The Myeloma Minutes
A living library of credible information for patients of multiple myeloma and their caregivers. The podcast features discussions with experts and patients to provide reliable insights into the disease, treatment options, and supportive care. It aims to empower listeners with knowledge to navigate their myeloma journey.
Episodes
043 The PERSEUS Regimen: A New Era in Myeloma Treatment
This episode explores the latest advances in myeloma treatment, explaining how the PERSEUS regimen combines four drugs, stem cell transplant and personalised maintenance to help patients achieve deeper, longer-lasting remissions.📌Key Takeaways: Could remission last 10 years or more? Four drugs, better results - what has changed? Side effects matter: why your treatment can be adjusted.
042 Frailty and Myeloma: Is Age Really Just a Number?
Could the right treatment pace make all the difference to living well with myeloma? Professor Gordon Cook explores frailty in myeloma, explaining why it is more than age, how fitness can change during treatment, and why treatment should be tailored to the individual.📌Key Takeaways: Frailty is dynamic - it can change. Age alone doesn't tell the whole story. Myeloma treatment isn't a spri
041 What are Plasmacytomas
This episode explores the realities of living with multiple myeloma, from treatment and managing symptoms to maintaining quality of life and finding confidence beyond the diagnosis. 📌Key Takeaways: Myeloma changes life - but it doesn’t have to define it. Small changes can make a big difference to wellbeing. You can still plan, adapt and look forward.For extra content and more resources,
040 From the Conference Floor: The Latest Advances in Myeloma Care
This episode explores the latest breakthroughs from the world's leading myeloma conferences, explaining how new research and clinical trials could shape future treatment and improve patient care with Charlotte.📌Key Takeaways: Discover the newest treatments that could transform myeloma care in the years ahead. Find out why clinical trials today become tomorrow’s standard treatments. Hear
039 DT-PACE Explained: When Myeloma Needs a Different Approach
This episode explains when DT-PACE chemotherapy is used in myeloma, how it works, what patients can expect during treatment, and why it remains an important bridge to newer therapies.📌Key Takeaways: Why use older chemotherapy? Sometimes it's the fastest way to get myeloma back under control. DT-PACE is a bridge - helping patients reach treatments like stem cell transplant or CAR T-cell t
038 A New Four-Drug Treatment for Myeloma: What Does DVRD Mean for Patients?
Experts discuss the approval of the new DVRD four-drug treatment for newly diagnosed myeloma patients who are not eligible for a stem cell transplant, exploring its benefits, risks and how treatment decisions are personalised.📌Key Takeaways: New four-drug treatment now available in England and Wales Deeper remissions and longer disease control for many patients Why the “best” treatment d
037 From Patient to Author: Jonathan Gluck’s Myeloma Story
Author Jonathan Gluck shares his deeply personal experience of living with myeloma, reflecting on diagnosis, uncertainty, treatment, resilience and what it means to build a life alongside cancer.📌Key Takeaways: How do you live with uncertainty? Jonathan shares the lessons myeloma taught him. A diagnosis can change your life - but it doesn’t have to define it. One patient’s story of resi
036 Infection and Myeloma - Staying Safe Without Stopping Life
This episode explores why people with myeloma are more vulnerable to infection, how treatments affect immunity, and the practical steps patients and carers can take to stay well.📌Key Takeaways:Myeloma and its treatments can weaken the immune system - but the risk changes over time. Fever, coughs or feeling “not quite right” should never be ignored - early treatment matters.From vaccines t
035 Blood Clots and Myeloma - What Every Patient Should Know
This episode explains why people with myeloma are at higher risk of blood clots, how blood thinners help, and the warning signs patients and carers should never ignore.
📌Key Takeaways:
Myeloma and some myeloma treatments can increase the risk of dangerous blood clots.
Simple steps like staying hydrated, keeping mobile and taking blood thinners correctly really matter.
Leg swelling, chest
034 Pain in Myeloma - Understanding It and Taking Back Control
This episode explores why pain happens in myeloma, how it affects daily life, and the many ways it can be managed - from painkillers to specialist support.
📌Key Takeaways:
Myeloma pain is common - but it can almost always be improved with the right approach.
Pain relief isn’t just tablets - treatments, radiotherapy and targeted procedures all play a role.
Uncontrolled pain affects everyt
033 MRD Explained: How Much Myeloma Is Really Left
This episode explains minimal residual disease (MRD) - what it is, how it’s measured, and how it could shape more personalised myeloma treatment in the future.
📌Key Takeaways:
Even when blood tests look ‘normal’, tiny amounts of myeloma can still remain - MRD helps find it.
Reaching MRD negativity is a powerful sign - it often means longer, deeper remission.
