HemeTalks: Conversations in Hematology Education
HemeTalks: Conversations in Hematology Education is an American Society of Hematology (ASH) podcast for community hematologists, advanced practice providers, and trainees. Through engaging storytelling and case-based discussions with guests ranging from early-career professionals to leading experts, the podcast offers practical strategies that make complex hematology topics accessible and relevant at every career stage. Its mission is to support the educational needs of its audience through high-quality, clinically focused content.
Episodes
From Aplastic Anemia to PNH: The Patient Perspective
In this episode of HemeTalks, we are joined by Ms. Elise Burton, who shares her experience living with paroxysmal nocturnal hemoglobinuria (PNH). Elise describes how her journey began several years earlier with a diagnosis of aplastic anemia, before her condition was later recognized as PNH after she developed evidence of unexplained hemolysis. She walks through her treatment journey, inc
Caring for Young Adults with Sickle Cell Disease
Dr. Cece Calhoun (Yale School of Medicine) joins Heme Talks to discuss one of the most vulnerable moments in sickle cell care: the transition from pediatric to adult management. Using a real case of a 24-year-old with hemoglobin SC disease re-establishing care after a lapse, Dr. Calhoun walks through how to build trust with adolescent and young adult patients, why sickle cell disease is a
From Steroids to Cure: A Modern Approach to Immune Thrombocytopenic Purpura (ITP)
Immune thrombocytopenic purpura (ITP) is a diagnosis of exclusion but treating it is anything but straightforward. In this episode, Dr. Adam Cuker (University of Pennsylvania) joins us to break down how the management of ITP is evolving in real time, from diagnostic pitfalls to a preview of the newly released ASH ITP guidelines. We cover first-line corticosteroid strategies, when to add I
Blasting Through B-ALL: Modern Management from Induction to CAR T
In this episode of HemeTalks, we dive into the evolving landscape of B-cell acute lymphoblastic leukemia (B-ALL) management with Dr. Adam DuVall. We begin with newly diagnosed disease, discussing which patients qualify for asparaginase containing pediatric inspired induction regimens. We then shift to the relapsed/refractory setting, exploring the roles of blinatumomab and inotuzumab ozog
Peripheral T-Cell Lymphoma: Navigating Diagnosis, Relapse, and Emerging Treatment Strategies
Episode Description:In this episode of HemeTalks, we are joined by Neha Mehta-Shah, MD, MSCI, Associate Professor of Medicine at Washington University in St. Louis, to discuss the evolving management of peripheral T-cell lymphomas (PTCL), with a focus on differences by histologic subtype. Through a case-based discussion, Dr. Mehta-Shah explores the diagnostic challenges of PTCL, including
Warm Autoimmune Hemolytic Anemia: The Patient Perspective
In this episode of HemeTalks, we are joined by Mr. Sean Powell as he shares his experiences as a former patient and now patient advocate for a rare blood disorder known as warm autoimmune hemolytic anemia (wAIHA). Sean shares his story of how he was diagnosed, the initial management, drug toxicities, and subsequent investigations that he underwent. Our patient advocate episodes highlight
Warm Autoimmune Hemolytic Anemia: Challenges, Choices, and New Therapies
In this episode of Heme Talks, we are joined by Allyson Pishko, MD, MSCE, Classical Hematologist and Assistant Professor of Medicine at the University of Pennsylvania, to discuss a rare blood disorder known as warm autoimmune hemolytic anemia (wAIHA). In this episode, Dr. Pishko shares her approach to diagnosis and management of this disorder, and how she approaches discussions about this
Unfolding Amyloid: A Patient Perspective
In this episode of Heme Talks, we are joined by Dr. Sai Jambunathan as she shares her experiences with the diagnosis and management of a rare blood disorder known as AL amyloidosis. As a patient herself, listeners will gain insights into the complex initial workup and what the treatment journey is like for patients with this condition. Our patient advocate episodes highlight the importanc
Re‑Thinking “Normal”: Absolute Neutrophil Count by Duffy Status
Join Dr. Maureen Achebe and Dr. Lauren Merz for an in‑depth exploration of the Absolute Neutrophil Counts (ANC) by Duffy Status project, a multicenter effort to define what “normal” ANC and white blood cell counts (WBC) look like in people with the erythrocyte Duffy null variant. Using data from 23 sites across the United States, the project established Duffy null-specific ANC and WBC ref
Multiple Myeloma Care: Timing, Teamwork, Treatment
Multiple myeloma care is evolving faster than ever, with new therapies, treatment strategies, and possibilities emerging at an unprecedented pace. In this episode, hematologist Dr. Devarakonda and Kathy Giusti, founder of the Multiple Myeloma Research Foundation, come together for a candid, practical conversation about what this rapid progress means for patients, caregivers, and providers
