Metabolic Mind explores the connection between metabolism and brain health, focusing on how metabolic interventions like ketogenic therapy can treat serious mental illnesses such as Bipolar Disorder, Schizophrenia, and Major Depressive Disorder. The podcast discusses topics in metabolic psychiatry to help listeners understand how these approaches might benefit themselves or loved ones. It also directs viewers to their YouTube channel for additional content.
Episodes

What Every Caregiver of Adult Children Should Know About Mental Health
When someone you love is experiencing serious mental illness, caregiving can become a long process of learning when to step in and when to step back, while continuing to show up through uncertainty.For Family Caregivers Month, Dr. Bret Scher speaks with Janet Ebos and her son Seth about the years they spent navigating depression, mania, psychosis, recovery, and the changing relationship between a

How Personal Recovery Can Spark a Movement for Better Health
For some, experiencing meaningful change through metabolic therapies sparks a new purpose: helping others find hope and new options.In this special Metabolic Mind video, Hannah Warren interviews two advocates whose experiences show how personal recovery stories and grassroots organizing are expanding the conversation around chronic disease and mental health.Eric Rodgers shares how ketogenic and ot

BITESIZE: How Sleep Affects Brain Metabolism and Alzheimer’s Risk
Stress can disrupt sleep quickly, and when poor sleep becomes a pattern, the effects can reach far beyond next-day fatigue.For International Stress Awareness Week, we’re calling attention to the broader health effects of chronic stress, including the way disrupted sleep can affect cortisol, metabolism, and brain function.In this video, Dr. Scher discusses the glymphatic system’s proposed role in c

Dr. David Unwin on Type 2 Diabetes Remission With Low-Carb Nutrition
Type 2 diabetes is often treated as a chronic, progressive disease, but Dr. David Unwin has spent years showing that, for many patients, remission is possible through low-carb nutrition and a different approach to care.In this episode, Dr. Bret Scher speaks with Dr. Unwin about how his work as an NHS primary care physician changed after he began focusing on insulin resistance, carbohydrate intake,

Q&A: Dr. Ede on Sweetener Studies, Oxalate Dumping, Exercise & Bone Health
Can stevia fit into a ketogenic diet? What does the evidence say about oxalates? And how might a ketogenic diet affect bone health?In this episode of Metabolic Mailbag, Dr. Bret Scher and psychiatrist Dr. Georgia Ede answer listener questions about sweeteners, exercise, ketone levels, continuous ketone monitoring, and more.They discuss:Why stevia can still be considered a keto-friendly sweetener,

Introducing MetPsy: A Global Community for Metabolic Psychiatry
Metabolic psychiatry is growing quickly, and clinicians and researchers around the world have been asking for a better way to connect and learn from one another to help move the field forward.Dr. Bret Scher speaks with Dr. Kirk Nylen, Managing Director of Neuroscience at Baszucki Group, and psychiatrist Dr. Georgia Ede about MetPsy, a new global community for clinicians and researchers working in

Dr. Satchin Panda on How Your Body Clock Shapes Metabolic Health
Meal timing, morning light, sleep, and exercise can all influence circadian rhythm, with potentially important effects on metabolic health.In this episode, Dr. Bret Scher speaks with circadian biology expert Dr. Satchin Panda about how our internal clocks work, what disrupts them, and how everyday timing choices can affect metabolism, brain function, and long-term health.Dr. Panda describes how li

BITESIZE: Dr. Deanna Kelly on Clozapine and Ketogenic Therapy
Can ketogenic therapy help offset some of the metabolic side effects of clozapine while preserving its psychiatric benefits?Dr. Deanna Kelly, a leading clozapine researcher, joins Dr. Bret Scher to discuss what she has seen clinically when ketogenic therapy is used alongside clozapine and other antipsychotic medications.Dr. Kelly shares the case of a patient taking clozapine who also had diabetes

BITESIZE: ADHD and Dementia: Is Brain Metabolism the Link?
A recent study published in JAMA Psychiatry found that adults with ADHD had more than a fourfold higher association with cognitive impairment and dementia later in life. The finding doesn't mean ADHD causes dementia, but it raises important questions about what these conditions may share biologically.In this video, Dr. Bret Scher breaks down the study and explores one possible connection: brain en

