Ophthalmology Journal
Join Ophthalmology's social media editors as they interview authors and editors of the American Academy of Ophthalmology's journal family: Ophthalmology, Ophthalmology Retina, Ophthalmology Glaucoma, and Ophthalmology Science.
Episodes
Depression and Anxiety After Topical Carbonic Anhydrase Inhibitors
Dr. Drew Carey speaks with Dr. Abdelrahman Elhusseiny on his study of the association between topical carbonic anhydrase inhibitor use and the development of depression and anxiety disorders in patients with glaucoma. From his Ophthalmology Science article, "Depression and Anxiety After Topical Carbonic Anhydrase Inhibitors." Elhusseiny A, et al. Depression and Anxiety After Topical Carbonic Anhyd
Lacquer Crack Visible Light OCT
Dr. Edmund Tsui interviews a team of researchers from New York University Grossman School of Medicine: Galen Hu, MD, Vivek Srinivasan, PhD, and Nitish Mehta, MD. The team discusses their case study which applied ultra-high resolution visible light optical coherence tomography towards acute and chronic lacquer cracks in a patient with pathologic myopia. From their Ophthalmology Science article, "In
Fuchs Endothelial Corneal Dystrophy and Cardiometabolic Comorbidities
Dr. Emily is Schehlein is joined by Dr. Clara C. Chan and medical student Andrew Mihalache to discuss their report that showed individuals with Fuchs' endothelial corneal dystrophy exhibited a higher burden of cardiometabolic disease than matched controls. From their Ophthalmology article, "Fuchs' Endothelial Corneal Dystrophy and Cardiometabolic Comorbidities." Mihalache A, et al. Fuchs' Endothel
Cardiovascular Risk and Eye Health
Dr. Rukhsana Mirza is joined Dr. Dr. Anne Coleman. They discuss Dr. Coleman's study evaluating whether the Pooled Cohort Equations cardiovascular risk scores are associated with the future development and can predict future development of age-related macular degeneration, glaucoma, diabetic retinopathy, retinal vein occlusion, and hypertensive retinopathy. From her Ophthalmology article, "Cardiova
Stroke Risk after Ischemic Ocular Events
Dr. Rukhsana Mirza interviews ophthalmology residents Drs. Rita Vought and Victoria Vought on their recent study investigating clinical characteristics that impact ischemic stroke or transient ischemic attack risk after the first retinal artery occlusion or amaurosis fugax among adults. From their Ophthalmology Retina article, "Stroke Risk after Ischemic Ocular Events: Insights from an Electronic
Ophthalmic Drug Shortages in the United States
How does a case of viral conjunctivitis lead to a study on ophthalmic drug shortages in the United States? Dr. Emily Schehlein finds out from Dr. Ian Pitha as they discuss his Ophthalmology article "Ophthalmic Drug Shortages in the United States: Survey of the University of Utah Drug Information Service Drug Shortage Database." Ophthalmic Drug Shortages in the United States: Survey of the Universi
Artificial Intelligence in Ophthalmology
A special episode hosted by Ophthalmology's Editor-in-Chief, Dr. Bennie Jeng. He is joined by Associate Editor Dr. Aaron Lee to announce our new special collection on Artificial Intelligence in Ophthalmology. They discuss how AI is already changing the practice of ophthalmology and medical publishing. Dr. Lee then outlines the types of articles we are looking for in our new special collection. For
Goniotomy Outcomes in the IRIS Registry
Dr. Emily Schehlein interviews Dr. Julia H. Joo and Dr. Ang Li on their study which used the IRIS® Registry to investigate the predictive factors for goniotomy success. From their Ophthalmology Glaucoma article, "Factors Associated with Goniotomy Outcomes in the United States." Factors Associated with Goniotomy Outcomes in the United States. Joo J, et al. Ophthalmology Glaucoma. 2026. In press.
A New Visual Field for Hydroxychloroquine Screening
Dr. Rajesh Rao interviews Dr. Michael Marmor on his recent Ophthalmology Retina editorial, A New Visual Field for Hydroxychloroquine Screening, and discuss the performance of the Humphrey 24-2C visual field test for detecting parafoveal and pericentral hydroxychloroquine retinopathy. A New Visual Field for Hydroxychloroquine Screening. Marmor M. Ophthalmology Retina, Volume 10, Issue 3, 221-222.
