
Analytically Speaking
Analytically Speaking is the podcast from LCGC and Spectroscopy magazines, covering separation science and analytical spectroscopy. Episodes address new analytical techniques, methods and trends, along with advances in instrument and software technology and practical solutions for specific applications. The show also examines recent papers in the scientific literature and their applicability, as well as challenges in data analysis and interpretation, plus analytical chemistry theory and fundamentals. It is hosted by Dwight Stoll, PhD, a chemistry professor at Gustavus Adolphus College who covers separation science, and Jerry Workman, PhD, a spectroscopist and Senior Technical Editor of Spectroscopy and LCGC who handles spectroscopy topics.
Episodes

Ep. 48: From Fortran to Field Flow Fractionation
Welcome to “Analytically Speaking,” the podcast from LCGC International and Spectroscopy.
In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Mark Schure, who has worked in separation science for over 35 years in both industry and academia. Over a 28-year period, he worked for Digital Equipment Corporation, the Rohm and Haas Company, and the Dow Chemical Company.

Ep 47: The Other Half of Beer’s Law
Welcome to “Analytically Speaking,” the podcast from LCGC International and Spectroscopy.
Here in Episode #47, podcast host Dr. Jerry Workman speaks with Dr. Thomas Mayerhöfer from the Leibniz Institute of Photonic Technology (Leibniz IPHT) in Jena, Germany, and Friedrich Schiller University Jena, about “the other half” of the Beer–Lambert law: dispersion theory, the concentration law of the refra

Ep. 46: Live from Pittcon with Award Winners Bob Pirok and Justin Godinho
In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with two recent award winners live from the Pittcon conference in San Antonio, Texas: Dr. Bob Pirok and Dr. Justin Godinho. Dr. Bob Pirok is an Associate Professor at the University of Amsterdam in the Netherlands, where he also completed his Ph.D. under the direction of Professor Peter Schoenmakers. He is an expert in m

Ep 45: Overfitting in Chemometrics: Designing Models That Truly Work
Ep 45: Overfitting in Chemometrics: Designing Models That Truly Work by LCGC & Spectroscopy

Ep. 44: Be a Nice Person
In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Pierre-Hugues (PH) Stefanuto who is an Associate Professor and Lead Scientist in the Molecular System Research Unit at University of Liège in Liège, Belgium. He previously received both his M.S. and Ph.D. degrees from the same institution. Following his graduate work in Liege he was a postdoctoral research fello

EP 43: An Introduction to Optical Photothermal Infrared (O-PTIR) Spectroscopy
Here in Episode #43, podcast host Dr. Jerry Workman speaks with Dr. Mustafa
Kansiz, who is currently the Director of Product Management at Photothermal
Spectroscopy Corporation in Santa Barbara, California. They will be discussing an
introduction to optical photothermal infrared (O-PTIR) spectroscopy; the
technique, its applications and the newest innovations in O-PTIR and even
Phot

Ep. 42: Did You Look at the Raw Data?
In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Professor Kelly Hines. Dr. Hines is an associate professor in the Department of Chemistry at the University of Georgia in Athens. She received her B.S. degree in Chemistry from the University of Florida, and then completed the Ph.D. in Chemistry at Vanderbilt University. Her doctoral studies focused on monitoring bi

Ep 41: The Story of the Michelson Exhibit at the Angels Camp Museum
Here in Episode #41, podcast host Dr. Jerry Workman speaks with Sunil Mehrotra and Doug Modlin, who are the project leaders of the Albert Michelson Exhibit at the Angels Camp Museum located in Angels Camp, California. They will be discussing the life and times of Albert Michelson and the creation of the Albert Michelson Angels Camp Museum Exhibit. Albert A. Michelson was the first Nobel Laureate i

Ep. 40: Curiosity, Collaboration, and Open-Mindnesses are the Keys
In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Professor Luis Colon. Dr. Colon is is the SUNY Distinguished Professor, A. Conger Goodyear Professor, and Associate Dean for Inclusive Excellence in the College of Arts and Sciences at the University at Buffalo. He received his bachelors degree from University of Puerto Rico at Cayey, and then received the Ph.D. fro

