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Paper Podcast

Paper Podcast

Paper Podcast 37 Episodes Sep 27, 2026

This podcast features interviews with scientists about their favorite research papers. The show aims to give research a direct and honest voice by having scientists discuss the work they find most compelling. Each episode highlights a specific paper through the eyes of an expert. The tone is informal and enthusiastic, designed to make academic research accessible and personal.

Episodes

Episode 39: Reinhard Genzel (Nobel Prize in Physics): Radiointerferometry, large telescopes, and measuring the universe
Episode 39: Reinhard Genzel (Nobel Prize in Physics): Radiointerferometry, large telescopes, and measuring the universe Sep 27, 2026 00:29:47 (German episode) In this second part with Reinhard Genzel (Nobel Prize winner in Physics 2020), the central topics are astronomy method engineering and physics. Reinhard Genzel explains about radiointerferometry, quantum noise, and the largest telescopes on Earth with bendable mirror optics. How to reach 10,000x in sensitivity in science? On the side, we discuss funding and team leadership for suc
Episode 38: Reinhard Genzel (Nobel Prize in Physics): Measuring molecules, the universe, and our place in this world
Episode 38: Reinhard Genzel (Nobel Prize in Physics): Measuring molecules, the universe, and our place in this world Sep 12, 2026 00:25:50 (German episode) Reinhard Genzel won the Nobel Prize in 2020 for the discovery of Sagittarius A*, the black hole in the center of our galaxy. Reinhard shares a story of becoming scientist and his work Charles Towns, the godfather of lasers and masers. The first laser is now still exhibited at the Max Planck Institutes in Garching (by Munich, Germany). Reinhard is one group leader there and uses in
Episode 37: Mario R. Capecchi (Nobel Prize in Medicine and Physiology): The first knockout-mice and anxiety in pigs
Episode 37: Mario R. Capecchi (Nobel Prize in Medicine and Physiology): The first knockout-mice and anxiety in pigs Sep 5, 2026 00:16:10 Mario R. Capecchi won the Nobel Prize in 2007 for his work on the first knockout mice. Today, we widely take knockout mice and his methods for gene targeting for granted. They have become the standard for functional genetics and preclinical assessments. In this episode, Mario shares his view on giving the brain something to do. We talk about his early work on protein translation of viruses, about
Episode 36: Klaus Blaum & Erproben einer fünften Kraft mit feinen Kernmessungen
Episode 36: Klaus Blaum & Erproben einer fünften Kraft mit feinen Kernmessungen Aug 23, 2026 00:12:00 Klaus Blaum ist Direktor am Max-Planck-Institut für Kernphysik in Heidelberg. Seine Arbeitsgruppe hält Rekorde in den präzisesten Messungen von Kernmassen und der Elektronenmasse. In dieser Episode stellt uns Klaus zwei Publikationen vor, welche die Grenzen des Standardmodells austesten. Kombiniert man präzise bekannte Isotopenmassen mit genau gemessenen Frequenzverschiebungen eines bestimmten ele
Episode 35: Samuele Piccinelli & Quantum computing for a molecule with half-Möbius topology
Episode 35: Samuele Piccinelli & Quantum computing for a molecule with half-Möbius topology Jun 14, 2026 00:15:14 Today, we talk about the algorithm and quantum chemical calculations behind the molecule with half-Möbius topology as Part 2 (for Part 1, see last episode). Samuele Piccinelli - PhD student at EPFL and IBM Zurich - discusses with us his path into physics and his intuition on quantum algorithmic design. He introduced SqDRIFT, the algorithm used to probe the unique electronic structure of the half-M
Episode 34: Igor Rončević & A molecule with half-Möbius topology
Episode 34: Igor Rončević & A molecule with half-Möbius topology May 31, 2026 00:29:18 Recently, a molecule with new electronic structure was constructed, atom-by-atom using atomic force methodology. Igor Rončević is the first author behind this recent Science paper and shares with us how the molecule's electronic properties can be understood, what Möbius and half-Möbius topology mean, why the molecule bends, and how he can actually flip between topologies of the molecule. It is
Episode 33: Stephen Giovannoni & Cheeto-shaped and ubiquitous proteobacteria
Episode 33: Stephen Giovannoni & Cheeto-shaped and ubiquitous proteobacteria May 17, 2026 00:12:14 Do we know what is in the ocean? In 2002, Stephen Giovannoni with his team discovered and cultured an extremely abundant and small proteobacterium, Candidatus pelagibacter, and with this we knew: We previously did not know about a quarter of the plankton in our oceans. Candidatus pelagibacter constitutes 25% of the global plankton population, is cheeto-shaped, and is hunted by an army of specializ
Episode 32 (70th Birthday): Bill DeGrado & Protein Design
Episode 32 (70th Birthday): Bill DeGrado & Protein Design Apr 5, 2026 00:10:19 This episode was recorded on 12th Sept. 2025. This marks Bill DeGrado's 70th birthday. Many thanks for what you did from the whole field! :)Bill DeGrado is one of the early protein designers who defined the field and coined the terms. His papers describe the first de novo designs, starting from helices to ion channels to catalytic centers. This episode is a kind mix of experiences shared as ch
Episode 31: Rolf Thauer & Nickel-Enzyme in Methan-bildenden Mikroorganismen
Episode 31: Rolf Thauer & Nickel-Enzyme in Methan-bildenden Mikroorganismen Mar 8, 2026 00:24:29 Rolf Thauer ist Gründungsdirektor des Max-Planck Instituts für terrestrische Mikrobiologie. Über seine Karriere klärte er zahlreiche Stoffwechselwege in anaeroben Bakterien und Archaeen (die damals noch nicht einmal so hießen) auf. Er erzählt uns über die Zufallsentdeckung das Feld der Nickelbiochemie, und Enzymen für Methanproduktion aus Wasserstoff. Dieses können wir dann in die normalen Erdgasp
Episode 30: Birte Höcker & Computergestütztes Proteindesign
Episode 30: Birte Höcker & Computergestütztes Proteindesign Feb 22, 2026 00:10:03 Birte Höcker forscht daran, neue Enzyme herzustellen. Dabei kombiniert sie das Feld der Biochemie mit den computergestützten Informationswissenschaften. Anhand einer ihrer Lieblingsreaktionen, der Triosephosphate Isomerase Reaktion (TIM), zeigt Birte uns, wie man zwei verschiedene Computermodell verwenden und verglichen kann, um solche Enzyme neu zu designen und loss-of-function Bakterienstämme da
Episode 29: Renko de Vries & Ice-binding proteins
Episode 29: Renko de Vries & Ice-binding proteins Jan 25, 2026 00:10:41 Some organisms survive cold temperatures and need protection against ice crystals in their bloodstream. Renko de Vries and his students embarked on a journey to elucidate such mechanisms and design novel antifreeze proteins. How can a biological protein recognize an inorganic ice surface? Why are threonines important, and what has the winter flounder to do with it? A podcast on the fascination for
Episode 28: Jordi Bella & The collagen triple helix
Episode 28: Jordi Bella & The collagen triple helix Jan 18, 2026 00:12:51 Jordi Bella was the first scientist to look at the structure of collagen, an amazing triple helix that creates our cartilage, intervertebral disks, and other connective tissues. A special amino acid, hydroxyproline, is part of the story, together with different collagen application types to talk about. Where does our collagen come from, and can tobacco plants produce it?Link to the paper: ⁠https:/

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