Systemic Workup in Isolated Paracentral Acute Middle Maculopathy
Dr. Drew Carey interviews Dr. Avner Hostovsky on his study evaluating the diagnostic yield of a structured systemic workup in patients presenting with acute visual symptoms who were diagnosed with isolated paracentral acute middle maculopathy (PAMM). From his Ophthalmology article, "High Yield of Systemic Workup in Patients with Acute Isolated Paracentral Acute Middle Maculopathy." Hostovsky A, Pe
Detecting Inflammation in Fundus Photos Using Machine Learning
Dr. Drew Carey is joined by Drs. S. Saeed Mohammadi and Quan Dong Nguyen, authors of Ophthalmology Science's "Detecting Inflammation in Fundus Photographs Using Machine Learning." They discuss their study investigating the use of AI in the diagnosis of uveitis from ultra-widefield fundus photographs. Detecting Inflammation in Fundus Photographs Using Machine Learning. Mohammadi S, Yavari N, Saengs
Hydrus Microstent Clinical Outcomes for Open-Angle Glaucoma
Dr. Thomas Johnson returns to the podcast. Dr. Emily Schehlein interviews him on his study to assess the clinical outcomes of Hydrus Microstent implantation with cataract extraction for the treatment of open-angle glaucoma. From the Ophthalmology Glaucoma article, Clinical Outcomes of Hydrus Microstent Implantation for Open-Angle Glaucoma: Results from a Large Academic Center. Clinical Outcomes o
ChatGPT-4o Responses to Patient Questions
How accurate is ChatGPT responding to patient questions at a 6th grade reading level vs. a 12th grade reading level? Find out in this episode as Drs. Rukhsana Mirza and Angelo Tanna discuss their Ophthalmology Science article, "Accuracy and Readability of Chat Generative Pre-Trained Transformer-4 Omni in Answering Ophthalmology Patient Questions." Accuracy and Readability of Chat Generative Pre-Tr
Autofluorescence in Retinal Detachments
Dr. Rukhsana Mirza sits down with Dr. Avni P. Finn to discuss her Ophthalmology Science article, "Ultra-Widefield Fundus Autofluorescence Findings as an Indicator of Duration in Rhegmatogenous Retinal Detachment," which used ultra-widefield color fundus photography and fundus autofluorescence to assess patients with rhegmatogenous retinal detachment, relating clinical features to imaging findings
Rate and Rationale for Vitrectomy after Pneumatic Retinopexy
Dr. Rajesh Rao interviews Dr. Bradley T. Smith on his study to report the rate and rationale for vitrectomy after retinal detachment repair with pneumatic retinopexy, from his Ophthalmology Retina article, "Rate and Rationale for Vitrectomy after Pneumatic Retinopexy." Rate and Rationale for Vitrectomy after Pneumatic Retinopexy. Smith, Bradley T. et al. Ophthalmology Retina, Volume 9, Issue 11, 1
Using AI LLMs For Extracting Eye Exam Findings from EHR Notes
With the current AI boom, physicians are looking for ways to use this new technology in their practices. Dr. Edmund Tsui interviews Dr. Sophia Y. Wang on her Ophthalmology Science article, "Leveraging Large Language Models with Sequential Prompting to Extract Eye Examination Findings from Free-Text Ophthalmology Notes," which showed that LLMs are capable of efficient, automated, and accurate extra
Ophthalmology Transfers to an Academic Trauma Center
Dr. Edmund Tsui is joined by Dr. Shu Feng, author of Ophthalmology's Assessing the Efficacy of Ophthalmic Transfers to an Academic Level 1 Trauma Hospital, to discuss her study of ophthalmic transfers to an academic level 1 trauma center and the accuracy of transferring diagnoses and rate of intervention after transfer. Assessing the Efficacy of Ophthalmic Transfers to an Academic Level 1 Trauma
American Glaucoma Society's 40th Anniversary
We're celebrating the American Glaucoma Society's 40th Anniversary! Dr. Emily Schehlein interviews three glaucoma luminaries, previous AGS Presidents, and guest editors for Ophthalmology Glaucoma's AGS 40th Anniversary special issue: Dr. Steven Gedde, Dr. Carla Siegfried, and Dr. Greg Skuta. Together they discuss the past, present, and future of the AGS, advancements in the treatment of glaucoma,
GLP-1RA Use and Risk of Neovascular AMD
It's our 100th episode! Dr. Rukhsana Mirza sits down with Drs. Aleksandra V. Rachitskaya and Kevin C. Allan to discuss their retrospective study using the TriNetX network to investigate the risk of neovascular age-related macular degeneration (AMD) in patients taking glucagon-like peptide-1 receptor agonists (GLP-1RAs). From their Ophthalmology Retina article, "Glucagon-Like Peptide-1 Receptor Ago