Dr. Georgia Ede on ADHD, Brain Metabolism, and Ketogenic Therapy
ADHD is often described as a problem with attention or hyperactivity, but psychiatrist Dr. Georgia Ede argues that the condition is much more complex, involving executive function, dopamine regulation, and potentially brain energy metabolism.In this episode of Metabolic Mind, Dr. Bret Scher and Dr. Georgia Ede take a deeper look at ADHD, from how it is diagnosed and treated to emerging research on

Q&A: Carnivore Protein Levels, Key Nutrients, and Keto After Menopause
Does perimenopause make ketosis harder? Can a carnivore diet provide too much protein? And which nutrient deficiencies matter most for mental health?In this episode of Metabolic Mailbag, Dr. Bret Scher and psychiatrist Dr. Georgia Ede answer listener questions about ketogenic therapy, menopause, carnivore diets, protein intake, and nutrition for mental health.They discuss how hormonal changes duri

BITESIZE: What “Healthy” Food Labels May Be Hiding
Some “healthy” foods may be working against your metabolic health.In this episode of Metabolic Mind, Dr. Bret Scher examines how products such as agave nectar, commercial green juices, low-fat fruit yogurt, and açaí bowls can create a health halo while delivering large amounts of rapidly digestible sugar.Dr. Scher explains how liquid carbohydrates, added sugars, and concentrated fructose may affec

Dr. Bill Schindler on Ancestral Diets and Modern Nutrition
How did humans go from being deeply connected to our food to barely knowing where it comes from or how it was made?In this episode of Metabolic Mind, Dr. Bret Scher speaks with experimental archaeologist and chef Dr. Bill Schindler about what human evolution can teach us about food, nutrition, and the way we eat today. Drawing on archaeology and his time with hunter-gatherer communities around the

BITESIZE: Ketogenic Diet Dangerous? Breaking Down the New Study
A new study claims ketogenic diets cause liver damage and early death. Here’s what you need to know.A 2025 mouse study recently made headlines, warning that ketogenic diets may lead to fatty liver, high triglycerides, and a shortened lifespan.But here’s the catch:These findings were in genetically altered mice fed a 90% fat diet, filled with highly synthetic components, and they contradict what h

Q&A: Food Noise, Aging on Low-Carb, Carnivore Microbiome & Keto Snacks
Can ketosis change symptoms of bulimia? Is low-carb eating safe in your 80s? And what really happens to digestion on a carnivore diet?In this episode of Metabolic Mailbag, Dr. Bret Scher answers questions about ketogenic therapy for eating disorders, low-carb diets in older adults, carnivore diets and gut health, constipation on a ketogenic diet, and even a few easy keto movie-night snacks. He als

Dementia Prevention Through a Metabolic Lens
Alzheimer’s disease is usually discussed in terms of plaques, tangles, and genetics. Dr. Stephen Cunnane has spent years studying another piece of the puzzle: what happens when the aging brain can no longer use glucose efficiently, and whether ketones can help fill that energy gap.In this interview, Dr. Bret Scher and Dr. Cunnane discuss the metabolic side of cognitive decline, including insulin r

BITESIZE: Dr. Georgia Ede’s Guide to Better Mental Health in College
College can be one of the most exciting times of your life, but it can also put enormous pressure on a brain that's still developing.Psychiatrist Dr. Georgia Ede spent 12 years working as an on-campus psychiatrist at Harvard University and Smith College. In this video, she explains why college can be such a vulnerable time for mental health and how sleep, nutrition, alcohol, smoking, vaping, and o

BITESIZE: Keto Outperformed Mediterranean and Low-Fat Diets in New RCT for Fatty Liver and Prediabetes
Does reducing carbohydrates improve metabolic health beyond what can be explained by weight loss alone?Dr. Bret Scher breaks down a new randomized controlled trial published in Cell Metabolism that compared three diets in people with prediabetes and fatty liver disease: a ketogenic diet, a higher-carbohydrate Mediterranean diet, and a very low-fat, plant-forward diet.One challenge with ketogenic d

Cynthia Thurlow: Nutrition, Fasting, and Exercise for Perimenopause
For many women, the wellness strategies that carried them through their 20s and 30s can start to backfire in perimenopause. Changes in hormones, muscle mass, insulin sensitivity, sleep, and stress can make midlife feel like a completely different metabolic landscape.In this episode of Metabolic Mind, Dr. Bret Scher speaks with nurse practitioner Cynthia Thurlow about why perimenopause can act like

