Home Podcasts Manifold
Manifold

Manifold

Steve Hsu 168 Episodes Oct 8, 2026

Steve Hsu, a professor of theoretical physics at Michigan State University, hosts wide-ranging conversations with leading writers, scientists, technologists, academics, entrepreneurs, and investors. The podcast explores topics at the intersection of science, technology, and society, blending rigorous thinking with accessible discussion. Each episode features in-depth interviews that cover everything from fundamental physics to the latest trends in business and innovation.

Episodes

AI Boom or Bust? – #122
AI Boom or Bust? – #122 Oct 8, 2026 2371 Are we in an AI bubble? Steve reviews analysis on CapEx, AI revenues, OAI+ANT burn rates. AI revenue has to reach $trillions per annum within the next few years (an increase of > 10x; compare total global software revenue of $1.5T today), or else the current CapEx spend will turn out to be a huge misallocation. Separately, even if total AI revenue reaches these levels, OAI and ANT coul
Effort News and AI-Driven Journalism with Brian Chau – #121
Effort News and AI-Driven Journalism with Brian Chau – #121 Sep 24, 2026 4265 Brian Chau is a mathematician, machine learning specialist, and the founder of Effort News, an independent media outlet focused on data-first, document-led investigative journalism.https://www.effort.news/https://x.com/brianchau57Chapter Markers:(00:00) - Intro (03:14) - Network School Fallout (14:17) - Effort News Origins (17:24) - AI Reporting Workflow (35:41) - Medicare Medicaid Moment
Machine God: Hsu, Greer, Huang – #120
Machine God: Hsu, Greer, Huang – #120 Sep 10, 2026 4474 Machine God is a feature-length AI documentary film, created by Steve Hsu, John Greer, and Lei Huang. This episode discusses the film's creation and content.Chapter Markers:(00:00) - Meet the Filmmakers (02:06) - Berkeley AI Boomtown Origins (19:23) - Techno Capital and the Pause Plea (38:55) - Why Slow Down AI (41:40) - Recursive Self Improvement (46:01) - Gradual Disempowerment (51:48)
How to Build a Research Institute: Thomas Fink of the London Institute for Mathematical Sciences – #119
How to Build a Research Institute: Thomas Fink of the London Institute for Mathematical Sciences – #119 Aug 27, 2026 3633 Dr. Thomas Fink is an Anglo-American physicist, author, and entrepreneur who serves as the founding Director of the London Institute for Mathematical Sciences (LIMS).He studied physics at Caltech, where he won the Fisher Prize, and earned his PhD at Cambridge University. His research focuses on statistical physics, combinatorics, and evolvable systems, using these tools to gain insights i
Venture Capital and Technology in China with Bohan Lou – #118
Venture Capital and Technology in China with Bohan Lou – #118 Aug 13, 2026 3946 Bohan Lou is a partner at Chemistry Ventures, based in SF.https://x.com/loubohanBohan's report on the venture ecosystem in China:https://x.com/loubohan/status/2082143914924851449Chapter Markers:(01:42) - Venture Capital in China; Bohan’s Shanghai Roots (11:15) - Chemistry Fund and China Investing (20:04) - China Trip and Venture Reality Check (32:18) - Pressure Cooker: Founder Exits and F
Iran, AI, and the Third World War (Crossover with Seeking Truth From Facts Podcast) – #117
Iran, AI, and the Third World War (Crossover with Seeking Truth From Facts Podcast) – #117 Jul 30, 2026 3164 This is a crossover episode with Alf Beckinsale, an Oxford University student who hosts the Seeking Truth From Facts podcast. The main topics are the US-Iran conflict, geopolitics, and US-China AI competition.Chapter Markers:(00:00) - Introduction (02:33) - No Off Ramp in Gulf (04:11) - Missile Stockpile Crisis (06:46) - Oil Shock and Reserves (14:07) - Israel Stays Out (29:34) - China Fr
State of AI, Summer 2026 – #116
State of AI, Summer 2026 – #116 Jul 16, 2026 3093 Steve discusses the state of AI in summer 2026. Topics covered include: AI in math and theoretical physics, Recursive Self-Improvement, Agent swarms and tokenomics, IPOs and US-China competition, documentary film Machine God.Machine God trailer: https://www.youtube.com/watch?v=5RSv3wmDIpYTheoretical Physics with Generative AI: https://stevehsu.substack.com/p/theoretical-physics-with-gener
Beff Jezos and Effective Accelerationism: Machine God of Loving Grace – #115
Beff Jezos and Effective Accelerationism: Machine God of Loving Grace – #115 Jul 2, 2026 6057 Beff Jezos (Guillaume Verdon) is a Canadian physicist, quantum computing researcher, and tech entrepreneur. He is best known as the founder of the Effective Accelerationism (e/acc) movement.This interview was recorded in collaboration with John Greer and Lei Huang for the documentary film Machine God.John Greer: https://www.johncgreer.com/Chapter Markers:(00:00) - Meet Beff Jezos (01:56)
Razib Khan at Manifest 2026: Genetic Discoveries, AI, and Academia – #114
Razib Khan at Manifest 2026: Genetic Discoveries, AI, and Academia – #114 Jun 18, 2026 4832 This episode was recorded live at Manifest 2026. Razib Khan is a prominent writer, population geneticist, and podcaster. He is best known for his extensive deep-dives into human evolutionary history, consumer genomics, culture, and ancient DNA. https://x.com/razibkhanhttps://x.com/razibkhan?lang=enChapter Markers:(00:00) - Razib Khan at Manifest 2026: Genetic Discoveries, AI, and Academia
Letter from Beijing 2: Tsinghua University – #113
Letter from Beijing 2: Tsinghua University – #113 Jun 4, 2026 4868 This special episode was recorded at Tsinghua University in Beijing, generally regarded as the top university in China. Our guests are 3 Americans studying and working at Tsinghua: Gabriel (undergrad), Justin (PhD student in AI), and Alex (Professor in AI research). Topics discussed include: Tsinghua University and elite human capital, AI in China, US-China competition, and the flow of hu
AI Billionaire on Existential Risk: Jaan Tallinn – #112
AI Billionaire on Existential Risk: Jaan Tallinn – #112 May 21, 2026 6041 Jaan Tallinn is a tech billionaire and founding engineer of Skype who leverages his wealth to mitigate existential risks from artificial general intelligence (AGI). He co-founded the Future of Life Institute and the Centre for the Study of Existential Risk, while making early foundational investments in frontier AI labs like DeepMind andAnthropic.Chapter Markers:00:00 Assessing Current AI
Embryo Selection and Frontier Genomics with Dr. Alex Young – #111
Embryo Selection and Frontier Genomics with Dr. Alex Young – #111 May 7, 2026 5458 Dr. Alex Young, a statistical geneticist and assistant professor in the Human Genetics department at UCLA, joins Steve Hsu to discuss the cutting edge of genomic prediction. They cover his research on polygenic embryo screening in IVF (including the ImputePGTA method), family-based DNA analysis, missing heritability, and the implications of polygenic scores for traits like education and d

Recommended