
Intelligent Medicine | The Best of High Tech Medicine and Alternative Modalities
Pioneering complementary medicine practitioner Dr. Ronald Hoffman takes a cutting-edge approach to health, wellness, and aging. He covers both conventional and alternative modalities, as well as nutrition, exercise, and supplements.
Episodes

Leyla Weighs In: Morning Coffee and Supplements--What Not to Mix
Supplements and Morning Coffee: Timing Iron, Zinc, Calcium, B Vitamins, and Vitamin D: Nutritionist Leyla Muedin explains that coffee (and tea) can interfere with nutrient absorption and digestion, so certain supplements shouldn’t be taken with morning coffee. Coffee’s tannins and polyphenols can significantly reduce non-heme iron absorption (decaf doesn’t prevent this), and similar bindi

ENCORE: Q&A with Leyla, Part 1: At Home Prostate Tests
An example of another bad 'scientific' studyWhat do you think of the new at-home prostate test?My calcium score has increased over the years. Am I taking enough Vitamin K? Too much?

ENCORE: Q&A with Leyla, Part 2: Heating Pad for Pain
A case study in high cholesterolHow can I lower my Apolipoprotein B? My husband's A1c went up after taking a statin for 5 months. Help!Can you recommend a good foot cream?Using a heating pad for pain — a listener's success storyHow long of a break should I take from my supplement regimen?

Your Ultimate Guide to Magnesium: Facts, Benefits, and Solutions, Part 1
Natalie Ochoa, president of Jigsaw Health, details widespread magnesium insufficiency and why it occurs (soil depletion, low plant intake/processed foods, stress-related loss, aging, and medication effects including diuretics and proton pump inhibitors). They discuss the poor reliability of standard serum magnesium testing, the limitations of RBC magnesium testing, and using symptoms such

Your Ultimate Guide to Magnesium: Facts, Benefits, and Solutions, Part 2
Dr. Hoffman continues his conversation with Natalie Ochoa, president of Jigsaw Health.

Caffeinated Insights: New Findings in Heart Health, Part 1
Cardiologist and electrophysiologist Dr. Gregory Marcus, chair of the American Heart Association scientific statement writing group, reveals evidence on coffee/caffeine and cardiovascular health. He discusses how earlier assumptions that caffeine triggers arrhythmias are complicated by genetics, individual risk factors, and mostly observational research. Marcus reviews randomized and obse

Caffeinated Insights: New Findings in Heart Health, Part 2
Dr. Hoffman continues his conversation with cardiologist and electrophysiologist Dr. Gregory Marcus, chair of the American Heart Association scientific statement writing group.

Intelligent Medicine Radio for August 15, Part 1: Avocado Oil
Most mayos, salad dressings and chips “made with 100% avocado oil” fail test; Borderline cholesterol—will a coronary calcium scan help decide whether a statin is warranted? Aged Garlic Extract for blood pressure; Immune benefits of BWH Beta Glucan.

Intelligent Medicine Radio for August 15, Part 2: That Fishy Smell
Low-fat dairy shown to confer no weight, cholesterol benefits over full-fat dairy; FDA and USDA to define ultra-processed foods for first time—but what are they really? Newly discovered tick-borne Bourbon virus can be fatal—but is it more pervasive than we think? Thorne supplement maker—sold 3 years ago for $700 million—acquired by Procter & Gamble for $3.8 billion. Those dark skin bl

Leyla Weighs In: Genetic Mutations and Health Impacts
Managing High Homocysteine with MTHFR Variants and the Role of Vitamin C in Brain Aging: Registered dietitian nutritionist Leyla Muedin discusses MTHFR genetic variants (C677T and A1298C), their links to impaired methylation, homocysteine, SAMe, mood issues, migraines, vitamin deficiencies, and pregnancy complications, noting many people are asymptomatic and some feel worse on methylated

Q&A with Leyla, Part 1: The New Vaccine Schedule Recommendations
The new vaccine schedule recommendationsMy urologist is giving me grief that my vitamin D level is too highWhich nattokinase do you recommend to treat long covid?Is the vitamin K in your bone protocol different from the heart protocol?What about methylated B vitamins for brain vs. heart health?