In the future, MRD could deci
032 What Do My Blood Results Mean? - A Myeloma Guide
This episode breaks down common blood test results in myeloma, helping patients and carers understand what the numbers mean, what matters most, and when to worry (and when not to).
📌Key Takeaways:
Not all ‘red’ results are bad - trends over time matter more than a single number.
Three key numbers to watch: haemoglobin, neutrophils and platelets.
Blood tests are your roadmap - guiding tre
031 Living Young with Myeloma: Treatment, Relapse and a Breakthrough with CAR-T
Meera shares her powerful 15-year journey with multiple myeloma — from diagnosis during pregnancy to stem cell transplant, maintenance therapy and ultimately CAR-T treatment leading to remission.
📌Key Takeaways:
CAR-T can work fast! Mira’s light chains became undetectable within weeks.
Relapse doesn’t mean the end of options: new treatments are changing what’s possible.
You are not alo
030 CAR-T Therapy Explained: A Personalised Treatment for Myeloma
In this episode Doctors Jam & Sally explain CAR-T cell therapy for myeloma - how it works, what the treatment journey looks like, the potential side effects, and why it offers hope for longer treatment-free time.
📌Key Takeaways:
Your own immune cells can be re-engineered to find and destroy myeloma - a truly personalised treatment.
After CAR-T, many patients can have months or years
029 Belantamab Returns: A New Combination for First Relapse Myeloma
This episode explains the new NICE-approved combination of belantamab, pomalidomide and dexamethasone for people whose myeloma has relapsed after first-line treatment, including benefits, side effects and how treatment decisions are made.
📌Key Takeaways:
This new combination can keep myeloma under control for nearly three years after first relapse.
Eye side effects are common but closely
028 Myeloma in 2026 - What's Coming Next and Why It Matters
This episode looks ahead to 2026, exploring upcoming myeloma treatments, major research advances, and the topics patients and carers most want to understand.
📌Key Takeaways:
Powerful new immunotherapy combinations could dramatically change how long treatments work.
CAR T-cell therapy and bispecific antibodies are moving closer to earlier use in myeloma care.
Living well with myeloma matt
027 From Functional Cure to Satsuma sized devices : Myeloma Highlights of the Year (Part 2 of 2)
Dr Jam Katari and Dr Sally Moore are joined by leading myeloma experts to look back on 2025’s biggest breakthroughs; from functional cures and new treatments to patient-friendly innovations.
This is part 2 of a seasonal special, featuring Professor Karthik Ramasamy and Dr. Ceri Bygrave. To hear the first part, please follow this link: Part1
🌟 Three key take-away points from Part 2
Funct
026 From Smouldering to Sci-Fi : Myeloma Highlights of the Year (Part 1 of 2)
Dr Jam Katari and Dr Sally Moore are joined by leading myeloma experts to look back on 2025’s biggest breakthroughs; from early treatment for smouldering myeloma to cutting-edge CAR-T therapy made inside the body.
This is part 1 of a seasonal special, featuring Professor Karthik Ramasamy and Dr. Ceri Bygrave. Please ensure you listen to our second part next week.
🌟 Three key take-away poi
025 An Additional New Hope - Understanding GPRC5D Treatment
This episode introduces Talquetamab - a newly approved bispecific antibody for relapsed myeloma - explaining how it works, who it’s for, and what side effects patients should expect and prepare for.
📌Key Takeaways:
Talquetamab is a brand-new treatment targeting GPRC5D - offering another effective option after several previous therapies.
Early side effects like fever, blood pressure chang
024 From Braces to Bone Regrowth: Modern Spine Care in Myeloma
Sean Molloy, renown spinal surgeon at the Royal National Orthopaedic Hospital (RNOH) NHS Trust in Stanmore explains how tailored bracing, breakthrough bone healing in myeloma, physiotherapy and minimally invasive vertebroplasty can transform pain, mobility and long-term spinal stability.
📌Key Takeaways:
A brace can act like “nature’s own surgery”, guiding powerful myeloma-driven bone r
023 Numbness, Tingling and Treatment: Making Sense of Neuropathy
Dr Jam & Sally unpack what neuropathy is, why it happens in myeloma treatment, and how patients can recognise, prevent and manage it to protect their quality of life.
📌Key Takeaways:
Know the signs early – tingling, numbness or pain shouldn’t be ignored; speak up before symptoms worsen.
Treatment can be adjusted – modern dosing and combinations make neuropathy less common and more ma
022 Remission, Relapse and Reality Understanding the R-Words in Myeloma
Dr Jam & Sally unpack what remission, relapse and refractory disease truly mean for people living with myeloma — and explore how close we are to talking about cure.
📌Key Takeaways:
Remission ≠ cure – myeloma can be controlled for years, even if it never fully disappears.