Adalimumab vs. Conventional Immunosuppression for Uveitis
Dr. Edmund Tsui and author Dr. Douglas A. Jabs discuss the results of the ADVISE Trial, designed to compare adalimumab to conventional immunosuppressive drugs for the treatment of non-infectious intermediate, posterior, and panuveitides. From Dr. Jab's Ophthalmology article, "Adalimumab vs. Conventional Immunosuppression for Uveitis (ADVISE) Trial." Adalimumab vs. Conventional Immunosuppression fo
Age-Related Macular Degeneration and the Gut Microbiome
Our newest host and Social Media Editor, Dr. Rukhsana Mirza, interviews Dr. Phoebe Lin. Together, they discuss Dr. Lin's study on whether an intestinal microbial signature is associated with advanced age-related macular degeneration and the relationship between the microbiota and AMD genetic risk. From her Ophthalmology Science article, "Age-related Eye Disease Studies Supplements and Genetic Risk
Elevated Intraocular Pressure after Cataract Surgery and Risk of Glaucoma
Dr. Emily Schehlein is joined by Dr. Cecilia S. Lee and Dr Parisa Taravati, authors of "Elevated Intraocular Pressure Immediately after Cataract Surgery and Future Risk of Primary Open-Angle Glaucoma in the IRIS® Registry (Intelligent Research in Sight)." Together they discuss the associations between postoperative intraocular pressure after cataract surgery and the future risk of developing prima
Outpatient Oral Doxycycline vs. IV Penicillin for Syphilitic Uveitis
Dr. Edmund Tsui interviews Dr. Brian C. Toy on his retrospective cohort study which shows that oral doxycycline clinical and serologic outcomes are comparable to IV penicillin for syphilitic uveitis, published in Ophthalmology. From "Outpatient Oral Doxycycline versus Intravenous Penicillin for Syphilitic Uveitis." Outpatient Oral Doxycycline versus Intravenous Penicillin for Syphilitic Uveitis. B
The CorNeat Everpatch and the Process of FDA Authorization
On September 5, 2025, the FDA issued a recall for the CorNeat EverPatch. Dr. Emily Schehlein is joined by Dr. Thomas V. Johnson to discuss his study on the early exposure and surgical revision rates of the CorNeat EverPatch. Later, Dr. Henry Jampel explains the difference between FDA clearance and FDA approval for medical devices. Dr. Johnson coauthored the Ophthalmology article, "Early Postoperat
Direct Selective Laser Trabeculoplasty in Open-Angle Glaucoma
Dr. Emily Schehlein sits down with author Dr. Nathan Congdon to break down the results of the GLAUrious Study on comparing automated, gonioscopy-free, noncontact, image-guided direct selective laser trabeculoplasty with conventional SLT in open-angle glaucoma and ocular hypertension to reduce intraocular pressure. From the Ophthalmology article, "Randomized Noninferiority Trial of Direct Selective
Epiretinal Membrane in Diabetic Patients
Dr. Rajesh Rao discusses the risk factors for epiretinal membrane formation in patients with diabetes mellitus with Dr. Shinji Kakihara, first author of the Ophthalmology Science article, "Epiretinal Membrane Is Associated with Diabetic Retinopathy Severity and Cumulative Anti-VEGF Injections." Epiretinal Membrane Is Associated with Diabetic Retinopathy Severity and Cumulative Anti-VEGF Injections
Pediatric Noninfectious Uveitis in the US
Dr. Edmund Tsui sits down with Drs. Akshay S. Thomas and Ogul E. Uner to discuss their IRIS Registry study of the prevalence, characteristics, and treatment patterns of pediatric noninfectious uveitis in the United States. From their Ophthalmology Retina article, "Prevalence, Treatment Patterns, and Outcomes of Pediatric Noninfectious Uveitis in the United States: An IRIS Registry Analysis" Preval
Real-Time Adverse Events in Pediatric Fluorescein Angiography
Previous research on the safety of fluorescein angiography in adults has indicated that severe complications are rare, but due to few studies in the pediatric population, the true rates of complications are unknown. Dr. Edmund Tsui sits down with Dr. Nimesh A. Patel to discuss his study examining fluorescein angiography adverse events in pediatric patients. From his Ophthalmology Retina article, "
Glaucoma Progression: Fear and Risk of Falling