Q&A with Leyla, Part 2: Is taking Bergamot for cholesterol really effective?
What are your thoughts on Cleveland Clinic's assessment of fish oil supplements?If I want to go on your sleep protocol, should I order all of the supplements or choose one?Do you still recommend individual assessments to determine natural treatments for anxiety and depression?Is taking Bergamot for cholesterol really effective?

Mold Exposure Uncovered: Health Implications and New Approaches, Part 1
Chemical engineer and MoldCo founder Ariana Thacker discusses mold-related illness, including chronic inflammatory response syndrome (CIRS), as a major blind spot in conventional care for chronic, multi-system symptoms. Thacker recounts developing rapid-onset brain fog, slurred speech, GI issues, hair loss, weight gain, and shortness of breath after six and a half months in a moldy Miami

Mold Exposure Uncovered: Health Implications and New Approaches, Part 2
Dr. Hoffman continues his conversation with chemical engineer and MoldCo founder Ariana Thacker.

Clear Air, Clean Water: Helen Christoni on Reducing Household Pollutants, Part 1
Creating a Healthier Home: Indoor Air Purification and Reverse Osmosis Water Safety. Environmental and wellness expert Helen Christoni discusses reducing toxic exposures at home through improved indoor air and water quality. Christoni describes her health crisis—severe osteoporosis at 42 and multiple fractures—which she attributes to chronic artificial fragrance exposure in beauty product

Clear Air, Clean Water: Helen Christoni on Reducing Household Pollutants, Part 2
Dr. Hoffman continues his conversation with environmental and wellness expert Helen Christoni.

Intelligent Medicine for August 8, Part 1: The Pros and Cons of Male Circumcision
What happened to all those Balance of Nature commercials we used to hear? What are the pros and cons of male circumcision? Do women wearing thongs get more vaginal infections? Controversy over statins for seniors; An avocado a day may keep the cardiologist away; Major study flags frailty risks with GLP-1 drugs for seniors; Unlicensed doctor arrested after patient dies following NAD+ infus

Intelligent Medicine for August 8, Part 2: Your Future Drug Deliveries May Be Via Drones
High-dose Vitamin D fails test in treatment of advanced colon cancer—but can prevent many early cancers from metastasizing; IV Vitamin C may delay progression Myelodysplastic syndrome, pancreatic cancer; Your future drug deliveries may be via drones; How to fight age-related “anabolic resistance”; Can osteoporosis be reversed with hormone replacement therapy and resistance exercise?

Leyla Weighs In: Effective Strategies for Blood Sugar Control
Lowering A1C in Prediabetes and Using Less Insulin on a Low-Carb Diet: Leyla Muedin, a registered dietitian nutritionist, answers listener questions about blood sugar and insulin. Responding to Rita, whose hemoglobin A1C rose from 5.6 to 5.8, Layla says “glucose hacks” to blunt carb absorption aren’t appropriate at that level and recommends a strict very low-carb/keto approach (under 25 g

Q&A with Leyla, Part 1: Protein Intake Across the Lifespan
Could you please comment on the new study that finds protein restriction could slow aging?Considerations for protein intake across the lifespanMy bone mineral density has improved with strontium. Should I stop taking it? What about vitamin K2?

Q&A with Leyla, Part 2: Pros and Cons of Gallbladder Removal
My HgbA1c is steady at 5.5. Could I reduce my metformin dose against the advice of my endocrinologist who states it's good for longevity?I have a large gallstone and am wondering what the pros and cons of having my gallbladder removed are.I take a lot of vitamins and am wondering if there's any easier way to ingest them?

ENCORE: Medical Errors and Patient Advocacy: Dr. Julie's Guide to Hospital Stays, Part 1
Dr. Julie Siemers, a nurse educator and author of “Surviving Your Hospital Stay: A Nurse Educator's Guide to Staying Safe and Living to Tell About It,” details the importance of patient safety in hospitals, the dangers of medical errors, and how patients and their families can advocate for better care. Dr. Siemers talks about the critical role of nurses, the hierarchy within the nursing p

ENCORE: Medical Errors and Patient Advocacy: Dr. Julie's Guide to Hospital Stays, Part 2
Dr. Hoffman continues his conversation with Dr. Julie Siemers, a nurse educator and author of “Surviving Your Hospital Stay: A Nurse Educator's Guide to Staying Safe and Living to Tell About It.”

