Neurology Minute
The Neurology Minute podcast delivers a brief daily summary of what you need to know in the field of neurology, the latest science focused on the brain, and timely topics explored by leading neurologists and neuroscientists. From the American Academy of Neurology and hosted by Stacey Clardy, MD, Ph.D., FAAN, with contributions by experts from the Neurology journals, Neurology Today, Continuum, and more.
Episodes
The Relationship Between Age and Recovery After Spinal Cord Injury
Dr. Shuvro Roy and Prof. Catherine Jutzeler discussed how age influences neurologic and functional recovery after spinal cord injury and how these findings could inform treatment and future clinical trials. Show citation: Pavese C, Scivoletto G, Puci M, et al. The Relationship Between Age and Recovery After Spinal Cord Injury: A Longitudinal Cohort Study. Neurology. 2026;106(2):e214516. doi:10.1
Virtual vs In-Person Neurologic Ambulatory Care
Dr. Greg Cooper and Dr. Chloe Hill discuss comparing virtual and in-person neurology outpatient visits for new patients. Show citation: Hill CE, Lin CC, Harris A, et al. Virtual vs In-Person Neurologic Ambulatory Care: A Case-Control Study of Subsequent Health Care Utilization. Neurology. 2026;106(10):e214989. doi:10.1212/WNL.0000000000214989
Lab Minute: Tolosa Hunt Syndrome
In this lab minute, Dr. Stacey Clardy discusses Tolosa Hunt syndrome
Consortium of Neurology Residents and Fellows
Dr. Margarita Fedorova talks with Dr. Sunanjay Bajaj about the Consortium of Neurology Residents and Fellows (CNRF). Visit the AAN website to learn more about the CNRF. Connect with the AAN's Consortium of Neurology Residents and Fellows on Synapse.
Vamorolone for Duchenne Muscular Dystrophy
Dr. Aaron Zelikovich discusses the efficacy and anthropometric effect of vamorolone with prednisone and deflazacort. Show citation: Clemens PR, Berglund A, Schiava M, et al. Vamorolone for Duchenne Muscular Dystrophy: A Cross-Trial Efficacy Comparison With Classic Corticosteroids From the FOR-DMD Trial. Neurology. 2026;107(1):e214756. doi:10.1212/WNL.0000000000214756
American Epilepsy Society Clinical Practice Guideline - Part 1
In part one of this series, Dr. Dara Albert and Dr. Daniel Freedman share their key takeaways from the recent guideline. Show citation: Freedman D, Babatunde I, Morgan RL, et al. American Epilepsy Society Clinical Practice Guideline: Infantile Epilepsy. Epilepsy Curr. 2026;26(3):174-202. Published 2026 Apr 8. doi:10.1177/15357597261433266
Post-Traumatic Headache in Children and Genetic Risk of Migraine
Dr. Jessica Ailani and Dr. Serena Orr discuss the genetic risk of migraine and post-traumatic headache in children. Show citation: Orr SL, Hershey AD, Kurowski BG, et al. Post-Traumatic Headache in Children and Genetic Risk of Migraine: An Observational Cohort Study. Neurol Genet. 2026;12(2):e200371. Published 2026 Apr 1. doi:10.1212/NXG.0000000000200371
Efficacy and Safety of Cemdisiran siRNA in Myasthenia Gravis
Dr. Aaron S. Zelikovich discusses the phase 3 NIMBLE trial of cemdisiran, an siRNA targeting complement component 5, for the treatment of generalized myasthenia gravis. Show citation: Vu T, Habib AA, Jacob S, et al. Efficacy and safety of cemdisiran siRNA in myasthenia gravis (NIMBLE): a double-blind, randomised, placebo-controlled, phase 3 trial. Lancet. 2026;407(10540):1712-1725. doi:10.1016/S
Negative Myoclonus
Dr. Zohaib Siddiqi shares clinical pearls on negative myoclonus.