Ep. 38: Being prepared isn’t just for Boy Scouts
Dr. Wilson is a research chemist and coordinator of the Cannabis Research Program in the Chemical Sciences Division at the National Institute of Standards & Technology (NIST) in Gaithersburg, Maryland. He received his B.S. degree in Chemistry from Greensboro College followed by a M.S. degree in Chemistry from the same institution. He then moved south to pursue a Ph.D. in Chemistry at the Universit

Ep 39: Space and Spectroscopy: Two Very Important Things
Here in Episode #39, podcast host Dr. Jerry Workman speaks with Dr. Macarena Garcia Marin, who is an astrophysicist and instrument scientist for the European Space Agency based at the Space Telescope and Science Institute in Baltimore, MD USA. She will be discussing the highlights of the role of the James Webb Space Telescope, also known as JWST, and its abilities and discoveries using the science

Ep 37: On the Subject of Flow Imaging Microscopy in Collaboration with the American Association of Pharmaceutical Scientists
Here in Episode #37, podcast host Dr. Jerry Workman speaks with Dr. Austin Daniels, application scientist for Yokogawa Fluid Imaging Technologies. This Episode will focus on flow imaging microscopy (FIM), a new technology for subvisible particle characterization in biologics.
We have invited Austin to our Analytically Speaking podcast to discuss the current trends and state of using FIM to ensure

Ep. 36: A Day in the Life of a NIST Scientist
In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Alix Rodowa, Research Chemist within the Organic Chemical Metrology Group at the National Institute of Standards & Technology (NIST) in Gaithersburg, Maryland. At NIST, she is the Environmental Sector Task Lead for the Organic Analysis Working Group for the Consultative Committee for Amount of Substance: Metrolo

Ep 35: On the Subject of Continuing Education for Spectroscopists.
Here in Episode #35, podcast host Dr. Jerry Workman speaks with Dr. Ellen V. Miseo, who has been active in vibrational spectroscopy and instrument development her entire career and is formally trained as a physical chemist. She has worked for instrument companies as well as run laboratory operations. She is past president of both the Coblentz Society and Society for Applied Spectroscopy and curren

Ep. 34: A Banner Year for Separation Science at Pittcon 2025
Perrault Uptmor of William & Mary, and Dr. Emanuela Gionfriddo of SUNY at Buffalo. Kate and Emanuela are both returning guests of the pod (see episodes 2 and 14), and joined us on-site at the Boston Convention Center to reflect on what we saw and heard at Pittcon 2025.
In a wide-ranging conversation, we touch on a variety of aspects of the Pittcon experience, including networking opportunities,

Ep. 32: Don’t skip seminar…you might miss a life-changing event
In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Benjamin Garcia. Dr. Garcia is the Raymond H. Wittcoff Distinguished Professor and Head of the Department of Biochemistry and Molecular Biophysics in the School of Medicine at Washington University in St. Louis. His research interests primarily focus on the development of mass spectrometry-based proteomic approa

Ep 33: Automating Chemometrics for an Expert Calibration System
Here in Episode #33, podcast host Dr. Jerry Workman speaks with Dr. Brian G. Rohrback, President of Infometrix, Inc. in Bothell, WA, USA—who has been active in chemometrics research and creating software for complex calibrations and multivariate data analysis since 1983. Infometrix was founded by researchers Bruce Kowalski and Gerry Erickson in 1978. We have invited Brian to our Analytically Spea

Ep 31: Clarifying the Meaning of Chemometrics in the World of Artificial Intelligence (AI)
Here in Episode #31, podcast host Dr. Jerry Workman speaks with Dr. Barry M. Wise, Founder and President of Eigenvector Research, Inc. about the meaning of the terms chemometrics, artificial intelligence (AI), machine learning (ML), and neural networks (NNs) within the context of analytical chemistry and process analysis.