Exploring Hormonal Health: From Testosterone to the Secrets of Longevity, Part 1
Precision Hormone Health: Testosterone, Menopause, Muscle, Sleep, and Proactive Longevity: Endocrinologist Dr. Florence Comite details her book “Invincible: Defy Your Genetic Destiny to Live Better, Longer” and her precision-medicine approach to proactive longevity. She discusses testosterone decline beginning in the 30s in both sexes, stress-related low T (including in special forces), a

Exploring Hormonal Health: From Testosterone to the Secrets of Longevity, Part 2
Dr. Hoffman continues his conversation with endocrinologist Dr. Florence Comite.

Intelligent Medicine Radio for August 1, Part 1: Watching Too Much TV May Shrink Your Brain (Literally!)
Life is longer for “those who think young”; Watching too much TV may shrink your brain (literally!); Diet and supplements may help lupus; When a high-fiber diet before surgery may be inadvisable; Your mouth may be the gateway to your overall health and longevity.

Intelligent Medicine Radio for August 1, Part 2: A novel treatment for knee pain—fiber!
Advantages of time-restricted eating for body and brain; Dermatologist tells her patient to stay away from hair supplements; Do you still need colonoscopies past 75? How much NTFactor should you take? Breathing CO2 clears brain of amyloid plaque; Popular AI diet tracking apps may underestimate by as much as 345 calories; A novel treatment for knee pain—fiber! Vitamin D slows biological ag

Leyla Weighs In: Holistic Healing--Integrating Mind, Body, and Spirit
Leyla Muedin, a registered dietitian nutritionist in New York City, discusses the growing shift from symptom-only “sick care” to a clinically grounded holistic approach to health and recovery. She argues that self-guided wellness routines can leave gaps when underlying medical issues, mental health conditions, substance use disorders, or trauma remain unaddressed, and emphasizes integrati

Q&A with Leyla, Part 1: Varicose Veins
Is there evidence for statins in the treatment of aortic valve stenosis?How the bacteria behind gum disease can affect heart healthWouldn't it be better to resume taking probiotics after finishing a round of antibiotics?Would it be safe to take olive leaf extract with amoxicillin?I'm considering surgery for varicose veins. Is this just a temporary fix? Can they return?

Q&A with Leyla, Part 2: Is chondroitin effective?
My 25-year-old son has bipolar disorder and can't tolerate his medications. Any natural recommendations?Is chondroitin effective? It's in my collagen capsules, which I take to hopefully reduce wrinklesI believe I am still suffering from the negative effects of COVID. What would you suggest I take?

Integrative Naturopathic Gastroenterology: Fecal Transplants, Diet, Probiotics, and Helminth Therapy, Part 1
Naturopathic gastroenterologist Mark Davis, ND (FABNG), discusses his work in fecal microbiota transplantation (FMT), research, and integrative approaches to GI disease. Davis explains FMT history, screening criteria, delivery methods, how it differs from probiotics, and why it is highly effective for recurrent C. difficile (about a 90% durable cure), while noting FDA-approved products (R

Integrative Naturopathic Gastroenterology: Fecal Transplants, Diet, Probiotics, and Helminth Therapy, Part 2
Dr. Hoffman continues is conversation with naturopathic gastroenterologist Mark Davis, ND (FABNG).

Breaking New Ground: Psychedelics in Modern Psychiatry, Part 1
Psychedelic Therapy for Mental Health: Research, Safety, and the Path to FDA Approval: Dr. Will Van Derveer and Keith Kurlander, co-authors of “Psychedelic Therapy: A Revolutionary Approach to Restoring Your Mental Health and Reclaiming Your Life,” reveal the shift from recreational psychedelics to structured, research-based psychedelic-assisted therapy for conditions like PTSD, depressio

Breaking New Ground: Psychedelics in Modern Psychiatry, Part 2
Dr. Hoffman continues his conversation with Dr. Will Van Derveer and Keith Kurlander, co-authors of “Psychedelic Therapy: A Revolutionary Approach to Restoring Your Mental Health and Reclaiming Your Life.”

