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Metabolic Mind

Metabolic Mind

Bret Scher 213 Episodes Aug 23, 2026

Metabolic Mind explores the connection between metabolism and brain health, focusing on how metabolic interventions like ketogenic therapy can treat serious mental illnesses such as Bipolar Disorder, Schizophrenia, and Major Depressive Disorder. The podcast discusses topics in metabolic psychiatry to help listeners understand how these approaches might benefit themselves or loved ones. It also directs viewers to their YouTube channel for additional content.

Episodes

Obesity Medicine Doctor on Metabolic Health and Ketosis
Obesity Medicine Doctor on Metabolic Health and Ketosis Aug 23, 2026 14:16 How can clinicians use real-world patient data to personalize metabolic health care? In this episode of Metabolic Mind, Dr. Bret Scher speaks with Dr. Jeff Pua, an internal medicine and obesity medicine physician, about obesity medicine, metabolic syndrome, nutritional ketosis, and what clinicians can learn from patient outcomes in everyday practice.Dr. Pua shares how his approach has evolved from
BITESIZE: How Chronic Stress Disrupts Metabolic Health
BITESIZE: How Chronic Stress Disrupts Metabolic Health Aug 20, 2026 07:58 Can chronic stress undermine metabolic health, even when nutrition, sleep, and exercise are in place?In this episode of Metabolic Mind, Dr. Bret Scher explains why stress recovery is an important part of metabolic health and how chronic cortisol and adrenaline activation may affect insulin resistance, blood pressure, inflammation, sleep, and long-term cardiometabolic health.Dr. Scher breaks down t
Could GLP-1s Help Treat Bulimia and Binge Eating?
Could GLP-1s Help Treat Bulimia and Binge Eating? Aug 18, 2026 38:55 Could GLP-1 medications play a role in treating bulimia or binge eating disorder? In this episode of Metabolic Mind, Dr. Bret Scher speaks with Paige Gordon and psychiatrist Dr. Michael Lutter about Paige’s personal experience using a GLP-1 medication for treatment-resistant bulimia, and why researchers are beginning to explore the neurobiology of binge eating.Paige shares how years of therapy and
First Keto RCT for Serious Mental Illness: Hear from the Study Authors
First Keto RCT for Serious Mental Illness: Hear from the Study Authors Aug 16, 2026 28:24 Can ketogenic therapy improve symptoms, cognition, and metabolic health in people living with serious mental illness?In this episode of Metabolic Mind, Dr. Bret Scher speaks with Dr. Judy Ford, Juliette Kyner (previously Juliette Ward), and Dr. Shebani Sethi about the first-ever randomized controlled trial of a ketogenic diet intervention in individuals living with schizophrenia spectrum disorder
BITESIZE: New GLP-1 Study Raises Metabolic Health Questions
BITESIZE: New GLP-1 Study Raises Metabolic Health Questions Aug 13, 2026 05:25 Do GLP-1 medications improve metabolic health as much as they support weight loss? A new observational study in the Annals of Internal Medicine raises an important question about semaglutide, insulin discontinuation, type 2 diabetes, and what meaningful metabolic improvement may require.In this episode of Metabolic Mind, Dr. Bret Scher breaks down a real-world study of more than 9,000 veterans wit
Q&A: Insulin Resistance, Reaching Ketosis, Bone Density, and Rating Popular Keto Products
Q&A: Insulin Resistance, Reaching Ketosis, Bone Density, and Rating Popular Keto Products Aug 11, 2026 23:41 The questions around ketogenic therapy keep getting more layered, and your latest submissions reflect that. In this Metabolic Mailbag episode, Dr. Bret Scher and producer Erica Gerard tackle some of the most common questions about insulin resistance, ketosis, bone health, and a fun rapid-fire round on popular ketogenic products and practices.In this discussion, you'll learn:The difference between
Robyn Dobbins Reflects on Her Story in The Cholesterol Code
Robyn Dobbins Reflects on Her Story in The Cholesterol Code Aug 9, 2026 08:03 What does it look like to put bipolar II disorder into remission and become a voice of hope for others living with serious mental illness? Robyn Dobbins joins Hannah Warren from Metabolic Mind to reflect on how ketogenic therapy transformed her life, and what it was like to see her own story featured in The Cholesterol Code documentary.In this conversation, you'll learn:What it was like for Robyn
BITESIZE: Keto 101: Everything You Need to Know About Ketone Testing
BITESIZE: Keto 101: Everything You Need to Know About Ketone Testing Aug 6, 2026 05:24 How do you know if you're actually in ketosis? Should you test ketones? And if so, what's the best method: blood, breath, or urine?Dr. Bret Scher breaks down everything you need to know about ketone testing, including when testing matters, which tools are most accurate, and how to interpret your results based on your goals. Whether you're using a ketogenic diet for metabolic health, weight loss, o
Targeting Cancer Metabolism With Ketogenic Therapy and Fasting
Targeting Cancer Metabolism With Ketogenic Therapy and Fasting Aug 4, 2026 36:46 Could metabolic therapies become part of the future of cancer care?That question sits at the center of Dr. Bret Scher’s conversation with neurologist and researcher Dr. Matthew Phillips, whose recent study explored a metabolic approach in people with glioblastoma, one of the most aggressive forms of brain cancer.Rather than relying on a single intervention, the study combined a ketogenic diet, int
BITESIZE: JAMA Psychiatry Analysis: What 50 Studies Tell Us About Nutrition For Depression & Anxiety
BITESIZE: JAMA Psychiatry Analysis: What 50 Studies Tell Us About Nutrition For Depression & Anxiety Aug 2, 2026 06:45 Can a ketogenic diet help improve mood and reduce depressive symptoms?A new meta-analysis published in JAMA Psychiatry examined 50 different keto studies, totaling over 40,000 participants, that included depression and anxiety outcomes. The results of the review demonstrated a modest improvement in depression symptoms across different populations and diagnoses in both controlled and real-world sce
BITESIZE: New Study: Could GLP-1 Medications Be Reducing Physical Activity?
BITESIZE: New Study: Could GLP-1 Medications Be Reducing Physical Activity? Jul 30, 2026 07:27 Do GLP-1 medications like Ozempic reduce physical activity? Preliminary research suggests they might, raising important questions about how exercise should be supported alongside treatment.GLP-1 medications are helping many people achieve meaningful weight loss and metabolic improvements. At the same time, findings presented at the Endocrine Society’s annual meeting showed declines in daily steps
GLP-1s + Ketogenic Diet: The Future of Weight Loss?
GLP-1s + Ketogenic Diet: The Future of Weight Loss? Jul 28, 2026 28:41 Could a ketogenic diet and low-dose GLP-1 medications work better together? A new case series suggests they might, while highlighting a more personalized approach to metabolic health.GLP-1 medications have transformed obesity treatment, but they aren't the only tool available. In this interview, Dr. Bret Scher speaks with physician assistant Bill Jensen about a newly published case series explorin

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