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Manifold

Steve Hsu 168 Episodes Aug 13, 2026

Steve Hsu, a professor of theoretical physics at Michigan State University, hosts wide-ranging conversations with leading writers, scientists, technologists, academics, entrepreneurs, and investors. The podcast explores topics at the intersection of science, technology, and society, blending rigorous thinking with accessible discussion. Each episode features in-depth interviews that cover everything from fundamental physics to the latest trends in business and innovation.

Episodes

Venture Capital and Technology in China with Bohan Lou – #118
Venture Capital and Technology in China with Bohan Lou – #118 Aug 13, 2026 3946 Bohan Lou is a partner at Chemistry Ventures, based in SF.https://x.com/loubohanBohan's report on the venture ecosystem in China:https://www.linkedin.com/posts/bohanlou_i-spent-last-month-in-china-meeting-most-ugcPost-7487909585689698304-qepw/Chapter Markers:(01:42) - Venture Capital in China; Bohan’s Shanghai Roots (11:15) - Chemistry Fund and China Investing (20:04) - China Trip and Ven
Iran, AI, and the Third World War (Crossover with Seeking Truth From Facts Podcast) – #117
Iran, AI, and the Third World War (Crossover with Seeking Truth From Facts Podcast) – #117 Jul 30, 2026 3164 This is a crossover episode with Alf Beckinsale, an Oxford University student who hosts the Seeking Truth From Facts podcast. The main topics are the US-Iran conflict, geopolitics, and US-China AI competition.Chapter Markers:(00:00) - Introduction (02:33) - No Off Ramp in Gulf (04:11) - Missile Stockpile Crisis (06:46) - Oil Shock and Reserves (14:07) - Israel Stays Out (29:34) - China Fr
State of AI, Summer 2026 – #116
State of AI, Summer 2026 – #116 Jul 16, 2026 3093 Steve discusses the state of AI in summer 2026. Topics covered include: AI in math and theoretical physics, Recursive Self-Improvement, Agent swarms and tokenomics, IPOs and US-China competition, documentary film Machine God.Machine God trailer: https://www.youtube.com/watch?v=5RSv3wmDIpYTheoretical Physics with Generative AI: https://stevehsu.substack.com/p/theoretical-physics-with-gener
Beff Jezos and Effective Accelerationism: Machine God of Loving Grace – #115
Beff Jezos and Effective Accelerationism: Machine God of Loving Grace – #115 Jul 2, 2026 6057 Beff Jezos (Guillaume Verdon) is a Canadian physicist, quantum computing researcher, and tech entrepreneur. He is best known as the founder of the Effective Accelerationism (e/acc) movement.This interview was recorded in collaboration with John Greer and Lei Huang for the documentary film Machine God.John Greer: https://www.johncgreer.com/Chapter Markers:(00:00) - Meet Beff Jezos (01:56)
Razib Khan at Manifest 2026: Genetic Discoveries, AI, and Academia – #114
Razib Khan at Manifest 2026: Genetic Discoveries, AI, and Academia – #114 Jun 18, 2026 4832 This episode was recorded live at Manifest 2026. Razib Khan is a prominent writer, population geneticist, and podcaster. He is best known for his extensive deep-dives into human evolutionary history, consumer genomics, culture, and ancient DNA. https://x.com/razibkhanhttps://x.com/razibkhan?lang=enChapter Markers:(00:00) - Razib Khan at Manifest 2026: Genetic Discoveries, AI, and Academia
Letter from Beijing 2: Tsinghua University – #113
Letter from Beijing 2: Tsinghua University – #113 Jun 4, 2026 4868 This special episode was recorded at Tsinghua University in Beijing, generally regarded as the top university in China. Our guests are 3 Americans studying and working at Tsinghua: Gabriel (undergrad), Justin (PhD student in AI), and Alex (Professor in AI research). Topics discussed include: Tsinghua University and elite human capital, AI in China, US-China competition, and the flow of hu
AI Billionaire on Existential Risk: Jaan Tallinn – #112
AI Billionaire on Existential Risk: Jaan Tallinn – #112 May 21, 2026 6041 Jaan Tallinn is a tech billionaire and founding engineer of Skype who leverages his wealth to mitigate existential risks from artificial general intelligence (AGI). He co-founded the Future of Life Institute and the Centre for the Study of Existential Risk, while making early foundational investments in frontier AI labs like DeepMind andAnthropic.Chapter Markers:00:00 Assessing Current AI
Embryo Selection and Frontier Genomics with Dr. Alex Young – #111
Embryo Selection and Frontier Genomics with Dr. Alex Young – #111 May 7, 2026 5458 Dr. Alex Young, a statistical geneticist and assistant professor in the Human Genetics department at UCLA, joins Steve Hsu to discuss the cutting edge of genomic prediction. They cover his research on polygenic embryo screening in IVF (including the ImputePGTA method), family-based DNA analysis, missing heritability, and the implications of polygenic scores for traits like education and d
Iran War is the First Missile War (crossover with Seeking Truth From Facts podcast) – #110
Iran War is the First Missile War (crossover with Seeking Truth From Facts podcast) – #110 Apr 23, 2026 2967 Steve and Alf discuss the Iran War, emphasizing what itreveals about modern missile and anti-missile technology, drones, andthe implications for a US-China conflict in the Western Pacific.Links:https://seekingtruthfromfacts.substack.com/Chapter Markers:(00:00) - Missile War Reality Check (01:49) - How the War Started (04:46) - Iran Outperforms Expectations (06:22) - Why Missile Defense Fa
Dreamers and Doomers: Our AI future, with Richard Ngo – #109
Dreamers and Doomers: Our AI future, with Richard Ngo – #109 Apr 9, 2026 6691 Richard Ngo is an independent AI researcher and philosopher known forhis work on AGI safety and alignment. He recently resigned fromOpenAI, where he was a member of the Governance team focused onforecasting the capabilities and risks of advanced AI systems. Hisdebut fiction collection is titled "The Gentle Romance: Stories of AIand Humanity", published in December 2025. The book features
China, Acceleration, and Nick Land - with Matt Southey – #108
China, Acceleration, and Nick Land - with Matt Southey – #108 Mar 26, 2026 3818 Matt Southey is an editor for an AI safety organization. He wrote his PhD dissertation on the philosophy of Nick Land. Matt's "A Brief History of Accelerationism" can be found here, and he recommends the second chapter of Crypto-Current as a good introduction to Land's usage of Kant. He and Steve discuss Accelerationism, AI, and Steve's recent meeting with Land in Shanghai.Chapter Markers
Shenzhen is the Technology Capital of the World, with Taylor Ogan – #107
Shenzhen is the Technology Capital of the World, with Taylor Ogan – #107 Mar 12, 2026 4281 Recorded live in Shenzhen with Taylor Ogan, the founder and CEO ofSnowbull Capital, which invests in Chinese technology companies.Taylor on X:https://x.com/TaylorOganPrevious episodes with Taylor:https://youtu.be/iehHON07UHI?si=h2c3po5AX9Z9ANaK https://youtu.be/fmjR3me5s_Q?si=sPsMFOdKebEOZXQr(00:00) - Shenzhen is the Technology Capital of the World, with Taylor Ogan (00:53) - Meeting in S

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