An Update on Troriluzole
Dr. Margarita Fedorova discusses the use of troriluzole for spinocerebellar ataxia. Show citations: https://www.neurology.org/doi/10.1212/WNL.0000000000209018 https://clinicaltrials.gov/study/NCT06034886 https://clinicaltrials.gov/study/NCT02960893
The Current State of Diagnostics for Neuroimmunologic Disorders in Africa
Drs. Paul Crane, Fiifi Duodu, and Malya Sahu discuss neuroimmunology and multiple sclerosis diagnosis in Africa, including challenges and efforts to improve care. Show citation: Sahu M, Chomba M, Duodu F, Diaz MM, Sokhi D, Saylor D. The Current State of Diagnostics for Neuroimmunological Disorders in Africa. J Cent Nerv Syst Dis. 2025;17:11795735251385319. Published 2025 Nov 19. doi:10.1177/1179
Ampreloxetine for Neurogenic Orthostatic Hypotension in MSA
Dr. Elizabeth Coon and Dr. Lucy Norcliffe-Kaufmann discuss the mechanism-based therapy with ampreloxetine for neurogenic orthostatic hypotension in multiple system atrophy, highlighting recent clinical trial results and future directions. Show citation: Freeman R, Kaufmann H, Biaggioni I, et al. Mechanism-Based Therapy With Ampreloxetine for Neurogenic Orthostatic Hypotension in Multiple System
Sex Differences in Levodopa Pharmacokinetics in Early Parkinson Disease
Dr. Margarita Fedorova explores sex-related differences in the pharmacokinetics of levodopa among levodopa-naïve patients with PD and evaluates their relationships with levodopa-related complications. Show citation: Conti V, De Bellis E, Corbi G, et al. Sex differences in levodopa pharmacokinetics in early Parkinson's disease: implications on levodopa-related complications. Front Pharmacol. 2026;
Psychiatric Comorbidities in Epilepsy - Part 2
In part two of this series, Dr. Halley Alexander and Dr. Heidi Munger Clary discuss the steps to take if you are screening for a psychiatric comorbidity and the results indicate that someone may be positive for depression, anxiety, or another condition. Show citations: Mula M, Brodie MJ, de Toffol B, et al. ILAE clinical practice recommendations for the medical treatment of depression in adults
August 2026 President Spotlight: How We're Working with the AMA
In the August episode of the President's Spotlight, Dr. Jason Crowell and Dr. Natalia Rost highlight how the AAN's growing representation within the AMA strengthens the voice of neurology. Stay informed by watching the President's Spotlight video.
Updates on BTK Inhibitors and Multiple Sclerosis Trials - Part 2
In part two of this series, Drs. Shuvro Roy, Jiwon Oh, and Amit Bar-Or discuss the results of the FENhance 1 and 2 trials looking at fenebrutinib in relapsing MS. For more information, please read about the abstract that was presented at the 2026 AAN Annual Meeting. Read more about the Fenebrutinib Trial.
Updates on BTK Inhibitors and Multiple Sclerosis Trials - Part 1
In part one of this series, Drs. Shuvro Roy, Jiwon Oh, and Amit Bar-Or discuss the results of the fenebrutinib trial and highlight the key takeaways that healthcare providers should be aware of. For more information, please read about the abstract that was presented at the 2026 AAN Annual Meeting. Read more about the Fenebrutinib Trial.
Psychiatric Comorbidities in Epilepsy - Part 1
In part one of this series, Dr. Halley Alexander and Dr. Heidi Munger Clary discuss the best methods for screening patients with epilepsy in a clinical setting. Show citations: Mula M, Brodie MJ, de Toffol B, et al. ILAE clinical practice recommendations for the medical treatment of depression in adults with epilepsy. Epilepsia. 2022;63(2):316-334. doi:10.1111/epi.17140 Patel AD, Baca C, Frankli
2026 International Conference on Functional Neurological Disorder - Part 2
In the second episode of this series, Dr. Dara Albert and Dr. Jon Stone discuss the future of FND and the innovative topics presented at the conference.
Exploring Military Sexual Trauma and Migraine Among US Veterans - Part 2
In part two of this series, Dr. Stacey Clardy and Dr. John Ney discuss what neurologists should do differently after reading this article. Show citation: Ney J, Fenton B, Grinberg AS, et al. Association of Military Sexual Trauma With Migraine and Migraine-Related Health Care Utilization Among Post-9/11 US Veterans. Neurol Clin Pract. 2026;16(3):e200618. doi:10.1212/CPJ.0000000000200618
2026 International Conference on Functional Neurological Disorder - Part 1
In the first episode of this series, Dr. Dara Albert and Dr. Jon Stone emphasize the main takeaway from this year's conference that should be taught to residents.
