REBEL Cast
REBEL Cast is a medical podcast that focuses on rational, evidence-based evaluation of literature. Hosted by Dr. Salim R. Rezaie, it aims to critically appraise and discuss recent studies and clinical practices in emergency medicine and critical care.
Episodes
REBEL MIND – Human Factors: The Hidden Architecture of Emergency & Critical Care Medicine
🧭 REBEL Rundown
🔑 Key Points
🧩 Human Factors: The unseen behaviors, distractions and considerations critical in emergency medicine and the ICU, influencing patient care beyond just medical k
REBEL MIND – The Mental Jump: Moving from Junior to Senior Leadership in Emergency Care
🧭 REBEL Rundown
📌 Key Points
Parallel Tasking: Transitioning from junior to senior roles in medicine involves both personal growth and the development of leadership skills, often simultaneously.
P
REBEL MIND – Growth vs Fixed Mindset in Medicine
🧭 REBEL Rundown
🔑Key Points
🌱 Growth mindset transforms learning – Residents and students who believe skills can be developed are more open to feedback, more resilient after failure,
Diastology: Use E/e’ to Estimate Left Atrial Pressure
🧭 REBEL Rundown
📌 Key Points
🎯 POCUS diastology answers one ED question: Is left atrial pressure (LAP) elevated right now? (not “diagnose diastolic dysfunction”)📈 E/e&#
REBEL MIND – How to Sleep When the World Says You Can’t
🧭 REBEL Rundown
🔑Key Points
Try the coffee nap! Where you combine caffeine and a 30-minute nap to then have that boost energy and alertness by the time it kicks in.💤 Sleep isn’t optio
REBEL MIND: Applying Performance Science In and Out of the Emergency Department
🧭 REBEL Rundown
📌 Key Points
🔍 Understanding the Why: The significance of understanding underlying causes, beyond initial diagnoses, in both sports and emergency medicine is explored. ȿ
REBEL Core Cast 150.0: Emergency Medicine Consults: How to Call a Consult + Handle Pushback (With Scripts)
🧭 REBEL Rundown
📌 Key Points
The 4 Steps of an ED Consult:👋 Introduce yourself and your role🎯 Lead with the outcome (the ask)🧾 Give a focused case summary (why it’s th
REBEL CAST – RENOVATE Trial: HFNC vs BPAP in Acute Respiratory Failure
🧭 REBEL Rundown
📌 Key Points
💨 HFNC met criteria for non-inferiority to BPAP for preventing intubation or death within 7 days in four of the five ARF subgroups.🧪 Bayesian dynamic bor
REBEL MIND – Rest Is Not Sleep: The Seven Dimensions of True Recovery
🧭 REBEL Rundown
🔑Key Points
🛌 Rest isn’t a luxury; it’s a necessity and differs significantly from sleep in terms of mental and physical recovery needs.🧠 Uncovering the s
REBEL Core Cast 149: Review of Corticosteroids in Community-Acquired Pneumonia
🧭 REBEL Rundown
🗝️ Key Points
💉 Hydrocortisone Saves Lives:The 2023 Cape Cod Trial (NEJM) showed a clear mortality benefit and reduced need for intubation in severe CAP patients treat
REBEL CAST – IncrEMentuM26 Speaker Spotlight : Drs. Sara Crager and Ryan Ernst
🧭 REBEL Rundown
📝Introduction
Welcome to this special edition of the REBEL Cast, where we unravel key highlights and educational insights from the IncrEMent
REBEL MIND: The Power of Performance Coaching in Medicine
🧭 REBEL Rundown
📌 Key Points
💪 Building Resilience: Rebel MIND, in partnership with Arena Labs, introduces a science-based performance coaching platform specifically tailored for healthcare
REBEL MIND: Performance Under Pressure – What Medicine Can Learn from Elite Teams
🧭 REBEL Rundown
📌 Key Points
🎯Partnership Focus: New collaboration with Arena Labs aimed at enhancing healthcare worker wellness.🏃🏽‍️‍➡️Per
REBEL Core Cast 148.0–Demystifying Non-Invasive Ventilation & HiFlow
