Fat Science
Fat Science is a podcast that explores the science behind body fat, explaining why it accumulates and why it's difficult to lose. Each episode shares little-known facts and personal stories to dispel misconceptions, reduce stigma, and instill hope. The podcast aims to empower listeners with accurate information about metabolism and promote understanding that fat is not a failure.
Episodes
Plastic Chemicals in Your Blood and What Actually Works to Remove Them
Have you ever wondered why your body holds onto weight despite your best efforts?In this eye-opening episode, Dr. Cooper reveals groundbreaking research showing that 100% of healthy adults carry at least six different plastic-related chemicals in their bodies daily. These endocrine disruptors don't just affect your hormones - they may be stored in your fat tissue and could be a hidden driver o
Why Weight Loss Stalls on GLP-1s — Even When You’re Doing Everything “Right
What happens when GLP-1 medications stop working the way you hoped they would? In this mailbag episode, Dr. Emily Cooper answers listener questions about fasting, insulin levels, PCOS, lipedema, plateaus on Zepbound, and the complicated reality behind metabolic dysfunction. From the dangers of under-fueling to why individualized treatment matters so much, this conversation unpacks the science behi
Normal Weight Abnormal Metabolism: Why Your Scale Doesn't Tell the Whole Story
Could you have metabolic dysfunction even at a normal weight?This episode challenges everything we've been taught about weight and health. Dr. Cooper reveals that up to 25% of normal-weight people have metabolic syndrome, yet they're rarely screened because doctors assume they're healthy based on appearance alone.KEY TAKEAWAYSWeight and metabolic health are not the same thing - you can
Mailbag: Why GLP-1 Medications Sometimes Stop Working
Have you been told your metabolism is broken and there's nothing you can do about it?This mailbag episode tackles tough questions about medication effectiveness, unexpected side effects, and the complex realities of treating metabolic dysfunction. Dr. Cooper addresses why some people regain weight while still on GLP-1s, explores the connection between hair loss and weight loss medications, and
Why Three Major Obesity Organizations Just Changed What Success Means
Ever wonder why you can improve your health but still feel like you're failing because the scale isn't cooperating?Dr. Cooper breaks down groundbreaking new clinical guidelines from three major obesity organizations that are completely reframing what success in obesity treatment actually means. For the first time, these groups are saying quality of life, energy levels, and overall health m
PCOS is Now PMOS: The Name Change That Changes Everything
Have you been told you have PCOS but nothing seems to help?In May 2024, after 14 years of global collaboration involving 56 organizations and 22,000 stakeholders, the medical community officially changed PCOS to PMOS - and the reason why reveals everything that's been wrong with how this condition has been understood and treated for decades. Dr. Cooper breaks down why this isn't just a nam
Mailbag - Why Your Doctor Still Believes Calories In Calories Out
Have you been told it's just calories in calories out while your lived experience says otherwise?In this mailbag episode, Dr. Cooper addresses complex metabolic questions from listeners worldwide. From eating disorders requiring specialized care to GLP-1 plateau management, each question reveals how individual biology trumps one-size-fits-all solutions.KEY TAKEAWAYSEating disorders like anorex
What Lipedema Really Is and Why Your Doctor Might Be Missing It
Are your legs painful to touch and resistant to weight loss despite your best efforts?Dr. Ellen Derrick, a vascular surgeon and lipedema specialist, reveals the truth about this misunderstood condition affecting 20% of women worldwide. Lipedema isn't obesity - it's a fat cell disorder where tissue responds abnormally to inflammation, creating painful, swollen areas that don't respond t
Metabolic Breaking News: 3 Developments You Should Know About
Dr. Emily Cooper, Mark Wright, and Andrea Taylor break down three breaking metabolic health stories in this quick bonus episode — from a newly approved oral GLP-1 to a major price drop for Medicare patients.Links & ResourcesPodcast Home: fatsciencepodcast.comCooper Center for Metabolism: coopermetabolic.comResources from Dr. Cooper: coopermetabolic.com/resourcesJoin Our Community: patreon.com/