Fall prevention is a major public health concern because of the physical and psychological risks associated with falls. Loss of visual function is a major risk factor for falls and may be a major contributor to fall risk among older adults. Dr. Emily Schehlein interviews Dr. C. Gustavo De Moraes and medical student Alexander F. Dagi on the relationships between rates of glaucomatous visual field p
Common Medications and Diabetic Macular Edema
Dr. Drew Carey interviews medical student Jawad Muayad and Dr. Sami S. Dahr on the impact of systemic medications, including glucagon-like peptide-1 receptor agonists, fenofibrates, thiazolidinediones, and calcium channel blockers, on the risk of developing diabetic macular edema in patients with type 2 diabetes mellitus. From their Ophthalmology Retina article, "Influence of Common Medications on
Outcomes of Uveoscleral Outflow Enhancement in Glaucoma Patients
Dr. Emily Schehlein interviews Dr. Ticiana De Francesco on the results of her case series evaluating the safety and efficacy of the scleral allograft–reinforced cyclodialysis in patients with primary open-angle glaucoma through 24 months of follow-up. From her recent Ophthalmology Science article, "Bio-interventional Uveoscleral Outflow Enhancement Surgery for Primary Open-Angle Glaucoma: 2-Year R
Hybrid Remote Monitoring of Corneal Grafts via OCT Pachymetry Maps
Just when you thought we ran out of ways use to Optical Coherence Tomography imaging, it turns out there's more! Dr. Matt Feng interviews Dr. Sotiria Palioura on her study to use anterior segment OCT pachymetry maps in the long-term monitoring of corneal grafts. From the Ophthalmology Science article, "Long-Term Monitoring of Corneal Grafts via Anterior Segment Optical Coherence Tomography Pachyme
Sleep Apnea and Age-related Macular Degeneration
What is the relationship between obstructive sleep apnea and the development and progression of age-related macular degeneration? Dr. Drew Carey talks with Dr. Ahmed M. Alshaikhsalama and Dr. Amer F. Alsoudi on their recent Ophthalmology Retina article, "Association between Obstructive Sleep Apnea and Age-related Macular Degeneration Development and Progression." Association between Obstructive Sl
Glaucoma Surgery SOS: Emergency Department Utilization
Dr. Emily Schehlein interviews Dr. Andrew W. Gross on his study to determine the frequency, timing, and findings of emergency department visits after glaucoma surgery and discuss strategies to improve postoperative care to avoid unplanned visits. From his recent Ophthalmology Glaucoma article, "Glaucoma Surgery SOS: Emergency Department Utilization Greater among Younger and First-Time Surgical Pat
AGS/AAO Position Statement on Nicotinamide Use for Glaucoma Neuroprotection
Dr. Emily Schehlein discusses recent guidelines from the American Glaucoma Society and the American Academy of Ophthalmology on Nicotinamide use for glaucoma neuroprotection with lead author, Dr. Aakriti Garg Shukla. Published in Ophthalmology Glaucoma, "American Glaucoma Society-American Academy of Ophthalmology Position Statement on Nicotinamide Use for Glaucoma Neuroprotection" American Glaucom
Should We Use Disposable Tonometers and Gonioprisms in the Office?
Single-use disposable plastics and other materials have increased in use since the start of the COVID-19 pandemic. This generates increased waste and cost in eye care. Dr. Emily Schehlein and Dr. Alan Robin discuss their recent Ophthalmology Glaucoma editorial, "Should We Use Disposable Tonometers and Gonioprisms in the Office?" with recommendations on how and why eye care professionals should cle
Anti-VEGF vs Panretinal Photocoagulation Laser Therapy for Diabetic Retinopathy
Dr. Rajesh Rao sits down with Dr. Sophie J. Bakri and medical student Marie-Michele Macaron to discuss their systematic Review and meta-analysis on the efficacy and safety of anti-VEGF and panretinal photocoagulation for the treatment of proliferative diabetic retinopathy. From their Ophthalmology Retina article, "Anti-VEGF Injections vs. Panretinal Photocoagulation Laser Therapy for Proliferative
Glaucoma Medications and Risk of Uveitis
Dr. Edmund Tsui interviews authors Dr. Muhammad Z. Chauhan and Dr. Krishna S. Kishor on the risk of uveitis among patients starting topical glaucoma therapy. From their Ophthalmology Glaucoma article, "Incidence of Uveitis Following Initiation of Prostaglandin Analogs versus Other Glaucoma Medications." Incidence of Uveitis Following Initiation of Prostaglandin Analogs versus Other Glaucoma Medica
Can ChatGPT Think Like An Ophthalmologist?
