Home Podcasts Longevity Optimization with Kayla Barnes-Lentz
Longevity Optimization with Kayla Barnes-Lentz

Longevity Optimization with Kayla Barnes-Lentz

Kayla Barnes-Lentz 158 Episodes Aug 20, 2026

Maximizing Human Health and Performance. We discuss: optimal health, nutrition, high-performance, cognitive excellence, biohacking, longevity and more with top experts around the world. Hosted by Kayla Barnes-Lentz.

Episodes

Dr. Gabrielle Lyon, DO: Muscle as the Organ of Longevity, Protein Mistakes, and the Truth About Menopause Muscle Loss
Dr. Gabrielle Lyon, DO: Muscle as the Organ of Longevity, Protein Mistakes, and the Truth About Menopause Muscle Loss Aug 20, 2026 01:02:47 Muscle is not just something you build in the gym. Dr. Gabrielle Lyon has spent her career arguing it's the organ that actually determines how well you age, and almost none of us have been taught to think about it that way.Dr. Gabrielle Lyon, DO, is the founder of Muscle-Centric Medicine and the New York Times bestselling author of Forever Strong. She's spent over two decades studying musc
Dr. Christin Glorioso, MD, PhD: The Alzheimer's Blood Test, How to Cut Your Dementia Risk by 30%, and Why Women Are at Higher Risk
Dr. Christin Glorioso, MD, PhD: The Alzheimer's Blood Test, How to Cut Your Dementia Risk by 30%, and Why Women Are at Higher Risk Aug 6, 2026 01:11:40 Brain aging does not start when memory loss shows up. It starts around age 25, decades before anyone notices anything is different. By the time a symptom appears, the window for the highest-leverage prevention has usually already closed.Today I'm talking with Dr. Christin Glorioso, an MD and PhD who has spent her career studying Alzheimer's, partly because of her own family history and par
Dr. Colleen Cutcliffe, PhD: Natural GLP-1 Production, Fiber Deficiency, Akkermansia and the Gut Microbiome Connection
Dr. Colleen Cutcliffe, PhD: Natural GLP-1 Production, Fiber Deficiency, Akkermansia and the Gut Microbiome Connection Jul 31, 2026 01:17:31 Most people think of the gut as a digestive organ. It is not. It is the upstream controller of your metabolism, immune function, brain health, skin, and hormones and almost everyone is running it on a depleted, misfed microbiome without knowing it.Dr. Colleen Cutcliffe, PhD is the co-founder and CEO of Pendulum Therapeutics, holds a PhD in biochemistry from Johns Hopkins, and spent over 15 years i
Dr. Elizabeth Yurth, MD: Muscle Building in Midlife, Joint Regeneration, Peptide Protocols, and Why Osteoarthritis Is Not Wear and Tear
Dr. Elizabeth Yurth, MD: Muscle Building in Midlife, Joint Regeneration, Peptide Protocols, and Why Osteoarthritis Is Not Wear and Tear Jul 2, 2026 02:41:13 Dr. Elizabeth Yurth, co-founder of Boulder Longevity Institute, is one of the rare physicians who spent 30 years in orthopedic and sports medicine before pivoting to longevity and regenerative medicine. This episode covers joint health in women, osteoarthritis, bone density, peptides, perimenopause, hormones, mitochondrial health, and the regenerative protocols most women have never been offered.W
Dr. Wendy Troxel, PhD: Insomnia, Sleep Apnea, Perimenopause Sleep, and the Treatment That Outperforms Every Medication
Dr. Wendy Troxel, PhD: Insomnia, Sleep Apnea, Perimenopause Sleep, and the Treatment That Outperforms Every Medication Jun 25, 2026 01:14:12 Sleep is not just something women need more of. It is something women struggle with in ways that are fundamentally different from men and almost nobody explains why.Dr. Wendy Troxel, PhD is one of the most respected sleep scientists in the world. Her research has shaped sleep policy in the US military. Her book, Sharing the Covers, is one of the most practical and science-backed guides to partnere
Dr. Sharon Horesh Bergquist, MD: Hormetic Stress, Women’s Resilience, and the 5 Stressors That Support Longevity
Dr. Sharon Horesh Bergquist, MD: Hormetic Stress, Women’s Resilience, and the 5 Stressors That Support Longevity Jun 18, 2026 01:20:13 Avoiding stress at all costs may actually be making you less resilient.In this episode, Dr. Sharon Horesh Bergquist reframes stress as one of the body’s most overlooked tools for longevity. The right kind of challenge can activate repair, strengthen resilience, improve metabolic health, and help the body adapt in ways that support healthier aging over time. Rather than trying to eliminate stress c