Exploring Military Sexual Trauma and Migraine Among US Veterans - Part 1
In the first part of this series, Dr. Stacey Clardy and Dr. John Ney discuss the key clinical messages for all practicing neurologists. Show citation: Ney J, Fenton B, Grinberg AS, et al. Association of Military Sexual Trauma With Migraine and Migraine-Related Health Care Utilization Among Post-9/11 US Veterans. Neurol Clin Pract. 2026;16(3):e200618. doi:10.1212/CPJ.0000000000200618
Lab Minute: Susac Syndrome and Behçet Disease
In this lab minute, Dr. Stacey Clardy discusses Susac syndrome and Behçet disease.
Lab Minute: Human Prion Disease
In this lab minute, Dr. Stacey Clardy discusses human prion disease.
Lab Minute: Human Prion Disease
In this lab minute, Dr. Stacey Clardy discusses human prion disease.
July 2026 President Spotlight: Mid-Year Update
In the July episode of the President's Spotlight, Dr. Jason Crowell and Dr. Natalia Rost provide a mid-year review of the AAN's progress, highlighting advocacy successes and the growing momentum for brain health worldwide. Stay informed by watching the President's Spotlight video.
Preparing ALS Clinics to Provide Longitudinal Care for Individuals Carrying ALS Risk Variants
Dr. Derek Stitt and Dr. Jennifer Morganroth discuss why identifying carrier status is so important. Show citation: Morganroth J, Yasek J, Harms M. Preparing Amyotrophic Lateral Sclerosis Clinics to Provide Longitudinal Care for Individuals Carrying ALS Risk Variants. Neurol Genet. 2026;12(4):e200406. Published 2026 Jun 24. doi:10.1212/NXG.0000000000200406
When Drug Marketing Masquerades as Clinical Trials
Dr. Justin Abbatemarco and Sukhun Kang discuss seeding trials and other hidden marketing tactics in clinical trials, and their implications for clinical practice and patient care. Show citation: Kang S, Lin I, Ekblom M, and Chang S. Clinical trials that are actually marketing ploys targeting doctors – how seeding trials put profit over patients. The Conversation. 2026;6(5). doi:10.64628/AAI.cxdf
The DRAIN Trial
Dr. Margarita Fedorova discusses the DRAIN trial and the efficacy of acetazolamide in idiopathic normal pressure hydrocephalus. Show citation: Virhammar J, Fasth O, Ekblom M, et al. Safety, tolerability, and efficacy of acetazolamide in idiopathic normal pressure hydrocephalus (DRAIN) in Sweden: a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Neurol. 2026;25(6):550-559. doi
Diagnosis and Management of Headache
Dr. Matthew Robbins discusses the assessment and diagnosis of headache in emergency settings, emphasizing red and green flags to differentiate primary from secondary headaches. This episode provides practical tips for trainees and clinicians to improve headache management. Show citation: Robbins MS. Diagnosis and Management of Headache: A Review. JAMA. 2021;325(18):1874-1885. doi:10.1001/jama.202
Navigating the Transition From Pediatric to Adult Epilepsy Care - Part 2
In the second episode of this series, Dr. Dara Albert and Dr. Scott Perry discuss common barriers to transitioning from pediatric to adult care and share practical strategies clinicians can use to support successful patient transitions. Show citation: Perry MS, Nascimento FA, Pina-Garza JE, et al. Addressing Barriers to Transitioning Pediatric Patients With Epilepsy to Adult Health Care in the Un
Neurology® at 75: The Evolution of the Neurology Journal
To celebrate 75 years of Neurology®, Dr. Chris Boes and Dr. José Merino discuss the journal's history, its evolution, and what lies ahead for the future of Neurology®. Read more about the first 75 years of Neurology®.