Intelligent Medicine Radio for July 25, Part 1: Breakthroughs in Gene Editing Promise to Vanquish Aging
Science is conquering diseases—now breakthroughs in gene editing promise to vanquish aging itself; The healing potential of hydrogen; Attending concerts, museums and movies may help keep your body younger; Dr. Jeffrey Bland dishes on the benefits of a new full-spectrum fish oil, Omega-3 Rejuvenate.

Intelligent Medicine Radio for July 25, Part 2: American Heart Association Does a 180° on Coffee
This week’s supplement spotlight—spermidine; American Heart Association does a 180° on coffee; How accurate are health tracker wearables for sleep, blood pressure, heart rate? A skin disorder practically no one has heard of is often confused for skin cancer; Vitamin D—what forms and what dosages are optimal? Popular sugar substitutes may be worse for the brain than natural sugar.

Leyla Weighs In: Suppressing Belly Fat
What Triggers Age-Related Belly Fat? New Stem Cell Findings and a Nutrition Perspective: Nutritionist Leyla Muedin discusses research from City of Hope (published in Science) on why belly fat increases with age even without major weight gain, emphasizing the health risks of visceral fat as an endocrine organ linked to inflammation, diabetes, heart disease, and accelerated aging. The study

Q&A with Leyla, Part 1: Nature or Nurture
Nature or nurture—which is more important when it comes to health conditions?Would I benefit from taking nattokinase along with my statin?Mechanism of action of nattokinase vs. statin medications on coronary artery health

Q&A with Leyla, Part 2: Lithium Orotate for Therapeutic Benefit
My LDL is 421, and I have mild to moderate aortic stenosis. Must I take a statin?Lean Mass Hyper-responders on low carb diets explainedWould you consider writing a book about health in advancing age?A revisit of Dr. Hoffman's published booksWhat is the best dose of lithium orotate for therapeutic benefit?Must I exercise fasted? Why?

Beyond the Mind: The Interplay of Mental and Physical Health, Part 1
The Brain–Body Connection, Gut Health, Stress, and Medical Gaslighting: board-certified psychiatrist Dr. Susan Trachman, author of “It’s Not Just In Your Head,” about psychosomatic medicine and the two-way brain–body connection. Trachman explains how patients with complex symptoms are often dismissed as having “medically unexplained symptoms” and discusses medical gaslighting, especially

Beyond the Mind: The Interplay of Mental and Physical Health, Part 2
Dr. Hoffman continues his conversation with board-certified psychiatrist Dr. Susan Trachman, author of “It’s Not Just In Your Head.”

Infections and the Mind: A New Perspective on Alzheimer's, Part 1
Can Infections Drive Alzheimer’s? Nikki Schultek, founder of Intracel Research Group and co-founder of the Alzheimer’s Pathobiome Initiative, details evidence that pathogens may contribute to Alzheimer’s and other neurodegenerative and neuroimmune disorders beyond the amyloid hypothesis. Schultek recounts her own misdiagnosed systemic illness with neurodegenerative symptoms, later found t

Infections and the Mind: A New Perspective on Alzheimer's, Part 2
Dr. Hoffman continues his conversation with Nikki Schultek, founder of Intracel Research Group and co-founder of the Alzheimer’s Pathobiome Initiative.

Intelligent Medicine Radio for July 18, Part 1: Preserving Brain Function
Diets rich in fruits and vegetables preserve brain function—but in vulnerable persons with the ApoE4 “Alzheimer’s gene”, more meat staves off decline, contradicting years of recommendations to minimize animal protein; Supplements for adrenal insufficiency; “Forever chemicals” may weaken teen’s bones—but menopausal hormone replacement therapy decisively fends off osteoporosis; Legionnaire'

Intelligent Medicine Radio for July 18, Part 2: Testosterone Screening for Troops
Pentagon plans widespread testosterone screening for troops; New study claims arthroscopic surgery for age-related degenerative changes of knees is worthless; Widely touted “precision” proton therapy doesn’t outperform conventional radiation treatment for prostate cancer; Comparing the effectiveness of gummies and liquids vs. tablet or capsule forms of supplements; Supplements to lower LD

