Home Podcasts Depresh Mode with John Moe
Depresh Mode with John Moe

Depresh Mode with John Moe

John Moe, Maximum Fun 294 Episodes Sep 21, 2026

Join host John Moe for honest, relatable, and sometimes funny conversations about mental health. Hear from comedians, musicians, authors, and actors about living with depression, anxiety, and other common disorders. The show also features insights from mental health experts, offering practical advice and reducing stigma.

Episodes

Mental Illness Before and After Pregnancy with Dr. Kara Zivin, Who Has Been There
Mental Illness Before and After Pregnancy with Dr. Kara Zivin, Who Has Been There Sep 21, 2026 00:48:23 There has been a great deal of press coverage of the Lindsay Clancy case lately. What the world needs more of is first-hand experiences of severe mental health problems both before and after a baby is born. Dr. Kara Zivin is a researcher and professor of psychiatry at the University of Michigan. While pregnant with her son 15 years ago, she experienced a profound depression that turned suicidal. T
Singer Nicole Atkins Doesn’t Recommend Insomnia, Alcoholism, Falling Down Sinkholes
Singer Nicole Atkins Doesn’t Recommend Insomnia, Alcoholism, Falling Down Sinkholes Sep 14, 2026 00:47:08 The acclaimed singer and songwriter Nicole Atkins is pretty adept at reading clues that something is wrong. After she’d fall asleep on a Saturday and wake up on Monday, she knew it was time to get more aggressive about addressing her insomnia. Years before, a fall down an actual sinkhole made her realize that drinking had become a pretty big problems. On Nicole’s new album Drama, her first in five
AI Chatbots Destroyed His Reality. Dr. Jeremy Heffner Explains Why He Believed Them.
AI Chatbots Destroyed His Reality. Dr. Jeremy Heffner Explains Why He Believed Them. Sep 7, 2026 01:03:54 Dr. Jeremy Heffner was a highly educated, high achieving surgeon. Not the kind of person one would expect to slide down an AI chatbot-generated rabbit hole, lose touch with reality, and give credence to the bot’s suggestion that he was one of the three smartest humans ever. But that’s what happened. The bots also told him there was a 70% chance AI would end the world and only Jeremy could save it.
Best of Depresh Mode: Cameron Esposito on Comedy, Rehab, and Bipolar Disorder
Best of Depresh Mode: Cameron Esposito on Comedy, Rehab, and Bipolar Disorder Aug 31, 2026 00:44:45 Cameron Esposito has many titles: hugely successful standup comedian, actor in television and film, writer, podcast host. After a recent rehab stay led to a mental health diagnosis, she has realized that she’s also a person with bipolar disorder, type II. Cameron has a new special, Four Pills, that’s part stand-up comedy and part reflection on the circumstances that led to this discovery as well a
Cat Grief is Real. So is Human Grief. We’re Underestimating and Misunderstanding Both.
Cat Grief is Real. So is Human Grief. We’re Underestimating and Misunderstanding Both. Aug 24, 2026 01:04:00 Bay Area journalist s.e. smith thinks the high school goths were right: we should be talking about death all the time. It’s underdiscussed for something that will literally affect us all. And in that silence, they say, things get worse: the topic becomes less approachable, inevitable periods of grief can become more chaotic and disruptive, and the actual pain of losing your person or cat or dog ca
Oh, It’s Autism, Mary H.K. Choi Learned at 43. Okay, She Thought, That Explains a Lot.
Oh, It’s Autism, Mary H.K. Choi Learned at 43. Okay, She Thought, That Explains a Lot. Aug 17, 2026 01:07:13 Mary H.K. Choi compares living with her brain to just not understanding the operating system on a computer. She didn’t know if this was a result of trauma and neglect in her childhood, the experience of being parentified as a child, grief after the death of her father, or what. So she spent decades of effort and piles of dollars to figure it out. She did cognitive behavioral therapy, internal fami
Margaret Glaspy Ends Her Instagram Addiction and Sings From Her Original Thought
Margaret Glaspy Ends Her Instagram Addiction and Sings From Her Original Thought Aug 10, 2026 01:02:29 Margaret Glaspy compares the experience she was having on Instagram to being lightly punched in the gut, over and over, for a very long time. Like it’s not like being hit hard, just a little tap of something negative with each update you read, each comparison made, each distancing away from actual humanity and toward the simulated reality the platform presents. So she quit social media. Which was
Depression, Loneliness, and Memory Problems Are Worse In Middle Age, But Only in America
Depression, Loneliness, and Memory Problems Are Worse In Middle Age, But Only in America Aug 3, 2026 00:49:39 For most of the world, the advent of middle age does not make depression, loneliness, and memory issues more of a problem than earlier in life. In some countries, things actually get better. The only nation on earth where it all gets worse is right here in the USA. Arizona State University psychologist Frank Infurna has been researching this topic extensively and explains the uniquely American soc
Codependency and Covid on a Tiny Boat in the Middle of the Ocean, with Angela Harger-Thompson
Codependency and Covid on a Tiny Boat in the Middle of the Ocean, with Angela Harger-Thompson Jul 27, 2026 00:59:10 Angela Harger-Thompson had moved to Hollywood to make it big in showbiz but soon fell victim to a devastating assault. There to comfort her was her intermittent boyfriend. She really liked him and thought his offer of a four-week, 4000 mile sailing voyage on the Pacific Ocean, accompanies by a small crew of strangers and a dog seemed like a good idea. The claustrophobic pressure of that situation,
Maybe It IS Time to Panic Over AI Chatbots and Mental Health with Maggie Harrison Dupré
Maybe It IS Time to Panic Over AI Chatbots and Mental Health with Maggie Harrison Dupré Jul 20, 2026 00:55:05 This week, we take a look at a couple of acronyms that are soaring in popularity and ask what their widespread adoption means for mental health. Maggie Harrison Dupré of Futurism has been following the AI space closely and has an update on lawsuits related to chatbots’ culpability in numerous cases of attempted and completed suicides. She also explains some recent research about why prolonged enga
Jo Dee Messina on Hard Times, Jesus, and Her First Album in 12 Years
Jo Dee Messina on Hard Times, Jesus, and Her First Album in 12 Years Jul 13, 2026 00:51:21 Jo Dee Messina has a long career in the music industry: number one hits, platinum and gold records, many awards. She’s a country music icon. Jo Dee just released Bridges, her first new album in 12 years and those were 12 years filled with some tough times. Her marriage ended, leaving her as a single mom of two boys, both her parents died, and Jo Dee battled cancer, completed treatment, and is canc
Best of Depresh Mode: Hanif Abdurraqib on Cultivating a Support System, Depression, Anxiety, and Basketball
Best of Depresh Mode: Hanif Abdurraqib on Cultivating a Support System, Depression, Anxiety, and Basketball Jul 6, 2026 00:50:35 Hanif Abdurraqib is a MacArthur Fellow, accomplished poet, and critically lauded author of numerous books, including There’s Always This Year: On Basketball and Ascension, which is now out in paperback. He’s also a person who deals with major depressive disorder and numerous anxiety disorders. In a revealing, positive, and practical interview, Hanif talks about the numerous ways he cares for his m

Recommended