Cardiac Consult: A Cleveland Clinic Podcast for Healthcare Professionals
A Cleveland Clinic podcast exploring heart, vascular and thoracic topics of interest to healthcare providers: medical and surgical treatments, diagnostic testing, medical conditions, and research, technology and practice issues.
Episodes
Talking Tall Rounds® Cardiac Sarcoidosis: Systematic Team Approach to Diagnosis & Management
In this excerpt from Tall Rounds®, Cleveland Clinic experts discuss imaging modalities that aid the diagnosis of cardiac sarcoidosis. The conversation explores diagnostic challenges, risk stratification, interpretation pitfalls and the role of serial imaging in assessing treatment response and guiding clinical decision-making.View other Tall Rounds programs. https://2207941.mediaspace.kaltura.com/
Evolving Strategies in Aortic Arch Repair
Eric Roselli, MD, and Patrick Vargo, MD, discuss how advances in open, hybrid and endovascular techniques are changing the treatment of aortic arch disease. They explore evolving approaches to aneurysms and dissections, innovations in brain protection and the role of specialized aortic centers in improving patient outcomes.Looking to refer a patient? Please reach out to our Physician Referral team
Management of Complex Aortic Valve Endocarditis
Milind Desai, MD, and Per Wierup, MD, discuss the evaluation and management of high-risk aortic valve endocarditis, including indications for urgent intervention and timing of surgery. They also review operative approaches to patients with heart failure, uncontrolled infection and embolic risk, highlighting the role of multidisciplinary expertise in complex endocarditis careLooking to refer a pati
Lepodisiran and the Emerging Role of Oxidized Phospholipids in Lipoprotein(a) Risk
Luke Laffin, MD, speaks with Steven Nissen, MD, about findings from the ALPACA trial evaluating lepodisiran and its effects on oxidized phospholipids and lipoprotein(a). They discuss the potential mechanisms linking lipoprotein(a) to cardiovascular risk and how ongoing phase 3 research may shape future management of patients with elevated lipoprotein(a).Looking to refer a patient? Please reach out
Talking Tall Rounds®: Updates on Less Invasive Cardiac Surgery
In this excerpt from Tall Rounds®, Gianluca Torregrossa, MD, discusses minimally invasive and totally endoscopic coronary artery bypass grafting (TECAB), highlighting procedural advances that enable multi-vessel revascularization through less invasive approaches. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.View the f
CTX310 and the Future of Gene Editing for Lipid Disorders
Steven Nissen, MD, and Luke Laffin, MD, discuss one-year follow-up data for CTX310, a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3 to treat lipid disorders. They review the sustained reductions in LDL cholesterol and triglycerides, and the potential role of one-time gene-editing therapies in cardiovascular prevention and lipid management.Read the article. https://consultqd.clevelandclinic.or
Evaluating Kylo-11 for Long-Acting Lipoprotein(a) Suppression
Steven Nissen, MD, and Ashish Sarraju, MD, discuss early clinical data on Kylo-11, a novel therapy that produced substantial reductions in lipoprotein(a) for up to one year after a single injection. Lowering lipoprotein(a), a genetically determined cardiovascular risk factor linked to atherosclerotic disease and aortic stenosis, remains an important focus for preventive cardiology. Learn about the
Robotic Approaches to Mitral and Aortic Valve Surgery
Marc Gillinov, MD, and Per Wierup, MD, discuss the evolution of robotic valve surgery, including advanced mitral valve repair techniques, patient selection and expanding applications for aortic valve and coronary procedures. They examine how enhanced visualization, instrument dexterity and a mature robotic program support excellent safety, durability and clinical outcomes.Looking to refer a patien
Infective Endocarditis Diagnosis and Management
Bo Xu, MD, and Shinya Unai, MD, discuss approaches to diagnosing and treating infective endocarditis, including indications for surgical intervention. The conversation highlights the role of multimodality imaging , individualized surgical planning and multidisciplinary care strategies to improve patient outcomes.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri
Expanding Coronary Revascularization With TECAB
