Sabrina Halper Show
Sabrina Halper explores the intersection of the mind, technology, and existential questions. The podcast delves into how human consciousness interacts with machines and what that means for our understanding of life. Episodes likely feature discussions on philosophy, psychology, and the implications of artificial intelligence, aiming to uncover deeper meaning in a rapidly changing world.
Episodes
Google’s $32B Bet on Cybersecurity in the AI vs. AI Era | Wiz Co-Founder Yinon Costica
Yinon Costica co-founded Wiz, which Google acquired for $32 billion in the largest acquisition in its history. I sat down with him at Wiz HQ in Tel Aviv to talk about the race to secure a world increasingly run by AI.Wiz on X: https://x.com/wiz_ioSabrina Halper on X: https://x.com/SabrinaHalperPRESENTING SPONSORThe Sabrina Halper Show is presented by micro1.micro1 is building the infrastructure fo
Alex Atallah (OpenRouter, OpenSea): Agents Will Drive Most of GDP Growth
Alex Atallah co-founded OpenRouter in 2023 and recently signed an agreement to be acquired by Stripe for a reported ~$7B+. Before that, he co-founded OpenSea, the world’s largest NFT marketplace. Alex is a deep thinker and a one-of-a-kind company builder. I was honored to sit down with him again.We also talk about why OpenRouter and Stripe fit together, and their shared belief in an economy where
What the Data Reveals About How AI Will Change Work | David Holtz (Professor & AGI Economics Researcher)
Most of what you hear about AI's impact is a projection. David Holtz has the data. He’s behind some of the most rigorous studies of AI’s actual impact today. And the results are surprising. His work cuts through the noise around AI to a key question: what is AI actually doing to people, companies, and the economy today?David is a professor at Columbia, currently on leave to lead AGI economics
Factory’s Matan Grinberg on Recursive Self-Improvement, Chinese Models & Lessons From String Theory
Matan Grinberg left a string theory PhD at Berkeley to start Factory, betting on full autonomous software engineering in 2023. It started with a cold email to Sequoia’s Shaun Maguire and a three-hour walk that helped convince Matan to leave his PhD and build a company. Three years later, Factory is valued at $1.5B, with recent reports putting its newest valuation north of $3.5B.We get into: what s
Reed Jobs’ Fight Against Cancer
I sat down with Reed Jobs to discuss one of medicine’s hardest problems: why we’ve spent hundreds of billions of dollars fighting cancer, yet still don’t have a cure.Reed explains why there may never be a cure for cancer and why that’s actually the wrong goal. Instead, the future is making cancer a disease that no one dies from.He gives an inside look at Yosemite, the venture firm he founded to re
How He’s Leading the Race to Reverse Aging - New Limit's Cofounder Jacob Kimmel
The secret to staying young may already be inside your cells. We just need to figure out how to unlock it.NewLimit is one of the world's leading longevity companies, co-founded by Coinbase founder Brian Armstrong, investor Blake Byers, and stem cell biologist Jacob Kimmel. NewLimit has already shown it can take old human liver and immune cells and restore them to a younger, healthier-working s
Engineering Biology With AI: The Future of Medicine
Jack Dent, co-founder of Chai Discovery, gives us a look at how AI could change the way we discover drugs, understand biology, and treat disease. Jack went from cold-emailing Stripe and joining as a teenager to co-founding Chai Discovery, the AI drug design company Sam Altman asked him and Josh to start years before they did. Chai has since raised $225M from investors including OpenAI and Thrive C
How She Became One of Wall Street’s Most Successful Investors
Keri Findley, founder of Thiel-Backed fund Tacora Capital, shares a rare glimpse into her life and career: her path to Wall Street, eventually becoming one of the youngest partners at hedge fund Third Point while building its structured credit business from scratch, founding Tacora Capital with Peter Thiel anchoring the first fund as his biggest check ever.Along with wild success comes a target on
