
Intelligent Medicine | The Best of High Tech Medicine and Alternative Modalities
Pioneering complementary medicine practitioner Dr. Ronald Hoffman takes a cutting-edge approach to health, wellness, and aging. He covers both conventional and alternative modalities, as well as nutrition, exercise, and supplements.
Episodes

Beyond Medication: Nutritional Alternatives for Mood Enhancement, Part 1
Nutritional Support for Mood: Magnesium, 5-HTP, Adaptogens, and the Folic Acid Debate: Dr. Ronald Hoffman interviews Neil Levin of NOW Foods/Protocol for Life Balance about rising depression and anxiety and the roles of lifestyle, social media, stress, diet, sleep, and exercise in mood. They discuss nutrient cofactors for neurotransmitter production, emphasizing B vitamins, magnesium, zin

Beyond Medication: Nutritional Alternatives for Mood Enhancement, Part 2
Dr. Hoffman continues his conversation with Neil Levin, Senior Nutrition Education Manager and a product formulator for NOW Foods and Protocol for Life Balance.

Navigating Parenting in the Digital Age: Social Media Risks, Screen Time, and Practical Strategies, Part 1
Dr. Ronald Hoffman interviews pediatrician and public health expert Dr. Megan Moreno, co-author of “Connecting: Raising Kids in the Digital World” and co-medical director of the American Academy of Pediatrics Center of Excellence on Social Media and Youth Mental Health, about how social media and technology affect children’s mental and physical health. They discuss evidence linking tech u

Navigating Parenting in the Digital Age: Social Media Risks, Screen Time, and Practical Strategies, Part 2
Dr. Hoffman continues his conversation with pediatrician and public health expert Dr. Megan Moreno, co-author of “Connecting: Raising Kids in the Digital World” and co-medical director of the American Academy of Pediatrics Center of Excellence on Social Media and Youth Mental Health, about how social media and technology affect children’s mental and physical health.

Intelligent Medicine Radio for October 10, Part 1: Weaponized Plague?
Death at clandestine Siberian bio lab raises specter of weaponized plague leak; Oats for constipation—friend or foe? How long can supplements keep? New weight-loss med that preserves lean body mass nears approval; Reading for pleasure—a waning pastime—enhances memory, mood, and empathy.

Intelligent Medicine Radio for October 10, Part 2: Mistletoe for Cancer?
The brouhaha over fortifying foods with folic acid—is it a cancer promoter? Follow-up to botched Tennessee execution; Whole 30 or Paleo diets for autoimmunity; Mistletoe for cancer; Lifestyle changes may be as effective as cognitive behavioral therapy for depression; Sugar avoidance in first 1000 days of life slows organ aging, reduces later-life disease risk.

Leyla Weighs In: Eating Tips for Exercisers and Energy Drink Warnings
What to Eat After a Fasted Workout—and Why Energy Drinks May Affect Heart Rhythm: Registered dietitian nutritionist Leyla Muedin discusses what to eat after exercise, especially morning fasted workouts, advising water first and avoiding sweet or carb-rich post-workout options (smoothies, bananas, flavored yogurts, cereal, sports drinks) because they can raise blood sugar and insulin, redu

Q&A with Leyla, Part 1: Calcium and Strontium
A discussion on diet and healthFolic acid-fortified foods and cancerHow do I use your store?Why are calcium and strontium often put together in some supplements when they're supposed to be taken apart?

Q&A with Leyla, Part 2: Restless Legs Syndrome
They're back! Fruit and veggie pillsThe benefits of Pycnogenol in lipedemaWhat are some good supplements for my 14- and 18-year-old grandsons?What can I do about my restless legs syndrome?