Leyla Weighs In: The Hidden Impact of B12 Deficiency on Aging
Vitamin B12 Deficiency--The “Aging” Symptoms You Shouldn’t Ignore: Leyla Muedin, a registered dietitian nutritionist in New York City, discusses vitamin B12 deficiency as a common problem that can mimic normal aging, noting adults need only about two micrograms daily to support red blood cells, nerves, and DNA. She reviews the history of liver treatment for pernicious anemia and explains

Q&A with Leyla, Part 1: Aortic Dissection
Does coffee really dehydrate you? A deeper dive on this important topicHelp for nighttime urinationPlease discuss aortic dissection

Q&A with Leyla, Part 2: Mushroom Coffee
How do I find a preventive cardiologist in northern New Jersey?What is the best supplement for dissolving bone spurs?What is the half-life of vitamin D, either by supplement or sun exposure?What do you think about mushroom coffee? Does it have any health benefits?Please discuss how strontium affects DEXA scan results

Vagus Nerve Stimulation for Rheumatoid Arthritis and Beyond, Part 1
Dr. David Chernoff, Chief Medical Officer of Setpoint Medical, discusses electrically driven vagus nerve stimulation (VNS) as a “neuroimmune modulation” approach to autoimmune and inflammatory disease. Chernoff explains the vagus nerve’s sensory role in monitoring organs and signaling the brainstem and spleen to regulate immune responses, and how precise stimulation can reduce pro-inflamm

Vagus Nerve Stimulation for Rheumatoid Arthritis and Beyond, Part 2
Dr. Hoffman continues his conversation with Dr. David Chernoff, Chief Medical Officer of Setpoint Medical.

Unlocking the Power of Nutraceutical Mushrooms, Part 1
Mushrooms for Sleep and Cognitive Support: Jim LaValle, a clinical pharmacist, author, and board-certified clinical nutritionist, details Wakunaga/Kyolic’s new Specialty Series mushroom products and related health strategies. He reveals a sleep formula with reishi, L-theanine, valerian, and Aged Garlic Extract aimed at calming stress and supporting better sleep. The formula for cognition

Unlocking the Power of Nutraceutical Mushrooms, Part 2
Dr. Hoffman continues his conversation Jim LaValle, a clinical pharmacist, author, and board-certified clinical nutritionist.

Intelligent Medicine Radio Show for July 11, Part 1: Internal Visceral Fat May Accelerate Brain Aging
Carnitine, with acknowledged muscle and brain benefits, may find a new role in supporting cancer immunity; Calcium and vitamin D’s bone-building impact may be limited; Internal visceral fat may accelerate brain aging, MRI study finds; The remarkable benefits of a newly-discovered mitochondrial booster—urolithin A (Mitopure®️).

Intelligent Medicine Radio for July 11, Part 2: Is it safe to stop statins “cold turkey”?
Is it safe to stop statins “cold turkey”? Can the supplement ingredient HMB counteract age-related muscle loss? Researchers may have discovered the key to development of a true fat-burning weight loss medication; Can a mammogram yield clues about cardiovascular risk? Their bottom line threatened by GLP-1 weight loss drugs, BIg Food tweaks portion sizes, adds spices and flavorings to pique

Leyla Weighs In: Do Probiotics Hold the Key to Detoxifying Heavy Metals?
Registered dietitian Leyla Muedin discusses a Frontiers in Microbiology paper suggesting certain probiotics may help sequester heavy metals. The study, sponsored by the Italian company Probiotical and conducted with University of Ghent and University of Piedmont Orientale, researchers used in vitro testing and the SHIME gut simulator to assess Lactiplantibacillus plantarum, Lactobacillus

Q&A with Leyla, Part 1: Dealing With The Heat
Dealing with the heat - Europeans' disdain for air conditioningI have scaly and bumpy areas on my scalp that itch!Did homeopathic human growth hormone increase my cholesterol?

Q&A with Leyla, Part 2: Is there any remedy for frequent nighttime urination?
Which is more effective, vitamin K2 or K4?How long can I take L-tryptophan as a sleep aid? What about 5-HTP?Is there any remedy for frequent nighttime urination?What are some suitable supplements I can take for exercise recovery?