AI Has Taste Now. The Radical Disruption Coming for Hollywood | Edward Saatchi, Fable Studios
Edward Saatchi (Saatchi & Saatchi family, former Head of Oculus Story Studio, Founder of Fable Studios) joins us to make the case that Hollywood is sleepwalking into the most radical disruption in the history of storytelling."Creativity is at a deep blue and Kasparov moment""AI isn't just a tool in the toolbox for filmmakers. It's a competitor"We talk about:★ Whethe
Moxie Marlinspike, Founder of Signal
Moxie Marlinspike founded Signal, the nonprofit privacy messenger used by millions. He’s now building Confer, a fully private, end-to-end encrypted AI chat. This conversation covers everything.TIMESTAMPS:00:00 Intro 01:09 Building Physical World Projects Centered on Experiences07:43 Tales from Hitchhiking15:04 The Birth of Signal22:23 Privacy in the Digital Age31:21 Introducing Confer: Private AI
When AI Becomes Conscious, How Will We Even Know? — Ken Liu
Ken Liu: Renowned sci-fi author of The Paper Menagerie, The Hidden Girl and Other Stories, and his new book All That We See or Seem; producer of Pantheon; futurist who works with world governments to prepare for what’s ahead. TIMESTAMPS:(0:00) Introduction(1:41) Mechanism vs meaning: what science explains vs what stories explain(5:47) What is consciousness, really?(6:42) Psychedelics and the myste
Isabelle Boemeke - The Real Story of Nuclear: Fear, Politics, and the Grid We Need for AI
Isabelle Boemeke went from Brazilian model to the internet’s most creative nuclear advocate who led the largest pro nuclear rally in US history. In this episode, we talk about nuclear energy's wild history, political drama, and what America’s energy grid needs to look like to keep up with the future demands.Shownotes: 0:00 : Introduction1:37 : Growing up in rural Brazil3:44 : Getting to the Un
OpenAI’s Isa Fulford on Building Deep Research, ChatGPT’s Agent, and the Future of the Internet
Isa Fulford is only a few years out of school and is already the mind behind Deep Research and ChatGPT Agent - two of the most important and ambitious projects at OpenAI. She’s a close friend from our Stanford days, someone I adore, and someone the world is going to hear a lot more about in coming years.We talk about how her upbringing and violin training shaped the discipline behind her professio
Life After AGI — Richard Ngo (Philosopher & Researcher, ex-OpenAI / DeepMind)
Richard Ngo is a leading AI philosopher and researcher, formerly at OpenAI and DeepMind. We discuss what life looks like once we have AGI and how every aspect of the human experience could change.TIMESTAMPS00:00 – Introduction01:44 – Technology as an Inequality Engine03:52 – AI as a Personal Tutor vs. Distraction Machine06:11 – Therapy, Coaching, and Emotional Mediation09:16 – The Future of Work a
The AI Revolution in Music: A Conversation with DAOuda Leonard, Manager of Grimes and Founder of CreateSafe
In this episode, Sabrina Halper sits down with DAOuda Leonard, Grimes' manager and founder of music tech studio CreateSafe, which just launched its generative AI-powered platform Triniti. Triniti enables artists to create an AI voice clone, generate text-to-audio samples, ask a chatbot music industry-related questions, monetize creations and manage music IP.
Subscribe to stay up to date on al
Eric Jang on Humanoid Robots, Why AI is Good For You, and a Future of Abundance.
In this episode, Sabrina Halper sits down with Eric Jang. Eric is the VP of AI at 1X Technologies, a humanoid robot company built to benefit society, with investment led by OpenAI. He also published AI is Good for You, a book about the last 10 Years and the next 10 Years of Artificial Intelligence (link to buy attached below). Previously, Eric was a senior research scientist at Google on their rob
Martin Varsavsky on fertility and birth rate decline, gene editing, modern evolution, and why humanity needs more babies.
In this episode, Sabrina Halper sits down with renowned entrepreneur Martin Varsavsky. Martin has founded five unicorn companies across industries. He discusses his cutting edge work in the fertility space and how technology will revolutionize our biology.