How to Build a Vegetarian Ketogenic Diet for Mental Health
Hannah Warren spent years living with severe bipolar I disorder before discovering metabolic therapies in 2021. Today, Hannah has been in remission for more than five years, is no longer taking psychiatric medication, and works as Metabolic Mind’s Community Engagement & Advocacy Manager, helping others understand the emerging field of metabolic psychiatry.In this course module, created as part

How Experiential Training Builds Clinician Confidence in Ketogenic Therapy
How can clinicians become more comfortable using ketogenic therapy in mental health care? In this episode of Metabolic Mind, Dr. Bret Scher speaks with Dr. Deanna Kelly about Live It, Launch It!, a training program designed to help clinicians learn ketogenic therapy by experiencing it themselves.Dr. Kelly explains why evidence-based treatments can still take years to reach everyday clinical practi

LDL, ApoB & More: What Really Shapes Heart Disease Risk?
How should we think about LDL and ApoB, and how much metabolic health changes the cardiovascular risk picture?In this episode of Metabolic Mind, Dr. Bret Scher speaks with vascular surgeon Dr. Lily Johnston about cholesterol and plaque formation, along with the need to personalize cardiovascular prevention.👉 Download our Make Sense of Your Cholesterol guide: https://metmind.co/cholesterol-listener

BITESIZE: Is RFK Right About Saturated Fat? Here's the Truth
Is saturated fat really the villain it’s been made out to be? Or has decades of poor research and dietary policy misled us?In this video, Dr. Bret Scher dives into the controversy surrounding RFK Jr.'s call to remove the cap on saturated fat, and the Wall Street Journal’s misleading take on it.We explore:✅ Why saturated fat doesn’t just mean pizza and ice cream✅ The science behind whole foods vs.

BITESIZE: Two LDL Trials. Two Different Results.
Should LDL be treated? In this episode of Metabolic Mind, Dr. Bret Scher explains why the better question is who may benefit from LDL lowering, how aggressively it should be treated, and what outcomes matter most to the individual patient.👉 Get our free 11-page Cholesterol Guide to better understand your lipid panel and prepare for a conversation with your clinician: https://metmind.co/cholesterol

Vegan Keto and Bipolar Disorder: Dyane Harwood’s Story
Is it possible to follow a diet that’s both vegan and keto? And can a diet like that be used as part of a care plan for bipolar disorder? In this episode of Metabolic Mind, Dr. Bret Scher speaks with author and advocate Dyane Harwood about how she uses a vegan ketogenic diet as part of her treatment for postpartum bipolar disorder.Dyane shares how she first discovered vegan keto, why she started t

Q&A: Why Protein Shakes Leave You Hungry, Fasting, Basal Metabolic Rate & More
Can therapeutic ketosis be considered for type 1 diabetes and bipolar disorder? In this Metabolic Mailbag episode, Dr. Bret Scher and producer Erica Gerard answer viewer questions about ketogenic therapy, type 1 diabetes, Parkinson’s medications, omega-3s, fasting, protein intake, metabolic rate, and why some protein foods are more filling than others.They cover:The association between type 1 diab

BITESIZE: Cholesterol Results Explained: Beyond the LDL Number
A red flag next to your LDL number can feel alarming, but LDL is only one part of a much larger cardiovascular risk picture. In this episode of Metabolic Mind, cardiologist and lipidologist Dr. Bret Scher explains how to read a cholesterol panel with more context and less fear.Dr. Scher walks through LDL, triglycerides, HDL, non-HDL cholesterol, ApoB, Lp(a), and the triglyceride-to-HDL ratio. He a

Carnivore vs. Vegan Keto: Can Both Work?
Can carnivore and vegan diets both be used as ketogenic therapies?In this episode of Metabolic Mind, Dr. Bret Scher speaks with registered dietitian Denise Potter about two widely debated approaches to nutrition. They explore how each can be evaluated when someone is considering a ketogenic diet to support psychiatric, neurological, or metabolic health.Denise brings more than 30 years of clinical

Dr. Peter Ballerstedt on Animal Foods & Malnutrition
Animal-sourced foods are often framed as a problem for human health and environmental sustainability. In this episode of Metabolic Mind, Dr. Bret Scher speaks with forage agronomist and ruminant nutritionist Peter Ballerstedt, PhD (@GrassBased) about livestock, malnutrition, chronic disease, and why restoring metabolic health may require a broader conversation about nutrition and sustainability.Pe