The Science of Immune Regulation and Resilience, Part 1
Immune Regulation, Omega-3 Nuance, and Himalayan Tartary Buckwheat with Dr. Austin Perlmutter, chief science officer of Big Bold Health. He details immune regulation as a nuanced, multidimensional system shaped by diet and lifestyle rather than simple “boosting.” Perlmutter explains Big Bold Health’s focus on immunometabolism, educating about immune complexity, and conducting studies on n

The Science of Immune Regulation and Resilience, Part 2
Dr. Hoffman continues his conversation with Dr. Austin Perlmutter, chief science officer of Big Bold Health.

Breaking Ground in Biotech: The Role of AI and Gene Editing, Part 1
AI and Generative Biology: Authoring Life, Redesigning Healthcare, and Building Guardrails: Physician and molecular biologist Dr. Adrian Woolfson, co-founder of Genyro, a biotechnology company specializing in synthetic genome design and construction, and author of “On the Future of Species: Authoring Life by Means of Artificial Biological Intelligence,” discusses the convergence of AI wit

Breaking Ground in Biotech: The Role of AI and Gene Editing, Part 2
Dr. Hoffman continues his conversation with physician and molecular biologist Dr. Adrian Woolfson, co-founder of Genyro, a biotechnology company specializing in synthetic genome design and construction, and author of “On the Future of Species: Authoring Life by Means of Artificial Biological Intelligence.”

Intelligent Medicine Radio for July 4, Part 1: Break a Sweat to Beat the Heat
Europeans swelter through historic heat wave—but many resist air conditioning due to ingrained cultural attitudes; Break a sweat to beat the heat; Evidence that aged garlic extract curbs atherosclerosis risk; How to stave off age-related muscle atrophy; Probiotic-infused underwear to nourish the skin microbiome? Niacin augments glioblastoma treatment; Creatine for depression.

Intelligent Medicine Radio for July 4, Part 2: Causes of Excessive Sleepiness
Melatonin can reduce chronic pain; Ultra-processed foods are becoming a worldwide scourge; Do biopsies spread cancer? Sauna benefits for staving off dementia; What may cause blood sugars to deteriorate in a heretofore well-controlled diabetic? Causes of excessive sleepiness.

Leyla Weighs In: Beyond Calcium--Unraveling Nutritional Insights for Bone Strength
Bone Health Beyond Calcium: Vitamin D, K, Protein, Medications, and Metabolic Risks: Registered dietitian nutritionist Leyla Muedin discusses factors affecting bone health, osteopenia/osteoporosis, and limitations of bone mineral density as a measure of bone strength. She emphasizes optimizing vitamin D via 25-hydroxy D testing (aiming roughly 55–85 and avoiding over 100), ensuring vitami

Q&A with Leyla, Part 1: Carnivore Diet Controversies
Carnivore diet controversiesWhat is a normal oxygen saturation? Mine has been 92-93 lately? Is that okay?

Q&A with Leyla, Part 2: Oral vs. IV Chelation
I've worked for many years on my feet and had surgery on both knees. How much glucosamine should I take?Can you discuss oral vs. IV chelation? How do you determine which is appropriate?How important is nitric oxide, and how can I increase mine?Are there any supplements I should stop taking before getting blood tests?

Heart Matters: Essential Supplements for Cardiovascular Protection, Part 1
Cardiovascular Protection Beyond Statins--Nattokinase, Vitamin K2 MK-7, and Clinical Cardio Six: Neil Levin of NOW Foods/Protocol for Life Balance details cardiovascular protection beyond cholesterol-lowering drugs, emphasizing nutrient sufficiency, therapeutic “nutraceutical” dosing, and physician partnership with testing. They discuss nattokinase from fermented natto (typical 2,000 fibr

Heart Matters: Essential Supplements for Cardiovascular Protection, Part 2
Dr. Hoffman continues his conversation with Neil Levin, the Senior Nutrition Education Manager and a product formulator for NOW(r) Foods and Protocol for Life Balance.