Atención del Mieloma Múltiple: Oportunidad, Trabajo en Equipo y Tratamiento
La atención del mieloma múltiple está evolucionando más rápido que nunca, con la aparición de nuevas terapias, estrategias de tratamiento y posibilidades a un ritmo sin precedentes. En este episodio, el hematólogo Dr. Devarakonda y Kathy Giusti, fundadora de la Multiple Myeloma Research Foundation (Fundación para la Investigación del Mieloma Múltiple), se reúnen en una conversación sincer
TTP Today: Diagnosis, Management & Evolving Therapies
TTP is a hematologic emergency that demands immediate recognition and treatment to prevent fatal outcomes. In this HemeTalks episode, Dr. Yazan Abou-Ismail and Dr. Kolton Smith discuss the diagnostic hallmarks, therapeutic advances, and follow-up strategies for patients with TTP.Through the lens of a clinical case, they explore the impact of caplacizumab, the importance of ADAMTS13 testin
Approaching MDS: Advances in Diagnostics, Therapeutics and Monitoring
Join us for an insightful discussion on myelodysplastic neoplasms (or MDS) with Drs. DeZern and Mack as we review the current standards in diagnosis of MDS using cutting edge molecular techniques. This marrow failure syndrome requires thoughtful and accurate diagnosis to ensure appropriate risk assessment for clinical decision making. We will then review relevant therapeutic choices and h
New Horizons in Smoldering Multiple Myeloma
Join Professor Brea Lipe and Professor Sagar Lonial as they discuss the changing treatment landscape of smoldering multiple myeloma (SMM). With a recently approved treatment for high-risk SMM, knowing how to differentiate and manage SMM compared with monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) has never been more crucial. Professors Lipe and Lonial
Interpreting Abnormal SPEP – Is It Just MGUS?
Monoclonal gammopathy of undetermined significance (MGUS) is a common but often confusing finding on serum protein electrophoresis (SPEP) reports. In this HemeTalks episode, Drs. Rahma Warsame and Jason Chen discuss how to interpret abnormal SPEP results, evaluate patients with suspected MGUS, and differentiate between benign and concerning findings. Using real-world cases, they highlight
Sticky Situations: The Role of Thrombophilia Testing in VTE Management
In this episode, Drs. Ronak Mistry and Jori May discuss the challenging decision of when to test for inherited thrombophilias and how results inform anticoagulation management. The use of thrombophilia testing has long been debated in the hematology community, due in large part to limited data and the complexity of estimating recurrent thrombotic risk. Through the case of a 36-year-old wo
Lost in Translation: The aHUS Experience
In this episode of HemeTalks, Alyssa Deffenbaugh and Dr. Toyosi Onwuemene explore the challenges of diagnosing, managing, and living with atypical hemolytic uremic syndrome (aHUS). Listeners will gain insight from a patient advocate and individual living with aHUS, as well as a physician who supports patients through diagnosis and ongoing management. Together, they highlight the importanc
Inclusion of those with those with Duffy-null Associated Neutrophil Count (DANC) in Clinical Trials
Join us for an important conversation with Dr. Andrew Hintel and Dr. Lauren Merz as we explore how the Duffy null phenotype shapes absolute neutrophil count (ANC) and what this means for clinical care and trial design. Although common among individuals of African, Middle Eastern, and North African ancestry, the Duffy null phenotype is often misunderstood, leading to unnecessary procedures
Thalassemia in Pediatric Hematology
Join us for a vital conversation on thalassemia in pediatric hematology with Drs. Sujit Sheth and Ashutosh Lal. Thalassemia is one of the most common inherited blood disorders in children globally, especially in populations from the Mediterranean, Middle East, South Asia, and Africa. This episode explores the different types of thalassemia, strategies for early diagnosis, the importance o
Bridging the Gap: Coordinating CAR-T Care Between Community and Academic Practices
Join Drs. Caimi and Sdrimas for a focused discussion on the coordination of CAR-T therapy between academic and community practices. As CAR-T use expands, ensuring seamless communication and shared responsibilities between care teams is essential. Using a real-world patient case, this episode explores how to navigate logistics, manage toxicities, and support patients in both settings—deliv
Relapsed Myeloma: Navigating Post-BCMA Therapy Failure
Join us for an insightful discussion with Drs. Natalia Neparidze and Saad Z. Usmani as we explore treatment strategies for relapsed multiple myeloma following BCMA-targeted therapy failure. With CAR T-cell therapy and bispecific antibodies revolutionizing myeloma treatment, clinicians are now faced with new challenges as patients relapse after BCMA-directed therapies. Through the case of
Hereditary Hemorrhagic Telangiectasia: Diagnosis, Management, and Advances