Mailbag: Mechanical Eating vs Calorie Counting on Ozempic and Wegovy
Have you ever wondered if you should get liposuction when you need skin removal surgery after major weight loss?In this mailbag episode, Dr. Cooper, Mark, and Andrea tackle questions from listeners around the world, from Germany to Alabama to Chicago. They discuss why restricting calories while on GLP-1 medications can actually work against you, address the reality of finding metabolic-informed do
Top 10 GLP-1 Myths Debunked by Science
Ever hear someone say GLP-1 medications cause osteoporosis or make your hair fall out?This episode tackles the top 10 biggest myths about GLP-1 medications flooding social media and separates the science from the scary headlines. Dr. Cooper breaks down what's actually happening in your body versus what the internet claims, from bone density concerns to the dreaded "Ozempic face."KEY
New Obesity Drugs: What's FDA Approved and What's Coming
The obesity medication landscape just changed — again. One brand-new pill is already in pharmacies, and five more are in various stages of approval. But the real story isn't the drugs themselves: it's what they're revealing about how your metabolism actually works, and why willpower was never the problem.This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor break d
Mailbag: Understanding Insulin Resistance Testing and GLP-1 Medication Side Effects
Have you been told insulin resistance testing doesn't exist or wondered if you're increasing your GLP-1 dose too quickly?Dr. Cooper, Andrea, and Mark tackle listener questions from around the world, addressing common concerns about insulin resistance testing availability, managing severe GI side effects from higher doses, interpreting DEXA scan results, and developing sustainable maintenan
Navigating the GLP-1 Wild West: A Conversation With Dr. Vin Gupta
Are you getting a GLP-1 prescription from someone who's never examined you?Dr. Vin Gupta, pulmonologist and former Chief Medical Officer at Amazon, joins Dr. Cooper to expose the dangerous gap between legitimate obesity medicine and the unregulated direct-to-consumer market. This conversation reveals why proper medical evaluation matters and how profit-driven platforms are exploiting desperate
What Happens to Your Body When You Stop Taking GLP-1s
What really happens when you stop GLP-1 medications — and are the headlines telling you the whole story? The answer is more nuanced than social media wants you to believe.This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor break down four recent studies on GLP-1 treatment outcomes, weight regain, and a groundbreaking new drug that could preserve lean mass during treatment. T
Mailbag: Fasting, Food Noise & GLP-1s
Ever wonder why fasting worked at first — then stopped? Or why you lost 80 pounds only to gain back 100?In this mailbag episode, Dr. Emily Cooper, Mark Wright, and Andrea Taylor tackle the most misunderstood topics in metabolic health. From the harsh reality of fasting culture to the surprising metabolic challenges faced by normal-weight individuals, this conversation validates what you've bee
Why You Keep Waking Up at Night — What 15,000 Patient Encounters Reveal About Sleep and Metabolism
Are you getting eight hours in bed but still waking up exhausted?Dr. Emily Cooper shares groundbreaking findings from nearly 15,000 patient encounters at her metabolic clinic. The data reveals surprising connections between stress, eating frequency, sleep quality, and metabolic health — and why the number of hours you spend in bed doesn't tell the whole story.KEY TAKEAWAYSOver 60% of patients
Mailbag: Your GLP-1 Questions: Hair Loss, Blood Sugar Spikes & Hormone Therapy
Think squashing your post-meal glucose spike is the healthy thing to do? What if that flat line on your CGM is actually telling your brain you didn't eat — and slowing your metabolism as a result?This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor open the mailbag to tackle listener questions from around the world — Australia, New Zealand, and across the U.S. They dig in
Why GLP-1s Alone May Not Be Enough: A Listener's Real Story
What happens when you do everything "right" — the GLP-1, the protein shake, the tracking — and the scale still won't budge? This episode reveals why doing everything “right” might actually be a big part of the problem.This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor welcome Sandy, a listener from Pennsylvania who has been on the metabolic health journey for
The Science Behind the New Wegovy Pill: One-On-One with Novo Nordisk’s Dr. Jason Brett.