Urolithin A: A Pathway to Enhanced Energy and Longevity, Part 1
Urolithin A (Mitopure) and Mitochondrial Renewal--Muscle, Immune, and Skin Benefits: Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline details urolithin A and Timeline’s branded supplement Mitopure. She describes urolithin A’s discovery through pomegranate research and worm studies showing a 45% lifespan increase. She discusses human research including improved w

Urolithin A: A Pathway to Enhanced Energy and Longevity, Part 2
Dr. Hoffman continues his conversation with Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline.

Intelligent Medicine Radio for June 27, Part 1: 80+ “Supermovers”
“The quick and the dead”: 80+ “Supermovers” show slowed cognitive decline; Dietary polyphenols help overcome vascular effects of prolonged sitting; Pros and cons of ketamine therapy for depression; Time-restricted eating alters microbiome to promote weight loss; Magnesium—what research reveals about better sleep, stress resilience, and whole-body wellness.

Intelligent Medicine Radio for June 27, Part 2: CBD May Slow Alzheimer’s Progression
CBD may slow Alzheimer’s progression by tamping down brain inflammation; Fifty million dollar settlement in Gardasil Classic action; Urethral stricture as a side effect of ablation for enlarged prostate; Zero-sugar diet may have unanticipated adverse health consequences; Are there drug-free alternatives for atrial fibrillation? Can you reverse lactose intolerance with a skin patch?

Leyla Weighs In: Vitamin K2--The Heart’s Unsung Hero
Vitamin K2 (MK-7) and Coronary Artery Calcification: Insights from a 2-Year Trial: Nutritionist Leyla Muedin discusses a two-year randomized clinical trial in JAMA Cardiology from Maastricht University Medical Center reporting that daily vitamin K2 (menaquinone-7, MK-7) at 360 mcg slowed progression of coronary artery calcification (CAC) in 180 patients with confirmed atherosclerotic card

Q&A with Leyla, Part 1: Sarcoidosis of the Lung
World Cup!What did humans eat from the Ice Age to the Bronze Age?What supplements should I avoid while undergoing radiation therapy for prostate cancer?What is the treatment for sarcoidosis of the lung? Both my friend and his wife have it.

Q&A with Leyla, Part 2: Vibration devices to help osteoporosis?
I'm 78 and had a hysterectomy. Is it safe for me to eat tofu or other soy foods?Mitopure joins L'Oreal to create a face cream with Urolithin A.Does taking hyaluronic acid orally cause water retention?Can you discuss ETA contained in New Zealand green mussels?What are your thoughts on using vibration devices to help osteoporosis?

Xylitol for Oral and Nasal Microbiome Support + Allergy Relief, Part 1
Nathan Jones, founder and CEO of Xlear, Inc., reveals xylitol’s role in supporting oral and nasal “gateway” microbiomes by selectively starving acid-producing Strep mutans rather than indiscriminately killing bacteria, and warns that harsh mouthwashes can disrupt beneficial oral bacteria linked to nitric oxide production and possibly blood pressure. Jones outlines Spry and Xlear products

Xylitol for Oral and Nasal Microbiome Support + Allergy Relief, Part 2
Dr. Hoffman continues his conversation with Nathan Jones, founder and CEO of Xlear, Inc.

The Key to Cardiovascular Health and Longevity: Exploring Nitric Oxide, Part 1
Nitric Oxide Explained: Vascular Health, Exercise Performance, and N1o1 with Dr. Nathan Bryan, international Leader in Molecular Medicine, the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health. He details NO as a ubiquitous messenger affecting blood flow, erectile function, cognition, exercise performance, endothelial dysfunction,

The Key to Cardiovascular Health and Longevity: Exploring Nitric Oxide, Part 2
Dr. Hoffman continues his conversation with Dr. Nathan Bryan, international Leader in Molecular Medicine, the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health.

Intelligent Medicine Radio for June 20, Part 1: Undereye “Festoons”
Should you stop taking glucosamine based on a new study linking it to Alzheimer’s? What’s behind the spate of “Tai Chi Walking” social media posts? Undereye “festoons”—what to do about them? Are antibiotics the only treatment for SIBO? Vaping after smoking hikes risk for lung cancer.
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