Preventive Medicine: From Past Discoveries to Future Challenges, Part 1
Preventive Medicine and the “Preventioneers”--From Benjamin Franklin to Modern Public Health: Dr. Ronald Hoffman interviews public health physician Dr. Barry Davis, MD-PhD, author of "The Preventioneers: Diseases, Disasters, and the Discoveries That Changed Our World," about why preventive knowledge often fails to translate into action. Davis explains Benjamin Franklin’s “ounce of prevent

Preventive Medicine: From Past Discoveries to Future Challenges, Part 2
Dr. Hoffman continues his conversation with Barry R. Davis, MD, PHD, Public Health Physician | Biostatistician | Clinical Trials Expert | Professor Emeritus, University of Texas School of Public Health, author of “The Preventioneers: Diseases, Disasters, and the Discoveries That Changed Our World."

The Science and Benefits of Nitric Oxide: The Swiss Army Knife Nutrient for Health, Part 1
Nitric Oxide: Supporting Vascular Health, Performance, and the Oral Microbiome with Dr. Nathan Bryan: Dr. Ronald Hoffman interviews nitric oxide researcher and entrepreneur Dr. Nathan Bryan about nitric oxide (NO) as a short-lived signaling gas that dilates blood vessels, reduces inflammation, mobilizes stem cells, supports mitochondria, and is linked to longevity. Bryan explains two NO p

The Science and Benefits of Nitric Oxide: The Swiss Army Knife Nutrient for Health, Part 2
Dr. Hoffman continues his conversation with nitric oxide researcher and entrepreneur Dr. Nathan Bryan.

Intelligent Medicine Radio for October 3, Part 1: More Powerful Weight Loss Drugs Are On The Launchpad
Ever more powerful weight loss drugs are on the launchpad as FDA issues warnings about bootleg versions—and potential hazards of drastic weight loss to seniors and those with eating disorders; Botched Tennessee execution—how can that happen? Immune support for respiratory syncytial virus (RSV) in a lung cancer survivor; Should beta-glucans be taken with—or away from—food for optimal absor

Intelligent Medicine Radio for October 3, Part 2: The Health Scourge of E-Bikes
Do you have to worry about too much vitamin A from supplements? Urolithin A scores against a common form of heart failure; Most blood tests don’t require fasting; The health scourge of E-bikes; Slashing sugar before antibiotics reduces harms to microbiome; Study shows inadequate REM sleep associated with 83 diseases—but doubts persist over accuracy of sleep wearables.

Leyla Weighs In: Time-Restricted Eating vs. Usual Eating--What Science Says
Time-Restricted Eating Study: Nutritionist Leyla Muedin details a Johns Hopkins Medicine study (published July 27 in Obesity) on time-restricted eating (TRE), a form of intermittent fasting that limits eating to a consistent 8–10 hour daily window, in adults with obesity and prediabetes or diet-controlled type 2 diabetes. In a 12-week trial of mostly female and Black participants, groups

Q&A with Leyla, Part 1: Detoxing Microplastics
The benefits of kimchi for detoxing microplasticsWhat do you recommend my husband take to recover from Bell's Palsy? Follow-up on coronary artery inflammation question

Q&A with Leyla, Part 2: Benefits of Pilates
The benefits of PilatesWhat does it mean that certain brands of nattokinase are "free of K2"?Should I avoid soy products due to my history of breast cancer?How can I choose the best fish oil? Is there a certain dose you recommend?Is there any other supplement I can take besides 5-HTP for mood? What about SAMe?Is there any relief for my friend with ulcerative colitis?

Decoding Omega-3 Benefits: A Discussion with the Godfather of Functional Medicine, Part 1
Fish Oil, Full-Spectrum Omega-3s, and Immunometabolism with Dr. Jeffrey Bland: Dr. Ronald Hoffman interviews Dr. Jeffrey Bland, founder of the Personalized Lifestyle Medicine Institute and Big Bold Health, about fish oil and omega-3 science. Bland recounts becoming involved with commercial fish oil in 1980 while promoting MaxEPA amid the “fat is bad” era and discusses Greenland Inuit rese

Decoding Omega-3 Benefits: A Discussion with the Godfather of Functional Medicine, Part 2
Dr. Hoffman continues his conversation with Dr. Jeffrey Bland, founder of the Personalized Lifestyle Medicine Institute and Big Bold Health, about fish oil and omega-3 science.