Monitoring matters – blood tests, bone marrow checks and scans together tell the full story.
Hope is growing – d
021 Understanding Risk in Myeloma: What Your Genetics Can Tell You
This episode unpacks the complex world of myeloma genetics - what high and standard risk really mean, how these tests guide treatment, and how future advances could lead to truly personalised care with Sarah Gooding.
Sarah is a colleague, and an Honorary Consultant Haematologist, based in Oxford.
📌Key Takeaways:
Your myeloma is unique - genetic tests help doctors understand how it may
020 Myeloma UK at the Heart: Advocacy, Research and Hope
This episode features Dr Sophie Castell, CEO of Myeloma UK, sharing insights into the charity’s vital work in research, advocacy, patient support, and tackling inequalities in myeloma care.
📌Key Takeaways:
Survival rates for myeloma have quadrupled — and living well is now as important as living longer.
Myeloma UK drives progress from early diagnosis to survivorship, always keeping
019 Four Drugs, One Goal - A New Option for Older Myeloma Patients
Welcome to The Myeloma Minutes. We've now moved to a fortnightly release schedule, so you can now hear us every-other Thursday.
This episode explains the newly approved four-drug treatment (Isatuximab, Velcade, Lenalidomide and Dexamethasone) for older people with myeloma who are not eligible for a stem cell transplant.
📌Key Takeaways:
This four-drug ‘quadruplet’ can keep myeloma under
018 BCMA Bispecific antibodies - Novel immunotherapies for relapsed myeloma
Welcome to The Myeloma Minutes. We've now moved to a fortnightly release schedule, so you can now hear us every-other Thursday.
This episode explores bispecific antibodies — how they work, the benefits they bring, and the key side effects patients and carers need to know about.
📌Key Takeaways:
Bispecific antibodies ‘wake up’ your immune system to fight myeloma — and response rates are h
017 The Myeloma Transplant Journey: A Nurse’s Guide to What Really Happens
Welcome to The Myeloma Minutes. We've now moved to a fortnightly release schedule, so you can now hear us every-other Thursday.
Specialist nurse Alex Scott walks patients and carers through every step of the autologous stem cell transplant process, from preparation to recovery, with clarity, compassion, and practical advice.
📌Key Takeaways:
It’s not just medical – emotional and practica
016 Life After Transplant: Maintenance Treatment in Myeloma Care
Welcome to The Myeloma Minutes. We've now moved to a fortnightly release schedule, so you can now hear us every-other Thursday.
This episode explores what happens after a stem cell transplant in multiple myeloma, focusing on consolidation and maintenance treatments - especially the use of lenalidomide - and how these therapies aim to sustain remission and quality of life.
📌Key Takeaways:
015 Inside the Transplant: What to Expect from an Autologous Stem Cell Transplant
Welcome to The Myeloma Minutes. We've now moved to a fortnightly release schedule, so you can now hear us every-other Thursday.
This episode walks you through every stage of an autologous stem cell transplant for myeloma - from preparation and chemotherapy to recovery and going home.
📌Key Takeaways:
You’ll get high-dose chemotherapy (melphalan) followed by your own stem cells - not some
014 Stem cells : what they are, mobilisation and collection.
Welcome to The Myeloma Minutes. We've now moved to a fortnightly release schedule, so you can now hear us every-other Thursday.
During this episode, Jam & Sally give an in-depth, patient-friendly guide to stem cell mobilisation - the essential step before undergoing an autologous stem cell transplant for multiple myeloma.
📌Key Takeaways:
Stem cells are collected from your blood -
013 Trojan Horse Therapy for Myeloma: A First for the NHS
Welcome to The Myeloma Minutes.
During this episode, Jam & Sally talk about a ground-breaking new combination therapy for multiple myeloma available on the NHS from this week. They highlight how it works, who it’s for, and what patients need to know.
📌Key Takeaways:
A new 'Trojan horse' drug is now approved on the NHS for first relapse myeloma.
Treatment is effective, flexible
012 Treatment Without Transplant: What Older Myeloma Patients Need to Know
Welcome to The Myeloma Minutes.
This episode explores the standard treatment for older or transplant-ineligible patients with myeloma, focusing on the DRD regimen, its side effects, and supportive care options.
📌Key points:
The DRD combo (Daratumumab, Lenalidomide, Dexamethasone) can keep myeloma controlled for years—even in older patients.
Steroids are powerful but often reduced o
011 Understanding Induction Therapy for Myeloma
Welcome to The Myeloma Minutes.
This episode guides you as a patient or carer through induction therapy for myeloma, focusing on the DVTD regimen, its side effects, supportive treatments, and how to manage them.
💡You'll learn:
How four powerful drugs work together to fight myeloma — and why you don’t need to suffer through side effects.