Navigating the Transition From Pediatric to Adult Epilepsy Care - Part 1
In part one of this series, Dr. Dara Albert and Dr. Scott Perry discuss what every neurology resident should know about caring for young adults with epilepsy as they transition from pediatric to adult neurology. Show citation: Perry MS, Nascimento FA, Pina-Garza JE, et al. Addressing Barriers to Transitioning Pediatric Patients With Epilepsy to Adult Health Care in the United States: A Narrative
June 22, 2026 Capitol Hill Report: Huge Milestone for Prior Authorization Bill
In this episode, Dr. Jonathan Crowe reviews the Capitol Hill Report from June 22nd, discussing milestones related to the Improving Seniors' Timely Access to Care Act. Stay updated with what's happening on the hill by visiting aan.com/chr. Learn how you can get involved with AAN advocacy.
Epilepsy Fundamentals Refresher Series - Part 3
In the third part of this series, Dr. Halley Alexander explores emerging trends and recent advances in epilepsy. Show citation: Tolchin B, Goldstein LH, Reuber M, et al. Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee. Neurology. 2026;106(1):e214466. doi:10.1212/WNL.0000000000214466 Hingray C, Popkirov S, Kozlowska K, et al. Func
Epilepsy Fundamentals Refresher Series - Part 3
In the third part of this series, Dr. Halley Alexander explores emerging trends and recent advances in epilepsy. Show citation: Tolchin B, Goldstein LH, Reuber M, et al. Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee. Neurology. 2026;106(1):e214466. doi:10.1212/WNL.0000000000214466 Hingray C, Popkirov S, Kozlowska K, et al. Func
Epilepsy Fundamentals Refresher Series - Part 2
In part two of this series, Dr. Halley Alexander discusses seizure types, epilepsy types, and the etiology of epilepsy. Show citations: Beniczky S, Trinka E, Wirrell E, et al. Updated classification of epileptic seizures: Position paper of the International League Against Epilepsy. Epilepsia. 2025;66(6):1804-1823. doi:10.1111/epi.18338 Beniczky S, Trinka E, Wirrell E, et al. A practical guide
Communication About Uncertainty During PD Diagnostic Consultations
Dr. Greg Cooper and Dr. Elisabeth Kurpershoek discuss how clinicians communicate uncertainty during Parkinson's disease diagnosis and how this impacts patient trust and understanding. Show citation: Hillen MA, Kurpershoek E, Huisman MHB, et al. Clinician Communication About Uncertainty During Parkinson Disease Diagnostic Consultations. Neurol Clin Pract. 2026;16(3):e200613. doi:10.1212/CPJ.00000
Comparing Sensitivity of Nerve Biopsy, Skin Biopsy, and Fat Aspirate in ATTRv-PN
Dr. Katie Krulisky and Dr. Marcus Pinto discuss the diagnosis and management of hereditary ATTR amyloidosis. Show citation: Panrudkevich AH, Jones FJS, Shouman K, et al. Sensitivity of Nerve and Skin Biopsy and Fat Aspirate for Amyloid in Symptomatic Hereditary ATTR Amyloidosis With Peripheral Neuropathy. Neurology. 2026;106(11):e218033. doi:10.1212/WNL.0000000000218033
Epilepsy Fundamentals Refresher Series - Part 1
In part one of this series, Dr. Halley Alexander explores epilepsy diagnosis. Previously posted Neurology Minute episodes related to epilepsy syndromes and their diagnosis. Show citation: Fisher RS, Acevedo C, Arzimanoglou A, et al. ILAE official report: a practical clinical definition of epilepsy. Epilepsia. 2014;55(4):475-482. doi:10.1111/epi.12550
Low Prevalence and Inconsistency of LRP4-IgG Detection in Suspected MG
Dr. Aaron Zelikovich discusses the frequency of LRP4-IgG in patients with suspected MG using different cell-based assay protocols. Show citation: Vacchiano V, Milano DC, Ricciardiello F, et al. Low Prevalence and Inconsistency of LRP4-IgG Detection in Suspected Myasthenia Gravis: A Multicenter CBA Comparison Neurology: Neuroimmunology & Neuroinflammation. 2026;13(3). doi:10.1212/NXI.000000000020
2026 European Stroke Organization Conference - Part 2
In part two of this series, Dr. Andy Southerland and Dr. Seemant Chaturvedi discuss the use of dual antiplatelet therapy with intravenous thrombolysis in patients with acute ischaemic stroke. Read more about the TAPIS trial.