Ep. 30: The Potential of Generative A.I. as a Research Assistant for Measurement Science
In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Farooq Wahab, Research Engineering Scientist at the University of Texas at Arlington. Wahab has interests and expertise in chiral separations, improving the green-ness of chromatographic separations, new detectors for chromatography such as microwave rotational spectroscopy, and new techniques for signal process

Ep 29: Quantitative Spectroscopy and Wave Optics in Infrared Spectroscopy
Here in Episode #29, podcast host Dr. Jerry Workman speaks with Dr. Thomas Mayerhöfer from the Leibniz Institute of Photonic Technology in Jena, Germany, about quantitative spectroscopy and wave optics in infrared spectroscopy, including the theory, simulation, and modeling aspects.

Ep. 28: What does industry want new chemists to know?
In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Molly Atkinson, Assistant Professor of Chemistry at the University of North Texas in Denton, TX, and her graduate student David Hamilton. Atkinson and Hamilton are experts in Chemistry Education Research (CER), and they recently published a paper discussing results of a survey of bachelors-level chemists working

Ep 27: Exploring the World of Spectroscopy for Portable and Wearable Systems: Technology and Apps
Here in Episode #27, podcast host Dr. Jerry Workman speaks with Dr. Richard Crocombe of Crocombe Spectroscopic Consulting, about the world of ever shrinking spectrometers. We explore the technologies and applications for such portable and wearable systems and the future of spectroscopy in our everyday lives.

Ep 26: HPLC2024 Conference Recap
In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias discuss highlights and observations from the recently completed HPLC2024 that was held in Denver, Colorado in July. The “HPLC Meeting”, as the conference is affectionately known by regular attendees, is widely regarded as the premier venue to discuss the latest advances in liquid chromatography research and applications, and

Ep 25: How to Interpret Infrared Spectra and How to Develop a Specialized Infrared Analyzer
Here in Episode 25, podcast host Dr. Jerry Workman speaks with Dr. Brian C. Smith about the challenges of training scientists to interpret infrared spectra and how to leverage that expertise into building a specialized instrument for analysis of Cannabis.

Ep 24: For the Love of Separation Science
In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Andre de Villiers, Professor of Chemistry at Stellenbosch University in South Africa. Dr. de Villiers is an expert in multi-dimensional chromatography and leads a research program mainly focused on the use of two-dimensional liquid chromatography coupled with mass spectrometric detection for the deep characteriz

Ep 23: Color My World: The Complexities of Color Measurements
Welcome to “Analytically Speaking,” the podcast from LCGC International and Spectroscopy.
Here in Episode #23, podcast host Dr. Jerry Workman speaks with Dr. Art Springsteen and Dr. David Wyble about the challenges of creating color standards and making color measurements using optical spectroscopy.

Ep. 22: Around the world with The Multidimensional Chromatography Workshop
In this episode, podcast host Dr. Dwight Stoll talks with Dr. Katelynn Perrault Uptmor, Dr. Pierre-Hugues Stefanuto, and Dr. Petr Vozka about the multidimensional chromatography workshop, better known as the MDCW for short. Kate, PH, Petr, and Dwight are co-organizers of the MDCW workshop, which was held most recently at California State University, Los Angeles. In their conversation they discuss

Ep 21: Using Reference Standards for Spectroscopic Measurements
Here in Episode 21, podcast host Dr. Jerry Workman speaks with Dr. Art Springsteen about the history and challenges associated with reflection and color standards used around the world for optical spectroscopy.

Ep. 20: Using multi-dimensional gas chromatography to help people breathe easier
In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Heather Bean, Associate Professor of Biomedicine and Biotechnology at Arizona State University. Dr. Bean is an expert in volatilomics and leads a research program focused on the use of omics approaches to better understand a variety of physiological conditions ranging from disease and illness, such as cystic fib

Ep 19: Atomic Spectroscopy: Searching for Life in all the Right Places
Here in Episode #19, podcast host Dr. Jerry Workman speaks with Dr. Andreas Riedo about the new developments in atomic spectroscopy, particularly those related to new advances in the field of space research.