How accurate are diagnoses from ChatGPT? Can ophthalmologists distinguish between artificial intelligence and human responses? Dr. Tsui speaks with Drs. Jimmy S. Chen and David B. Granet on their Ophthalmology Science article, "Analysis of ChatGPT Responses to Ophthalmic Cases: Can ChatGPT Think like an Ophthalmologist?" Analysis of ChatGPT Responses to Ophthalmic Cases: Can ChatGPT Think like an
Vitreopapillary Findings in Nonarteritic Ischemic Optic Neuropathy
Dr. Drew Carey speaks with Dr. Tongalp H. Tezel on his study comparing patients with nonarteritic ischemic optic neuropathy (NAION) with healthy non-NAION patients with crowded discs and noncrowded optic discs. From his Ophthalmology article, "Vitreopapillary Findings in Nonarteritic Ischemic Optic Neuropathy versus Healthy Eyes." Vitreopapillary Findings in Nonarteritic Ischemic Optic Neuropathy
Therapeutic Interventions for Autoimmune Retinopathy
Dr. Edmund Tsui is joined by Dr. Majda Hadziahmetovic to discuss her meta-analysis and systematic review investigating the effectiveness of systemic and local treatments in slowing autoimmune retinopathy progression. From the Ophthalmology Science article, "Clinical Outcomes of Therapeutic Interventions for Autoimmune Retinopathy: A Meta-analysis and Systematic Review." Clinical Outcomes of Therap
Ophthalmology Reviews: A New Frontier in the Ophthalmology Family of Journals
Ophthalmology Editor-in-Chief, Russell Van Gelder, MD, PhD, and our new Associate Editor, Laura Downie, BOptom, PhD, guest host this special episode introducing "Ophthalmology Reviews." Ophthalmology Reviews is a new section in our flagship journal for structured systematic reviews and meta-analyses. The two editors discuss the importance of these reviews in our field and what our journal is look
Negative Pressure Goggles Reduce IOP
A revelation while scuba diving leads to a novel device designed to reduce IOP pressure. Dr. Emily Schehlein speaks with Drs. Katherine S. Peters and Daniel Terveen about their study on the FSYX Ocular Pressure Adjusting Pump, from their recent Ophthalmology Glaucoma article, "Manometric Intraocular Pressure Reduction with Negative Pressure Using Ocular Pressure Adjusting Pump Goggles" Manometric
Type 2 Diabetes Medications and Glaucoma Risk
How do GLP-1 receptor agonists and metformin affect glaucoma risk in patients with Type 2 diabetes? Join Dr. Ike Ahmed and Jawad Muayad as they discuss the data on diabetes treatments and glaucoma risk with Dr. Emily Schehlein. From their Ophthalmology article, "Comparative Effects of Glucagon-like Peptide 1 Receptor Agonists and Metformin on Glaucoma Risk in Patients with Type 2 Diabetes." Compar
Blood Pressure and Glaucoma Progression
What is the relationship between blood pressure and visual field progression? Can systemic arterial blood pressure be used to assess the risk of glaucomatous progression? Dr. Emily Schehlein finds out from Dr. David S. Greenfield, author of Ophthalmology's "Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression: The Vascular Imaging in Glaucoma Study." Relationship
Risk of Recurrence in Acute Anterior Uveitis
What are the risk factors and frequency of recurrence in patients with acute anterior uveitis? Dr. Edmund Tsui and Dr. Rachael L. Niederer delve into the findings of her recent Ophthalmology study, "Risk of Recurrence in Acute Anterior Uveitis." Risk of Recurrence in Acute Anterior Uveitis. Brodie, James T. et al. Ophthalmology, Volume 131, Issue 11, 1281 – 1289.
Seasonal Effects on Corneal Immune Cells
People regularly deal with seasonal allergies, but how much do these environmental factors affect our corneas? Dr. Matt Feng sits down with Dr. Laura Downie to discuss her recent Ophthalmology article, "Intravital Imaging of the Human Cornea Reveals the Differential Effects of Season on Innate and Adaptive Immune Cell Morphodynamics." Intravital Imaging of the Human Cornea Reveals the Differential
Peer Review in Ophthalmology and the Council of Vision Editors Fellow Program
Why is peer review important? Is AI changing peer review? How can you become a better peer reviewer? Find out in this special episode, with our newest host and Social Media Editor, Dr. Emily Schehlein, and Dr. Matilda F. Chan. Dr. Chan, in collaboration with editors of several ophthalmic and optometric journals and the National Eye Institute, administers the new Council of Vision Editors Fellow Pr
Plasma Exchange in Optic Neuritis Hospitalizations
Dr. Drew Carey interviews Dr. John J. Chen on the trends and use patterns of plasma exchange therapy for optic neuritis, from his Ophthalmology article, "Trends in Plasma Exchange Use in Optic Neuritis Hospitalizations in the United States." Trends in Plasma Exchange Use in Optic Neuritis Hospitalizations in the United States. Akosman, Sinan et al. Ophthalmology, Volume 131, Issue 10, 1207 – 1214.