Donna Kimmaliardjuk, MD, and Gianluca Torregrossa, MD, discuss the expanding role of robotic coronary artery bypass grafting, including total endoscopic coronary artery bypass (TECAB). They explore how a tailored surgical approach can improve long-term patient outcomes.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Stenting, Surgery and Hybrid Strategies for Coronary Disease
Faisal Bakaeen, MD, and Grant Reed, MD, discuss recent advances in the treatment of coronary artery disease, including drug-coated balloons, intravascular imaging, calcium modification and evolving PCI strategies. They also examine innovations in coronary artery bypass grafting, multi-arterial revascularization, minimally invasive and robotic techniques and the growing role of heart team collabora
Individualizing Aspirin Therapy in Preventive Cardiology
Luke J. Laffin, MD, and Vikas Sunder, MD, discuss the evolving role of aspirin in primary prevention, emphasizing individualized assessment of each patient's cardiovascular and bleeding risk. They explore how coronary artery calcium scores, lipoprotein(a) levels and comorbid conditions factor into aspirin recommendations in contemporary preventive cardiology practice.Looking to refer a patien
Robotic Lung Transplantation
Kenneth McCurry, MD, and Gregory Jones, MD, discuss the development of robotic lung transplantation, including candidate selection, operative considerations and early clinical experience with this minimally invasive approach. The conversation explores protocol development and future applications of robotic technology in lung transplantation.Looking to refer a patient? Please reach out to our Physi
A Multidisciplinary Approach to Limb Preservation
Courtney Hanak, MD, and Ravi Ambani, MD, discuss limb preservation and amputation prevention in patients with peripheral arterial disease and chronic limb-threatening ischemia. They review diagnostic approaches to assess perfusion and tissue viability, current revascularization strategies for limb salvage, wound care, factors that influence amputation decisions and emerging technologies shaping t
2026 Cholesterol Guidelines and What Clinicians Need to Know
Ashish Sarraju, MD, and Leslie Cho, MD, discuss key updates in the 2026 ACC/AHA cholesterol guidelines, including earlier LDL screening and integration of the PREVENT risk calculator. They explore clinical implications of Lp(a) testing, risk stratification and expanding therapeutic options to help patients achieve evidence-based lipid goals.Read more about the guidelines: https://consultqd.clevela
Post-Transplant Care and Complications in the First Year
Michael Zhen-Yu Tong, MD, and Sanjeeb Bhattacharya, MD, discuss the clinical management of heart transplant patients during the first year, including immunosuppression strategies, rejection surveillance and complication recognition. They also highlight evolving technologies, donor expansion and collaborative care approaches that are improving outcomes in advanced heart failure and transplantation.
Combined Ablation and Left Atrial Appendage Closure for Atrial Fibrillation
Oussama Wazni, MD, MBA, and Mohamed Kanj, MD, discuss the clinical rationale and outcomes behind combining atrial fibrillation ablation with left atrial appendage closure, including insights from the OPTION trial. They examine patient selection, procedural considerations and the impact of pulsed field ablation on safety, efficiency and long-term stroke prevention strategies.Looking to refer a pati
Optimizing PCI Outcomes in Complex Coronary Disease
Grant Reed, MD, and Laura Young, MD, discuss contemporary decision making in percutaneous coronary intervention, including patient selection, ischemia assessment and the role of medical therapy. They explore advances in imaging, plaque modification and hybrid revascularization strategies for complex coronary artery disease.Looking to refer a patient? Please reach out to our Physician Referral team
Sclerotherapy for Cosmetic and Symptomatic Spider Veins
Gayan De Silva, MD, and Kathleen Boyle, DO, discuss clinical evaluation and treatment of patients with spider veins, including differentiation from underlying venous and arterial disease and appropriate patient selection. Learn about technique considerations for foam and liquid sclerotherapy, expected outcomes, and long-term management.Looking to refer a patient? Please reach out to our Physician