BITESIZE: Low-Carb vs. Keto: Why the Difference Matters
The terms “low-carb” and “ketogenic” are often used interchangeably, but are they the same thing?Not quite.A low-carb diet can be a powerful tool for improving blood sugar, triglycerides, insulin levels, inflammation, and overall metabolic health. Ketogenic diets, on the other hand, involve a deeper level of carbohydrate reduction that shifts the body into nutritional ketosis, where ketones become

Making Keto Work on a College Campus
Starting college can change almost everything about your routine, including how, when, and what you eat. For students using ketogenic therapy as part of their mental health treatment, that transition can take some planning.In this interview, Dr. Bret Scher speaks with licensed mental health counselor Nicole Laurent about how students using ketogenic therapy with clinical support can navigate a col

BITESIZE: Dr. Explains: It’s Not the Fat, It’s Not the Processing, It’s THIS
Every day, we make choices about what to eat. But how often do we realize how deeply these choices affect both our physical and mental health?Today, an estimated 93% of adults in America are showing signs of poor metabolic health, which is a major contributor to many chronic conditions like heart disease, type 2 diabetes, obesity, and many psychiatric disorders.The good news is that more people ar

Do We Really Eat Too Much Protein?
Do most people really need to eat less protein to live longer? In this episode of Metabolic Mind, Dr. Bret Scher responds to a new review getting attention for the claim that protein restriction may extend lifespan, and explains why that message can be misleading for older adults, active people, and anyone focused on metabolic health.Dr. Scher walks through the biology behind the headlines, includ

Q&A: Keto Safety After a Stent, During Pregnancy, and in Serious Mental Illness
Can ketogenic therapy be safe for someone with heart disease, atherosclerosis, or a stent? Can you follow a ketogenic diet without losing weight? In this Metabolic Mailbag episode, Dr. Bret Scher answers viewer questions about ketogenic therapy, cardiovascular risk, anorexia recovery, pregnancy and nursing, schizophrenia remission, keto on a budget, and whether doctors learn about ketogenic therap

Obesity Medicine Doctor on Metabolic Health and Ketosis
How can clinicians use real-world patient data to personalize metabolic health care? In this episode of Metabolic Mind, Dr. Bret Scher speaks with Dr. Jeff Pua, an internal medicine and obesity medicine physician, about obesity medicine, metabolic syndrome, nutritional ketosis, and what clinicians can learn from patient outcomes in everyday practice.Dr. Pua shares how his approach has evolved from

BITESIZE: How Chronic Stress Disrupts Metabolic Health
Can chronic stress undermine metabolic health, even when nutrition, sleep, and exercise are in place?In this episode of Metabolic Mind, Dr. Bret Scher explains why stress recovery is an important part of metabolic health and how chronic cortisol and adrenaline activation may affect insulin resistance, blood pressure, inflammation, sleep, and long-term cardiometabolic health.Dr. Scher breaks down t

Could GLP-1s Help Treat Bulimia and Binge Eating?
Could GLP-1 medications play a role in treating bulimia or binge eating disorder? In this episode of Metabolic Mind, Dr. Bret Scher speaks with Paige Gordon and psychiatrist Dr. Michael Lutter about Paige’s personal experience using a GLP-1 medication for treatment-resistant bulimia, and why researchers are beginning to explore the neurobiology of binge eating.Paige shares how years of therapy and

First Keto RCT for Serious Mental Illness: Hear from the Study Authors
Can ketogenic therapy improve symptoms, cognition, and metabolic health in people living with serious mental illness?In this episode of Metabolic Mind, Dr. Bret Scher speaks with Dr. Judy Ford, Juliette Kyner (previously Juliette Ward), and Dr. Shebani Sethi about the first-ever randomized controlled trial of a ketogenic diet intervention in individuals living with schizophrenia spectrum disorder

BITESIZE: New GLP-1 Study Raises Metabolic Health Questions
Do GLP-1 medications improve metabolic health as much as they support weight loss? A new observational study in the Annals of Internal Medicine raises an important question about semaglutide, insulin discontinuation, type 2 diabetes, and what meaningful metabolic improvement may require.In this episode of Metabolic Mind, Dr. Bret Scher breaks down a real-world study of more than 9,000 veterans wit

