Recap: Vasoplegia
The Resus Recap: Vasoplegia Jan 19, 2026 417 A new podcast of just me in my car
Balanced crystalloids versus normal saline for trauma resuscitation: A systematic review and meta-analysis
Balanced crystalloids versus normal saline for trauma resuscitation: A systematic review and meta-analysis Jan 6, 2026 859 Is the reign of "Normal" Saline over, or is the classic bag of salt water actually the hero of the trauma bay? For years, the critical care community has debated whether we should abandon 0.9% sodium chloride in favor of balanced crystalloids like Lactated Ringer’s or Plasma-Lyte to protect the kidneys and prevent acidosis. But a new study suggests we might be writing off saline too soon—
Ketamine or Etomidate for Tracheal Intubation of Critically Ill Adults
Ketamine or Etomidate for Tracheal Intubation of Critically Ill Adults Dec 17, 2025 783 Is Ketamine really the "hemodynamically stable" hero of airway management, or have we been unfairly vilifying Etomidate for decades? The debate over the perfect induction agent for critically ill patients just got a major influx of data that flips conventional wisdom on its head .   In this episode, we break down the landmark "RSI" trial, a massive multicenter randomized co
Efficacy of HFNC + NIV as initial oxygen therapy in acute respiratory failure: Meta-analysis
Efficacy of HFNC + NIV as initial oxygen therapy in acute respiratory failure: Meta-analysis Dec 10, 2025 780 Is the "best of both worlds" actually saving lungs, or just complicating care?  Theoretically, combining the powerful pressure support of Non-Invasive Ventilation (NIV) with the comfort and washout mechanisms of High-Flow Nasal Cannula (HFNC) sounds like the ultimate strategy to prevent intubation . But does this physiological synergy actually translate to patient survival?&nbsp
Is ketamine safe for traumatic brain injury? A systematic review and meta-analysis
Is ketamine safe for traumatic brain injury? A systematic review and meta-analysis Dec 1, 2025 866 For decades, a single dogma has ruled neurotrauma resuscitation: Never use ketamine in TBI. The historical fear that ketamine spikes intracranial pressure (ICP) has kept one of the most versatile, hemodynamically friendly induction agents on the shelf—but is that fear based on fact or outdated physiology?     In this episode, we dissect a massive 2026 systematic review and
Liberal or Restrictive Postoperative Transfusion in Patients at High Cardiac Risk The TOP Randomized Clinical Trial
Liberal or Restrictive Postoperative Transfusion in Patients at High Cardiac Risk The TOP Randomized Clinical Trial Nov 25, 2025 927 In this episode, we tackle one of the most persistent questions in perioperative care: how low is too low when it comes to hemoglobin in high-risk cardiac patients after major surgery? The long-standing restrictive threshold of 7 g/dL has been considered safe for years, but the TOP Trial challenges that comfort zone. More than 1,400 high-risk veterans were randomized to either a liberal t
Positive communication for decreasing burnout in intensive‐care‐unit staff: a cluster‐randomized trial
Positive communication for decreasing burnout in intensive‐care‐unit staff: a cluster‐randomized trial Nov 7, 2025 969 Can a Single Word Change the Culture of an ICU? Burnout is an epidemic in our Intensive Care Units, affecting staff well-being, patient care, and even hospital costs. But what if the solution to this widespread problem was simpler than we think? This week, we’re diving into the Hello Trial, a massive 1:1 cluster-randomized controlled trial conducted across 370 ICUs in 60 countries. Resear

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