CHIP and Cardiovascular Disease
Samir Kapadia, MD, and Ohad Oren, MD, examine clonal hematopoiesis of indeterminate potential (CHIP) and its role as a causal driver of cardiovascular disease. They discuss mutation-specific risk, implications for prevention and how CHIP informs cardiovascular genomics and precision medicine.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (E
AVANT GUARD Study: Early Ablation for Persistent Atrial Fibrillation
Walid Saliba, MD, and Oussama Wazni, MD, discuss the design and outcomes of the AVANT GUARD study evaluating first-line pulsed field ablation in drug-naive patients with persistent atrial fibrillation. The conversation explores efficacy endpoints, safety findings, and the implications for early rhythm control and disease progression.Read more about the study. https://consultqd.clevelandclinic.org/
Surgical Myectomy for Hypertrophic Cardiomyopathy
Milind Desai, MD, and Nicholas Smedira, MD, review contemporary diagnostic pathways and surgical decision making for hypertrophic cardiomyopathy. The discussion examines advanced imaging, outcomes from high volume centers, emerging surgical techniques and the evolving role of myosin inhibitors in obstructive and non-obstructive disease.Looking to refer a patient? Please reach out to our Physician
The Role of Smoking Cessation in Vascular Disease Management
Lee Kirksey, MD, and J. Eduardo Corso, MD, examine the clinical impact of smoking on peripheral artery disease, aneurysmal disease and outcomes after vascular intervention, with emphasis on risk modification and evidence-based decision-making. The discussion highlights practical strategies for integrating smoking cessation conversations into patient visits, screening considerations and how nicotin
Talking Tall Rounds®: Utility of Metabolic Exercise Testing in Cardiovascular Disease
This episode examines the clinical utility of cardiopulmonary exercise testing with emphasis on cardiac output, ventilatory efficiency, and metabolic responses to exercise. Cleveland Clinic experts discuss how CPET informs diagnosis, risk stratification and longitudinal management in pulmonary hypertension, complex cardiovascular disease and athletic populations.Meet the presenters: J. Emanuel Fin
Cardiac Surgical Support for High‑Risk Lead Extraction
Thomas Callahan, MD, and Shinya Unai, MD, discuss the role of cardiac surgical backup during transvenous lead extraction. The conversation examines risk stratification, preoperative planning and rescue strategies for vascular and cardiac injury. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.Learn more at leadconnecti
Diagnosis and Management of Pericarditis
Allan Klein, MD, and Deborah Kwon, MD, discuss contemporary guidance on pericarditis with emphasis on evolving diagnostic criteria, inflammatory syndromes and the role of multimodality imaging. The conversation explores risk stratification, medical treatment options and surgical decision-making in complex and recurrent disease.Looking to refer a patient? Please reach out to our Physician Referral
Integrating PFA Into Your Clinical Practice
Pasquale Santangeli, MD, PhD, and Arwa Younis, MD, discuss the clinical application of pulsed field ablation (PFA) for atrial fibrillation and ventricular arrhythmias. The conversation examines safety and efficacy benefits of PFA and the ongoing role of radiofrequency ablation in advanced electrophysiology practice.Attending the Heart Rhythm Society conference? Visit Cleveland Clinic physicians at
SURPASS-CVOT and the Case for Dual Incretin Therapy
Luke Laffin, MD, and Steven Nissen, MD, discuss findings from SURPASS-CVOT, including a secondary analysis evaluating broader cardiovascular and renal outcomes with dual GLP-1 and GIP agonist therapy compared with a first-generation GLP-1 agent. The conversation examines outcomes of the therapy on all-cause mortality and the clinical implications for treating patients with diabetes and high cardio
Monthly Therapy for Hypertension: Insights From the Phase II KARDINAL Trial
Steven Nissen, MD, and Luke Laffin, MD, discuss late-breaking data from the Phase II KARDINAL Trial evaluating Tonlamarsen, a once-monthly therapeutic for uncontrolled multidrug therapy. They review study design, blood pressure outcomes and the potential clinical role of long-acting injectable therapies to address adherence gaps in real-world hypertension management.View current clinical trials. h