Timestamps:
(0:00) - Intro
(1:30) - Catalyst for building in fertility
(3:00) - Reasons for increased infertility in society
(7:00) - Climate
Delian on Varda's space drugs, Founders Fund, and Silicon Valley's history of mentorship.
Delian Asparouhov is the co-founder of Varda Space, the startup that is manufacturing products in space to benefit life on Earth. He is also a partner at Founders Fund.
The first 30 minutes of this episode cover all things space: Varda, investing and building in Space, Elon's role in pushing the industry forward, working in highly-regulated industries, inception of ideas.
The second 30 minutes
Living Carbon's Maddie Hall on bioengineering super trees to help fight climate change, synthetic bio's potential, carbon credits, lessons from Sam Altman & using LLMs to understand animals.
Maddie Hall is the co-founder and CEO of Living Carbon, a plant bio-tech company growing genetically modified poplars and pines capable of absorbing much more carbon dioxide from the atmosphere than regular trees. Previously, she worked on special projects at Y Combinator and OpenAI.
Follow https://twitter.com/TomorrowTalk_ to stay up to date on all the best clips and upcoming episodes! Follow Ma
Tye Sheridan and Nikola Todorovic on harnessing AI to revolutionize special effects, founding Wonder Dynamics, the future of content, and Hollywood’s tech roots.
Tye Sheridan, the lead actor in films such as Ready Player One, X-Men, and Mud, and Nikola Todorovic, award-winning filmmaker and visual effects supervisor, met on a set in 2016. They quickly became best friends, and eventually cofounders of Wonder Dynamics, a company building AI software that makes VFX special effects affordable and accessible on a browser, ultimately empowering a whole new gener
Bryan Johnson on reducing his biological age, longevity, human alignment, & negotiating with pain.
Bryan Johnson sits down with HOF investor Sabrina Halper for an in-depth conversation that spans philosophy, biology, and technology. Bryan Johnson is the world's most measured human. He is investing millions to slow and reverse his aging. In 2021, he set a world record by reducing his epigenetic age by 5.1 years in 7 months. In this conversation, Bryan confronts many of the criticisms around
Elad Gil on the power of peer groups, investing in 40+ unicorns, today's AI ecosystem, and staying dynamic.
In this episode, Elad sits down with Sabrina Halper for a candid conversation about all things technology. You'll hear his thoughts on:
1.How to develop a long-term career in technology:
-The power of peer groups and cohorts
-Which jobs to pursue
-Re-inventing yourself
-Living in the physical hubs
2.Advice for founders of startups and growth-stage companies:
-Why large companies stagnate an
Sahil Lavingia on growing Gumroad to $100M, today's AI ecosystem, finding a business idea, an Isaac Asimov future, his 300k Twitter audience + more
In this episode, Sabrina Halper sits down with Sahil Lavingia for an in-depth conversation that goes far and wide.
They discuss:
-his journey dropping out of USC to join Pinterest as the 2nd employee
-founding and scaling Gumroad to $100M
-his advice for others looking to build profitable products and companies
-the current AI wave: which companies excite him, what he's been building, how th
Ben Lamm, Colossal Founder & CEO: De-Extinction, Artificial Wombs & the Future of Genetics
In this episode, Sabrina sits down with Ben Lamm, CEO & Founder of the biotechnology and genetic engineering company Colossal. Ben is a serial entrepreneur who has started several moonshot companies, including AI company Hypergiant. Ben co-founded Colossal alongside renowned geneticist George Church. Together they are working to genetically resurrect key species, such as the wooly mammoth, the
Future of Virtual & Augmented Reality, How AI will Disrupt Gaming, Apple’s AR play, Meta’s $36B Rebrand, and How to Approach Building in the Space.
