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Depresh Mode with John Moe

Depresh Mode with John Moe

John Moe, Maximum Fun 294 episodes Nov 9, 2026

Join host John Moe for honest, relatable, and sometimes funny conversations about mental health. Hear from comedians, musicians, authors, and actors about living with depression, anxiety, and other common disorders. The show also features insights from mental health experts, offering practical advice and reducing stigma.

Episodes

ECT Isn’t Like in One Flew Over the Cuckoo’s Nest. Ted Scheinman Tells What It Is Like.
ECT Isn’t Like in One Flew Over the Cuckoo’s Nest. Ted Scheinman Tells What It Is Like. Nov 9, 2026 45:48 Electroconvulsive Therapy (ECT) is not the first place to turn if you’re experiencing symptoms of major depressive disorder. Any doctor would want you to try talk therapy, medications, just about anything else before turning to a treatment that runs an electrical current through your brain, causing a generalized convulsion. That said, the treatment, if it comes to that, is very effective, with a b
Politics Makes Us More Depressed. Let’s Figure Out Why and What To Do About It.
Politics Makes Us More Depressed. Let’s Figure Out Why and What To Do About It. Nov 2, 2026 38:47 As America goes to the polls for the midterm elections and balances hope and fear and general agitation as a result, we take a look at what politics and political rhetoric affect your depression levels, whether you deal with major depressive disorder or just encounter a feeling of hopelessness in the face of the contemporary political reality. Political Scientist Christopher Ojeda from University
Grieving the Life You Didn’t Get to Live, with Megan Devine
Grieving the Life You Didn’t Get to Live, with Megan Devine Oct 26, 2026 01:03:08 Megan Devine, author, psychotherapist, and one of the top grief experts today, wants you to know that grief is normal. It’s not a mental illness. That’s not to say grief is easy, of course, it’s absolutely not. And it isn’t to say grief is simple because it’s not that either. It’s powerful and complicated, so much so that it can mean grieving for what your own life could have been but wasn’t. If y
E (from Eels) Talks Art, Persistence in the Face of Tragedy, and Cookie Monster
E (from Eels) Talks Art, Persistence in the Face of Tragedy, and Cookie Monster Oct 19, 2026 49:04 “Me no cry because cookie is finished,” Cookie Monster once said. “Me smile because cookie happened.” Eels has been a band for 35 years and just dropped their 16th studio album, with the Cookie Monster-inspired title Cookie Happened. In that time, Mark Oliver Everett (aka E) has been the only constant, writing and perform songs that can be, at times, deeply moving, sly funny, and just about everyt
Showbiz! For Murray Hill, it’s an Industry, Memoir, and Mantra
Showbiz! For Murray Hill, it’s an Industry, Memoir, and Mantra Oct 12, 2026 01:03:45 Audiences know Murray Hill as the hilarious pencil-mustachioed guy who looks like a Catskills comedian. Much of that identity was deliberately formed after an abusive childhood where he was raised as a girl and sure didn’t feel like one. He grew up, broke hard with the past, named himself for the Manhattan neighborhood he landed in, and became a cabaret star. Which is great! But that trauma also m
Andy Frasco Is Figuring Out Who He IS When He’s NOT a Good Time Rock & Roll Frontman
Andy Frasco Is Figuring Out Who He IS When He’s NOT a Good Time Rock & Roll Frontman Oct 5, 2026 01:02:46 Andy Frasco has been hard at work since the age of 13. As an adolescent that meant booking shows, helping out at record labels, running a flag football business. When he was 19, he took his carefully saved Bar Mitzvah money, bought a van, skipped college, and went on tour with his band. Now 38, he’s basically been on that tour ever since, using big energy and charisma to provide the funk and fun w
Gabrielle Moss On Midlife Plot Twists and Just Not Talking To Your Mom Anymore
Gabrielle Moss On Midlife Plot Twists and Just Not Talking To Your Mom Anymore Sep 28, 2026 48:27 Midlife doesn’t need to be a point of crisis, says author Gabrielle Moss. You don’t need to make dangerous choices, blow things up, take a spiritual trek through Nepal, or buy a red convertible. Her new book, Mid-Life Plot Twist, co-written with Lindsay Goldwert, explores how to set boundaries, re-evaluate relationships with work and money and love, and get on a better track. Gaby arrived at this
Mental Illness Before and After Pregnancy with Dr. Kara Zivin, Who Has Been There
Mental Illness Before and After Pregnancy with Dr. Kara Zivin, Who Has Been There Sep 21, 2026 48:23 There has been a great deal of press coverage of the Lindsay Clancy case lately. What the world needs more of is first-hand experiences of severe mental health problems both before and after a baby is born. Dr. Kara Zivin is a researcher and professor of psychiatry at the University of Michigan. While pregnant with her son 15 years ago, she experienced a profound depression that turned suicidal. T
Singer Nicole Atkins Doesn’t Recommend Insomnia, Alcoholism, Falling Down Sinkholes
Singer Nicole Atkins Doesn’t Recommend Insomnia, Alcoholism, Falling Down Sinkholes Sep 14, 2026 47:08 The acclaimed singer and songwriter Nicole Atkins is pretty adept at reading clues that something is wrong. After she’d fall asleep on a Saturday and wake up on Monday, she knew it was time to get more aggressive about addressing her insomnia. Years before, a fall down an actual sinkhole made her realize that drinking had become a pretty big problems. On Nicole’s new album Drama, her first in five
AI Chatbots Destroyed His Reality. Dr. Jeremy Heffner Explains Why He Believed Them.
AI Chatbots Destroyed His Reality. Dr. Jeremy Heffner Explains Why He Believed Them. Sep 7, 2026 01:03:54 Dr. Jeremy Heffner was a highly educated, high achieving surgeon. Not the kind of person one would expect to slide down an AI chatbot-generated rabbit hole, lose touch with reality, and give credence to the bot’s suggestion that he was one of the three smartest humans ever. But that’s what happened. The bots also told him there was a 70% chance AI would end the world and only Jeremy could save it.
Best of Depresh Mode: Cameron Esposito on Comedy, Rehab, and Bipolar Disorder
Best of Depresh Mode: Cameron Esposito on Comedy, Rehab, and Bipolar Disorder Aug 31, 2026 44:45 Cameron Esposito has many titles: hugely successful standup comedian, actor in television and film, writer, podcast host. After a recent rehab stay led to a mental health diagnosis, she has realized that she’s also a person with bipolar disorder, type II. Cameron has a new special, Four Pills, that’s part stand-up comedy and part reflection on the circumstances that led to this discovery as well a
Cat Grief is Real. So is Human Grief. We’re Underestimating and Misunderstanding Both.
Cat Grief is Real. So is Human Grief. We’re Underestimating and Misunderstanding Both. Aug 24, 2026 01:04:00 Bay Area journalist s.e. smith thinks the high school goths were right: we should be talking about death all the time. It’s underdiscussed for something that will literally affect us all. And in that silence, they say, things get worse: the topic becomes less approachable, inevitable periods of grief can become more chaotic and disruptive, and the actual pain of losing your person or cat or dog ca

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