🧭 REBEL Rundown
🗝️ Key Points
💨 NIV = Support without a tube: CPAP, BiPAP, and HFNC improve oxygenation and reduce the work of breathing.🫁 CPAP = Continuous pressure: Best for
The RSI Trial: Ketamine vs Etomidate in Rapid Sequence Intubation
🧭 REBEL Rundown
📌 Key Points
💀 Mortality: No statistically significant difference in 28-day mortality between ketamine vs etomidate for intubation in critically ill patients, though there wa
REBEL MIND – The Dunning Kruger Effect: Why Looking Inward Improves Patient Care
🧭 REBEL Rundown
📌 Key Points
🧠 We don’t know what we don’t know: Low experience can inflate confidence; true expertise usually brings humble certainty.🏥 ED relevance is
REBEL Core Cast 147.0–Ventilators Part 5: Key Mechanical Ventilator Pressures & Definitions Made Simple
🧭 REBEL Rundown
🗝️ Key Points
💨 Peak vs. Plateau Pressures: PIP reflects total airway resistance and compliance, while Pplat isolates alveolar compliance—elevations in both sug
REBEL Core Cast 146.0–Ventilators Part 4: Setting up the Ventilator
🧭 REBEL Rundown
🗝️ Key Points
❌ Don’t chase perfect numbers: Adequate and safe is often better than “perfect but harmful.”💨 Oxygenation levers: Start with
REBEL Core Cast – Pediatric Respiratory Emergencies: Beyond Viral Season
🧭 REBEL Rundown
📝 Introduction
Welcome to the Rebel Core Content Blog, where we delve into crucial knowledge for emergency medicine. Today, we share insightful tips from PEM specialist Dr. Elise Per
REBEL CAST – IncrEMentuM26 Speaker Spotlight : Drs. Tarlan Hedayati, Jess Mason and Simon Carley
🧭 REBEL Rundown
📝Introduction
Welcome to this special edition of the REBEL Cast, where we unravel key highlights and educational insights from the IncrEMent
REBEL Core Cast 145.0: Understanding QTc Prolongation: Causes, Risks, and Management
🧭 REBEL Rundown
📌 Key Points
🫀 Prolonged QTc raises risk of torsades de pointes ⏱️ Correct for heart rate: QTc > 440 ms (men) or > 460 ms (women); > 500 ms = high TdP
REBEL Core Cast 144.0: Tourniquet Tips
🧭 REBEL Rundown
📌 Key Points
🩸 Tourniquets save lives and limbs: Apply immediately when you’ve got arterial bleeding.📍 Placement matters: Position the tourniquet 5–6 cm
REBEL CAST – IncrEMentuM26 Speaker Spotlight : George Willis and Mark Ramzy
🧭 REBEL Rundown
📝Introduction
In this exciting episode of REBEL Cast, host Dr. Mark Ramzy joins forces with renowned educator and speaker, Dr. George Willis
REBEL Core Cast – DKA: Beyond the Basics Part 2 – SCOPE DKA-Trial
🧭 REBEL Rundown
🔑Key Points
💧 Fluid Choice Matters: Plasma-Lyte, a balanced crystalloid, corrected acidosis faster than normal saline in severe DKA patients, with no increase in adverse even
REBEL Core Cast – DKA: Beyond the Basics Part 1 – The SQuID Protocol
🧭 REBEL Rundown
🗝️ Key Points
🛏️ Fewer ICU AdmissionsOnly 5 patients in the SQuID group required ICU care vs 99 in the traditional insulin drip group.⏱️ Shorter E
REBEL Core Cast 143.0–Ventilators Part 3: Oxygenation & Ventilation — Mastering the Balance on the Ventilator
🧭 REBEL Rundown
🗝️ Key Points
❌ Don’t chase perfect numbers: Adequate and safe is often better than “perfect but harmful.”💨 Oxygenation levers: Start with
REBEL Core Cast 142.0–Ventilators Part 2: Simplifying Mechanical Ventilation – Most Common Ventilator Modes
🧭 REBEL Rundown
🗝️ Key Points
💨 Start with Breath Types: Controlled, assisted, and supported breaths are the foundation of all modes.🛌 Comfort Over “Best Mode”:
Incrementum Conference 2026: Revolutionizing Emergency Medicine in Spain
🧭 REBEL Rundown
Click here for Direct Download of the Podcast.