Q&A: Insulin Resistance, Reaching Ketosis, Bone Density, and Rating Popular Keto Products
The questions around ketogenic therapy keep getting more layered, and your latest submissions reflect that. In this Metabolic Mailbag episode, Dr. Bret Scher and producer Erica Gerard tackle some of the most common questions about insulin resistance, ketosis, bone health, and a fun rapid-fire round on popular ketogenic products and practices.In this discussion, you'll learn:The difference between

Robyn Dobbins Reflects on Her Story in The Cholesterol Code
What does it look like to put bipolar II disorder into remission and become a voice of hope for others living with serious mental illness? Robyn Dobbins joins Hannah Warren from Metabolic Mind to reflect on how ketogenic therapy transformed her life, and what it was like to see her own story featured in The Cholesterol Code documentary.In this conversation, you'll learn:What it was like for Robyn

BITESIZE: Keto 101: Everything You Need to Know About Ketone Testing
How do you know if you're actually in ketosis? Should you test ketones? And if so, what's the best method: blood, breath, or urine?Dr. Bret Scher breaks down everything you need to know about ketone testing, including when testing matters, which tools are most accurate, and how to interpret your results based on your goals. Whether you're using a ketogenic diet for metabolic health, weight loss, o

Targeting Cancer Metabolism With Ketogenic Therapy and Fasting
Could metabolic therapies become part of the future of cancer care?That question sits at the center of Dr. Bret Scher’s conversation with neurologist and researcher Dr. Matthew Phillips, whose recent study explored a metabolic approach in people with glioblastoma, one of the most aggressive forms of brain cancer.Rather than relying on a single intervention, the study combined a ketogenic diet, int

BITESIZE: JAMA Psychiatry Analysis: What 50 Studies Tell Us About Nutrition For Depression & Anxiety
Can a ketogenic diet help improve mood and reduce depressive symptoms?A new meta-analysis published in JAMA Psychiatry examined 50 different keto studies, totaling over 40,000 participants, that included depression and anxiety outcomes. The results of the review demonstrated a modest improvement in depression symptoms across different populations and diagnoses in both controlled and real-world sce

BITESIZE: New Study: Could GLP-1 Medications Be Reducing Physical Activity?
Do GLP-1 medications like Ozempic reduce physical activity? Preliminary research suggests they might, raising important questions about how exercise should be supported alongside treatment.GLP-1 medications are helping many people achieve meaningful weight loss and metabolic improvements. At the same time, findings presented at the Endocrine Society’s annual meeting showed declines in daily steps

GLP-1s + Ketogenic Diet: The Future of Weight Loss?
Could a ketogenic diet and low-dose GLP-1 medications work better together? A new case series suggests they might, while highlighting a more personalized approach to metabolic health.GLP-1 medications have transformed obesity treatment, but they aren't the only tool available. In this interview, Dr. Bret Scher speaks with physician assistant Bill Jensen about a newly published case series explorin

Dr. Ford Brewer on the Future of Heart Health & The Cholesterol Code
What does it take to truly understand and assess cardiovascular risk in modern medicine?Dr. Bret Scher joins Dr. Ford Brewer at the Collaborative Science (CoSci) conference to discuss the recent screening of The Cholesterol Code documentary and the bigger picture of metabolic health, cardiac imaging, and the future of risk assessment.In this conversation, you'll learn:Dr. Ford Brewer's reaction to

BITESIZE: We Can Reverse T2 Diabetes. That Doesn’t Mean Patients Are at Fault
Type 2 diabetes is a chronic disease that can often be put into remission. So why do so many people still struggle to get better?In this discussion, Dr. Bret Scher explores how the environments we create, from our food system to our healthcare system, shape metabolic health in ways that are often overlooked.Using a thought experiment as a starting point, he examines why remission is possible for m

Meet Dr. Bret Scher: The Host Behind Metabolic Mind
Dr. Bret Scher began his career practicing conventional cardiology, following the same guidelines taught in medical training. Today, he is Medical Director at Metabolic Mind, as well as The Coalition for Metabolic Health, and one of the leading voices advancing metabolic health, ketogenic therapy, and metabolic psychiatry.What changed?In this special episode, Metabolic Mind producer Erica Gerard t