How’s Your Cholesterol Level? Why Your LDL Numbers May Not Tell the Whole Story, Part 1
Cholesterol Beyond the Basics: ApoB, Lp(a), Stress, and Aged Garlic Extract for Cardiovascular Risk: Dr. Ronald Hoffman interviews clinical pharmacist and nutritionist Jim LaValle about cardiovascular risk factors beyond total cholesterol, emphasizing that blood tests measure lipoprotein particles and subfractions rather than cholesterol itself. They discuss limitations of relying on surr

How’s Your Cholesterol Level? Why Your LDL Numbers May Not Tell the Whole Story, Part 2
Dr. Hoffman continues his conversation with clinical pharmacist and nutritionist Jim LaValle about cardiovascular risk factors beyond total cholesterol.

Intelligent Medicine Radio for September 26, Part 1: What Super-Agers Over 100 Have in Common
We take the keys away from older drivers—why not older doctors? Nearly 3 in 4 Americans battling this health problem—fatigue! What super-agers over 100 have in common—a hyper-vigilant immune system guarding against cancers and infections. How does “anabolic resistance” contribute to frailty—and what to do about it? Recurrent bouts of “burning sensations” on the face—diagnosis please?

Intelligent Medicine Radio for September 26, Part 2: Dry Fasting
Deadline looms for ban on hemp-derived CBD/THC products—while legal pot proliferates; Scientists disclose IBD benefits of urolithin A; “Dry-fasting” is a new fad—is it healthy? Short “exercise snacks” to break up prolonged inactivity benefit attention and cognition; Kimchi and designer probiotics show promise for flushing out microplastics; LSD soon to be approved as a prescription for an

Leyla Weighs In: The Connection Between Sleep Cycles, Growth Hormone, and Metabolic Health
Sleep, Growth Hormone, and Autophagy: How Rest, Diet, and Fasting Support Metabolic Health and Longevity: Nutritionist Leyla Muedin discusses how deep, early non-REM sleep boosts growth hormone for muscle, bone, fat burning, and metabolic health, and reviews a Cell study in which UC Berkeley researchers mapped hypothalamic circuits and feedback through the locus coeruleus showing a tight

ENCORE: Q&A with Leyla, Part 1: America's Food Fight
America's food fight and dietary guidelinesMy son-in-law suffers from bloating and abdominal pain. Any suggestions?I have positive but low anti-gliadin antibodies. Should I embark on a gluten-free diet?

ENCORE: Q&A with Leyla, Part 2: CoQ10 v. PQQ
I'm a 70-year-old woman with hip arthritis. Any recommendations?A treatment on the horizon for high Lipoprotein (a)?After chemotherapy to help shrink a tumor near my husband's spine, he now has numbness and neuropathy in his legsAnother study implicates meat, and now poultry and fish, in causing cardiovascular diseaseWhat do you think of Consumer Lab's recommendations on supplements?I tak

ENCORE: Beyond Kegels: Comprehensive Pelvic Health with Dr. Sara Reardon, Part 1
Understanding Pelvic Floor Health: Dr. Sarah Reardon, a board-certified pelvic floor physical therapist and author of "FLOORED: A Woman's Guide to Pelvic Floor Health at Every Age and Stage," delves into pelvic floor disorders, highlighting their prevalence, symptoms, and the importance of proper diagnosis and treatment. Dr. Reardon explains the anatomy and function of the pelvic floor, c

ENCORE: Beyond Kegels: Comprehensive Pelvic Health with Dr. Sara Reardon, Part 2
Dr. Hoffman continues his conversation with Dr. Sara Reardon, author of "FLOORED: A Woman's Guide to Pelvic Floor Health at Every Age and Stage."

