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Serious Inquiries Only

Serious Inquiries Only

seriouspod.com 844 Episodes Oct 7, 2026

Serious Inquiries Only is a podcast hosted by Thomas that explores science, philosophy, skepticism, and politics. It features thoughtful conversations with guests, blending critical thinking with humor. Rather than a typical interview show, it aims for engaging, friendly dialogue on serious topics. The tone is entertaining and accessible without being boring.

Episodes

SIO531: Your Brain Is Actually Two Separate Organs, According to a New Stanford Study
SIO531: Your Brain Is Actually Two Separate Organs, According to a New Stanford Study Oct 7, 2026 56:47 We welcome back Dr. Eric Jaffe to help us understand a really cool, groundbreaking scientific discovery! Our brains are not one organ! Turns out your forebrain and your hindbrain might be two completely separate lineages that never actually came from each other, more like two kids in a trench coat than one continuous evolution. Why does that matter for ALS research? And how far back in evolution d
SIO530: Did AI Actually "Solve" That Famous Math Problem?
SIO530: Did AI Actually "Solve" That Famous Math Problem? Oct 1, 2026 51:16 You've seen the headline: AI "solved" one of math's Millennium Prize problems. Thomas and Jenessa (here as a friend, not an expert) are joined by David Souther, a software engineer and LLM researcher, who's SO annoyed about it. Why did he answer Jenessa's text in all caps? And what's the deal with a rushed phone call between OpenAI and a math professor? Are you an expert in something and want to b
SIO529: AI in Schools Makes Students Feel Smarter. The Tests Say Otherwise.
SIO529: AI in Schools Makes Students Feel Smarter. The Tests Say Otherwise. Sep 30, 2026 01:03:08 How does AI use affect learning? You'd be surprised how much we already know. Dr. Jenessa Seymour takes us through the research on screen use, metacognition, cognitive offloading, and some recent papers Sources: Clinton, V. (2019). Reading from paper compared to screens: A systematic review and meta-analysis. Journal of Research in Reading, 42, 288-325. Deslauriers, L., McCarty, L.S., Miller, K.
SIO528: The Marshmallow Test Is Mostly BS, and It's Not the Only Classic Psych Test Like That
SIO528: The Marshmallow Test Is Mostly BS, and It's Not the Only Classic Psych Test Like That Sep 29, 2026 50:56 Kids are weird, like really weird, but in a fun way? Dr. Jenessa Seymour is back to tell us about some classic child development paradigms that really need to be reevaluated. Depending on when you learned about these experiments, you were either taught that they were the gospel truth, with established ages where kids can and cannot pass these tests, and major consequences for late development, or
SIO527: The Science of Why We Ask Why, with Dr. Tania Lombrozo
SIO527: The Science of Why We Ask Why, with Dr. Tania Lombrozo Sep 15, 2026 48:45 Dr. Tania Lombrozo, professor of psychology at Princeton University (affiliated with its philosophy and cognitive science departments), joins Thomas to discuss her forthcoming book Why We Ask Why: The Science of Explanation and the Human Drive to Understand. Why are humans so driven to explain things, but only some things? Why does understanding go beyond just being able to predict? And what happe
SIO526: Why Is College So Expensive?
SIO526: Why Is College So Expensive? Sep 1, 2026 54:13 David O'Brien, higher education policy scholar with the California Community Colleges System, is back to answer the question Thomas posed last time: why is college so expensive? They get into tuition vs. total cost of attendance, the dirty little secret of private university pricing, administrative bloat, the amenities arms race, and why the people loudest about college costs are likely well-off,
Some More News Is COMPLETELY WRONG About Spider-Man Brand New Day
Some More News Is COMPLETELY WRONG About Spider-Man Brand New Day Aug 31, 2026 01:38:07 I cannot stop thinking about Cody from Some More News's video in which he could not stop thinking about Spider-Man: Brand New Day. Cody is INCREDIBLY sure that you're an idiot incapable of watching movies or consuming art if you don't agree with his conception of what the ending of Brand New Day meant. The problem is... Cody gets about a billion things wrong and his arguments are terrible. This w
SIO525: Dude Who Said Autism Is "Extreme Male Brain" Walks It Back
SIO525: Dude Who Said Autism Is "Extreme Male Brain" Walks It Back Aug 11, 2026 59:04 ... and other autism/ADHD research! So pleased to have Dr. Jenessa Seymour back - this time with a variety of studies in the Autism and ADHD realms. Jurek, L., Duchier, A., Gauld, C., Henault, L., Giroudon, C., Fourneret, P., … Nourredine, M. (2025). Sensory processing in individuals with Attention-Deficit/Hyperactivity Disorder compared with control populations: A systematic review and meta-ana
SIO524: Why We Haven't Cured Cancer Yet, Part 2 (with Dr. Eric Jaffe)
SIO524: Why We Haven't Cured Cancer Yet, Part 2 (with Dr. Eric Jaffe) Jul 29, 2026 47:58 Part 2! Dr. Eric Jaffe returns to actually treat the cancer this time: why radiation is basically catching your kid smoking and making him finish the carton, how CRISPR turns your own T cells into an assassin squad, and why oncolytic viruses are just Jurassic World Dominion for tumors. Haven't heard Part 1 yet? Start there or you'll be lost. Mentioned: CAR-T therapy RAS inhibitor drugs Oncol
SIO523: What Cancer Actually Is, Part 1 (with Dr. Eric Jaffe)
SIO523: What Cancer Actually Is, Part 1 (with Dr. Eric Jaffe) Jul 28, 2026 56:05 Part 1! Dr. Eric Jaffe, the biology teacher who keeps naming proteins after cartoon characters, returns for a two-part cancer deep dive. Today: what cancer actually is at the cellular level, why elephants barely get it, why whales get it even less, and why the "they're hiding the cure" conspiracy falls apart the second you learn who actually funds the research. Mentioned: Peto's paradox HeLa c
SIO522: College Is Impossibly Expensive. But It's Not Because of Bogus Degrees.
SIO522: College Is Impossibly Expensive. But It's Not Because of Bogus Degrees. Jul 21, 2026 40:56 Part 2! Thomas is joined again by David O'Brien, a higher education policy scholar with the California Community Colleges system, to finish dismantling The Daily's take on Trump's student loan crackdown. Reagan, Pell Grants, and decades of quiet state defunding all get their due, plus a theory on why tuition keeps climbing that has nothing to do with cosmetology degrees. Mentioned: The Daily col
SIO521: The Daily Is Sane-Washing Trump's War on Higher Ed
SIO521: The Daily Is Sane-Washing Trump's War on Higher Ed Jul 21, 2026 47:25 Thomas is joined by David O'Brien, a higher education policy scholar who works for the California Community Colleges system, to pick apart Trump's new rules threatening to cut off student loans and Pell grants from "low-earning" degree programs, and to fact-check The Daily's recent take on the same story. The real history runs through Reagan, Prop 13, and decades of quiet austerity nobody on that

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