That neuropathy is reasonably common, but cat
010 The First Steps in Myeloma Care: What to Expect and Why It Matters
Welcome to The Myeloma Minutes.
During this episode, Drs Jam and Sally provide a clear and compassionate guide to first-line treatment for multiple myeloma.
💡You'll learn:
About 'induction', 'consolidation' and 'maintenance'—and why they matter.
Why pathways can often be dictated by age/health.
...And that the aim isn’t just survival—it’s living well with myeloma.
This podcast i
009 Bone Disease, Bisphosphonates & Myeloma: What You Need to Know
Welcome to The Myeloma Minutes.
This episode explores how bone disease affects people with multiple myeloma and how bisphosphonates like zolendronic acid can help manage pain, prevent fractures, and support treatment.
📌 Three Big Takeaways
Bone disease isn’t inevitable in myeloma—but needs fast action when it strikes!
Zolendronic acid can protect your bones and support myeloma trea
008 Scans and Myeloma : What you need to know, with Dr Shaheel Bhuva
Welcome to The Myeloma Minutes.
Dr Shaheel Bhuva, a radiologist (and long term colleague of Jam) joins Drs Jam and Sally to demystify scans in myeloma—explaining what they show, when they're used, and he'll dispel some myths around harmful amounts of radiation!
3 Key Teakaways:
Not all bone damage shows up on X-rays—some scans reveal disease before symptoms begin.
MRI and PET-CT sc
007 Smouldering Myeloma : Risks and monitoring - A Patient's guide
Welcome to The Myeloma Minutes.
During this episode Jam and Sally deep dive into Smouldering Myeloma—explaining what it is, how it’s monitored, the emotional toll of uncertainty, and what patients and carers can expect from evolving research and care approaches. Conversation points include:
Smouldering myeloma is a precancerous condition and it needs careful monitoring to catch chan
006 Steroids for Myeloma : Katy's Patient Story of Strength and Side Effects
Welcome to The Myeloma Minutes.
During this chat with Jam and Sally you'll hear a candid patient perspective on coping with a myeloma diagnosis and the emotional, physical, and practical realities of steroid treatment.
Hit ▶️ and you will learn:
That “Dexy's Midnight Runners” isn't just a band—it's a nickname for the steroids that turned myeloma treatment into a rollercoaster.
About
005 Taking Part in Research: Clinical Trials for Myeloma Explained
Welcome to The Myeloma Minutes.
In this episode Jam & Sally explore the role, process, benefits, and realities of clinical trials in myeloma care—what they are, how they work, and what patients and carers need to know.
Clinical trials offer access to cutting-edge treatments not yet widely available.
Taking part is always your choice—fully informed, and never pressured.
You’re
004 Steroids for Myeloma : The good, the bad and the ugly
Welcome to The Myeloma Minutes.
In this episode Jam & Sally explore the role of steroids in myeloma.
A cornerstone of myeloma therapy for decades, these powerful drugs have impacted every patient treated for myeloma.
They talk about their benefits, common side effects, and whether newer treatments could reduce the need for them in the future.
You'll hear about the following:
The im
003 Meet Your Myeloma Team: Who’s Who and How They Help
Welcome to The Myeloma Minutes. This is a living library of credible information for patients of multiple myeloma and their caregivers.
During this episode, Drs Jam and Sally talk about the roles of different healthcare professionals involved in a multiple myeloma care team within the NHS, helping patients and carers understand who does what and when.
As patients, we hear of Multidiscipl
002 What is Myeloma? : Patient questions answered
Welcome to The Myeloma Minutes. This is a living library of credible information for patients of multiple myeloma and their caregivers.
Doctors Jam and Sally treat and speak with patients and caregivers daily. During this episode they talk about the most common and biggest questions they are asked, including:
What is Myeloma? Is Multiple Myeloma different?
Where does this type of can
001 The Myeloma Minutes : An introduction
Dr. Sally Moore
Dr Sally Moore is a Bristol based consultant who specialises in treating patients living with multiple myeloma and other plasma cell disorders. She oversees the delivery of clinical research studies for myeloma patients and has academic interests in how to maximise quality of life for patients and improve outcomes in older, less fit patients. She frequently contributes to
Recommended
The Healer Revolution
Becoming: HER with Nikki Spoelstra
Booked, Blonde & Busy w/ Olivia Ponton
McKinsey on Consumer and Retail
megahired.com
Hard Knocks Podcast
Effective Weight Loss for Moms | High protein, Strength Training, Lose Weight, Meal Planning, Fat Loss, Healthy Habits
The Human-Animal Connection - Pet Life Radio Original
The Daily
World News Tonight with David Muir
The Joe Rogan Experience
English Vocabulary Help