In this episode, host Sabrina Halper sits down with Felix Hartmann (Hartmann Capital), Jonathan Ovadia (founder, AEXLABS), and Dr Doom (founder, LIV). The seasoned guests discuss the biggest limitations to the VR industry to date, Meta’s re-brand and $36B investment, how Apple might enter the space, generative AI's role in increasing productivity and building games more efficiently, how augmented
Matt Krisiloff & Roon on Turning Stem Cells into Human Eggs, Longevity, OpenAI, AI's Role in Biotech, + More
In this episode, special guest host Roon sits down with Matt Krisiloff, the founder of Conception and SciFounders. The pair discuss Conception's work with in vitro gametogenesis: turning stem cells into human eggs, which could potentially allow for same sex couples or older women to have biological children. They also discuss the fertility crisis, artificial wombs and genetic selection, his early
roon(@TSZZL) on Elon, Growing a Famous Pseudonym, Secret AI Projects, Rahul Ligma, Vitalik + everything else on our minds
Roon is the Twitter pseudonym we all love. You've likely come across @Tszzl on Twitter, where he has grown over 56k followers under his pseudonymous name "roon" for his smart and edgy takes. He's an AI expert, engineer, an SF stan, and overall techno-optimist. On this episode you'll hear about his thoughts on Elon Musk, Twitter, generative AI, which new AI companies will find success, China's AI p
Changing US Law to Build America’s First Federally Regulated Events-Based Exchange, with Kalshi Co-founder & CEO Tarek Mansour.
Tarek Mansour is the 25 year old co-founder and CEO of Kalshi, America's first federally regulated exchange where you can trade on events, just like you would a stock or a commodity. During his time at Goldman Sachs, Tarek was set to help clients hedge their investments during Brexit, but there was no direct way to do it. In 2018, he started Kalshi with fellow MIT classmate Luana Lopes Lara. After
The Robot Lawyer that Helped Consumers Save Over $100M, with DoNotPay Founder Joshua Browder
Today's guest is Joshua Browder, the co-founder and CEO of DoNotPay, the world's first robot lawyer. He has helped consumers win back over $100M in parking tickets, subscriptions, and more. His mission is to use technology to empower consumers to represent themselves and protect their rights. In this episode, Joshua speaks to host Sabrina Halper about his childhood during his father Bill
Saving Millions of Lives Using Blood to Catch Cancer Early, with BillionToOne founder Oguzhan Atay
Oguzhan Atay is the founder & CEO of BillionToOne, a molecular diagnostics company that is redefining cancer care and pre-natal genetic testing. Oguzhan developed a liquid biopsy tool to test DNA through blood, rather than tissue samples. His approach is way less invasive and way more accurate. The company has raised over $210M. In this episode, Oguzhan speaks to Host Sabrina Halper and Co-hos
Tom Brady’s Co-Founder on Building an Enduring NFT Platform, His Outlook on Crypto Winter, & Earning the Support Icons and Leaders in Crypto & Sports (Katie Haun, Tiger Woods, SVP of Apple, etc.)
Autograph’s Co-founder Tom Brady is widely known. The other co-founder, and CEO, is Dillon Rosenblatt, a 24 year old, second time founder. Dillon first began his entrepreneurial journey when he started Tutors, a company to connect tutors and students, at age 15. After attending USC’s Iovine and Young Academy for entrepreneurship, he explored the idea of starting a crypto hedge fund which began a d
Henrique Dubugras, Co-founder & CEO of Fintech Unicorn Brex
In this debut episode, host Sabrina Halper sits down with Henrique Dubugras, the Co-Founder and Co-CEO of Brex, a credit card and financial toolkit for startups, valued at $12.3B. As a 16 year old living in the middle of Brazil, Henrique founded Pagar.me, which did over $1.5B in sales. He then went on to attend Stanford University for 6 months, until dropping out to join Y Combinator and start Bre
Recommended
Infinite Health with Dr. Arasi Maran
The Daily
World News Tonight with David Muir
English Vocabulary Help
The Joe Rogan Experience
TED Talks Daily
Learn English B1 with Daily News | English Listening Practice
Talk About Talk - Executive & Leadership Communication Skills
English with Olivia | Slow Conversations & Vocabulary
Stand In The Circle
SLOW ENGLISH PODCAST (A1-A2) With Subtitles | Daily Videos | English With Us Podcast
Learn English A2 with Daily News | Simple English Listening Practice