Advancing Vascular Surgery Care Through Clinical Trials
Sean Lyden, MD, and Jon Quatromoni, MD, discuss the evolving landscape of vascular clinical trials, highlighting investigational therapies and device-driven innovations. Learn how these trials are shaping evidence-based decision-making, expanding minimally invasive options and influencing future standards of care for aortic, carotid, peripheral arterial and venous disease. View current clinical tr
Aortic Valve Repair for Aortic Regurgitation
Lars Svensson, MD, PhD, and Milind Desai, MD, MBA, discuss contemporary evaluation and management of aortic valve regurgitation, emphasizing advanced imaging and optimal timing of intervention. They examine valve repair versus replacement, durability outcomes and lifetime management considerations at a high-volume valve center.Looking to refer a patient? Please reach out to our Physician Referral
New Comprehensive Care Model for the Woman Athlete
Women’s cardiologist Tamanna Singh, MD, and sports medicine physician Marie Schaefer, MD, introduce the WISER (Women's Integrated Sports, Exercise and Research), a multidisciplinary program addressing the cardiovascular, musculoskeletal, and psychosocial needs of women athletes across the lifespan. They outline how its cross‑institute model integrates cardiology, orthopedics, nutrition, psych
Coarctation of the Aorta: Repair Strategies and Outcomes
Eric Roselli, MD, and Patrick Vargo, MD, discuss the contemporary management of aortic coarctation in adults, including late complications, reintervention strategies, and evolving endovascular and hybrid approaches informed by decades of institutional experience. View the research: Late Complications of Aortic Coarctation Repair Can Be Safely Treated https://consultqd.clevelandclinic.org/late-co
Cardio‑Obstetrics and Heart Failure: Preconception to Postpartum Management
Maria Mountis, DO, and Karlee Hoffman, DO, explore the complexities of pregnancy and parenthood in heart transplant recipients or those living with heart failure, highlighting multidisciplinary cardio‑obstetrics care. These heart failure experts explore the nuanced decision‑making required to balance maternal health, fetal safety and long‑term transplant outcomes, emphasizing the importance of pre
The Future of Cardiac Care: Genomic Insights and Precision Therapies
The new Haslam-Bailey Family Section of Cardiovascular Genomics and Precision Medicine is integrating genomic data into cardiovascular risk assessment, diagnosis and treatment. Samir Kapadia, MD, and Krishna Aragam, MD, discuss practical applications of genetic testing and emerging gene‑targeted therapies to enable more proactive and precise patient care.Looking to refer a patient? Please reach ou
Advances in the Diagnosis and Management of Inherited Arrhythmias
Oussama Wazni, MD, MBA, and Jeffery Courson, DO, examine the evaluation and management of inherited arrhythmias and genetic cardiomyopathies. They discuss diagnostic strategies like genetic testing and advanced imaging, and the role of multidisciplinary care in precision medicine. The conversation also highlights evolving therapies, including individualized pharmacologic approaches and emerging ge
Cleveland Clinic's New Cardiovascular Center on Aging
Venugopal Menon, MD, and Abdulla Damluji, MD, discuss the emerging subspecialty of cardiovascular aging and the growing need to tailor cardiovascular care for older adults. They explore how integrating geriatric expertise into cardiovascular practice can improve diagnostic accuracy, individualize therapy and optimize outcomes for this rapidly expanding patient population.Read more about the Cardi
Structured Follow‑Up for Aortic Valve Replacement Success
Amar Krishnaswamy, MD, and Marijan Koprivanac, MD, discuss contemporary follow‑up strategies after TAVR and SAVR, highlighting advances in minimally invasive and robotic surgical approaches that significantly reduce recovery time and postoperative pain. They outline evidence‑based recommendations for cardiac rehabilitation and structured imaging surveillance, emphasizing the critical role of timel
New Guidelines on Acute Coronary Syndromes: Key Takeaways for Cardiologists