Ep. 18: Teaching it forward in separation science
In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Kevin Schug, Shimadzu Distinguished Professor of Analytical Chemistry at the University of Texas, Arlington. Dr. Schug is an expert in separations and mass spectrometry, and leads a research program with diverse interests ranging from clinical analysis to environmental analysis. In their conversation, they discu

Ep. 17: What’s New in the Field of Atomic Spectroscopy
Here in Episode 17, podcast host Dr. Jerry Workman speaks with Dr. Jake Shelley about the latest developments and research in the field of atomic spectroscopy.
Dr. Jake Shelley is the Alan Paul Schulz Professor of Chemistry in the Department of Chemistry and Chemical Biology at Rensselaer Polytechnic Institute (RPI) in Troy, New York. Shelley’s research explores new hardware and software tools fo

Ep. 16: If you’re not having fun while learning, it’s time to study something else
In this episode, podcast host Dr. Dwight Stoll talks with Dr. David Bell, Research Fellow at Restek Corporation in Bellefonte, PA. Dr. Bell is an expert in the chemistry of stationary phases used for chromatography, and has contributed to all aspects of the lifecycle of commercial columns for chromatography, including research, development, and applications. In their conversation, they discuss Dr.

Ep. 15: Building Professional Spectroscopy Skills and Valuable Networks with the Coblentz Society
Welcome to “Analytically Speaking,” the podcast from LCGC and Spectroscopy.
Here in Episode 15, podcast host Dr. Jerry Workman talks to Dr. Ellen Miseo and Dr. Zac Schultz about the benefits of participating in the Coblentz Society.
Ellen has been involved in vibrational spectroscopy and instrument development her entire career and is trained as a physical chemist. She has worked for instrument

Ep. 14: The more diverse is your toolbox, the more analytical problems you can solve
In this episode, podcast host Dr. Dwight Stoll talks with Dr. Emanuella Gionfriddo, associate professor in the Department of Chemistry at the University of Toledo, Ohio. Dr. Gionfriddo is an expert in bioanalysis and analyte extraction technologies, and works on both the development of new technologies, and the application of those technologies to contemporary analytical challenges. In their conve

Ep 13: Recent Advances in Fluorescence Spectroscopy: Standards and Applications.
Welcome to “Analytically Speaking,” the podcast from LCGC and Spectroscopy.
Here in Episode 13, podcast host Dr. Jerry Workman talks to Dr. Paul C. DeRose, who is a senior research chemist at the National Institute of Standards and Technology (NIST) and leads the NIST Biochemical Science Division's project in luminescence standards development for chemical analysis and assay validation.
We spo

Ep. 12: Hyphenating Organoids with Chromatography
In this episode, podcast host Dr. Dwight Stoll talks with Dr. Steven Ray Wilson, a professor in the Department of Chemistry at the University of Oslo, Norway. Dr. Wilson is an expert in bioanalysis and has developed many innovative approaches for targeted and untargeted analysis of biomolecules, often in complex matrices such as biofluids. Most recently he has worked at the forefront of the rapidl

Ep. 11: Advancing NIR Spectroscopy Research and Applications
Welcome to “Analytically Speaking,” the podcast from LCGC and Spectroscopy.
Here in Episode 11, podcast host Dr. Jerry Workman talks to Prof. Yukihiro (Yuki) Ozaki, who is a professor emeritus in the School of Science and Technology at Kwansei Gakuin University in Japan. He has been a guest professor or scientist at Kobe University and the Toyota Physical and Chemical Research Institute.
We spo

Ep. 10: From the Ground Floor to HILIC – A Life in the HPLC Column Business
In this episode, podcast host Dr. Dwight Stoll talks with Dr. Richard Henry, an expert in HPLC column technology who has had a long and productive career in the HPLC column business. They discuss Dr. Henry’s early experiences with analytical chemistry and liquid chromatography working for DuPont and Spectra-Physics, and eventually the launch and success of the company he founded in 1985, Keystone

Ep. 9: Automating Advanced Chemometric Methods for Data Processing
Welcome to “Analytically Speaking,” the podcast from LCGC and Spectroscopy.
Here in Episode 9, podcast host Jerry Workman speaks to Prof. Rasmus Bro, who is a full professor at the University of Copenhagen and one of the foremost active living data analytics and chemometrics experts.
We spoke to Prof. Bro about the world of data analysis used for spectroscopy and other analytical methods. Over