Psychiatry Research Priorities: Keto, GLP-1s, Exercise & Mental Illness
What questions matter most to people living with serious mental illness when it comes to metabolic interventions?Dr. Dina Farran and Dr. Toby Pillinger from King's College London set out to answer exactly that through a Priority Setting Partnership, an extensive collaborative process bringing together people with lived experience, family members, caregivers, clinicians, and researchers to identify

BITESIZE: Lipidologist Questions the New Keto and Liver Disease Study
A recent study made headlines for claiming a ketogenic diet may worsen fatty liver disease and raise triglycerides. But when you take a closer look at the research, it’s clear that the conclusions are far less supported than the coverage suggests.To clear things up, Dr. Bret Scher breaks down what the study actually found, where the methodology falls short, and what the broader body of research ha

How One CGM Changed This Cardiologist’s Life
Is a plant-based diet the best for supporting metabolic health? Cardiologist Dr. Jaimela Dulaney spent years practicing plant-based nutrition before her own experience with insulin resistance, blood sugar swings, and endurance running led her to rethink what personalized nutrition can look like.In this episode, Dr. Bret Scher speaks with Dr. Dulaney about what changed her perspective, both persona

Dr. Dom D'Agostino on Why Metabolic Health Matters for the Brain
Metabolic health may be the foundation of a healthy brain, and a growing community of researchers, clinicians, and educators is working to bring that message into mainstream medicine.In this interview, Dr. Bret Scher talks with Dr. Dom D'Agostino at the Citizen Science Initiative (CoSci) conference to discuss everything from the recent screening of The Cholesterol Code documentary to the rise of N

First RCT of Keto for Schizophrenia & Bipolar Disorder: Results & Future Directions
New results from first-of-its-kind randomized controlled trial on a ketogenic diet for schizophrenia and bipolar disorder with psychosis offer important insights into metabolic psychiatry and mental health treatment.In this interview, Dr. Bret Scher sits down with Dr. Julie Milder to walk through the study results, recently published in Schizophrenia Bulletin. As the first RCT in psychosis-spectru

BITESIZE: Results from first RCT of Keto for Schizophrenia + Bipolar: Metabolic Wins & Mental Health Signals
New evidence from the first-ever RCT shows ketogenic therapy can rapidly improve metabolic health in schizophrenia-spectrum and bipolar I disorders, and shows early signals of psychiatric improvement.In this video, Dr. Bret Scher breaks down this newly published study led by Dr. Judith Ford at UCSF: the first randomized controlled trial with peer-reviewed results investigating ketogenic therapy in

Q&A: Are Seed Oils Dangerous? Anhedonia, Ketoacidosis, Ketone Levels & More
Why are seed oils suddenly everywhere in nutrition debates? What is anhedonia? Is the dawn phenomenon something to worry about? And how can you tell the difference between nutritional ketosis and ketoacidosis?In this Metabolic Mailbag episode, Dr. Bret Scher and producer Erica Gerard answer some of the most common questions from our community about ketogenic therapy, mental health, metabolism, and

BITESIZE: A Cardiologist Weighs In on the NATURE-CT Vs. Ketogenic Diet Debate
A newly published study called NATURE-CT is generating significant attention in the cardiovascular and ketogenic communities, but some of the conclusions being drawn online don't hold up to scientific scrutiny. Dr. Bret Scher walks through what the study actually shows, what it doesn't, and why comparisons being made to ketogenic therapy are scientifically misleading.In this discussion, you'll lea

BITESIZE: Keto 101: Beginner’s Guide to Meals, Snacks, and Carb Limits
What should you eat on keto? A ketogenic diet shifts your body from burning carbs to burning fat and ketones, and it can be a powerful tool for supporting metabolic health as well as mental health. But knowing what to eat, what to avoid, and how to get started makes all the difference.Here, Dr. Bret Scher walks you through the essentials:The best proteins, fats, and low-carb vegetables for ketoFoo

David Baszucki: What My Son's Recovery Taught Me About Mental Illness
David Baszucki - founder and CEO of Roblox - sits down with his son Matthew for the first time on a podcast together. They walk through Matthew's five-year journey with severe, treatment-resistant bipolar I disorder: the first manic episode in 2016, multiple hospitalisations, the dozens of medications, the 2017 incident in Los Angeles when David flew down on a rescue mission to find Matt homeless