2026 European Stroke Organization Conference - Part 1
In part one of this series, Dr. Andy Southerland and Dr. Seemant Chaturvedi discuss insights from the LATE-MT trial that was presented at the 2026 European Stroke Organization Conference. Read more about LATE-MT trial.
Safety and Efficacy of Satralizumab in Patients with Relapsing MOGAD
Dr. Shuvro Roy and Dr. Michael Levy discuss satralizumab for treating relapsing MOGAD, current management challenges, and the encouraging results of this new therapy. Read more about this abstract.
Safety and Efficacy of Adjunct Dexamethasone in Adults with Herpes Simplex Virus Encephalitis in The UK - Part 3
In part three of this series, Dr. Aaron Zelikovich discusses the clinical outcomes seen during and after the acute infection and how these findings can guide physicians in counseling their patients. Show citation: Solomon T, Hooper C, Easton A, et al. Safety and efficacy of adjunct dexamethasone in adults with herpes simplex virus encephalitis in the UK (DexEnceph): a multicentre, observer-blind
The Role of Social Media in Neurology Trainees' Professional Identity Formation - Part 2
In part two of this series, Dr. Jeff Ratliff and Dr. Gabriela Figueiredo Pucci discuss the lessons and experiences that happen in neurology-related social media interaction. Show citation: Pucci GF, Gheihman G, Albin CSW. Education Research: A Qualitative Analysis of the Role of Social Media in Neurology Trainees' Professional Identity Formation. Neurol Educ. 2026;5(2):e200307. Published 2026 Ap
Neurology Wait Times After Primary Care or Emergency Department Visits - Part 2
In part two of this series, Dr. Stacey Clardy and Dr. John Ney discuss the primary limitation of using claims data to estimate wait times for neurology services, particularly in rural areas or for subspecialty neurology care. Show citation: Laffargue EK, Van Der Goes DN, Wilson AM, Parziale SD, Sico JJ, Ney J. Neurology Wait Times After Primary Care or Emergency Department Visits Among the Commer
Neurology Wait Times After Primary Care or Emergency Department Visits - Part 2
In part two of this series, Dr. Stacey Clardy and Dr. John Ney discuss the primary limitation of using claims data to estimate wait times for neurology services, particularly in rural areas or for subspecialty neurology care. Show citation: Laffargue EK, Van Der Goes DN, Wilson AM, Parziale SD, Sico JJ, Ney J. Neurology Wait Times After Primary Care or Emergency Department Visits Among the Commer
The Role of Social Media in Neurology Trainees' Professional Identity Formation -Part 1
In part one of this two-part series, Dr. Jeff Ratliff and Dr. Gabriela Figueiredo Pucci shares the most important takeaway about professional identity formation among those actively engaged in neurology communities on social media. Show citation: Pucci GF, Gheihman G, Albin CSW. Education Research: A Qualitative Analysis of the Role of Social Media in Neurology Trainees' Professional Identity Fo
Neurology Wait Times After Primary Care or Emergency Department Visits - Part 1
In part one of this series, Dr. Stacey Clardy and Dr. John Ney break down the difference between mean and median wait times for new neurology appointments. Show citation: Laffargue EK, Van Der Goes DN, Wilson AM, Parziale SD, Sico JJ, Ney J. Neurology Wait Times After Primary Care or Emergency Department Visits Among the Commercially Insured Population in the United States: 2019-2023. Neurology.
