Home Podcasts Extend Podcast with Darshan Shah, MD
Extend Podcast with Darshan Shah, MD

Extend Podcast with Darshan Shah, MD

Darshan Shah, MD 171 Episodes Jul 2, 2026

Extend with Darshan Shah, MD is a podcast focused on extending healthspan through cutting-edge science, research, tools, and protocols. Hosted by Dr. Darshan Shah, a board-certified surgeon with training from prestigious institutions, the show features interviews with world-renowned medical practitioners and thought leaders. It also includes weekly solo episodes with actionable advice for proactive disease prevention and health optimization.

Episodes

178. Dr. Matt Kaeberlein: The Science, Risk, and Hype Behind Today's Longevity Trends Jul 2, 2026 01:14:07 If you care about longevity, you have probably seen the same pattern over and over again. A new peptide, supplement, biological age test, off-label drug, or protocol starts gaining attention, and suddenly it sounds like the missing piece everyone should be using. The hard part is not wanting to be proactive. The hard part is knowing which claims have real evidence behind them, which ones are still
177. Dr. Jila Senemar: The Hormone Conversation Women Should Have Before Menopause Jun 30, 2026 41:31 A lot of women are taught to think about hormones only when something becomes impossible to ignore. Painful periods. Birth control decisions. Fertility anxiety. Postpartum changes. Perimenopause symptoms. Menopause. But what if those are not separate conversations? What if the body has been giving clues for years before the symptoms become loud enough to finally get attention? In this episode, I s
176. Dr. Labib Ghulmiyyah: What Fertility Can Reveal About Your Long-Term Health Jun 25, 2026 57:01 When a couple is trying to get pregnant and it is not happening, the conversation can become very intense very quickly. Suddenly, you are hearing about IVF, egg freezing, AMH, sperm count, hormones, age, cost, and timing. But before the conversation jumps straight to the next procedure or the next number to panic over, there may be a deeper question worth asking: What is fertility trying to tell u
175. Justin Roethlingshoefer: Why Your Body Needs More Than "Healthy Habits" To Heal Jun 23, 2026 52:35 Your body is constantly repairing, renewing, and rebuilding itself. Hundreds of millions of cells are replaced every few months, which sounds incredible until you ask the question most people skip: if the body is designed to heal, why do so many people still feel tired, foggy, inflamed, slow to recover, or like something is off even when they are doing so many of the "right" things? In this episod
174. Dr. Dave Rabin: Why Being Human Feels Harder Than It Should in 2026 Jun 18, 2026 01:01:22 A lot of people are trying to do the right things. They are learning more, tracking their health, working on their stress, trying to be more present, and using the tools they have been told should help. But if the advice is available, the science is clearer than ever, and the tools are right in front of us, why do so many people still feel overwhelmed, burned out, disconnected, or unable to make t
173. Brian Le Gette: The Hidden Reason Your Body Struggles To Heal Jun 16, 2026 59:35 When your body feels wired, depleted, foggy, inflamed, or slow to recover, the usual instinct is to add something else. Another supplement. Another device. Another protocol. But the body does not respond to tools just because they are available. It responds to the signals it is receiving, and if those signals keep telling the body it is under threat, it will keep prioritizing survival over repair.
172. Dr. William Von Hippel: The Connection-Autonomy Paradox: Why More Freedom Can Make Us Feel More Alone Jun 11, 2026 50:49 Modern life tells us that more freedom should make us happier. More independence, more control, more convenience, more space to do life on our own terms. But what if the thing we keep chasing is also the thing quietly pulling us away from what our brain and body still need most: connection. In this episode of Extend, I sit down with Dr. William Von Hippel to talk about the conflict between two of
171. Dr. Kristen Holmes: The Sleep Debt Problem Affecting Your Brain, Mood, and Relationships Jun 9, 2026 59:14 Sleep debt is usually treated like a personal problem. You sleep less, feel tired, and try to catch up later. But Dr. Kristen Holmes explains why that belief is too small. When your body is missing the sleep it actually needs, it can affect your mental control, emotional regulation, leadership, and even how safe the people around you feel in your presence. In this episode of Extend, I sit down wit
170. Dr. Sonya Jensen: The Hormone-Trauma Connection: Why Midlife Symptoms Are Not Just Physical Jun 4, 2026 57:11 Hormone symptoms are usually treated like a problem with levels. Progesterone is low. Estrogen is shifting. Cortisol is high. Testosterone is dropping. So the conversation often becomes about what to replace, what to supplement, or what protocol to follow. But there is a deeper layer that rarely gets brought into the room: the body is also responding to the stress, grief, resentment, trauma, peopl
169. Natalie Lefevre: How to Find the Toxins Blocking Your Body's Ability to Heal Jun 2, 2026 46:38 You can do the supplements, the IVs, the sauna, the clean eating, and the wellness routine, but if your body is still being exposed to toxins every day, you may be cleaning up a mess while the tap is still running. That is what makes toxic load so frustrating. It can hide in your water, food, air, dental work, travel habits, mold exposure, heavy metals, PFAS, pesticides, microplastics, and even th
168. Peter Crone: Why You Can't Access True Vitality Until You Free Your Mind May 28, 2026 55:34 When we talk about health, longevity, and performance, the conversation often starts with the body. We look at biomarkers, sleep, nutrition, exercise, recovery, and protocols, hoping that if we get enough of the physical pieces right, we will finally feel better, stronger, and more alive. Yet there is another layer that can quietly shape everything from the way we handle stress to the way we heal,
167. Dr. Amie Hornaman: The Thyropause Problem: Why So Many Women Feel Off in Midlife Despite "Normal" Labs May 26, 2026 55:59 Have you entered midlife and started gaining weight, feeling exhausted, waking up foggy, losing motivation, or noticing your mood shift while your labs keep coming back "normal"? For a lot of women over 40, that answer does not bring relief because they still feel off, and this episode explains why thyropause, the midlife decline in thyroid function, is so often missed, dismissed, or mistaken for

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