The Science Behind the New Wegovy Pill (with Novo Nordisk’s Dr. Jason Brett)What actually makes a GLP-1 pill work in the real world—and why does taking it come with such specific rules? And if these meds improve health beyond weight, why does the conversation still get stuck on the scale?This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor are joined by Dr. Jason Brett of Nov
Mailbag: Your GLP-1 Questions on Pregnancy, Dosing, and Why Diets Cause Fat Gain
Mailbag: Your GLP-1 Questions on Pregnancy, Dosing, and Why Diets Cause Fat GainWhat happens when you stop GLP-1 medications before getting pregnant? Why might your thyroid numbers change on Zepbound? And why do people gain more body fat after dieting — even when they're still eating well? Dr. Cooper tackles your toughest questions.This week on Fat Science, Dr. Emily Cooper, Mark Wright, and A
Wegovy Pill vs. Injection — A Doctor Breaks Down the Newest Form of GLP-1
Wegovy Pill: Who's It For?The new Wegovy pill is generating massive buzz — but is it actually better than the injection? Before you ask your doctor to switch, there are some surprising requirements that could make or break whether this option works for you.This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor break down the new oral semaglutide approved for obesity treatme
Why GLP-1 Medications Work Even When the Scale Doesn't Move
What if the scale isn't moving, but your health is dramatically improving?If you've ever felt discouraged because the number on the scale won't budge—even on a GLP-1 medication—this episode will change how you think about these drugs. Dr. Cooper breaks down the research showing that the biggest benefits have nothing to do with weight loss. It's all about metabolic health.This Week
Mailbag: Food Tracking, Mechanical Eating Troubleshooting, COVID & Metabolism, and Metformin + GLP-1 Synergy
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor answer listener mailbag questions from California, the UK, France, Washington, Wyoming, and beyond. The team breaks down why Dr. Cooper does not recommend calorie tracking (and when limited tracking can make sense), how to build confidence in eating without data, and why “mechanical eating” sometimes needs medical customiza
Mailbag: GLP-1 Weight Regain, Meals vs Snacks, and Why Some People Don’t Respond
his week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor answer listener mailbag questions that get to the heart of metabolic health. The team explains the real difference between meals and snacks, discusses whether GLP-1 medications can be appropriate for children in complex cases, explores why some people appear to be “non-responders” to Wegovy, and breaks down why alarming head
What the Headlines Get Wrong About GLP-1 Drugs and Metabolism
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor break down two GLP-1 studies that challenge a major media myth: GLP-1 medications don’t drive weight loss just because people eat less. Instead, drugs like tirzepatide and semaglutide create direct metabolic shifts—including increased fat oxidation and improved fuel partitioning—regardless of appetite.The team also explores
GLP-1 Mailbag: Weight Regain, Leptin Resistance, Hypoglycemia & Why Calories Aren’t the Problem
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor tackle a wide-ranging mailbag episode with listener questions from the U.S., UK, and Europe. Topics include unexpected weight regain on GLP-1s, post-meal sleepiness and hypoglycemia, metabolic dysfunction despite normal labs, GLP-1 dosing strategies, and why these medications are about metabolism, not appetite suppression.K
Childhood Obesity, Eating Disorders & GLP-1s: Why It’s Not Your Fault
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor talk with pediatric eating disorder specialist Dr. Julie O’Toole (Kartini Clinic) and pediatric obesity expert Dr. Evan Nadler about what childhood obesity really is: a biologic, metabolic disease—not a willpower problem and not a failure of parenting.They explore how excess weight, constant hunger, and disordered eating in
I’m Working Out—So Why Am I Getting Fatter?