Explore the latest ACC/AHA guidelines on acute coronary syndromes with co-authors Venugopal Menon, MD, and Jacqueline Tamis-Holland, MD, joined by Donna Kimmaliardjuk, MD. This discussion covers key updates, including unified STEMI/non-STEMI recommendations, heart team decision-making for multivessel disease, evolving strategies for dual antiplatelet therapy, and the role of mechanical circulatory
Gut Microbiome and TMAO as Predictors of Abdominal Aortic Aneurysm Progression
Stanley Hazen, MD, PhD, and Scott Cameron, MD, PhD, discuss emerging evidence linking gut microbiome-derived TMAO to abdominal aortic aneurysm development and progression. They explore its role as both a causative factor and a biomarker, review current risk stratification strategies and highlight future therapeutic approaches aimed at reducing TMAO levels to improve vascular outcomes.Learn more ab
Transcatheter Pulmonary Valve Therapy: Lifetime Management Strategies
Hani Najm, MD, and Joanna Ghobrial, MD, discuss the evolving role of transcatheter pulmonary valve implantation in lifetime management of congenital heart disease patients. They explore patient selection, valve durability, imaging strategies for early detection of HALT or HAM and the collaborative heart team approach that optimizes outcomes.Looking to refer a patient? Please reach out to our Physi
Ventricular Septal Rupture Post-MI: Evolving Strategies for Optimal Outcomes
Venugopal Menon, MD, Director of the Coronary ICU, and Michael Tong, MD, cardiothoracic surgeon specializing in advanced heart failure, discuss contemporary management of post-infarction ventricular septal rupture, a rare but serious complication. They review the role of early transfer to high-volume centers and why definitive surgical closure remains the gold standard. Learn about the impact of t
Optimizing Outcomes for Lung Failure Treatment and Transplant
Kenneth McCurry, MD, and Marie Budev, DO, share Cleveland Clinic’s multidisciplinary approach to managing end-stage lung disease and advancing lung transplantation. They discuss innovations such as ex vivo lung perfusion (EVLP), ECMO bridging, and strategies for expanding donor and recipient criteria, including complex and multi-organ cases. The episode also highlights ongoing research and clinica
Cleveland Clinic's New Cardioimmunology Center
Samir Kapadia, MD, Chairman of Cardiovascular Medicine at Cleveland Clinic, and David Zidar, MD, PhD, an interventional cardiologist and immunologist, introduce Cleveland Clinic’s Cardioimmunology Center, a new initiative focused on the intersection of immune pathways and cardiovascular disease. They discuss how immune system activity can influence heart health and discuss innovative approaches to
Guidelines and Innovations Shaping Peripheral Artery Disease Treatment
Lee Kirksey, MD, Aravinda Nanjundappa, MBBS, MD, and G. Jay Bishop, MD, discuss a multidisciplinary approach to peripheral artery disease (PAD) management. They explore evidence-based strategies including early detection, optimal medical therapy, supervised exercise programs and advanced endovascular and surgical interventions, emphasizing team-based care and longitudinal follow-up for improved ou
American College of Cardiology Concise Clinical Guidance on Pericarditis
Allan Klein, MD, and Tom Kai Ming Wang, MBChB, discuss the 2025 ACC Concise Clinical Guidance on pericardial disease. They explore updated diagnostic criteria, the role of multimodality imaging and a shift toward IL-1 blockers for recurrent pericarditis. Learn practical strategies to optimize patient outcomes and avoid misdiagnosis or undertreatment, along with insights on surgical options and eme
Expertise in Valve-Sparing Aortic Root Replacement
Lars Svensson, MD, PhD, and Xiaoying Lou, MD, share a deep dive into valve-sparing aortic root surgery, an advanced technique that preserves the patient’s native valve while treating aortic aneurysms.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Research: Gene Editing for Lifelong Lipid Control
Steven Nissen, MD, and Luke Laffin, MD, discuss a groundbreaking phase 1 trial of a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3. They explore its potential as a one-time treatment to significantly lower LDL cholesterol and triglycerides, with promising safety and efficacy data that could reshape lipid management.Learn more about C5 Research at Cleveland Clinic.https://my.clevelandclinic.org
Lifelong Mitral Valve Management After Repair