Dr. Eric Westman on the Future of Metabolic Medicine
The Cholesterol Code documentary is challenging long-held assumptions about LDL cholesterol, ketogenic diets, and what really matters for cardiovascular risk.In this interview, Dr. Bret Scher sits down with Dr. Eric Westman, internist and low-carb researcher, to discuss the film's impact and what it could mean for the future of clinical practice.From Dave Feldman's citizen science journey to the g

Q&A: Does Keto Help or Hurt AFib? KETO-CTA Study, Ketone levels & More
Can ketogenic therapy help atrial fibrillation? What should you make of the KETO-CTA study? And do higher ketones always mean better results?In this Metabolic Mailbag episode, Dr. Bret Scher answers audience questions about cardiovascular health, ketosis, ketone levels, and how to personalize a ketogenic approach based on your goals and metabolic health. From AFib concerns to cholesterol controver

BITESIZE: Do Eggs Actually Cause Heart Disease?
Are eggs bad for you because they may raise cholesterol?It's one of the most common nutrition questions in cardiology, and one of the most misunderstood. The reality is that raising cholesterol and harming your health aren't always the same thing, and when it comes to eggs, the data tells a much more nuanced and reassuring story than most people have been led to believe.In this conversation, Dr. B

Dr. Ken Berry on the Medical Landscape of Chronic Disease
Can ketogenic therapy challenge mainstream thinking on cholesterol, diabetes, and evidence-based medicine? At the CoSci conference, Dr. Ken Berry shares his reaction to The Cholesterol Code documentary and explains why more clinicians are questioning long-standing assumptions about metabolic health, LDL cholesterol, and the treatment of chronic disease.In this conversation, Dr. Berry discusses the

BITESIZE: The New Protein Guidelines Reignited the Plant vs. Animal Debate
Protein recommendations have changed and not everyone is happy about it. Here's what the new federal protein guidelines actually mean for your health, and why the pushback is missing the point.A recent PBS article argued that doubling the current protein guidelines would push people toward junk food and processed products. But as a cardiologist, Dr. Bret Scher explains why that concern, while unde

BITESIZE: Omega-3 Supplements and Cognitive Decline? Here’s the Full Story
A new Alzheimer’s study linked omega-3 fish oil (EPA & DHA) supplement use to faster cognitive decline, but the real story is far more nuanced than the headlines suggest.In this discussion, cardiologist Dr. Bret Scher breaks down the study and explains why the quality, freshness, and source of omega-3s may matter more than most people realize.The study used data from the Alzheimer’s Disease Ne

Whole-Person Psychiatry Is Changing Mental Health Care—with Meru Health’s Kristian Ranta
After losing his brother to suicide despite being in psychiatric care, entrepreneur Kristian Ranta began asking difficult questions: Why do so many people struggle despite treatment? What if mental health care is overlooking key drivers of recovery?In this conversation, Dr. Bret Scher sits down with Kristian Ranta, founder of Meru Health, to explore a model that approaches mental health care diffe

New Study from 25-Year Eating Disorder Expert
Anorexia nervosa has one of the highest mortality rates of any psychiatric illness, yet effective biological treatments remain limited. For many people living with the condition, even after successful weight normalization, persistent psychological symptoms, including obsessive thoughts about food, shape, and weight, continue to drive relapse.In this conversation, Dr. Bret Scher sits down with Dr.

First Keto Trial for Anorexia Nervosa: 72% Showed Recovery
A new study demonstrates that ketogenic therapy could be an option for individuals living with weight-normalized anorexia nervosa.One of the primary goals of anorexia nervosa treatment is restoring weight, and while this is an important milestone, many individuals continue to experience psychological symptoms.Dr. Guido Frank, Professor of Psychiatry at UC San Diego, has spent more than 25 years re

BITESIZE: New Study: Why Did This Drug Lower Cholesterol But Not Heart Plaque?
Lower triglycerides, lower remnant cholesterol, lower ApoB. Zero change in coronary artery plaque. A new clinical trial is forcing a bigger conversation about how we treat cardiovascular disease.The drug was Olezarsen, an APOC3 inhibitor. The blood work looked impressive. The heart scans did not. So why would lowering well-established cardiovascular risk factors fail to move the needle on plaque?