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor talk with exercise physiologist Russell Cunningham and patient Becca Wert about a counterintuitive reality: for some people, exercise can actually slow metabolism, stall weight loss, and trigger weight gain—especially when the brain senses a threat to energy availability. Dr. Cooper explains how overtraining, under-fueling,
The Latest GLP-1 News
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor unpack the biggest GLP-1 headlines from around the world—from the World Health Organization’s first-ever GLP-1 obesity guidelines to access battles, brain research, and the coming wave of generics and new meds.Dr. Cooper explains what the WHO’s move really means for patients, why long-term treatment matters, and how policy
Listener Mailbag: Set Point Theory, Trauma & Metabolism, and Why 1200 Calories Can Still Lead to Weight Gain
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor answer listener questions about BMI cutoffs, weight cycling, metabolic adaptation, trauma, GLP-1 differences, and why some people gain weight on ultra-low calories. Dr. Cooper explains what’s really happening inside the metabolic system and why individualized treatment—not dieting—creates sustainable change.Key Questions An
A Patient’s Guide to Taking Back Your Health
Dr. Emily Cooper, Mark Wright, and Andrea Taylor talk with Maria from Buffalo, a longtime listener who shares her lifelong journey with obesity, psoriatic arthritis, and binge eating—and how finally understanding the science of metabolism gave her hope. Maria describes early childhood weight gain, joint damage, and years of restrictive dieting and food shame, then explains how GLP‑1 therapy (Zepbo
Listener Mailbag – Practical Metabolic Care, GLP‑1 Myths, and the Dangers of Microdosing
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor field your most urgent metabolic health questions—exploring care advocacy, novel drug use, lab results, and how to filter fact from fiction in the TikTok age. Dr. Cooper offers clinical clarity, real-world perspective, and actionable hope—with an emphasis on what truly matters for your long-term health and energy.Hear from
Listener Mailbag – Metabolic Mysteries, Medication Strategies, and Dr. Cooper’s Science-Based Answers
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor dive into your burning questions from around the world—exploring misunderstood metabolic problems, hard-won solutions for real people, and the science behind the headlines. From “selfish brain” physiology to the rollercoaster of insurance and medication access, Dr. Cooper brings clinical clarity and practical hope.Hear real
From Voodoo to Mainstream: Debunking Diet Culture in the Age of GLP-1s
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor take a trip to the past when Dr. Cooper didn’t have many supporters in medicine. She shares what it was like to be ridiculed by her peers, why she refused to give up on her patients, and how her science-based approach to metabolism was finally validated by mainstream medicine.Hear the raw, unfiltered story of resilience, pa
Mailbag: Low Blood Sugar Explained, Relief From Food Noise, Calorie Restriction Warning, Metabolic Health care on a Budget, and More.
his week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor tackle the biggest listener questions about sustainable weight loss, metabolic health, and why restrictive diets so often backfire. From medications like GLP-1s to common myths about exercise and nutrition, this episode delivers practical science and down-to-earth advice for anyone struggling with their weight and/or health.
New Blood Pressure Guidelines: What You Need to Know
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor dive into the latest U.S. blood pressure guidelines—and reveal why nearly half of all Americans face risks that can no longer be ignored. Early intervention and smart lifestyle changes are at the heart of these new recommendations.Why is high blood pressure such a hidden danger? What do the new “elevated” and “stage one” ca
The Mailbag: GLP‑1s, Leptin, Hormones & Insurance Advice
Fat Science Ep 106The Mailbag: GLP 1s, Leptin, Hormones & Insurance AdviceThis week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor open the listener mailbag to answer real questions from around the world about metabolism, hormones, and GLP-1 therapy. From the UK to Seattle, listeners share personal stories of confusion and discovery — and Dr. Cooper brings metabolic science b
The Fallacy of GLP-1 “Diets” & the Microdosing Ad Frenzy
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright take on one of the biggest misinformation waves in popular health media: the rise of “microdosed” GLP‑1s and so‑called “GLP‑1 diets.” As GLP‑1 medications dominate headlines and social media feeds, the hosts cut through the noise to explain what’s actually safe, what’s marketing hype, and why restrictive diets go against me
Childhood Obesity: Science, Shame & New Hope
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor are joined by renowned childhood obesity expert Dr. Evan Nadler for a deep, honest conversation about what really is making our kids fat—and what’s finally changing about how kids, parents, and doctors can fight it.The panel unpacks why the word “fat” is still so emotionally charged, how culture and even healthcare still ge
How Microdosing Can Backfire
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright take a hard look at the buzz around microdosing metabolic medications—from what “microdosing” actually means to the risks of following trends without clinical supervision. The team unpacks widespread misunderstandings about dosing for drugs like Ozempic, Zepbound, and low-dose naltrexone (LDN), explains why social media advi
5 Surprising Metabolic Studies From 2025
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright break down five eye-opening research studies from 2025 that challenge everything you thought you knew about obesity, dieting, and metabolism. The hosts explore surprising new evidence on fitness trackers, the metabolic power of joy (and dessert!), the risks of intermittent fasting, how yo-yo dieting can damage kidney health
Centuries of Evidence: Why Diets Don’t Work
This week on Fat Science, Mark Wright, Andrea Taylor, and Dr. Emily Cooper dig deep into the science and history behind why diets don’t work for lasting weight management. From early fad diets, through to modern metabolic research, the episode explains why calorie restriction often backfires—and why fueling the body is key to long-term health.Dr. Cooper unpacks the latest evidence about metabolic
Fat Science Live: Celebrating Our 100th Episode!