Ep. 8: Analytical science is critical to staying ahead of chemical counterfeiters
In this episode, podcast host Dr. Dwight Stoll talks with Dr. Mary Ellen McNally, a Global Research and Development Fellow at FMC Corporation, in Newark, Delaware. They discuss the origins of her interest in separation science and her short stay in an anti-doping laboratory on her way to a long and distinguished career in industry. Dr. McNally shares her perspectives on the challenges associated w

Ep. 7: At the Scene of the Crime: Using Spectroscopy for Forensic Analysis
Here in Episode 7, podcast host Jerry Workman speaks with Professor Igor K. Lednev who is a Distinguished Professor of Chemistry at the University at Albany at the State University of New York. We have invited Professor Lednev to our Analytically Speaking podcast to discuss his research on the various applications of Raman spectroscopy for the identification and analysis of biological fluid stains

Ep. 6: Sometimes “Negative Results” Turn Out To Be the Most Interesting Ones
In this episode, podcast host Dr. Dwight Stoll talks with Dr. Adrian Clarke, Global Analytical Network Leader at Novartis Pharma in Basel, Switzerland. They discuss the origins of his interest in separation science, the evolution and maturation of supercritical fluid chromatography and its use in the pharmaceutical industry, and the dramatic growth in learning about separations of synthetic oligon

Ep. 5: New Software Tools for Analysis of Spectroscopic Data
Here in Episode 5, podcast host Jerry Workman speaks with Dr. Paul Gemperline who is Dean of the Graduate School and faculty member in the Department of Chemistry at East Carolina University in Greenville, North Carolina. We have invited Paul to our Analytically Speaking podcast to discuss his research on development of new computer algorithms and software tools for analysis of multivariate spectr

Ep. 4: The Future of Method Development for Liquid Chromatography
In this episode, podcast host Dr. Dwight Stoll talks with Dr. Deirdre Cabooter, a professor working in the Department of Pharmaceutical and Pharmacological Sciences at KU Leuven in Leuven, Belgium, about her pathway to separation science, her research on fundamental aspects of band broadening in liquid chromatography and emerging work on the use of machine learning in method development, and her w

Ep. 3: The Future of Chemometrics—Data-Driven Measurements and Instruments for Chemistry
Welcome to “Analytically Speaking,” the new podcast from LCGC and Spectroscopy.
Here in Episode 3, podcast host Jerry Workman talks to talks to Prof. Karl Booksh of the Department of Chemistry and Biochemistry at the University of Delaware, Newark, who is an expert in Raman and Raman imaging, LIBS, fluorescence, portable chemical sensors, miniaturization of analytical devices, and data driven sci

Ep 2: We Really Feel the Need to Know What’s in Stuff
In this episode, podcast host Dr. Dwight Stoll talks with Dr. Katelynn Perrault, an Associate Professor of Forensic Science and Chemistry at Chaminade university in Honolulu, about her pathway to separation science, her research on the composition of odors from decomposing remains, and her thoughts about what the separation science community can do to get more women involved in the field. Drs. Sto

Ep. 1: Transmission Infrared Imaging Microscopy (with Data Analytics)
Welcome to “Analytically Speaking,” the new podcast from LCGC and Spectroscopy.
Here in Episode #1, podcast host Jerry Workman talks to Prof. Barry Lavine of the Department of Chemistry at Oklahoma State University. Prof. Lavine and his research group have been working on new approaches and algorithms for identification and classification of samples measured using infrared (IR) imaging microscopy

Ep. 0: Analytically Speaking—The Exciting New Podcast from LCGC and Spectroscopy
Welcome to “Analytically Speaking,” the new podcast from LCGC and Spectroscopy.
In this preview (episode 0), Laura Bush talks with the two people who will share duties as the hosts of the new podcast:
• Dr. Dwight Stoll, a professor of chemistry at Gustavus Adolphus College in St. Peter, Minnesota, and
• Dr. Jerry Workman, a spectroscopist, noted author, and the Senior Technical Editor of Spect
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