Culinary Medicine in Focus: Teaching Tomorrow's Doctors Nutrition, Part 1
Teaching Nutrition to Doctors: Dr. Nate Wood, MD, inaugural director of Culinary Medicine at Yale School of Medicine, discusses the persistent lack of nutrition education in medical training. Wood defines culinary medicine as combining nutrition science, medicine, education, and culinary skills to help patients and trainees cook health-promoting food. He reviews diet’s broad impact on chr

Culinary Medicine in Focus: Teaching Tomorrow's Doctors Nutrition, Part 2
Dr. Hoffman continues his conversation with Dr. Nate Wood, MD, inaugural director of Culinary Medicine at Yale School of Medicine.

Intelligent Medicine Radio for September 19, Part 1: Emergency Home Medical Kits
MDs react to JAMA op-ed claiming autonomous AI will outperform doctors on routine medical tasks by 2030, spurring widespread layoffs: When even intravenous iron isn’t enough to stave off anemia; “Emergency “ home medical kits draw ire of medical experts: Meta dinged $567 for teen addiction—why spending it for therapy of adolescents who are hooked on social media may be a waste of money; A

Intelligent Medicine Radio for September 19, Part 2: Bright Lights at Night Emerge as Heart Disease Risk Factor
Cancer rise in younger adults may be explained by accelerated cellular aging; “Quadriceps activation failure” may explain common waking difficulty following successful knee replacement; Is “Calocurb” a good natural alternative to GLP-1 drugs? New study claims 4 to 6 servings of whole grains may be the key to heart health—but doubts arise due to its authorship in Iran, a hotbed of scientif

Leyla Weighs In: The Balance of Cardio and Strength--A Path to Healthy Aging
Concurrent Training for Healthy Aging and the Overlooked B12 Risk of Metformin: Nutritionist Leyla Muedin discusses how concurrent training—combining cardio and strength work—supports healthy aging by building endurance, preserving muscle, and maintaining independence and “healthspan.” She explains that aerobic exercise improves cardiorespiratory efficiency while resistance training prese

Q&A with Leyla, Part 1: AI and The Future of Medicine
Autonomous Artificial Intelligence (AI) and the future of medicineAre there any alternative ways to lower my blood pressure other than taking prescription medication?

Q&A with Leyla, Part 2: The Coronary Artery Inflammation Controversy
As soon as I take my blood pressure meds, I get tired and lack energy for the rest of the day. What gives?I'm 77 and have Sjögren's syndrome. Can I take carnitine? How much should I take?Are there cardiac side effects to berberine? Both my husband and I take it for blood sugar.What types of protein are most helpful for osteoporosis and weight gain?The coronary artery inflammation cont

A Comprehensive Look at Immunity and Supplementation, Part 1
Innate–Adaptive Balance and BWH 85 Beta-Glucan with Functional Medicine Physician Dr. Rob Rountree: He brings a nuanced view of immunity that rejects the simple “immune boosting” dimmer-switch model and emphasizes immune regulation and readiness. He reviews innate immunity as sentinel cells using pattern recognition receptors (e.g., macrophages) and explains how innate and adaptive system

A Comprehensive Look at Immunity and Supplementation, Part 2
Dr. Hoffman continues his conversation with functional medicine practitioner Robert Rountree, MD, medical director of Boulder Wellcare, in Boulder, Colorado, and long-time educator at the Institute for Functional Medicine.

Microbiome Basics: How Pre-, Pro-, and Postbiotics Support Health, Part 1
Dr. Ross Pelton, Director of Science & Education for Essential Formulas Incorporated, maker of Dr. Ohhira’s premium probiotic products, reveals how the gut microbiome affects metabolism, appetite, weight regulation, and overall health. He emphasizes the importance of microbiome diversity, supported by eating a wide variety of plant foods rich in fiber and polyphenols, and discusses ho

Microbiome Basics: How Pre-, Pro-, and Postbiotics Support Health, Part 2
Dr. Hoffman continues his conversation with Dr. Ross Pelton, Director of Science & Education for Essential Formulas Incorporated, maker of Dr. Ohhira’s premium probiotic products.