Dr. Martha Gulati, MD: Women's Heart Disease, Female-Specific Risk Factors, and What Medicine Gets Wrong About Cardiovascular Health
Dr. Martha Gulati, MD: Women's Heart Disease, Female-Specific Risk Factors, and What Medicine Gets Wrong About Cardiovascular Health Jun 11, 2026 01:01:06 Heart disease is not only a man's disease. It is the number one killer of women, responsible for ten times more deaths than breast cancer. And yet most women have never had a real conversation about their cardiovascular risk, because the medical system was not built to catch it in them.Dr. Martha Gulati is the Director of Preventive Cardiology and Associate Director of the Barbra Streisand Wom
Dr. Jolene Brighten, ND - Endometriosis, Adenomyosis, PMDD, PMOS and Postpartum Hormones
Dr. Jolene Brighten, ND - Endometriosis, Adenomyosis, PMDD, PMOS and Postpartum Hormones Jun 4, 2026 01:47:49 Women are often told that painful periods, irregular cycles, bloating, mood changes, fatigue, brain fog, postpartum symptoms, and hormonal shifts are “normal.”But common does not mean something should be ignored.In this episode, Dr. Jolene Brighten, ND joins me for a practical deep dive into female-specific conditions that are too often missed, minimized, or treated in isolation, including endomet
Dr. Izabella Wentz: IBS Root Causes, Leaky Gut, Autoimmunity, and How To Start Healing Your Gut
Dr. Izabella Wentz: IBS Root Causes, Leaky Gut, Autoimmunity, and How To Start Healing Your Gut May 28, 2026 00:56:08 Less than 25% of people with IBS get real relief from conventional medicine. That number tells you everything about how the current approach is failing.Most people with IBS have been told it is stress, told to take medication, and sent home. But irritable bowel syndrome is not one condition, it is a label applied to a cluster of symptoms that can have 20 to 40 completely different root causes. And
Dr. Scott Sherr, MD: Why Stress Blocks Healing: Mitochondria, Immune Aging, Hyperbaric Oxygen, and Methylene Blue
Dr. Scott Sherr, MD: Why Stress Blocks Healing: Mitochondria, Immune Aging, Hyperbaric Oxygen, and Methylene Blue May 21, 2026 01:31:45 There is a state where the body gets locked in sympathetic activation and mitochondrial dysfunction at the same time and no matter what supplements you take, no matter what protocols you run, nothing actually works. Dr. Scott Sherr calls it the sympathetic spiral of doom, and in this episode we break down exactly what it is, why so many people are stuck in it without knowing it, and the right sequ
Dr. Poonam Desai: The 5 Labs Women Need, Heart Disease Risk, Microplastics, and Perimenopause
Dr. Poonam Desai: The 5 Labs Women Need, Heart Disease Risk, Microplastics, and Perimenopause May 14, 2026 01:02:30 Most women have had bloodwork done. What most women haven't had is the right bloodwork. In this episode, Dr. Poonam Desai, double board certified in lifestyle and emergency medicine, NAM certified in menopause care, and founder of Longevity Place and Her Longevity, breaks down the five labs she runs on every female patient, the optimal values most physicians aren't targeting, and why the s
Prof. Belinda Beck, PhD: Bone Health: Building Strong Bones, Preventing Age-Related Loss, And Reversing Osteoporosis With Evidence-Based Exercise
Prof. Belinda Beck, PhD: Bone Health: Building Strong Bones, Preventing Age-Related Loss, And Reversing Osteoporosis With Evidence-Based Exercise May 7, 2026 01:10:54 Most women are not thinking about their bones until a fracture happens or a scan comes back alarmingly. By then, the window for the most impactful intervention has often been narrowing for decades. Bone density peaks around age 18, not 30 as widely believed and the slow decline that follows is largely silent until it isn't.Professor Belinda Beck, PhD has spent more than two decades studying ex

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