cfDNA in Ocular Histiocytosis
Dr. Rajesh Rao speaks with Dr. Jasmine H. Francis on whether sequencing of plasma-derived ctDNA can noninvasively diagnose ocular-involving histiocytosis. From her Ophthalmology Science article, "Plasma-Derived Cell-Free DNA for the Diagnosis of Ocular-Involving Histiocytosis." Plasma-Derived Cell-Free DNA for the Diagnosis of Ocular-Involving Histiocytosis. Francis, Jasmine H. et al. Ophthalmolog
AI for Pediatric Pseudopapilledema and True Papilledema
Can artificial intelligence distinguish between pseudopapilledema and true papilledema in children? Dr. Drew Carey interviews author Dr. Melinda Y. Chang on whether AI can be used to improve the diagnostic process in children with abnormal optic nerves and concern for elevated intracranial pressure. From her Ophthalmology Science article, "Artificial Intelligence to Differentiate Pediatric Pseudop
Evaluating Primary Treatment for People with Advanced Glaucoma
Does primary trabeculectomy or medical treatment produce better outcomes in terms of quality of life, clinical effectiveness, and safety in patients with advanced glaucoma? Dr. Drew Carey interviews Dr. Anthony J. King on the results of his recent study asking this question published in Ophthalmology, "Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatme
Ophthalmology Education in Medical Schools
How has ophthalmology medical education changed over time in medical school curriculums? Dr. Edmund Tsui speaks with Drs. Ashish Agar and Sascha Spencer on their review of global trends in medical school ophthalmology education from their Ophthalmology article, "A Systematic Review of Ophthalmology Education in Medical Schools: The Global Decline." A Systematic Review of Ophthalmology Education in
Adverse Events with Opioids and Ophthalmic Surgery
Ophthalmologists are not spared from the opioid epidemic. Recent studies have shown that opioids continue to be prescribed after ophthalmic surgeries. Dr. Drew Carey interviews Dr. Matthew R. Starr on his retrospective study published in Ophthalmology, "Hospitalization, Overdose, and Mortality After Opioid Prescriptions Tied to Ophthalmic Surgery." Hospitalization, Overdose, and Mortality After Op
CRISPR Assay for Fungal Keratitis
The RID-MyC assay, a CRISPR/Cas12a-based test, offers swift and reliable detection of Fungal Keratitis, enhancing diagnostic capabilities at point-of-care settings. Dr. Rajesh Rao interviews Dr. Siddharth Narendran on the development of this assay from his Ophthalmology Science article, "Development and Clinical Evaluation of a CRISPR/Cas12a-Based Nucleic Acid Detection Platform for the Diagnosis
Bevacizumab in High-Risk Penetrating Keratoplasty
Dr. Matt Feng is joined by Dr. Thomas H. Dohlman to discuss the effectiveness of topical and subconjunctival bevacizumab in suppressing vascularization in graft and host bed after high-risk corneal transplantation, from his Ophthalmology Science article "Suppression of Neovascularization by Topical and Subconjunctival Bevacizumab After High-Risk Corneal Transplantation" Suppression of Neovasculari
Hearing Dysfunction with Teprotumumab
What does hearing dysfunction have to do with an ophthalmology podcast? Listen up and find out as Dr. Drew Carey interviews Dr. Jamie A. Keen and Dr. Erin M. Shriver on the risks of using teprotumumab to hearing function in treatment of thyroid eye disease. From their article "Frequency and Patterns of Hearing Dysfunction in Patients Treated with Teprotumumab." Frequency and Patterns of Hearing Dy
Recurrent Retinal Redetachment after Cataract Surgery
Dr. Matt Feng interviews Drs. Bita Momenaei and Jason Hsu on the incidence, timing, risk factors, and outcomes of recurrent retinal detachment after phacoemulsification, from their Ophthalmology Retina article, "Incidence and Outcomes of Recurrent Retinal Detachment after Cataract Surgery in Eyes with Prior Retinal Detachment Repair." Incidence and Outcomes of Recurrent Retinal Detachment after Ca
Private Equity & Ophthalmology: Spending and Services After Acquisition
Private equity (PE) firms acquired over 200 ophthalmology and optometry practices in the United States from 2021 through 2019. Dr. Rajesh Rao interviews author Dr. Gary Joseph Lelli about the implications of this trend and influence of PEs on care use and spending, from his Ophthalmology article, "Association of Private Equity Firm Acquisition of Ophthalmology Practices with Medicare Spending and
Efficacy of Carbonic Anhydrase in Patients with X-Linked Retinoschisis