Asundexian and OCEANIC-STROKE: A New Era in Stroke Prevention
Dr. Gillian L. Gordon Perue discusses asundexian and the OCEANIC-STROKE trial. Show citation: Sharma M, Dong Q, Hirano T, et al. Asundexian for Secondary Stroke Prevention. N Engl J Med. 2026;394(15):1467-1479. doi:10.1056/NEJMoa2513880
Acute Kidney Injury Related to Contrast Exposure
Dr. Madeline Russell discusses a common complication faced by patients with acute ischemic stroke. Show citation: Schwarz G, Cascio Rizzo A, Ambler G, et al. Contrast-Associated Acute Kidney Injury After Thrombectomy for Ischemic Stroke: Prognostic Impact and CAN-REST Predictive Score. Neurology. 2026;106(6):e214655. doi:10.1212/WNL.0000000000214655
Eptinezumab With Patient Education for Chronic Migraine and Medication-Overuse Headache
Dr. Bradley Ong discusses the use of eptinezumab in combination with patient education is an effective treatment for reducing disease burden in patients living with chronic migraine complicated by medication overuse. Show citation: Jensen RH, Lundqvist C, Schytz HW, et al. Eptinezumab With Patient Education for Chronic Migraine and Medication-Overuse Headache: The Randomized, Placebo-Controlled
Comparative Accuracy of TCD, TTE, TEE, and Cardiac CT for Detecting Right-to-Left Shunt in ESUS
Dr. Dan Ackerman and Dr. Reza Bavarsad Shahripour discuss the diagnostic performance of 4 major modalities: TCD, TTE, TEE, and cardiac CT in patients with embolic stroke of undetermined source. Sho citation: Read the related article in Neurology® Clinical Practice.
Miv-cel CD19 CAR T-Cell Therapy Shows Efficacy and Safety in Stiff Person Syndrome
Dr. Shuvro Roy and Dr. Amanda Piquet discuss a brief overview of stiff person syndrome, as well as the trial and the trial results. Read more about this abstract on the AAN website. Show transcript: Dr. Shuvro Roy: Hi, this is Shuvro Roy from the University of Washington and welcome to today's Neurology Minute. I just wrapped a longer conversation with Amanda Piquet from the University of Colo
Miv-cel CD19 CAR T-Cell Therapy Shows Efficacy and Safety in Stiff Person Syndrome
Dr. Shuvro Roy and Dr. Amanda Piquet discuss a brief overview of stiff person syndrome, as well as the trial and the trial results. Read more about this abstract on the AAN website. Show transcript: Dr. Shuvro Roy: Hi, this is Shuvro Roy from the University of Washington and welcome to today's Neurology Minute. I just wrapped a longer conversation with Amanda Piquet from the University of Colo
Understanding Rett Syndrome - Part 4
In the fourth episode of this series, Dr. Stacey Clardy discusses care team essentials and working within multidisciplinary teams. Show transcript: Dr. Stacey Clardy: This is the Neurology Minute. I'm Stacey Clardy from the Salt Lake City VA and the University of Utah. This is our 4th episode in our four-part series on Rett syndrome. Today we're going to discuss care team essentials and working
Lab Minute: MTHFR
Dr. Stacey Clardy discusses methylenetetrahydrofolate reductase (MTHFR) in this lab minute. Show transcript: Dr. Stacey Clardy: Hi, this is Stacey Clardy from the Salt Lake City VA in the University of Utah. Let's do a lab minute today on MTHFR. This one just simply will not go away. This is one of those topics where a huge amount of patient anxiety is inversely proportional to the utility of a
June 2026 President Spotlight: Community at the AAN
In the June episode of the President's Spotlight, Dr. Jason Crowell and Dr. Natalia Rost discuss the sense of community present within the AAN. Stay informed by watching the President's Spotlight video. Show transcript: Dr. Jason Crowell: This is Jason Crowell with today's Neurology Minute. Once again, this month for our presidential spotlight, we have Natalia Rost joining us. Natalia, thanks
New Resident Guide to Stroke Alerts - Part 2
In part two of this series, Dr. Andy Southerland and Dr. Dan Ackerman discuss a few rapid‑fire concepts from the 2026 guidelines, focusing on what is new and how emerging data may shape patient care. Show transcript: Dr. Andy Southerland: Hello, everyone. This is Andy Southerland from the University of Virginia. And for today's Neurology Minute, I'm speaking with my friend and colleague, Dan Ack
New Resident Guide to Stroke Alerts - Part 1