⏰ Highlights
00:00 Introduction to Rebel Cast00:10 Highlighting the Incrementum Conference 202600:3
REBEL Core Cast 141.0–Ventilators Part 1: Simplifying Mechanical Ventilation — Types of Breathes
🧭 REBEL Rundown
🗝️ Key Points
💨 Master the 3 Types of BreathsControl, Assist, and Spontaneous — know the difference before tackling ventilator modes.📦 Breath Delivery:
REBEL Core Cast 140.0: The Power and Limitations of Intraosseous Lines in Emergency Medicine
🧭 REBEL Rundown
📌 Key Points
💉 IO Lines Are Life-Saving in Extremis: IO access is fast, reliable, and can deliver nearly any resuscitative medication or fluid during cardiac arrest or hemorr
REBEL Core Cast 139.0: Pneumothorax Decompression
🧭 REBEL Rundown
📌 Key Points
🧠 Think Beyond Trauma: Don’t forget to suspect tension pneumothorax in ventilated patients who suddenly crash or after a central line placement! 🫁
REBEL Core Cast 138.0: A Simple Bedside Approach to Shock
🧭 REBEL Rundown
📌 Key Points
🧠 Shock is a Clinical Diagnosis — Not Just a NumberPatients can be in compensated shock with normal BP. Look for signs like AMS, cool extremities, ↓
REBEL Core Cast 137.0: A Simple Approach to Sinus Tachycardia
🧭 REBEL Rundown
📌 Key Points
🩺 Sinus Tachycardia = Clinical Clue: Don’t just treat the number—it’s a sign of underlying physiologic stress.🧮 Oxygen Delivery Equat
REBEL Core Cast 136.0: A Simple Approach to the Tachypneic Patient
🧭 REBEL Rundown
📌 Key Points
Short + shallow: Neuromuscular, bronchospasm, or compliance problem → act fast ⚠️Normal/large tidal volume: Compensation for metabolic/systemic
REBEL Core Cast 135.0: A Simple Approach to Hypoxemia (vs. Hypoxia)
🧭 REBEL Rundown
📌 Key Points
🫁 Hypoxemia = low blood oxygen🧠 Hypoxia = low tissue oxygen🔍 5 causes of hypoxemia, but most hospital cases are either:🚫 Shunt = doesn&#x
REBEL Core Cast 134.0 – Acetaminophen Toxicity
Acetaminophen (APAP) overdose remains one of the most common causes of acute liver failure in the United States. While its therapeutic use is widespread and generally safe, unintentional overdoses and delayed presentations can lead to devastating outcomes. In this episode of REBEL Cast, we break down the pathophysiology, clinical course, diagnostic approach, and evidence-based management of APAP
Street Medicine: Compassionate Care for the Unhoused
Introduction: In this episode of Rebel Cast, host Marco Propersi, along with co-hosts Steve Hochman and Kim Baldino, delve into the practice and importance of street medicine—the direct delivery of healthcare to homeless and unsheltered individuals. Special guests Dr. Jim O’Connell, a pioneer of street medicine, and Dr. Ed Egan, a recent street medicine fellowship graduate, share the
REBEL Core Cast 131.0 – Traumatic Arthrotomy
Take Home points:
Always suspect an open joint if there is a laceration, regardless of size, the lies over joint
CT scan of the affected joint is widely considered to be the standard approach to evaluation but the saline load test may be useful in certain circumstances.
Obtain emergency orthopedics consultation for all open joints and administer antibiotics and update tetanus in all patients
&#x
REBEL Core Cast 130.0 – Omphalitis
Take Home Points
Early diagnosis: erythema and warmth of the skin surrounding the umbilicus isn’t normal. Get labs, start abx and get the patient admitted
Consult peds surgery on all of these patients as progression to nec fast, while uncommon, is devastating
If the patient appears toxic or has systemic symptoms, the simply omphalitis has progressed and aggressive treatment including surge
REBEL Core Cast 129.0 – Gastric Lavage
Take Home Points
Orogastric lavage may still play an important role in treatment of the overdose patient.  Do not perform lavage if the ingestion has limited toxicity at any dose or the ingested dose is unlikely to cause significant toxicity.
Strongly consider orogastric lavage in a patient who has taken an overdose of drugs that are particularly toxic, suspected extreme doses associated wit
REBEL Core Cast 128.0 – Toxic Alcohols
Take Home Points
Toxic alcohols generally refer to methanol and ethylene glycol as these substances pose significant metabolic derangement and end-organ damage.