The 100th episode of Fat Science brings together Dr. Emily Cooper, Andrea Taylor, and Mark Wright for a live mailbag celebration with listeners worldwide. Hear how the show began, reflect on lessons learned, and get answers to the questions people wish their doctors would address—especially about metabolism, obesity, diabetes, GLP-1 medications, and more.Dr. Cooper shares the big-picture science b
Eating Your Way to Normal
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright explore the dangers of under-fueling and challenge dieting myths with guest Gina Davito. This episode dives into Gina’s journey from extreme restriction and over-exercising to finally achieving metabolic balance and freedom from food obsession. Dr. Cooper sheds light on the science behind metabolic adaptation, appetite regu
Mailbag: GLP-1s, Liver Health, Mechanical Eating & Metabolic Truths
This week on Fat Science we answer your questions in another, always-popular mailbag episode. Join Mark Wright, Andrea Taylor, and Dr. Emily Cooper and learn why some people don’t respond to GLP-1 medications, get the latest on new, oral weight-loss drugs, and explore the science behind elevated liver enzymes. Dr. Cooper offers practical insights backed by metabolic research. She also addresses gl
Muscle, Metabolism, and Mentality: Lessons from an 82-Year-Old Powerlifter
Join Dr. Emily Cooper, Andrea Taylor, and Mark Wright on Fat Science as they dive into the power of strength training—not just for elite athletes, but for everyday health and longevity.This week’s guests bring unique perspectives: Faith Ireland, retired Washington State Supreme Court Justice and 82-year-old world-record-holding powerlifter, and Russell Cunningham, MA, CRC, exercise physiologist wh
The Stress Hormone Cortisol: Friend or Enemy?
Join Dr. Emily Cooper, Andrea Taylor, and Mark Wright on Fat Science as they unravel the complex role of cortisol, the body’s primary stress hormone. Dr. Cooper explains how cortisol isn’t always bad—it helps us adapt to stress, mobilize energy, and even save our lives in emergencies, but chronic elevation can cause serious health problems like insomnia, weight gain, and increased risk for diabete
How Parental Perception Shapes Kids’ Bodies
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright explore the surprising influence of parental perception on children’s weight and metabolic health. Dr. Cooper breaks down the science connecting how parents think and talk about body size to the way their kids develop physically and emotionally. The episode tackles the real-world consequences of parental concerns, dieting m
Fat Science Mailbag: The Dangers of Restricting Calories, Bariatric Plateaus, GLP-1 Dose Adjustments, Weight Expectations & More
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright open the Fat Science mailbag to answer listener questions from around the globe. This episode covers real-world metabolic challenges—from navigating calorie restriction and GLP-1 medications to the complexities of bariatric surgery, prednisone’s impact on weight, and menopause. Dr. Cooper offers clear explanations and pract
Metabolic Drugs: Why One Size Doesn’t Fit All
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright unpack the latest breakthroughs in metabolic medications and why individual biology requires personalized treatment. Dr. Cooper explains how modern therapies for metabolic dysfunction go far beyond the old “one pill fixes all” approach. Discover how hormone-based medications like GLP-1 agonists are changing obesity and diab
Endocrine Disruptors: Hidden Chemicals and Metabolic Health
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright revisit the critical topic of endocrine disruptors—chemicals in our environment that interfere with hormones and impact metabolism, weight, and overall health. Dr. Cooper breaks down how everyday exposures to substances like phthalates, BPA, and others can have generational effects on metabolic pathways and disease risk. Th
Profits vs. Prevention: How Do We Fix Healthcare?
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright tackle the frustrations of navigating the American healthcare system—especially when it comes to treating metabolic dysfunction, diabetes, and obesity. Mark vents about insurance obstacles, while Dr. Cooper breaks down how short-term thinking, excessive profit layers and lack of preventive care put patient health at risk. A
Metabolic Workup 101: What Tests Reveal About Your Health
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright break down the essentials of a true metabolic workup. This episode moves beyond social media diet trends and digs into the science behind comprehensive lab panels, what they measure, and why they matter for your whole-body health. Dr. Cooper explains how to interpret common and advanced metabolic markers—like blood sugar, i
Fatty Liver Disease: What You Need to Know
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright uncover the truth about fatty liver disease and its rapid rise in both adults and children. It’s estimated 125 million Americans have the disease. Dr. Cooper explains the critical role the liver plays in metabolism—covering hundreds of essential functions—and why fatty infiltration poses serious risks. The episode demystifi
Is Male Menopause Real?
