Home Podcasts Distillations | Science History Institute
Distillations | Science History Institute

Distillations | Science History Institute

Science History Institute 365 Episodes Jun 30, 2026

Distillations is the Science History Institute's critically acclaimed flagship podcast. It takes deep dives into stories that range from the serious to the eccentric, helping listeners better understand the surprising science that is all around us. Episodes cover topics from the crisis in Alzheimer's research to New England's 19th-century vampire panic in compelling, sometimes-funny, documentary-style audio stories.

Episodes

The History of Clinical Trials: From Fake Exorcisms to Testing Today
The History of Clinical Trials: From Fake Exorcisms to Testing Today Jun 30, 2026 54:19 Alexis Pedrick joins Sam Jones and Deboki Chakravarti to bring you an episode from Tiny Matters, an award-winning podcast from the American Chemical Society produced by Multitude. The episode, which originally aired in February 2026, explores the surprising origins and evolution of one of modern medicine's most important tools: the clinical trial. Tiny Matters follows the development of experime
Agnes Pockels and the Kitchen Sink Myth
Agnes Pockels and the Kitchen Sink Myth Mar 19, 2026 37:28 This episode is a co-production with Lost Women of Science. Agnes Pockels did pioneering work in surface science. Her invention, the Pockels Trough, became the basis for an instrument that helped Katherine Burr Blodgett and Irving Langmuir make discoveries in material science that quietly shape our everyday world.  But the way we talk about Agnes's life and work often falls back on familiar tr
Flemmie Kittrell and the Preschool Experiment
Flemmie Kittrell and the Preschool Experiment Sep 30, 2025 52:04 Alexis Pedrick joins Katie Hafner to bring you an episode from The Lost Women of Science Initiative, a non-profit educational organization dedicated to telling the forgotten or untold stories of remarkable female scientists and their groundbreaking work through history.  The episode, which originally aired in October 2023, is about Flemmie Kittrell, the first Black woman to earn a PhD in Home Ec
The CRISPR Babies
The CRISPR Babies Sep 11, 2025 53:33 In 2018 news broke that a Chinese scientist, He Jiankui, had used CRISPR to edit human embryos, and twin girls had been born as a result. The story set off an explosive bioethical controversy. As gene editing expert Kiran Musunuru put it, "He Jiankui's genetic misadventures were the biggest medical story of the century so far." Both scientists and the public had a lot of questions. What was the u
Humans and Monsters: An Interview with Surekha Davies
Humans and Monsters: An Interview with Surekha Davies Sep 9, 2025 31:38 The fears about genetic engineering were stoked when experiments took off in the 1970s. From lab leaks to disease epidemics to the ability to make "Frankenstein creations," many of those fears are still with us today. We talk to author Surekha Davies about her latest book, why she thinks of monsters as category breakers and why blurring boundaries can be so terrifying for us, but maybe doesn't hav
IVF: An Interview with Robin Marantz
IVF: An Interview with Robin Marantz Sep 2, 2025 43:49 Our producer Rigoberto Hernandez spoke with Robin Marantz, the author of Pandora's Baby: How the First Test Tube Babies Sparked the Reproductive Revolution. She tells us about the history of IVF, from the first known artificial insemination by donor produced in Philadelphia in the 19th century to the scientific race in the 1960s and 1970s that resulted in the first so-called "test-tube baby." Cred
Gene Therapy's Families
Gene Therapy's Families Aug 26, 2025 42:45 When Rebekah and Evan Lockard's daughter, Naomi, was diagnosed with a devastating ultra-rare genetic disease, they didn't know where to turn. Then they found Terry Pirovolakis, an IT professional who had made a gene therapy for his son with the same disease. But the process of getting Naomi treated has been an uphill battle, full of financial and logistical obstacles. The Lockard's story flips the
Gene Therapy's Dark Ages
Gene Therapy's Dark Ages Aug 19, 2025 49:02 Gene therapy is based on a simple-sounding, yet deceptively complicated premise: adding or replacing faulty genes to fix medical problems. A compelling idea that came out of breakthroughs in DNA research, the field grew lightning fast. But the death of teenager Jesse Gelsinger after a gene therapy clinical trial left the public and scientists questioning the field's promise.  Why did researchers p
'The Andromeda Strain': An Interview with Luis Campos
'The Andromeda Strain': An Interview with Luis Campos Aug 12, 2025 39:31 Producer Mariel Carr talks to historian of science and former Science History Institute fellow, Luis Campos, about his article "Strains of Andromeda: The Cosmic Potential Hazards of Genetic Engineering." He shares how Michael Crichton's first novel and the subsequent film influenced the conversation and controversy around recombinant DNA research in the 1970s. Credits Host: Alexis Pedrick Executiv
The People vs. Recombinant DNA
The People vs. Recombinant DNA Aug 5, 2025 44:33 In 1976, Harvard University wanted to build a specialized lab for recombinant DNA research. But first, it had to get permission from the city of Cambridge. The resulting city council hearings drew TV stations and captured the attention of the whole country. At the center of the controversy? A wise-talking mayor, a young outspoken molecular biologist, and an important question: in scientific resear
Science, Interrupted: Part 2
Science, Interrupted: Part 2 Jul 30, 2025 44:24 Genetic engineering breakthroughs in the late 1960s and early 1970s came with a lot of promise—and peril too. Fears about what could happen with recombinant DNA experiments put scientists in the middle of a moral dilemma. Did they have a responsibility to consider how  others might use their work? Or was their place simply to be on the lab bench? In this two-part episode, we'll share the story abo
Science, Interrupted: Part 1
Science, Interrupted: Part 1 Jul 30, 2025 41:55 Genetic engineering breakthroughs in the late 1960s and early 1970s came with a lot of promise—and peril too. Fears about what could happen with recombinant DNA experiments put scientists in the middle of a moral dilemma. Did they have a responsibility to consider how  others might use their work? Or was their place simply to be on the lab bench? In this two-part episode, we'll share the story abo

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