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Health Optimization Medicine Podcast

Health Optimization Medicine Podcast

Health Optimization Medicine and Practice 180 Episodes Aug 19, 2026

The Health Optimization Medicine Podcast explores health optimization, decision-making, consciousness, performance, and human potential through conversations with leading researchers and clinicians. Produced by Health Optimization Medicine & Practice and Smarter Not Harder, Inc., it bridges rigorous science with real-world clinical application. Hosted by Dr. Ted Achacoso, Dr. Scott Sherr, Boomer Anderson, and Jodi Duval, the show features guests like Karl Friston and Donald Hoffman. New episodes are released every Wednesday.

Episodes

The Real Cause of Endotoxemia: Leaky Gut Explained | HOMe #23
The Real Cause of Endotoxemia: Leaky Gut Explained | HOMe #23 Aug 19, 2026 15:08 In this episode of the Health Optimization Medicine Podcast, Boomer Anderson, Dr. Allen Bookatz, Dr. Ted Achacoso, and Dr. Jup Kuipers explore a misunderstood cause of chronic fatigue and leaky gut: the bioenergetic failure of your colonocytes. While many practitioners throw random probiotic strains and anti-inflammatory herbs at gut issues, metabolomic research shows this approach fails to addres
Is Your Cellular Membrane Leaking the Fuel That Keeps You Going? (Why NAD+ Isn't Enough) | HOMe #022
Is Your Cellular Membrane Leaking the Fuel That Keeps You Going? (Why NAD+ Isn't Enough) | HOMe #022 Aug 12, 2026 23:39 In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Allen Bookatz, and Jodi Duval explore one of the most overlooked causes of declining cellular energy: the structural breakdown of the mitochondrial membrane. While many people invest in premium longevity supplements like NAD+, NMN, and CoQ10 to improve energy production, emerging research suggests t
Dr. Dominic D'Agostino Explains What Ketones Actually Do to Your Body | HOMe Podcast #021
Dr. Dominic D'Agostino Explains What Ketones Actually Do to Your Body | HOMe Podcast #021 Aug 5, 2026 52:39 In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr sits down with Dr. Dominic D'Agostino, the premier researcher in ketogenic metabolic therapies. Moving past the mainstream fads of keto ice cream and internet trends, they break down how exogenous ketones actually impact cellular energy, cardiovascular health, and environmental stress. From the liver toxicity associated w
Metformin is Poisoning Your Cells | HOMe Podcast #020
Metformin is Poisoning Your Cells | HOMe Podcast #020 Aug 3, 2026 18:47 In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Scott Sherr, Dr. Allen Bookatz, Jodi Duval, and Dr. Jup Kuipers take a deep dive into the shocking new 21-year pre-diabetes follow-up study (DPPOS) published in the Journal of the American Medical Association on June 15, 2026. Moving past the mainstream longevity hype surrounding Metformin as an anti-aging cure-all,
The Gut-Brain-Microbiome Axis: Understanding Depression, Serotonin, & Probiotics | HOMe Podcast #019
The Gut-Brain-Microbiome Axis: Understanding Depression, Serotonin, & Probiotics | HOMe Podcast #019 Jul 22, 2026 32:18 In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Scott Sherr, Dr. Allen Bookatz, Dr. Jup Kuipers, and Jodi Duval take a deep dive into the gut-brain-microbiota axis. Moving past the simplistic, pathogenic "pill-for-an-ill" approach of conventional psychiatry and the mainstream hype around over-the-counter probiotics, the faculty breaks down why establishing enteri
Why You Can't Out-Supplement a Dysregulated Nervous System | HOMe Podcast #018
Why You Can't Out-Supplement a Dysregulated Nervous System | HOMe Podcast #018 Jul 15, 2026 26:38 In this episode of the Health Optimization Medicine Podcast, Dr. Allen Bookatz, Dr. Ted Achacoso, and Jodi Duval tackle the widespread trend of supplement fatigue. As biohacking becomes a mindset of treating symptoms with heavy stimulants and endless pills, the faculty breaks down why forcing adaptation on an exhausted system only drives the body deeper into a chronic state of inflammatory defense
Cellular Safety and the Dangers of Mechanical Blood Microplastic Detox | HOMe Podcast #017
Cellular Safety and the Dangers of Mechanical Blood Microplastic Detox | HOMe Podcast #017 Jul 8, 2026 21:26 In this episode of the Health Optimization Medicine Podcast, our faculty, Dr. Scott Sherr, Dr. Ted Achacoso, Boomer Anderson, Dr. Allen Bookatz, and Jodi Duval, tackle the recent trend of therapeutic plasma exchange and "blood washing". Moving past the mainstream marketing of plasmapheresis as a longevity cure-all, the team breaks down why mechanical filtering is only a surface-level fix for micro
The HRV Paradox: Why Tracking Your Sleep Makes It Worse | HOMe Podcast #016
The HRV Paradox: Why Tracking Your Sleep Makes It Worse | HOMe Podcast #016 Jul 1, 2026 21:16 In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe faculty (Dr. Scott Sherr, Dr. Ted Achacoso, Boomer Anderson, and Jodi Duval) tackles one of the most paradoxical trends in modern biohacking: sleep tracking. Moving past the mainstream obsession with daily device scores, the team breaks down the biochemical realities of how tracking your HRV might actually be sabotaging your
Decoding the Holobiont: The Ecosystem of Ecosystems | HOMe Podcast Special Episode
Decoding the Holobiont: The Ecosystem of Ecosystems | HOMe Podcast Special Episode Jun 24, 2026 15:28 In this special in-person roundtable recorded in Washington, D.C., the HOMeHOPe faculty sit down to decode one of the most important perspective shifts in modern health: the Holobiont. Moving away from the traditional, siloed medical model of "organology" (treating the heart, gut, and brain as isolated systems managed by different specialists), the faculty discusses why true health optimization re
Bypass the Fiber Trend & Optimize Your Gut Health | HOMe Podcast #015
Bypass the Fiber Trend & Optimize Your Gut Health | HOMe Podcast #015 Jun 17, 2026 15:28 In this episode of the Health Optimization Medicine Podcast, the core faculty (Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz) tackles one of the most misunderstood topics in modern nutrition: fiber. Moving past the mainstream trend of "fiber-maxing," the team breaks down the actual biochemical realities of how different forms of fiber interact with your unique gut micro
Why Aging May Be the Root Cause of Chronic Disease | HOMe Podcast #014
Why Aging May Be the Root Cause of Chronic Disease | HOMe Podcast #014 Jun 10, 2026 13:44 In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe faculty, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz reunite in person in Washington, D.C.. Moving away from traditional classifications of illness, the team breaks down a powerful paradigm shift: chronic disease and aging are not separate processes—chronic disease is aging. Drawing from the pio
Health Optimization for Parenting, Pregnancy & Family Life | HOMe Podcast #013
Health Optimization for Parenting, Pregnancy & Family Life | HOMe Podcast #013 Jun 3, 2026 24:37 In this episode of the Health Optimization Medicine Podcast, hosts Dr. Scott Sherr and Jodi Duval come together for an intimate, parent-to-parent roundtable. As the only current parents on the HOMeHOPe faculty, they dive deep into the specific biology of preconception, pregnancy, and pediatric health optimization. Moving beyond typical disease management, they explore how to foster both psychologi

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