Intelligent Medicine Radio for September 12, Part 1: Are vegans hotter than meat eaters?
Paying attention to injuries may speed healing—could pain meds blunt the healing response? Fact check: “Everyone over 70 should take a statin”? Billy Joel’s “brain surgery”; How to live past 100—get condemned to “death row”; Are vegans hotter than meat eaters? Promising lp(a) drug fails crucial test; Pain under the left rib cage—what are the possibilities?

Intelligent Medicine Radio for September 12, Part 2: Wobbly Arms and Shaky Legs—could it be FND?
Wobbly arms and shaky legs—could it be FND? Women who start hormones in the 50s have 23% lower dementia risk; How to prep for cataract surgery; Plant-based meat alternatives may deliver harmful mycotoxins; Keto diets outperform low-fat and Mediterranean diets for liver health, blood sugar; NY Times highlights magnesium for sleep; Even a single bout of antibiotics produces long-term harm t

Leyla Weighs In: Oolong Tea, Supplement Absorption, and How Gut Signals Shape Memory
Nutritionist Leyla Muedin answers a listener question about taking many supplements with oolong tea, explaining that tea tannins can interfere with vitamin and mineral absorption; because oolong is partially oxidized, its tannin level falls between green and black tea, so she recommends taking supplements with water and separating them from tea or coffee by at least an hour (ideally 1.5–2

Q&A with Leyla, Part 1: Ultra Processed Food's Impact on Postpartum Depression/Psychosis
Ultra-processed foods' impact on postpartum depression/psychosisWhich should my sister take, Jardiance or Dapagliflozen? I had aortic valve repair. Can I safely take N101?I suffer with trigeminal neuralgia after recent extensive dental work. What do you advise?What would be the optimal total testosterone level for an 84 year old male?

Q&A with Leyla, Part 2: Advice for Lipedema
How can I find an integrative pediatrician in the NYC or Weehawken/Hoboken area?Can the xylitol in my nasal spray have an adverse impact on heart health?I chronically use Vaseline on my lips. Is this a concern?My 25-year-old daughter was diagnosed with lipedema stage one. Any advice?I had an Apo B test and am confused at the results. Could you elucidate?

ENCORE: From Baby Powder to Big Pharma: The Dark Legacy of Johnson & Johnson, Part 1
Former pharma reporter for the New York Times and the Wall Street Journal, investigative reporter Gardiner Harris, discusses his new book “No More Tears: The Dark Secrets of Johnson and Johnson.” It details the unethical practices and numerous scandals that have plagued Johnson & Johnson over the decades, including the asbestos contamination in baby powder, the misuse of the antipsych

ENCORE: From Baby Powder to Big Pharma: The Dark Legacy of Johnson & Johnson, Part 2
Dr. Hoffmabn continues his conversation with investigative reporter Gardiner Harris, author of “No More Tears: The Dark Secrets of Johnson and Johnson.”

Treating Muscle, Inflammatory, Nerve, and Brain Pain with Dr. Jacob Teitelbaum, Part 1
Renowned integrative medicine physician, board-certified internist, and researcher Dr. Jacob Teitelbaum discusses his new book, "Pain Relief in 4 Simple Steps," and the growing chronic pain epidemic (one in four U.S. adults; about 7% debilitating). Teitelbaum argues most pain is treatable by addressing root causes and describes four biochemical pain types—muscle pain from low energy, infl

Treating Muscle, Inflammatory, Nerve, and Brain Pain with Dr. Jacob Teitelbaum, Part 2
Dr. Hoffman continues his conversation with integrative medicine physician, board-certified internist, and researcher Dr. Jacob Teitelbaum about his new book, "Pain Relief in 4 Simple Steps."