X-linked retinoschisis is a relatively common inherited retinal degenerative disease that almost exclusively affects males. No curative medical therapy is available for this condition, however topical and oral carbonic anhydrase inhibitors have been used for the management of cystoid fluid collections. Dr. Drew Carey interviews authors Dr. Jonathan Hensman and Dr. Camiel J.F. Boon on the results
Aqueous Macrophages Contribute to Conserved CCL2 & CXCL10 Gradients in Uveitis
Uveitis is a heterogenous group of inflammatory eye diseases for which current cytokine-targeted immune therapies are effective for only a subset of patients. Dr. Edmund Tsui is joined by Dr. Lynn M. Hassman and MD/PhD student Joseph B. Lin to explore potential common underlying mechanisms that exist for immune cell recruitment in uveitis in their Ophthalmology Science article, "Aqueous macrophage
Vitamin A Deficiency Retinopathy
Vitamin A deficiency is the leading cause of preventable childhood blindness worldwide, but how does this deficiency present itself in a clinical setting? Dr. Drew Carey finds out as he interviews Dr. Nieraj Jain, author of "Characteristics of Vitamin A Deficiency Retinopathy at a Tertiary Referral Center in the United States." Characteristics of Vitamin A Deficiency Retinopathy at a Tertiary Refe
Outcomes and Complications after IOL Exchange
An analysis of the IRIS® Registry shows IOL exchanges are increasing over time with vision improving 60% of the time, but worse visual outcomes associated with greater age, worse baseline vision, Black race, Hispanic ethnicity, Medicaid insurance, smoking, and concurrent vitrectomy. Dr. Matt Feng sits with authors Drs. David F. Chang and Fasika A. Woreta to discuss these findings and more from the
Ophthalmology Workforce Projections, 2020-2035
The Department of Health and Human Services, Health Resources and Services Administration's Health Workforce Simulation Model forecasts a sizeable shortage of ophthalmology supply relative to demand by the year 2035, with substantial geographic disparities. Dr. Edmund Tsui is here with author Dr. Sean T. Berkowitz to breakdown the implications of this shortage from his recent Ophthalmology article
The Effect of Scleral Buckle Surgery on Glaucoma Risk
Scleral buckling is a common surgical procedure for the repair of rhegmatogenous retinal detachment. The association between scleral buckling and angle-closure glaucoma is well-documented. However,the influence of scleral buckling on the development and progression of open-angle glaucoma is less well understood. Dr. Lori Provencher interviews Dr. Arthur J. Sit on the effect of scleral buckle surge
Neuro-Ophthalmology Consultations
Neuro-ophthalmology consultations are critical to the diagnosis and management in the hospital setting. Prompt consultation prevents diagnostic errors and improves patient outcomes. The scarcity of neuro-ophthalmologists means that the increasing outpatient demand cannot be met, prompting many emergency department referrals by non–neuro-ophthalmologists. Dr. Drew Carey discusses this shortage of n
Presentation & Outcomes of Acute Syphilitic Posterior Placoid Chorioretinopathy
Syphilis is often known as the "the great masquerader" because it can mimic symptoms and look like a wide array of other diseases. Dr. Edmund Tsui interviews Dr. Michael Huvard to get to the bottom of how acute syphilitic posterior placoid chorioretinopathy presents itself in eyes and the outcomes for these patients, from his Ophthalmology article "Clinical Characteristics and Visual Outcomes of A
Stem Cell Transplantation and Optic Nerve Regeneration
Dr. Drew Carey sits down with Dr. Thomas V. Johnson to discuss the work of the RReSTORe Consortium in the field of regenerative medicine as applied to optic neuropathies from his Ophthalmology Science article, "The Retinal Ganglion Cell Repopulation, Stem Cell Transplantation, & Optic Nerve Regeneration (RReSTORe) Consortium." For more of the Ophthalmology Science special issue on Neuroprotection,
Cost Drivers of Endothelial Keratoplasty
Endothelial keratoplasty (EK) procedures have become the preferred method of corneal transplantation in the United States. As the frequency of EKs increase, so do associated costs. Dr. Matt Feng interviews Drs. David S. Portney and Shahzad I. Mian about their recent analysis to assess for differences in surgical costs and surgery length based on type of EK, use of preloaded grafts, and performance
Outcomes of Glaucoma Reoperations in the Primary Tube Versus Trabeculectomy
The Primary Tube Versus Trabeculectomy Study is a multicenter randomized clinical trial comparing the safety and efficacy of tube shunt surgery and trabeculectomy with mitomycin C in eyes without previous ocular surgery. Dr. Lori Provencher sits down with authors Dr. Sara J. Coulon and Dr. Steven J. Gedde to discuss the results of this trial from their Ophthalmology Glaucoma article, "Outcomes of