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright explore the concept of “male menopause” and whether it’s backed by science. Dr. Cooper breaks down hormonal changes in men, including testosterone decline, metabolic dysfunction, and the myths surrounding andropause. The episode dives into why men and women experience aging differently, how metabolism ties into hormone shif
The Rise of Metabolic Telehealth
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright explore the expanding world of telehealth in treating metabolic issues. Dr. Cooper sheds light on both the promise and pitfalls of accessing medications like GLP-1s through online platforms. The episode dives into the effectiveness of patient-provider relationships, the importance of comprehensive and personalized care, and
Mailbag: Metabolism Myths, Plateaus, and More
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright answer listener questions from around the world about metabolic health. This mailbag episode explores widely-debated topics like “starvation mode,” weight loss plateaus, the relationship between metabolism and cognitive health, cannabis and metabolism, metabolic effects of liposuction, and the latest on GLP-1 medications.Ke
Why Sometimes It Takes a Little Patience
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright explore why metabolic health transformations require time, persistence, and a holistic approach. Andrea shares her 14-year journey with Dr. Cooper, highlighting the slow, individualized nature of healing a dysfunctional metabolism and why quick fixes rarely work. Dr. Cooper explains how complex feedback loops, hormonal adap
GLP-1s: Will I Have to Take Them Forever?
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright break down the latest science behind GLP-1 medications like Ozempic, Wegovy, and Mounjaro. Dr. Cooper shares her decades of expertise on how these drugs work, their evolution, and whether you really have to take them for life. The episode dives deep into the individual factors that impact tapering off, the importance of met
Dosing Download: How much? When? Is It Working?
Join Dr. Emily Cooper, Andrea Taylor, and Mark Wright on Fat Science as they unpack the complexities of dosing GLP-1 medications for metabolic health and weight management. Dr. Cooper emphasizes the importance of an individualized approach, debunking the myth that higher doses or faster titration always lead to better outcomes. The team addresses listener questions about how and when to increase d
Mailbag: Your Questions Answered
Join Dr. Emily Cooper, Andrea Taylor, and Mark Wright on Fat Science for a special mailbag episode answering listener questions about metabolic health. Dr. Cooper explains the difference between mindful and mechanical (timed) eating, especially for those using medications like Zepbound. The team also addresses emotional challenges tied to frequent eating, societal fat shaming, and the complexities
Starved For Answers: The Fallout of Federal Science Cuts
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright tackle the urgent issue of deep funding cuts to scientific research in the United States. Dr. Cooper shares firsthand insight on how these changes are affecting patient care and scientific integrity, highlighting the pressures researchers face—including censorship and loss of resources at institutions like the NIH. The conve
Blood Fats: The Good, the Bad & the Ugly
This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright dive into the world of blood fats—unpacking what cholesterol numbers really mean for your health. They break down HDL (the “good” cholesterol), LDL (the “bad” cholesterol), triglycerides, and spotlight the often-overlooked lipoprotein(a), a genetic risk marker with significant consequences for heart health. The team dispels
Diabetes Wake-Up Call: The Silent Epidemic
Diabetes Wake-Up Call: The Silent EpidemicIn this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright take on a troubling statistic—half of American adults are either diabetic or prediabetic, and for those with prediabetes, 8 in 10 don’t know it. Think about your own family. The odds are one in two of your loved ones are at risk.The good news is diagnosing diabetes is easy, and
Understanding Metabolic Health: Top Ten Strategies (Part 2)
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright continue exploring the top ten positive things you can do for your metabolism, focusing on steps five through one. With an honest and approachable discussion, this episode sheds light on essential topics like endocrine disruptors, nutrition, sleep, body image, and why the focus should be on health, not weight. Get prac
Understanding Metabolic Health: Top Ten Strategies (Part 1)
n this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright break down their top ten lifestyle strategies to enhance your metabolic health. They critically discuss powerful yet straightforward approaches that can significantly improve metabolism. The focus is on easy-to-implement, applicable tips, from knowing key health numbers to managing stress effectively.Key Takeaways:Know
The People Side of Metabolic Medicine