Intelligent Medicine Radio for September 5, Part 1: Pros/Cons of CT Scans vs. MRIs
New study attempts to resolve question over which has contributed more to our current obesity epidemic—diet or sedentary lifestyle? Pros/cons of CT scans vs. MRIs for investigating abdominal complaints; Fish oil rivals effectiveness of antibiotics for periodontal disease; The MIND diet vs. KetoFLEX Diet for fending off cognitive decline; Vitamin B3 helps relieve Raynaud’s symptoms; After

Intelligent Medicine Radio for September 5, Part 2: Brain Stimulation with Magnets for Cognitive Impairment?
Scientists reveal how much exercise you really need to protect your heart—and no way are you doing enough! Is that prostate biopsy really necessary? It’s true that statins can reduce heart risk even in 70+ individuals—but they don’t prolong life or fend off disability; Magnesium found to prevent age-related sarcopenia, probably by curbing inflammaging; Deep-brain stimulation with external

Leyla Weighs In: How Rest and Relaxation Revolutionize Health
Exercise, Recovery, Relaxation—and Muscle as the Key to Healthy Aging: Nutritionist Leyla Muedin discusses science-backed wellness trends that pair exercise with effective recovery and deliberate relaxation to support performance, resilience, and healthy aging, noting benefits such as fewer overuse injuries, better sleep, steadier energy, and improved adherence. She highlights relaxation

Q&A with Leyla, Part 1: Burning Mouth Syndrome
Highlights from Dr. Hoffman's vacation.What can my friend take for burning mouth syndrome?I'm looking to build immunity. What are your thoughts on beta-glucans?I hike a lot and want to protect my knees. Would peptides like BPC-157 be of benefit?

Q&A with Leyla, Part 2: Red Meat v. Iron Supplements
How should I take N101 lozenges?Where can I find Propax with NT Factor? I prefer capsule or pill form.Why is the Salad and Salmon diet not mentioned? It's the best of both worlds in a whole-foods eating plan.My doctor wants me to take a statin, but I'm reluctant because of sensitivities and reactions to drugs.I've been told to avoid red meat and instead take an iron supplement, but it's c

ENCORE: Turning Stress into Strength, Part 1
Dr. Sharon Bergquist is an award-winning physician, innovative healthcare leader, and visionary researcher, renowned for spearheading a science-based approach to applying lifestyle as medicine. She is the author of "The Stress Paradox: Why You Need Stress to Live Longer, Healthier, and Happier." She discusses the misunderstood role of stress, emphasizing its potential benefits when manage

ENCORE: Turning Stress into Strength, Part 2
Dr. Hoffman continues his conversation with Dr. Sharon Bergquist, author of "The Stress Paradox: Why You Need Stress to Live Longer, Healthier, and Happier."

ENCORE: Vitamin D: How Rickets Shaped Nutritional Science, Part 1
The Long Shadow of Rickets: Vitamin D, Historical Insights, and Modern Implications. Dr. Chris Warren, a history professor at Brooklyn College delves into the origins and prevalence of rickets, a condition now largely unknown but once widespread. Dr. Warren explains the factors contributing to rickets, particularly Vitamin D deficiency, and shares insights from his book, "Starved for Ligh

ENCORE: Vitamin D: How Rickets Shaped Nutritional Science, Part 2
Dr. Hoffman continues his conversation with Dr. Chris Warren, author of "Starved for Light: The Long Shadow of Rickets and Vitamin D Deficiency."