Join us for an insightful discussion on hereditary hemorrhagic telangiectasia (HHT) with Drs. Hanny Al-Samkari and Adrienne Hammill as we explore the challenges in diagnosing and managing this genetic disorder. HHT is characterized by the development of bleeding nasal and gastrointestinal telangiectasias, as well as arteriovenous malformations (AVMs) in visceral organs and the central ner
Thrombotic Microangiopathy in Pregnancy: Challenges and Advances
Join us for an insightful discussion on thrombotic microangiopathy (TMA) in pregnancy with Drs. Richard Burwick and Shruti Chaturvedi as we navigate the complexities of diagnosing and managing hypertensive disorders in pregnancy. These conditions often present overlapping clinical and laboratory features, making timely and accurate intervention challenging. Through the case of a 32-year-o
Unveiling Von Willebrand Disease: Advances in Diagnosis and Treatment
In this episode of HemeTalks, Dr. Jill Johnsen and Dr. Michelle Sholzberg explore Von Willebrand Disease (VWD), the most common inherited bleeding disorder. The discussion delves into the disease's pathophysiology, diagnostic challenges, and the latest advancements in treatment. Learn about the complexities of diagnosing VWD, and discover we are working together to improve outcomes. This
Battling Invisible Enemies: Toxic Exposures and Hematologic Cancers in Military Members
Join us on HemeTalks as Dr. Christin DeStefano and Dr. Drew Helmer discuss the impact of military toxic exposures on the development of hematologic malignancies, including leukemia, lymphoma, and myeloma. Learn about the challenges of diagnosing and treating these cancers, advancements in research, and strategies for improving care for military members and veterans. Learning Objectives:Di
Iron-Clad Health: Tackling Iron Deficiency in Women
Dr. Anjlee Mahajan (@anjleemd), Dr. Angela Weyand (@acweyand) and Dr. Michelle Sholzberg (@sholzberg ) delve into how current standards of care may contribute to disparities in the diagnosis and treatment of iron deficiency, particularly among female patients, as well as sharing compelling valuable insights into important considerations in addressing and overcoming these challenges to adv
The Road to Inclusion: Navigating Challenges to Haploidentical Donor Transplants
Dr. Shakira Grant and Dr. Irum Kahn explore the fascinating history of stem cell transplants, beginning with its origins and milestones in the field such as the evolution of haploidentical transplants, a groundbreaking approach that has expanded donor options and improved outcomes for patients from diverse backgrounds. They then examine the clinical implications of these advancements, the
Blood for All: Clinical Impacts of Diverse Donor Pools
Dr. Rahma Warsame (@RWarsameMD) sits down with Dr. Margo Rollins to explore the critical clinical importance of diverse blood donors and unique challenges faced in recruiting and retaining a diverse donor pool. They then delve into practical strategies and opportunities to overcome these barriers. Join us to gain valuable insights into how enhancing donor diversity can significantly impro
Advancing Sickle Cell Disease Care: A conversation between cellular therapy & BMT providers
Are you a healthcare professional seeking clarity on the evolving treatments for sickle cell disease (SCD)? In this 20-minute episode, experts from cellular therapy and bone marrow transplantation (BMT) explore key updates in SCD care, including curative therapies, gene-editing innovations, and BMT approaches. They address practical challenges in integrating these treatments into practice
Inside ASH 2024: Insights from the Education Program Co-Chairs
Join us for an insightful podcast episode featuring the Co-Chairs of the upcoming 2024 ASH Annual Meeting, where we explore the planning process and strategic goals that shaped this year’s program. Discover how the Co-Chairs ensured the Education Program meets the diverse needs of the hematology community, and the unique challenges faced during the planning and how they were overcome. Gai
Blood Transfusion Safety: TRALI vs TACO
Join us as we explore blood transfusion safety, focusing specifically on Transfusion-Related Acute Lung Injury (TRALI) and Transfusion-Associated Circulatory Overload (TACO). Tailored for general hematologists with a foundational understanding of transfusion medicine, this session delves into the pathophysiology, clinical presentation, diagnostic criteria, and management strategies for TR
Advancing Sickle Cell Disease Care: Navigating Gene Therapy
Are you a hematologist or a generalist provider seeking clarity on how to best counsel patients with sickle cell disease (SCD) who are interested in gene therapy? Join us for a podcast session focused on important patient considerations for gene therapy, tailored for SCD providers and clinicians. This session aims to provide practical insights to facilitate clear communication between pro
Updates in Thalassemia: New Challenges and Novel Treatment Approaches