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore the human connections in metabolic medicine. With special guest Alisha, a nurse practitioner at the Cooper Center for Metabolism, the episode delves into how patient-provider relationships have a profound impact on metabolic health outcomes. If you're interested in how the world of metabolic medicine is evo
Listener Spotlight
On this episode of Fat Science, it’s time to hear from some of you, our listeners. Dr. Emily Cooper, Andrea Taylor and Mark Wright are joined by two loyal listeners, Scott and Heidi. The episode explores personal anecdotes and transformative moments thanks to a deeper understanding of metabolic health and its broader implications. It also shows you don’t have to have Metabolic Syndrome to benefit
Compounded Drugs Part 2
On this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright delve deeper into the topic of compounded metabolic drugs. Dr. Cooper addresses criticisms from listeners about the previous discussion and provides insights into the economic reasons driving people towards compounded drugs. She also dissects the ethics and economics of the diet industry transforming into a subscriptio
More Mailbag
On this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright open the mailbag and answer questions from listeners all over the world.Dr. Cooper provides expert insights into complex questions about metabolic health, covering topics including metabolic dysfunction, the effects of chemotherapy on metabolism, a discussion of GLP-1s and those trying to get pregnant and the role of i
The Metabolic Links to PCOS
On this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore the intricate metabolic ties to Polycystic Ovarian Syndrome (PCOS). Dr. Cooper provides expert insight into how understanding these links can transform what seems like a permanent condition into a reversible one. “ I feel like there's so much despair around PCOS when it actually doesn't have to be a lon
Letting Go of Calories-In, Calories-Out
On this episode of Fat Science, it’s time to let go of the old paradigm “calories in, calories out.” Join hosts Dr. Emily Cooper, Andrea Taylor and Mark Wright as they kick CICO to the curb. The idea that a person’s weight is determined only by the ratio of calories consumed and calories burned is an over-simplification and often not true, especially for people with metabolic dysfunction. Dr. Coop
Straight Talk on Compounded Drugs
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore the world of compounded drugs. These are medications prepared by pharmacists to meet specific needs of patients when commercially-available products are not an option. Changes in dose, accommodating patients with allergies or sensitivities and drug shortages are some of the reasons the FDA allows compounded dru
Cravings: Culprit or Symptom.
n this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore cravings and the role they play in metabolic dysfunction.
If you watch some drug company commercials these days, you’d think cravings are the culprit for obesity. In reality, they are just a symptom of a deeper metabolic problem.
This episode of Fat Science uncovers why this oversimplification is not just misle
Who Are We Calling Fat?
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore one of the most contentious topics in the world of health and fitness: the definition and measurement of fat.
BMI (Body Mass Index) has long been the standard, but recent studies have called its efficacy into question.
Dr. Cooper reveals why BMI can be a flawed indicator of health, exploring alternate measurem
Get Healthy in 2025 With These 5 Resolutions
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore five New Year’s resolutions you can make (and not break) for a healthier 2025.
The conversation shifts away from unattainable goals and toward practical steps for enhancing overall well-being in the new year.
Key Takeaways:
Address Metabolic SyndromeIf you suspect you have metabolic syndrome, 2025 is the year
Mailbag: Questions From You!
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright field questions from listeners. Throughout the show, our hosts highlight the importance of compassionate, science-based medical care and underscore the significance of finding healthcare providers who address metabolic issues as medical, not lifestyle, concerns.
Among the topics addressed:
Statins & Weight Gain
Metabolic Meds: What’s Now & What’s Next!
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright take a comprehensive look at the current FDA-approved medications designed to treat metabolic dysfunction and what may be approved next.
Dr. Cooper discusses the range of factors that determine whether these essential drugs are available for those who need them. Government approval, drug company strategies and insuran
Metabolic Markers: The Power of Your Blood Lab Results
In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright reveal how metabolic lab tests are crucial in diagnosing, understanding and treating metabolic dysfunction.
Key Takeaways:
Metabolic Functions:
Understanding blood markers like glucose, insulin, and cholesterol offers in-depth knowledge about overall health.
Metabolic Syndrome:
Defined by issues like pre-diabetes,
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