ENCORE: Intelligent Medicine Radio for August 29, Part 1: Persistent Itch
Dr. Marty Makary out as FDA Commissioner—was he the victim of a BigPharma purge? Are “liquid biopsies” useful for predicting recurrences, as well as guiding therapy, for cancer? Nighttime smartphone by adolescents surges, eroding kids’ sleep needs; Persistent itch may require an “all of the above” approach to break its vicious cycle—could topical vitamin B12 provide an answer? Study criti

ENCORE: Intelligent Medicine Radio for August 29, Part 2: Menopausal Sleep Problems
You won’t believe this new medical use for Classic Coca-Cola; The solution for menopausal sleep problems goes beyond mere hormone replacement; Paxlovid strikes out vs. Covid in new trials; Pesticide exposure may explain rising colorectal cancer rates in young people; Big Food touts faulty study that claims healthier food regulations will cost consumers; Higher aerobic fitness boosts size

Leyla Weighs In: From Prescription to Plate--Embracing Food as Clinical Care
Food as Medicine: Why Medical Nutrition Therapy and Medically Tailored Meals Belong in Modern Healthcare: Registered dietitian nutritionist Leyla Muedin argues that food should be treated with the same rigor as medication through medical nutrition therapy (MNT) and “diet prescriptions,” integrating nutrition into treatment plans rather than leaving it as optional advice. She cites evidenc

ENCORE: Q&A with Leyla, Part 1: Genetic Testing
The 23 & Me bankruptcyThe promise of genetic testing in the futureWhat are your thoughts on methylene blue? Any benefits?

ENCORE: Q&A with Leyla, Part 2: Deep, Restful Sleep
How can I treat polycythemia caused by erythropoietin receptor mutation?I have chronic anemia—not iron deficiency. What can I do for my foggy head?What do you recommend for vestibular migraine?Any natural treatments for deep, restful sleep?SLIT - Sublingual Immunotherapy treatment

ENCORE: Cognitive Wellness: Strategies to Preserve and Enhance Brain Function, Part 1
Understanding and Preserving Cognitive Health with Dr. Barbara Haskin: In this episode of the Intelligent Medicine podcast, host Dr. Ronald Hoffman discusses cognitive health with neuropsychologist Dr. Barbara Haskin, author of “How My Brain Works: A Guide to Understanding It Better and To Keeping It Healthy.” They explore the impact of aging and other factors on cognitive function, citin

ENCORE: Cognitive Wellness: Strategies to Preserve and Enhance Brain Function, Part 2
Dr. Hoffman continues his conversation with Dr. Barbara Haskin, author of “How My Brain Works: A Guide to Understanding It Better and To Keeping It Healthy.”

ENCORE: Biohacking Your Genes: Navigating the Genetic Path to Wellness, Part 1
In this episode of the Intelligent Medicine Podcast, Dr. Ronald Hoffman interviews Dr. Sharad Paul, a New Zealand physician, on his book, "Biohacking Your Genes: 25 Laws for a Smarter, Healthier, and Longer Life." They discuss how genes serve as a blueprint but not a destiny, stressing the role of lifestyle and habits in managing genetic risks. Dr. Paul expands on the impact of diet, supp

ENCORE: Biohacking Your Genes: Navigating the Genetic Path to Wellness, Part 2
Dr. Hoffman continues his conversation with Dr. Sharad Paul, author of "Biohacking Your Genes: 25 Laws for a Smarter, Healthier, and Longer Life."

ENCORE: Intelligent Medicine Radio for August 22, Part 1: Does drinking carbonated water help weight loss?
New-think on diet for ApoE4, a risk factor for Alzheimer’s—eat meat! Is a non-invasive blood sugar monitor on the drawing board for the next Apple Watch? True or false—does drinking carbonated water help weight loss? Eating while distracted puts on the pounds; Treating duodenitis; How much whey protein should you consume? Why some people fail to lose weight on GLP-1 drugs.

ENCORE: Intelligent Medicine Radio for August 22, Part 2: New Hope Against Pancreatic Cancer
Don’t skip homocysteine when testing for dementia risk factors; Treating osteoporosis; New hope against pancreatic cancer; Eating right for Parkinson’s Disease; Olive oil helps stave off dementia—but only the right kind; A lifestyle hack that can cut Alzheimer’s risk by 38%; How to reduce high calprotectin on a stool test.