A. Marc Gillinov, MD, and Tarek Malas, MD, discuss the long-term benefits of mitral valve repair for patients with degenerative mitral valve disease. They explore surgical decision-making, robotic techniques and post-operative recovery strategies like cardiac rehab that support lifelong valve function and optimal patient outcomes. Looking to refer a patient? Please reach out to our Physician Refer
Innovations in Ex Vivo Lung Perfusion and Multi-Organ Transplantation
Kenneth McCurry, MD, and Marie M. Budev, DO, discuss Cleveland Clinic’s leadership in lung and multi-organ transplantation, highlighting innovations like ex vivo lung perfusion (EVLP) and the collaborative care model that supports complex transplant cases. They also acknowledge Lung Transplant Awareness Day, a national initiative aimed at increasing education about end-stage lung disease.Looking t
Managing Obesity in Adults With Heart Failure
Tamanna Singh, MD, and Amanda Vest, MBBS, discuss the relationship between obesity and heart failure. They discuss multidisciplinary strategies, including lifestyle interventions and pharmacologic therapies like GLP-1 receptor agonists for managing patients across the spectrum of heart failure. Learn emerging clinical research regarding obesity and heart failure from Cleveland Clinic experts. Look
Innovations in Multi-Arterial and Total Arterial Bypass Grafting
Donna Kimmaliardjuk, MD, and Faisal Bakaeen, MD, explore the latest in multi-arterial coronary artery bypass grafting (CABG). They discuss patient selection, surgical techniques and long-term outcomes supported by optimal medical therapy. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Expertise in Mechanical Circulatory Support Device Use
When a heart is weak after a heart attack, cardiac arrest or surgery, mechanical circulatory support (MCS) can help the heart function while it heals or assist patients long-term. Cleveland Clinic experts discuss MCS devices, specifically the Impella percutaneous left ventricular assist device (LVAD) and extracorporeal membrane oxygenation (ECMO). Looking to refer a patient? Please reach out to o
Women and Heart Disease: Sex-Based Differences in Heart Failure
Amanda Vest, MBBS, explores sex-based differences in heart failure, focusing on biological and social factors that influence disease development, treatment response and outcomes in women. She highlights disparities in risk factors, access to care and clinical trial representation that can influence heart failure outcomes. Looking to refer a patient? Please reach out to our Physician Referral team
Women and Heart Disease: Clinical Presentation and Treatment Gaps Among Women with PAD
Scott Cameron, MD, highlights the underdiagnosis and undertreatment of peripheral artery disease (PAD) in women. He discusses diagnostic challenges and emphasizes the need for improved screening, female-specific guidelines and more inclusive research to address disparities in care.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.
Women and Heart Disease: The Association Between Females and AFib
Women are more likely than men to experience atrial fibrillation symptoms. Mohamed Kanj, MD, discusses gender-based differences in atrial fibrillation treatment, including rate control, rhythm control and anticoagulation. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Innovations in Carotid Stenting
Ravi Ambani, MD, and Aravinda Nanjundappa, MBBS, MD, discuss Cleveland Clinic’s leadership and progress in treating carotid artery disease. Learn how multidisciplinary teams are transforming care with new research on medical and surgical therapies. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Treating Chronic Thromboembolic Pulmonary Hypertension
Chronic thromboembolic pulmonary hypertension (CTEPH) is a type of pulmonary hypertension caused by chronic blood clots in the lungs. It is an under-recognized condition, but with accurate imaging and quality treatment, it can often be cured. Gustavo Heresi, MD, and Michael Tong, MD, discuss diagnosis, medical therapy and surgical options for people with CTEPH.Looking to refer a patient? Please re
Expertise in Mitral Valve Surgery
When treating mitral valve disease, a surgeon must decide whether to repair or replace a valve. Cleveland Clinic experts discuss robotically-assisted surgery, reoperations and the outcomes a patient can expect from surgery at Cleveland Clinic.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.Meet the presenters:Marc Gillin
