Home Podcasts Longevity Optimization with Kayla Barnes-Lentz
Longevity Optimization with Kayla Barnes-Lentz

Longevity Optimization with Kayla Barnes-Lentz

Kayla Barnes-Lentz 158 Episodes Sep 17, 2026

Maximizing Human Health and Performance. We discuss: optimal health, nutrition, high-performance, cognitive excellence, biohacking, longevity and more with top experts around the world. Hosted by Kayla Barnes-Lentz.

Episodes

Dr. Abud Bakri, MD: Thymus Health, Circadian Biology, and the Truth About Peptides
Dr. Abud Bakri, MD: Thymus Health, Circadian Biology, and the Truth About Peptides Sep 17, 2026 01:07:46 Most longevity conversations focus on the brain, heart, muscle, and metabolism. Far less attention goes to the thymus, an immune organ that starts shrinking almost as soon as puberty ends, and new research suggests it may be quietly linked to fertility, hormones, and even how millions of women taking birth control are aging on the inside.I sit down with Dr. Abud Bakri, a board-certified internal m
Dr. Will Cole: How to Heal Your Cells, Leaky Gut, Light Exposure, and Why Your Gut Sets the Pace To Aging
Dr. Will Cole: How to Heal Your Cells, Leaky Gut, Light Exposure, and Why Your Gut Sets the Pace To Aging Sep 10, 2026 01:00:18 We talk about aging like it happens to a whole person at once. It doesn't. It happens organ by organ, at different speeds, and most people never find out which part of them is running ahead until something breaks.Dr. Will Cole has spent sixteen years running one of the first functional medicine telehealth centers in the world, and he came to this conversation with a case that is both clinical
Dr. Tania Dempsey, MD: Mast Cell Activation Syndrome, PMOS, and the Hidden Cause of Women's Chronic Symptoms
Dr. Tania Dempsey, MD: Mast Cell Activation Syndrome, PMOS, and the Hidden Cause of Women's Chronic Symptoms Sep 3, 2026 01:17:23 Most women who deal with unexplained allergies, stubborn inflammation, heavy periods or a PMOS (formerly PCOS) diagnosis are never told to look at the same underlying cause: an immune cell most doctors were never taught to test for.Dr. Tania Dempsey, MD, trained in internal medicine at Johns Hopkins before leaving conventional practice to focus on mast cell activation syndrome, a condition she bel
Dr. Margie Davenport, PhD: Exercise in Pregnancy, the 140 BPM Myth, and Why Pregnancy Complications Predict Heart Disease
Dr. Margie Davenport, PhD: Exercise in Pregnancy, the 140 BPM Myth, and Why Pregnancy Complications Predict Heart Disease Aug 27, 2026 00:59:34 Pregnancy has long been treated as a season to slow down and play it safe. The data tells a different story, and it starts with a number most women were taught to fear.Dr. Margie Davenport, PhD, is an exercise physiologist and professor at the University of Alberta who has spent over a decade studying how the body moves through pregnancy, postpartum, and the years before. What stayed with me most:
Dr. Gabrielle Lyon, DO: Muscle as the Organ of Longevity, Protein Mistakes, and the Truth About Menopause Muscle Loss
Dr. Gabrielle Lyon, DO: Muscle as the Organ of Longevity, Protein Mistakes, and the Truth About Menopause Muscle Loss Aug 20, 2026 01:02:47 Muscle is not just something you build in the gym. Dr. Gabrielle Lyon has spent her career arguing it's the organ that actually determines how well you age, and almost none of us have been taught to think about it that way.Dr. Gabrielle Lyon, DO, is the founder of Muscle-Centric Medicine and the New York Times bestselling author of Forever Strong. She's spent over two decades studying musc
Dr. Christin Glorioso, MD, PhD: The Alzheimer's Blood Test, How to Cut Your Dementia Risk by 30%, and Why Women Are at Higher Risk
Dr. Christin Glorioso, MD, PhD: The Alzheimer's Blood Test, How to Cut Your Dementia Risk by 30%, and Why Women Are at Higher Risk Aug 6, 2026 01:11:40 Brain aging does not start when memory loss shows up. It starts around age 25, decades before anyone notices anything is different. By the time a symptom appears, the window for the highest-leverage prevention has usually already closed.Today I'm talking with Dr. Christin Glorioso, an MD and PhD who has spent her career studying Alzheimer's, partly because of her own family history and par