Patient who present shortly after ingestion will simply look inebriated – no different than ethanol intoxication. At this point, patients will have an elevated osmolar gap and little to no anion gap.
Patient who presents in a delaye
REBEL Core Cast 127.0 – Penetrating Neck Injuries
Take Home Points
Anticipate anatomically challenging airways and consider early intubation prior to loss of airway anatomy.
Skip the zones of the neck and focus on hard signs of vascular (Shock w/o another source, Pulsatile bleeding, Expanding hematoma, Audible bruit, Signs of stroke) or aerodigestive (Airway compromise, Bubbling wound, Extensive SubQ air, Stridor, Significant hemoptysis/hemateme
A Winning Hand in Cardiology: Queen of Hearts AI Model Enhances OMI Detection
Background: Cath lab activation based on ST-elevation myocardial infarction (STEMI) criteria is founded on aging data and requires evolution. In the “Occlusive Myocardial Infarction (OMI) Manifesto,” emergency physicians Dr. Steve Smith, Dr. Pendell Meyers, and Dr. Scott Weingart introduced a new paradigm —OMI vs. non-occlusive myocardial infarction (NOMI).
The OMI/NOMI paradi
REBEL Core Cast 126.0 – Peds Hem Onc Emergencies
Take Home Points
Early administration of antibiotics (within 60 min) in patients with fever and neutropenia is life saving.
Fever in sickle cell is an emergency and always requires cultures and antibiotics even if the child appears well.
Avoid sedation and lying supine and steroids in patients with mediastinal masses.
Red flags in patients with headaches that may suggest a brain tumor  inclu
REBEL Core Cast 125.0 – Hyperkalemia
Take Home Points
Always obtain an EKG in patients with ESRD upon presentation
Always obtain an EKG in patients with hyperkalemia as pseudohyperkalemia is the number one cause
If the patient with hyperkalemia is unstable or has significant EKG changes (wide QRS, sine wave) rapidly administer calcium salts
In patients who are anuric, early mobilization of dialysis resources is critical
REBEL Co
REBEL Core Cast 124.0 – Hyperinsulinemia Euglycemia Therapy
Take Home Points
Management of severe beta-blocker and calcium-channel blocker toxicity should occur in a stepwise fashion: potential gastric decontamination, multiple lines of access, judicious fluids, calcium, glucagon, and vasopressors as needed.
Initiation of high dose insulin therapy requires a tremendous amount of logistical and cognitive resources as it requires cross-disciplinary collabor
REBEL Core Cast 123.0 – Posterior Epistaxis
Take Home Points:
Posterior epistaxis is a rare, life-threatning presentation.
The key is in identifying and rapidly gaining control with a posterior pack or foley catheter.
These patients often require surgical intervention so get ENT to the bedside and admit to a place with a higher level of monitoring.
REBEL Core Cast 123.0 – Posterior Epistaxis
Click here for Direct Download of th
ANNEXA-1: Andexanet Alfa Associated with Harm in DOAC Reversal
Background: In May of 2018, Andexanet alfa gained accelerated approval by the FDA for the reversal direct oral anticoagulants (DOACs) despite a lack of robust evidence for use. The 2022 AHA/ASA guidelines give the drug a level 2A recommendation and recommend it over the use of 4F-PCC (Greenberg 2022). FDA approval alongside guideline endorsement has led to the drug seeing a remarkable growth in us
REBEL Core Cast 122.0 – Neutropenic Fever
Take Home Points:
There are many causes of neutropenia, chemotherapy being by far the most dangerous.
Febrile neutropenia is a condition conveying high mortality. Early administration of antibiotics is the only factor known to reduce this mortality.
For a patient with neutropenic fever, remember that the body’s own flora is the greatest danger. Isolate, but do not wait to initiate treatmen
REBEL Cast Ep126: Should We Not Be Recommending Small Adult BVMs in OHCA?
Background: The holy grail of outcomes in OHCA is survival with good neurologic outcome.  The only interventions proven to increase this outcome are high quality CPR and defibrillation in shockable rhythms.  Ventilation is also an important component of resuscitation in OHCA.  Excess minute ventilation can adversely affect hemodynamics due to increased intrathoracic pressure (i.e.
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