A Discussion on Marfan Syndrome and Connective Tissue Disorders - Part II
Connective tissue disorders like Marfan, Loeys-Dietz, and Ehlers-Danlos syndromes can affect the function of the heart and aorta. Cleveland Clinic experts discuss surgical options, recovery and expected outcomes for those with connective tissue disorders.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.Meet the Presenters
A Discussion on Marfan Syndrome and Connective Tissue Disorders - Part I
Connective tissue disorders like Marfan, Loeys-Dietz, and Ehlers-Danlos syndromes can affect the function of the heart and aorta. Cleveland Clinic experts discuss the diagnosis of these genetic conditions and indications for heart and aorta treatment in patients with connective tissue disorders in part one of this two-part series.Meet the Presenters:Lars Svensson, MD, PhD Chief of the Sydell and A
Update on Vascular Medicine Clinical Trials
G. Jay Bishop, MD, and Aravinda Nanjundappa, MBBS, MD, explore Cleveland Clinic’s latest advances in vascular medicine, from research on aortic aneurysm biomarkers to innovative treatments for pulmonary embolism, hypertension, and peripheral artery disease. Learn how multidisciplinary teams are transforming care with new research on cutting-edge therapies. Looking to refer a patient? Please reach
TANDEM Insights: Trial Results and Clinical Implications
Learn about the promising results of a fixed-dose combination therapy trial that achieved up to a 50% reduction in LDL cholesterol. Steven Nissen, MD and Ashish Sarraju, MD discuss how this CETP inhibitor-based therapy compares to monotherapies, its potential role in treating high-risk cardiovascular patients, and what it could mean for the future of hyperlipidemia management.Looking to refer a pa
Treating AFib After Ablation
Persistent or recurrent atrial fibrillation (AFib) following ablation remains a clinical challenge, especially when it occurs more than three months after an ablation. Expert Cleveland Clinic electrophysiologists discuss the causes for recurrent AFib and review current management strategies, including redo ablation and surgical intervention. Meet the presenters:Oussama Wazni, MD, MBA, Section Head
Expertise in Structural Heart Disease
Structural heart disease encompasses a range of abnormalities affecting the heart’s valves, chambers, and muscle. At Cleveland Clinic, our team brings deep expertise in the diagnosis and interventional management of these complex conditions—particularly valvular heart disease.In this discussion, expert Cleveland Clinic cardiologists explore the latest advances in transcatheter therapies, cutting-e
Managing Aortic Aneurysms
When an aortic aneurysm occurs, a multidisciplinary team of experts can provide the best care for the patient. Francis (Frank) Caputo, MD, and Marijan Koprivanac, MD, discuss aortic aneurysms and the team-based approach to treating these complex conditions at Cleveland Clinic.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.24
Experience and Outcomes in Bicuspid Valve Repair - Part II
Bicuspid aortic valve is a common heart condition where the aortic valve has only two leaflets instead of the normal three. In part two of this two-part series, Lars Svensson, MD, PhD, and Brian Griffin, MD, discuss surgical techniques for bicuspid valve disease, surgical outcomes and the referral process. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8
Experience and Outcomes in Bicuspid Valve Repair - Part I
Bicuspid aortic valve is a common heart condition where the aortic valve has only two leaflets instead of the normal three. In part one of this two-part series, Lars Svensson, MD, PhD, and Brian Griffin, MD, discuss treatment options for managing bicuspid valve disease, including timing and indications for surgery.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - F
ACC 2025 Research Highlights
Venugopal Menon, MD, Section Head of Clinical Cardiology , spotlights new Cleveland Clinic research presented at ACC 2025. Explore the highlights of six studies on topics like antiplatelet therapy, fungal endocarditis, mechanical circulatory support, and the use of AI for clinical trial enrollment. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5
Advancements in HCM: From AI Diagnosis to Gene Therapy