Keto as an Adjunct to CBTp? Nicole Laurent Explains
Could ketogenic therapy help people with schizophrenia spectrum disorders engage more successfully with CBT? A new conceptual framework explores this powerful adjunctive approach.CBTp is considered a gold-standard treatment for schizophrenia spectrum disorders, but many patients struggle to initiate, participate in, and complete it. Cognitive deficits, sleep disturbances, low distress tolerance, a

Q&A: Keto for PCOS, Cravings, & Women’s Health with Temple Stewart
How many carbs should you eat on a ketogenic diet? Do ketone levels matter? And why do cravings hit so hard? Is Dairy recommended?In this Metabolic Mailbag episode, registered dietitian and medical student Temple Stewart breaks down some of the most common challenges people face when starting and maintaining a ketogenic diet, especially for PCOS (PMOS), metabolic health, and long-term sustainabili

GLP-1s, Weight Loss, and the Stigma We Don’t Talk About
A recent report highlighted a surprising trend: individuals using GLP-1 medications such as Ozempic and Wegovy may be facing even more social stigma than those who remain overweight. And while neither deserves any stigma at all, it raises an important question about how we judge health choices in modern medicine.In this conversation, Dr. Bret Scher reflects on whether his own critiques of GLP-1 me

APA Hallway Talk: Are Psych Meds Overprescribed?
Psychiatric medication tapering* is becoming one of the most important and controversial conversations in mental health care.In the wake of the American Psychiatric Association Annual Conference, Dr. Bret Scher explores the growing debate around psychiatric medication “deprescribing,” responsible tapering, overprescription, and the urgent need for better research and clinician guidance.This discus

Eggs and Alzheimer’s: New Study Challenges Assumptions
A new study suggests that eating more eggs may be linked to a lower risk of dementia. But what does the research actually show?Dr. Bret Scher breaks down the headlines, the limitations of observational nutrition research, and the surprisingly important detail hidden in the baseline data.The people eating the fewest eggs entered the study with what many would consider “healthier” lifestyles:👉 Lower

Reversing & Preventing Fatty Liver with Metabolic Therapies | Dr. Adam Wolfberg
Fatty liver disease (MASLD) is a major cause of liver disease and even liver failure. But many are surprised to learn it’s not primarily a liver problem. Growing evidence suggests the root issue may be metabolic dysfunction affecting the entire body, and that perspective can drastically change how we approach treating and preventing it.In this interview, Dr. Bret Scher sits down with Dr. Adam Wolf

Can Insulin Resistance Raise Suicide Risk?
Can insulin resistance increase the risk of suicide?In this video, Dr. Bret Scher breaks down a new study published in Translational Psychiatry that links metabolic dysfunction with higher rates of suicidal ideation, attempts, and death.Dr. Scher covers:How biomarkers like blood glucose, insulin, lipid profiles, and waist circumference relate to suicide riskHow this study fits with the growing evi

The Problem With One-Size-Fits-All Nutrition
For decades, nutrition advice has centered on a single idea: that there’s one “right” way to eat for everyone. The standard low-fat, Mediterranean-style diet approach has shaped how we think about health. But it’s missing a critical piece.Here, Dr. Bret Scher breaks down the limitations of universal dietary recommendations and why relying on observational nutrition research may not provide clear a

Q&A: Keto Sleep Issues, Carnitine Levels, Brain Insulin Resistance & More
Can ketosis trigger insomnia or even mania? Do you need supplements like L-carnitine to support ketone production? Is whey protein helping or hurting your metabolic health? And how do you maintain or gain weight on a ketogenic diet without losing ketosis?Harvard-trained psychiatrist Dr. Georgia Ede and cardiologist Dr. Bret Scher tackle your biggest questions in this Metabolic Mailbag episode, bre

ApoB Explained: What Your LDL Test Doesn’t Tell You
For decades, LDL cholesterol has been the go-to metric for assessing heart disease risk. But growing research suggests there's a better predictor: ApoB. But is it a predictor in itself, or is it a marker of something even more important?Apolipoprotein B (ApoB) is a protein found on all potentially harmful lipoprotein particles, like LDL, VLDL, and remnants. Because each particle carries one ApoB,

Keto 101: Everything You Need to Get Started
Starting a ketogenic diet, reaching ketosis, and setting the right keto macros can feel overwhelming at first, but the fundamentals are simpler than they seem. In this video, Dr. Bret Scher breaks down how to start a keto diet step by step, including how to lower carbs, balance protein, and use fat as your primary fuel source.Whether your goal is weight loss, metabolic health, or therapeutic ketos
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