In part one of this series, Dr. Andy Southerland and Dr. Dan Ackerman discuss what stands out in the latest thrombolysis guidelines, how these decisions are applied in stroke center practice, and how to educate residents and fellows on incorporating new evidence into treatment choices. Show transcript: Dr. Andy Southerland: Hi. This is Andy Southerland from the University of Virginia, and for toda
Understanding Rett Syndrome - Part 3
In the third episode of this series, Dr. Stacey Clardy discusses treatment options and ongoing management. Show transcript: Dr. Stacey Clardy: This is The Neurology Minute. I'm Stacey Clardy from the Salt Lake City VA at the University of Utah. This is the third episode today in our four-part series on Rett syndrome, and we're going to talk about treatment options and ongoing management. There is
Shunting for Idiopathic Normal Pressure Hydrocephalus
Dr. Margarita Fedorova discusses the effectiveness of shunting for idiopathic normal pressure hydrocephalus. Show citation: Luciano MG, Williams MA, Hamilton MG, et al. A Randomized Trial of Shunting for Idiopathic Normal-Pressure Hydrocephalus. N Engl J Med. 2025;393(22):2198-2209. doi:10.1056/NEJMoa2503109 Show transcript: Dr. Margarita Fedorova: Welcome to Neurology Minute. My name is Marg
Recent Updates in Central Retinal Artery Occlusions
Dr. Casandra MacLeod discusses central retinal artery occlusions, recent trials, and those anticipated in the future. Show citation: Préterre C, Gaultier A, Obadia M, et al. Intravenous alteplase versus oral aspirin for acute central retinal artery occlusion within 4·5 h of severe vision loss (THEIA): a multicentre, double-dummy, patient-blinded and assessor-blinded, randomised, controlled, phas
Prion Disease Clinical Trial NN112
Dr. Gregg Day and Drs. Sonia Vallabh and Eric Minikel discuss scientific insights and the future of prion disease treatment, highlighting the importance of early diagnosis, personalized medicine, and hope for affected families. Learn about the clinical trial. Learn more about the Prion Alliance. Show transcript: Dr. Gregg Day: This is Gregg Day with Neurology Minute. I've just been speaking w
Headache Medicine Highlights from the 2026 AAN Annual Meeting - Part 2
In the second episode of this series, Dr. Tesha Monteith and Dr. Peter Goadsby discuss the prediction of treatment responses for personalized medicine. Show transcript: Dr. Tesha Monteith: Hi, this is Tesha Monteith with The Neurology Minute. Today I'm speaking with Peter Goadsby from the Division of Biomedical Sciences at King Abdullah University of Science and Technology about key trends in hea
Understanding Rett Syndrome - Part 2
In the second episode of a four-part series on Rett syndrome, Dr. Stacey Clardy discusses the importance of early referrals, particularly during the regression phase. Show transcript: Dr. Stacey Clardy: This is the Neurology Minute. I'm Stacey Clardy from the Salt Lake City VA and the University of Utah. This is the second episode in a four-part series on Rett syndrome. Today, let's discuss whe
Lower Risk of Dementia with AS01-Adjuvanted Vaccination Against Shingles and Respiratory Syncytial Virus Infections
Dr. Margarita Fedorova discusses whether a vaccine ingredient is quietly protecting the brain. Show citation: Taquet M, Todd JA, Harrison PJ. Lower risk of dementia with AS01-adjuvanted vaccination against shingles and respiratory syncytial virus infections. NPJ Vaccines. 2025;10(1):130. Published 2025 Jun 25. doi:10.1038/s41541-025-01172-3 Show transcript: Dr. Margarita Fedorova: Welcome to N
Humoral Vaccine Responses and One-year Follow-up of Infants Potentially Exposed to Ocrelizumab During Pregnancy and Breastfeeding - Part 3
In the final episode of this series, Dr. Justin Abbatemarco and Dr. Ruth Dobson discuss navigating conversations with women and their families about potential ocrelizumab exposure during pregnancy and breastfeeding. Read more about this abstract on the AAN website. Show transcript: Dr. Justin Abbatemarco: Hello and welcome back. This is Justin Abbatemarco on our final episode with Ruth Dobson f
Headache Medicine Highlights from the 2026 AAN Annual Meeting - Part 1
In the first part of this series, Dr. Tesha Monteith and Dr. Peter Goadsby discuss some major themes that emerged from the AAN Annual Meeting regarding headache medicine.