Leyla Weighs In: Morning Coffee and Supplements--What Not to Mix
Supplements and Morning Coffee: Timing Iron, Zinc, Calcium, B Vitamins, and Vitamin D: Nutritionist Leyla Muedin explains that coffee (and tea) can interfere with nutrient absorption and digestion, so certain supplements shouldn’t be taken with morning coffee. Coffee’s tannins and polyphenols can significantly reduce non-heme iron absorption (decaf doesn’t prevent this), and similar bindi

ENCORE: Q&A with Leyla, Part 1: At Home Prostate Tests
An example of another bad 'scientific' studyWhat do you think of the new at-home prostate test?My calcium score has increased over the years. Am I taking enough Vitamin K? Too much?

ENCORE: Q&A with Leyla, Part 2: Heating Pad for Pain
A case study in high cholesterolHow can I lower my Apolipoprotein B? My husband's A1c went up after taking a statin for 5 months. Help!Can you recommend a good foot cream?Using a heating pad for pain — a listener's success storyHow long of a break should I take from my supplement regimen?

Your Ultimate Guide to Magnesium: Facts, Benefits, and Solutions, Part 1
Natalie Ochoa, president of Jigsaw Health, details widespread magnesium insufficiency and why it occurs (soil depletion, low plant intake/processed foods, stress-related loss, aging, and medication effects including diuretics and proton pump inhibitors). They discuss the poor reliability of standard serum magnesium testing, the limitations of RBC magnesium testing, and using symptoms such

Your Ultimate Guide to Magnesium: Facts, Benefits, and Solutions, Part 2
Dr. Hoffman continues his conversation with Natalie Ochoa, president of Jigsaw Health.

Caffeinated Insights: New Findings in Heart Health, Part 1
Cardiologist and electrophysiologist Dr. Gregory Marcus, chair of the American Heart Association scientific statement writing group, reveals evidence on coffee/caffeine and cardiovascular health. He discusses how earlier assumptions that caffeine triggers arrhythmias are complicated by genetics, individual risk factors, and mostly observational research. Marcus reviews randomized and obse

Caffeinated Insights: New Findings in Heart Health, Part 2
Dr. Hoffman continues his conversation with cardiologist and electrophysiologist Dr. Gregory Marcus, chair of the American Heart Association scientific statement writing group.

Intelligent Medicine Radio for August 15, Part 1: Avocado Oil
Most mayos, salad dressings and chips “made with 100% avocado oil” fail test; Borderline cholesterol—will a coronary calcium scan help decide whether a statin is warranted? Aged Garlic Extract for blood pressure; Immune benefits of BWH Beta Glucan.

Intelligent Medicine Radio for August 15, Part 2: That Fishy Smell
Low-fat dairy shown to confer no weight, cholesterol benefits over full-fat dairy; FDA and USDA to define ultra-processed foods for first time—but what are they really? Newly discovered tick-borne Bourbon virus can be fatal—but is it more pervasive than we think? Thorne supplement maker—sold 3 years ago for $700 million—acquired by Procter & Gamble for $3.8 billion. Those dark skin bl

Leyla Weighs In: Genetic Mutations and Health Impacts
Managing High Homocysteine with MTHFR Variants and the Role of Vitamin C in Brain Aging: Registered dietitian nutritionist Leyla Muedin discusses MTHFR genetic variants (C677T and A1298C), their links to impaired methylation, homocysteine, SAMe, mood issues, migraines, vitamin deficiencies, and pregnancy complications, noting many people are asymptomatic and some feel worse on methylated

Q&A with Leyla, Part 1: The New Vaccine Schedule Recommendations
The new vaccine schedule recommendationsMy urologist is giving me grief that my vitamin D level is too highWhich nattokinase do you recommend to treat long covid?Is the vitamin K in your bone protocol different from the heart protocol?What about methylated B vitamins for brain vs. heart health?
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