Cleveland Clinic is transforming hypertrophic cardiomyopathy (HCM) care through new clinical trial innovations. Milind Desai, MD, MBA, recaps two recent studies that analyzed the use AI for the diagnosis of HCM and gene therapy for treatment.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Innovative Heart Failure Therapies and Clinical Trials
Cleveland Clinic's dedication to research and a team of teams approach puts the Heart, Vascular and Thoracic Institute at the forefront of heart failure care. Amanda Vest, MBBS, and Edward Soltesz, MD, discuss ongoing clinical trials and the newest clinical practices to provide the best outcomes for patients with heart failure. Meet the Presenters: Amanda Vest, MBBS, Section Head of Heart Fai
Robotics Volumes and Outcomes
Siva Raja, MD, PhD, provides an update on volumes and outcomes for robotically-assisted thoracic surgery at Cleveland Clinic. https://my.clevelandclinic.org/staff/17512-siva-rajaLearn more about the Department of Thoracic Surgery. https://my.clevelandclinic.org/departments/heart/depts/thoracic-surgeryLooking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. -
LVAD as a Destination Therapy
For patients with heart failure, a left ventricular assist devices (LVAD) can help the body meet its circulatory needs. Pavan Bhat, MD, and Michael Tong, MD, discuss LVAD as a bridge between medical therapy and a heart transplant, or as a destination therapy for those who aren't transplant candidates.Learn more about the Kaufman Center for Heart Failure Treatment and Recovery. https://my.clev
Pulmonary & Esophageal Volumes and Outcomes
Daniel Raymond, MD, provides an update on volumes and outcomes for the pulmonary and esophageal surgery programs at Cleveland Clinic. Learn more about the Department of Thoracic Surgery. https://my.clevelandclinic.org/departments/heart/depts/thoracic-surgeryLooking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Lung Transplantation Volumes and Outcomes
Kenneth McCurry, MD, provides an update on lung transplant volumes and outcomes for the Department of Thoracic and Cardiovascular Surgery at Cleveland Clinic.View the case study and patient story Dr. McCurry shared.Learn more about the Department of Thoracic Surgery. https://my.clevelandclinic.org/departments/heart/depts/thoracic-surgeryLooking to refer a patient? Please reach out to our Physician
LAAC and Ablation: Results from the OPTION Trial
The OPTION clinical trial compared left atrial appendage closure to continued oral anticoagulation in patients at risk of stroke after undergoing atrial fibrillation (AFib) ablation. Oussama Wazni, MD and Mohamed Kanj, MD discuss the findings of the trial and the future of AFib care. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 85
Reoperative Surgery Volumes and Outcomes
Shinya Unai, MD, provides an update on reoperation volumes and outcomes for the Department of Thoracic and Cardiovascular Surgery at Cleveland Clinic.Learn more about the Department of Thoracic and Cardiovascular Surgery. https://my.clevelandclinic.org/departments/heart/depts/cardiovascular-surgeryLooking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p
Thoracic & Cardiovascular Surgery Volumes and Outcomes
Marc Gillinov, MD, provides an update on volumes and outcomes for the Department of Thoracic and Cardiovascular Surgery at Cleveland Clinic.Learn more about the Department of Thoracic and Cardiovascular Surgery.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.
Lorundrostat: Results from Advance-HTN Phase 2 Study
Luke Laffin, MD, shares the findings from a late breaker he presented at ACC 2025. Lorundrostat is an investigational drug found to significantly lower 24-hour blood pressure among patients with uncontrolled and resistant hypertension. Learn more about C5 Research at Cleveland Clinic.https://my.clevelandclinic.org/research/c5researchLooking to refer a patient? Please reach out to our Physician Ref
Lepodisiran: A Novel Therapy to Reduce Lipoprotein(a)
Steven Nissen, MD, shares the findings from a late breaker he presented at ACC 2025. Lepodisiran is a small interfering RNA that targets lipoprotein(a) levels, lowering a patient's risk for atherosclerosis and aortic stenosis. https://my.clevelandclinic.org/staff/1185-steven-nissenLearn more about C5 Research at Cleveland Clinic.https://my.clevelandclinic.org/research/c5researchLooking to re
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