Predictors of Poor Visual Outcome in MOG-related Optic Neuritis
Myelin oligodendrocyte glycoprotein-related optic neuritis is typically associated with good visual outcome in most patients, but poor outcomes are reported in 15% to 36.8% of patients. Dr. Drew Carey sits down with Dr. Edward Margolin to discuss the possible factors associated with poor outcomes, from his Ophthalmology article, "Predictors of Poor Visual Outcome in MOG-related Optic Neuritis." Pr
Live at AAO 2023: Six Myths of the Anterior Segment
Recorded live at AAO 2023 and we're myth busting common ophthalmologic misconceptions of the anterior segment. Drs. Drew Carey and Matt Feng interview Dr. Todd Margolis on his recent Ophthalmology editorial, "Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology." He shares bonus myths not in the editorial, and takes questions from the audience. (Producer's no
Ophthalmologist Turnover in the United States
One-third of US ophthalmologists left at least one practice from 2014-2021. What are the factors behind this high turnover rate, how does this affect patient care, and what can be done to stabilize the workforce? Dr. Rajesh Rao interviews Dr. Ravi Parikh about his Ophthalmology article, "Ophthalmologist Turnover in the United States: Analysis of Workforce Changes from 2014 through 2021." Ophthalmo
MERIT Trial Results: Intravitreal Therapy for Uveitic Macular Edema
What treatments are effective for uveitic macular edema? Drs. Nisha R. Acharya and Douglas A. Jabs of the MUST Research Group discuss with Dr. Edmund Tsui the landmark findings of the MERIT Trial in their recent Ophthalmology article, "Intravitreal Therapy for Uveitic Macular Edema—Ranibizumab versus Methotrexate versus the Dexamethasone Implant." Intravitreal Therapy for Uveitic Macular Edema—Ran
Infections from Artificial Tears
News broke in early 2023 of several deaths related to use of contaminated over-the-counter artificial tear products resulting in FDA and CDC warnings and a product recall. Dr. Matt Feng reviews what transpired and discusses lessons learned with Dr. Gary Novack, author of the Ophthalmology editorial, "Infections from Over-The-Counter Artificial Tears: Implications for Patients and Clinicians." Infe
Risk of Pseudophakic Cystoid Macular Edema in Cataract Surgeries
Cataract surgery is one of the most commonly performed surgeries globally. What are the risk factors for patients developing pseudophakic cystoid macular edema after cataract surgery? Dr. Edmund Tsui sits down with Dr. Ahmed B. Sallam to discuss the findings of his Ophthalmology article, "Risk of Pseudophakic Cystoid Macular Edema in Fellow-Eye Cataract Surgeries: A Multicenter Database Study." Ri
Reduced Cone Density in Multiple Sclerosis
Does multiple sclerosis contribute to the degeneration of the outer retinal layers? Dr. Drew Carey interviews Dr. Imre Lengyel on his recent Ophthalmology Science article, "Reduced Cone Density Is Associated with Multiple Sclerosis." Reduced Cone Density Is Associated with Multiple Sclerosis. McIlwaine, Gemma et al. Ophthalmology Science, Volume 3, Issue 3, 100308 Sign up for the next Ophthalmolog
A Review of RCT Ophthalmic Papers 2020-2021
How can we improve the design and reporting of ophthalmic randomized controlled trials? Dr. Edmund Tsui discusses this with Dr. Gui-shuang Ying author of Ophthalmology Science's "Characteristics of Design and Analysis of Ophthalmic Randomized Controlled Trials." Characteristics of Design and Analysis of Ophthalmic Randomized Controlled Trials. Dong, Ruiqi et al. Ophthalmology Science, Volume 3, Is
Performance of ChatGPT in Ophthalmology
Can ChatGPT pass the OKAP exam? Dr. Matt Feng interviews author Dr. Fares Antaki about the implications of using a language model artificial intelligence in ophthalmology from his Ophthalmology Science article, "Evaluating the Performance of ChatGPT in Ophthalmology: An Analysis of Its Successes and Shortcomings" Evaluating the Performance of ChatGPT in Ophthalmology. Antaki, Fares et al. Ophthalm
Central Retinal Artery Occlusion: Time to Presentation & Diagnosis
Is an eye stroke (CRAO) the same as a brain stroke? What new treatments are available for eye stroke? Dr. Drew Carey sits down with Drs. Aubrey Gilbert and Robin Vora to discuss their Ophthalmology Retina article, Central Retinal Artery Occlusion: Time to Presentation and Diagnosis. Central Retinal Artery Occlusion. Shah, Ronak et al. Ophthalmology Retina, Volume 7, Issue 6, 527 - 531 Sign up fo
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