Speakers: Alexis Thompson, MD, and Sujit Sheth, MDDescription:For general hematologists with a foundational understanding of thalassemia, this episode discusses the changing demographics due to immigration and refugee resettlement. It covers the diagnosis process from newborn screening to older individuals, emphasizing genetic testing due to numerous mutations and varied phenotypes. The i
Multiple Myeloma in Underrepresented Populations: Treatment Considerations
Dr. Azam Farooqui (@azamfarooqui ) and Dr. Monique Hartley-Brown (@DrMHB1) discuss therapeutic considerations regarding current and emerging agents for patients with multiple myeloma from underrepresented racial and ethnic groups. Coming Soon!Prepare to enhance your knowledge through the IMPACT II online learning module on ASH Academy On Demand! Participants will develop an increased abil
Multiple Myeloma in Underrepresented Populations: Survival Outcomes
Dr. Azam Farooqui (@azamfarooqui )and Dr. Sikander Ailawadhi answer the question: Why do we need earlier diagnosis and intervention in patients with multiple myeloma from underrepresented racial and ethnic groups? Coming Soon!Prepare to enhance your knowledge through the IMPACT II online learning module on ASH Academy On Demand! Participants will develop an increased ability to identify v
Multiple Myeloma in Underrepresented Populations: Clinical Risk
Dr. Azam Farooqui (@azamfarooqui) and Dr. Urvi Shah (@UrviShahMD) identify factors that impact outcomes for patients with multiple myeloma from underrepresented racial and ethnic groups. Coming Soon!Prepare to enhance your knowledge through the IMPACT II online learning module on ASH Academy On Demand! Participants will develop an increased ability to identify variations in factors influe
IMPACT II: Impacting Multiple Myeloma in All CommuniTies
Season 2: IMPACT II: Impacting Multiple Myeloma in All CommuniTiesUnlock insights into the treatment of multiple myeloma within underrepresented racial and ethnic populations with this series of three enlightening podcast episodes. Join experts from both academic and community oncology settings as they dive into critical aspects of clinical risk, survival outcomes, and treatment considera
GENOM: Myelodysplastic Syndromes and Clonal Hematopoiesis
Dr. Michael Diaz (@mdiazoncmd) and Dr. Namrata Chandhok (@NamrataChandhok) discuss the importance of genomic testing and how to understand and interpret test results when treating patients with myelodysplastic syndromes and clonal hematopoiesis. They also discuss the importance of selecting appropriate therapeutic agents to manage hematologic malignancies. This project is a collaboration
GENOM: Acute Myeloid Leukemia
Dr. Michael Diaz (@mdiazoncmd) and Dr. James Blachly (@jamesblachly) discuss the importance of genomic testing and how to understand and interpret test results when treating patients with acute myeloid leukemia. They also discuss the importance of selecting appropriate therapeutic agents to manage hematologic malignancies. This project is a collaboration between the American Society of He
GENOM: Acute Lymphoblastic Leukemia
Dr. Michael Diaz (@mdiazoncmd) and Dr. Emily K. Curran (@ECurranMD) discuss the importance of genomic testing and how to understand and interpret test results when treating patients with acute lymphoblastic leukemia. They also discuss the importance of selecting appropriate therapeutic agents to manage hematologic malignancies. This project is a collaboration between the American Society
GENOM: Myeloma
Dr. Sanjay Juneja (@TheRealOncDoc) and Dr. Ajai Chari (@AjaiChari) discuss the importance of genomic testing and how to understand and interpret test results when treating patients with myeloma. They also discuss the importance of selecting appropriate therapeutic agents to manage hematologic malignancies. This project is a collaboration between the American Society of Hematology and the
GENOM: Lymphoma
Dr. Sanjay Juneja (@TheRealOncDoc) and Dr. David Russler-Germain (@dgermain21) discuss the importance of genomic testing and how to understand and interpret test results when treating patients with lymphoma. They also discuss the importance of selecting appropriate therapeutic agents to manage hematologic malignancies. This project is a collaboration between the American Society of Hemato
GENOM: Chronic Lymphocytic Leukemia
Dr. Sanjay Juneja (@TheRealOncDoc) and Dr. Jacqueline Barrientos discuss the importance of genomic testing and how to understand and interpret test results when treating patients with chronic lymphocytic leukemia (CLL). They also discuss the importance of selecting appropriate therapeutic agents to manage hematologic malignancies. This project is a collaboration between the American Socie
HemeTalks, a podcast featuring conversations in hematology education.
HemeTalks: Conversations in Hematology Education is a brand-new podcast from the American Society of Hematology (ASH)! Listen to educational content from ASH developed by subject-matter experts to meet your professional education needs. Whether you’re a clinician or researcher, ASH has innovative education for every career stage and subspecialty. Season 1, Genomics Essentials in Hematol