Dr. Colleen Cutcliffe, PhD: Natural GLP-1 Production, Fiber Deficiency, Akkermansia and the Gut Microbiome Connection
Dr. Colleen Cutcliffe, PhD: Natural GLP-1 Production, Fiber Deficiency, Akkermansia and the Gut Microbiome Connection Jul 31, 2026 01:17:31 Most people think of the gut as a digestive organ. It is not. It is the upstream controller of your metabolism, immune function, brain health, skin, and hormones and almost everyone is running it on a depleted, misfed microbiome without knowing it.Dr. Colleen Cutcliffe, PhD is the co-founder and CEO of Pendulum Therapeutics, holds a PhD in biochemistry from Johns Hopkins, and spent over 15 years i
Dr. Elizabeth Yurth, MD: Muscle Building in Midlife, Joint Regeneration, Peptide Protocols, and Why Osteoarthritis Is Not Wear and Tear
Dr. Elizabeth Yurth, MD: Muscle Building in Midlife, Joint Regeneration, Peptide Protocols, and Why Osteoarthritis Is Not Wear and Tear Jul 2, 2026 02:41:13 Dr. Elizabeth Yurth, co-founder of Boulder Longevity Institute, is one of the rare physicians who spent 30 years in orthopedic and sports medicine before pivoting to longevity and regenerative medicine. This episode covers joint health in women, osteoarthritis, bone density, peptides, perimenopause, hormones, mitochondrial health, and the regenerative protocols most women have never been offered.W
Dr. Wendy Troxel, PhD: Insomnia, Sleep Apnea, Perimenopause Sleep, and the Treatment That Outperforms Every Medication
Dr. Wendy Troxel, PhD: Insomnia, Sleep Apnea, Perimenopause Sleep, and the Treatment That Outperforms Every Medication Jun 25, 2026 01:14:12 Sleep is not just something women need more of. It is something women struggle with in ways that are fundamentally different from men and almost nobody explains why.Dr. Wendy Troxel, PhD is one of the most respected sleep scientists in the world. Her research has shaped sleep policy in the US military. Her book, Sharing the Covers, is one of the most practical and science-backed guides to partnere
Dr. Sharon Horesh Bergquist, MD: Hormetic Stress, Women’s Resilience, and the 5 Stressors That Support Longevity
Dr. Sharon Horesh Bergquist, MD: Hormetic Stress, Women’s Resilience, and the 5 Stressors That Support Longevity Jun 18, 2026 01:20:13 Avoiding stress at all costs may actually be making you less resilient.In this episode, Dr. Sharon Horesh Bergquist reframes stress as one of the body’s most overlooked tools for longevity. The right kind of challenge can activate repair, strengthen resilience, improve metabolic health, and help the body adapt in ways that support healthier aging over time. Rather than trying to eliminate stress c
Dr. Martha Gulati, MD: Women's Heart Disease, Female-Specific Risk Factors, and What Medicine Gets Wrong About Cardiovascular Health
Dr. Martha Gulati, MD: Women's Heart Disease, Female-Specific Risk Factors, and What Medicine Gets Wrong About Cardiovascular Health Jun 11, 2026 01:01:06 Heart disease is not only a man's disease. It is the number one killer of women, responsible for ten times more deaths than breast cancer. And yet most women have never had a real conversation about their cardiovascular risk, because the medical system was not built to catch it in them.Dr. Martha Gulati is the Director of Preventive Cardiology and Associate Director of the Barbra Streisand Wom
Dr. Jolene Brighten, ND - Endometriosis, Adenomyosis, PMDD, PMOS and Postpartum Hormones
Dr. Jolene Brighten, ND - Endometriosis, Adenomyosis, PMDD, PMOS and Postpartum Hormones Jun 4, 2026 01:47:49 Women are often told that painful periods, irregular cycles, bloating, mood changes, fatigue, brain fog, postpartum symptoms, and hormonal shifts are “normal.”But common does not mean something should be ignored.In this episode, Dr. Jolene Brighten, ND joins me for a practical deep dive into female-specific conditions that are too often missed, minimized, or treated in isolation, including endomet

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