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Rapid Response

Rapid Response

WaitWhat 421 Episodes Oct 13, 2026

Rapid Response features candid conversations with today's top business leaders navigating real-time challenges. Hosted by former Fast Company editor-in-chief Bob Safian, the podcast explores what is most important to pay attention to when striving to innovate, create, and lead. It is produced by the team behind Masters of Scale.

Episodes

The AI race to save American science and reshape medicine forever
The AI race to save American science and reshape medicine forever Oct 13, 2026 00:27:48 Renee Wegrzyn spent her career building the future of American science — including ARPA-H, the White House agency created to accelerate health breakthroughs. Then the Trump administration showed her the door. Wegrzyn co-founded Transfyr to tackle what she calls one of the most overlooked issues in science: the magic hands problem. She joins Rapid Response to explain why fixing this unglam
Airbnb’s bet on an IRL future, with Brian Chesky
Airbnb’s bet on an IRL future, with Brian Chesky Oct 9, 2026 00:32:10 This episode of Rapid Response first aired in 2025.Live on stage at Masters of Scale Summit in San Francisco, Airbnb co-founder and CEO Brian Chesky explores what role business could and should play in building the future. He shares his candid perspective on politics, creativity, and AI — taking listeners from Airbnb’s humble beginnings to bold plans for the company’s future. Through a de
Kalshi vs. Everyone: Co-Founder Luana Lopes Lara on the lawsuits and the long game
Kalshi vs. Everyone: Co-Founder Luana Lopes Lara on the lawsuits and the long game Oct 6, 2026 00:34:23 Prediction markets incentivize truth. Everything else incentivizes clickbait. That's the core argument Luana Lopes Lara makes for Kalshi — the prediction market platform she co-founded that has gone from $5 billion to $22 billion in valuation in under a year, and is now being sued by New York's attorney general for $36 billion. Luana joins Rapid Response to make the case that Kalshi is fu
Meet Tilly Norwood and her creator: AI "actor," death threats, and new Hollywood
Meet Tilly Norwood and her creator: AI "actor," death threats, and new Hollywood Oct 2, 2026 00:29:25 What happens when you interview an AI? Bob Safian found out, and while it didn't break out into Cantonese, it was stranger than he expected. This episode is split in two: first, a conversation with Eline van der Velden, the Dutch actress-turned-tech-founder who created Tilly Norwood, the AI "actor" who sent Hollywood into a spiral. Then, Bob sits down with Tilly itself. Eline explains how
Halloween meets GLP-1s: Hershey’s candy Super Bowl, with CEO Kirk Tanner
Halloween meets GLP-1s: Hershey’s candy Super Bowl, with CEO Kirk Tanner Sep 29, 2026 00:27:11 The second a brand like Hershey stops being culturally relevant, says its CEO Kirk Tanner, you should be worried. He joins Rapid Response to explain exactly what he's doing to make sure that never happens. Tanner also reveals why GLP-1 users are actually good for the candy business, how AI is now routing Hershey's sales force in real time through Target and Walmart, and why the Reese's Or
Chobani & Patagonia CEOs break down where values meet profit
Chobani & Patagonia CEOs break down where values meet profit Sep 25, 2026 00:27:13 This episode of Rapid Response first aired in 2025. Live on stage at Masters of Scale Summit in San Francisco, Patagonia CEO Ryan Gellert and Chobani CEO Hamdi Ulukaya joined the New York Times’ David Gelles to explore the intersection of values and commerce. They reveal their different strategies for dealing with an activist White House, the pressure for what David calls “anticipatory co
Rebranding in a war zone, with Prosper Global (formerly Mercy Corps)
Rebranding in a war zone, with Prosper Global (formerly Mercy Corps) Sep 22, 2026 00:26:45 The world has never faced so many humanitarian crises at once, and the systems built to respond to them are fraying. Tjada McKenna, CEO of Prosper Global — the organization long known as Mercy Corps — joins Rapid Response during UN General Assembly week to share what she's seeing firsthand from Syria to Sudan to Ukraine to Gaza, and why she rebranded a 40-year-old institution in the middl
Pioneers of AI:  The deep AI shifts that will reshape our lives
Pioneers of AI: The deep AI shifts that will reshape our lives Sep 19, 2026 00:38:14 For nearly two decades, Amy Webb's annual Tech Trends Report was required reading for anyone trying to keep up with technology. But this year, Webb killed the report and replaced it with something more applicable for leaders in an AI era.In this episode, CEO of Future Today Strategy Group Amy Webb joins Pioneers of AI host Rana el Kaliouby to unpack her 2026 Convergence Outlook and examin
Stop creating businesses. Buy one instead, with Codie Sanchez
Stop creating businesses. Buy one instead, with Codie Sanchez Sep 18, 2026 00:33:23 Own or be owned. That's Codie Sanchez's ultimatum for anyone serious about their financial future. The founder of Contrarian Thinking and author of the new book Own or Be Owned returns to Rapid Response to make her most impassioned case yet for why buying a small business is the most reliable path to wealth that most people are too scared to take. She breaks down what "cowboying" your bus
Let’s Kill Sh*t: Axios CEO on simplifying your work-life in the AI era
Let’s Kill Sh*t: Axios CEO on simplifying your work-life in the AI era Sep 15, 2026 00:32:51 AI isn't simplifying your life… Yet. It's mass-producing more options, more decisions, and more noise. Axios CEO Jim VandeHei returns to Rapid Response to make the case that the antidote isn't a better productivity app, it's a ruthless, three-part system he calls Confront, Delete, Amplify. VandeHei shares what he's learned from running Axios by these principles, including calling a leader
On's 16-year overnight success: Zendaya, Federer, and outrunning competition
On's 16-year overnight success: Zendaya, Federer, and outrunning competition Sep 11, 2026 00:27:07 On built a $4 billion sports brand in 16 years with a garden hose, a Roger Federer dinner in Zurich, and a young designer who watched a Halloween YouTube video. Co-founder and co-CEO David Allemann joins Rapid Response to explain why the defining decade for On is still ahead, and why being the most premium brand matters more than being the biggest. He breaks down the leadership shake-up t
NFL Kickoff: the science gets more damning, but the money keeps growing
NFL Kickoff: the science gets more damning, but the money keeps growing Sep 8, 2026 00:25:02 The NFL is the world's most valuable sports business, and it keeps growing. But is the growth sustainable? Sports journalist Michele Steele joins Rapid Response to kick off the 2026-2027 NFL season with a clear-eyed look at what's driving record franchise valuations, why quarterback salaries keep exploding, and what the league's dizzying array of streaming platforms means for the fans. Sh

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