Inflammation, Limbic White Matter, and Symptoms After Repetitive Head Impacts in Retired Football Players
Dr. Alex Menze and Dr. Breton Asken discuss the long-term impacts of repetitive head impacts in football players, focusing on inflammation, brain microstructure, and cognitive decline. Show citation: Emanuel OM, Miner AE, Lee SY, et al. Inflammation, Limbic White Matter Microstructure, and Clinical Symptoms in Retired American Football Players With Repetitive Head Impacts. Neurology. 2026;106(6):
Understanding Rett Syndrome - Part 1
In the first episode of a four-part series, Dr. Stacey Clardy discusses the diagnosis and clinical presentation of Rett syndrome.
Humoral Vaccine Responses and One-year Follow-up of Infants Potentially Exposed to Ocrelizumab During Pregnancy and Breastfeeding - Part 2
In part two of this series, Dr. Justin Abbatemarco and Dr. Ruth Dobson discuss the main findings of this study. Read more about this abstract on the AAN website.
Humoral Vaccine Responses and One-year Follow-up of Infants Potentially Exposed to Ocrelizumab During Pregnancy and Breastfeeding - Part 1
In part one of this series, Dr. Justin Abbatemarco and Dr. Ruth Dobson discuss current evidence on monoclonal antibodies in pregnancy and breastfeeding and prior understanding of CD20 therapies. Read more about this abstract on the AAN website.
Updates Regarding Radiation Necrosis - Part 1
Dr. Justin Abbatemarco and Dr. Kait Nevel discuss tips and tricks for managing radiation necrosis in hospitals and outpatient settings. Show transcript: Dr. Justin Abbatemarco: Hello, and welcome. This is Justin Abbatemarco, and I just finished interviewing Kate Neville about radiation necrosis following radiosurgery. Kait is a neuro-oncologist at Indiana University. Kait, maybe we could just st
Association of Changes in Activity Patterns With Brain Atrophy and Disability Progression in People With MS
Dr. Alex Menze and Dr. Kathryn C. Fitzgerald discuss using accelerometry to detect subtle, longitudinal changes in disability in people with multiple sclerosis and how these changes relate to brain atrophy and disability progression. Show citation: Fitzgerald KC, Sanjayan M, Dewey BE, et al. Association of Changes in Activity Patterns With Brain Atrophy and Disability Progression in People With
Clinical Heterogeneity and Candidate Biomarkers in POLG-Related Mitochondrial Disease - Part 2
In the second part of this series, Dr. Katie Krulisky and Dr. Cristina Domínguez-González explore the most effective approach to evaluating suspected mitochondrial disease. Show citation: Bermejo-Guerrero L, Restrepo-Vera JL, Martin-Jimenez P, et al. Clinical Heterogeneity and Candidate Biomarkers in POLG-Related Mitochondrial Disease. Neurol Genet. 2026;12(2):e200365. Published 2026 Mar 10. doi:1
Workplace Lactation in Neurology: Barriers and Opportunities - Part 2
In the last episode of the series, Dr. Stacey Clardy and Drs. Deborah Hall and Deborah Setter discuss some practical changes that can immediately improve lactation support in neurology workplaces. Show transcript: Dr. Stacey Clardy: This is the Neurology Minute. I'm Stacey Clardy from the Salt Lake City VA and the University of Utah. I've just had a fantastic in depth podcast discussion with Debo
May 2026 President Spotlight: AAN Annual Meeting Update
In the May episode of the President's Spotlight, Dr. Jason Crowell and Dr. Natalia Rost provide a leadership perspective on the 2026 Annual Meeting. Stay informed by watching the President's Spotlight video. Show transcript: Dr. Jason Crowell: Hey, this is Jason Crowell with today's Neurology Minute. Once again, we have Natalia Rost joining us for our monthly check-in. Of course, Natalia is th
Clinical Heterogeneity and Candidate Biomarkers in POLG-Related Mitochondrial Disease - Part 1
In part one of this series, Dr. Katie Krulisky and Dr. Cristina Domínguez-González discuss when a neurologist should start thinking about mitochondrial disease. Show citation: Bermejo-Guerrero L, Restrepo-Vera JL, Martin-Jimenez P, et al. Clinical Heterogeneity and Candidate Biomarkers in POLG-Related Mitochondrial Disease. Neurol Genet. 2026;12(2):e200365. Published 2026 Mar 10. doi:10.1212/NXG.
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Becoming: HER with Nikki Spoelstra
