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Trying To Be Positive With Anne Matthews

Trying To Be Positive With Anne Matthews

Anne Matthews, RTF Productions 50 Episodes May 26, 2026

Trying to Be Positive is a podcast hosted by Anne Matthews, a passionate advocate for reproductive health. The show aims to normalize conversations around fertility, labour, loss, and menstruation. Anne offers tools and support for those on their fertility journey, drawing from her experience as a busy clinician. Listeners can expect practical advice and emotional encouragement.

Episodes

PCOS Is Now PMOS: What the Rename Means for Your Fertility, IVF & Metabolic Health
PCOS Is Now PMOS: What the Rename Means for Your Fertility, IVF & Metabolic Health May 26, 2026 00:43:16 Anne is back with a solo episode on one of the biggest shifts happening in women's health right now: the rename from PCOS (polycystic ovarian syndrome) to PMOS (polyendocrine metabolic ovarian syndrome). She breaks down why the old name was misleading, why many women with PCOS never actually had ovarian cysts and why many women with polycystic-looking ovaries were completely hormonally well, a
Male Factor Infertility: Varicocele, DNA Fragmentation & Recurrent Loss - A Fertility Story
Male Factor Infertility: Varicocele, DNA Fragmentation & Recurrent Loss - A Fertility Story May 5, 2026 00:53:38 Anne is back with Nico, her first male guest sharing a male factor story. Nico walks through DNA fragmentation climbing from 15% to 24% despite lifestyle changes, discovering he'd had an undiagnosed varicocele for 20 years, being dismissed by urologists who said his wife's PCOS was the real problem, and advocating for surgery that dropped fragmentation to 14%. After immune testing revealed
A Fertility Story - PCOS, Failed IUIs & Endometriosis: LAD Testing at 7%, LIT Therapy & Getting Pregnant Naturally
A Fertility Story - PCOS, Failed IUIs & Endometriosis: LAD Testing at 7%, LIT Therapy & Getting Pregnant Naturally Apr 14, 2026 00:32:01 Anne is back with Sarah, who spent three and a half years navigating PCOS, two miscarriages, failed IUIs, and a fertility system that kept offering IVF without explaining why. Sarah shares how she got pregnant spontaneously right after her wedding, lost it at eight weeks, then spent over a year on medicated cycles that went nowhere. She walks through how Anne clocked her GI issues as endometriosis
A Fertility Story - Recurrent Miscarriage & Immune Testing: Five Losses, Varicocele Repair & Refusing Unexplained
A Fertility Story - Recurrent Miscarriage & Immune Testing: Five Losses, Varicocele Repair & Refusing Unexplained Mar 31, 2026 00:56:29 Anne is back with Anna, one of her first patients dealing with immune-related infertility. Anna shares her four-year journey through five miscarriages, multiple failed IVF transfers, and the medical dismissals that made her stop trusting anyone in the system. She walks through what happened when her husband's varicocele and high DNA fragmentation were finally addressed mid-IVF cycle, why her clini
Explaining Unexplained Infertility: DNA Fragmentation, Immune Testing & Why Your Lining Matters
Explaining Unexplained Infertility: DNA Fragmentation, Immune Testing & Why Your Lining Matters Mar 17, 2026 00:56:27 Anne is back tackling the most frustrating diagnosis in fertility medicine: unexplained infertility. She breaks down why this label almost always means the right questions haven't been asked yet, not that there's actually nothing wrong. She explains how varicoceles affect DNA fragmentation even when sperm count looks perfect, why DOR is overdiagnosed and often not the real problem, how fai
Fertility Clinic Red Flags: Spilling the Tea on Cookie-Cutter Care & What to Ask For
Fertility Clinic Red Flags: Spilling the Tea on Cookie-Cutter Care & What to Ask For Mar 3, 2026 00:43:02 Today, Anne tackles the influx of questions from patients feeling let down, gaslit, and stuck in the fertility clinic system. We are diving deep into the diagnostics your clinic should be running—and exactly what to do if they refuse. From the necessity of immune testing to the critical role of blood thinners in preventing recurrent loss, this is your ultimate guide to self-advocacy.00:00 Intro01:
Fertility Questions I Answer Every Day in Clinic: DNA Fragmentation, Exercise, Coffee & Age
Fertility Questions I Answer Every Day in Clinic: DNA Fragmentation, Exercise, Coffee & Age Feb 10, 2026 00:41:22 Anne is back answering the fertility questions she hears most often from patients—not the ones from Instagram AMAs, but the real concerns that come up after people have already made lifestyle changes. She covers why DNA fragmentation testing matters despite what some clinics say, how much exercise actually helps (or hurts) fertility, whether coffee is sabotaging your chances, why your friend's
Unexplained Infertility, High NK Cells & Saying No to IVF: Fran’s Story
Unexplained Infertility, High NK Cells & Saying No to IVF: Fran’s Story Dec 9, 2025 00:53:40 When Anne first met Fran, she thought to herself, "She’s a youth... this is going to be a slam dunk."Fran was 26, incredibly healthy, and fit. But after a year of negative tests and chemical pregnancies, she was slapped with the frustrating diagnosis of "Unexplained Infertility" and told that IVF was her only real option.In this episode, we share Fran’s Story, a powerful journe
AMA: Iron Deficiency & Unexplained Infertility, Luteal Phase Defects vs. Low Progesterone, How Stress Affects Your Cycle & Essential Advice for Patients Over 35
AMA: Iron Deficiency & Unexplained Infertility, Luteal Phase Defects vs. Low Progesterone, How Stress Affects Your Cycle & Essential Advice for Patients Over 35 Nov 25, 2025 00:28:52 In this Ask Me Anything episode, Anne tackles listener questions about some of the most misunderstood aspects of fertility. From why your doctor might not be testing your ferritin levels (even though they should) to the real story behind luteal phase defects and what stress actually does to your fertility journey.We dive into practical topics like optimal iron ranges for conception, why adding pro
Your Most-Asked Fertility Questions, Answered with Honesty, Science, and a Little Humor
Your Most-Asked Fertility Questions, Answered with Honesty, Science, and a Little Humor Oct 21, 2025 00:43:02 Anne is back with an open and honest fertility Q&A, tackling the questions she gets most often from patients and listeners. From embryo grading and PGT-A testing to sperm DNA fragmentation, egg versus embryo freezing, and how often to have sex when trying to conceive, Anne breaks down the science!
Laura’s Journey Through MS, Endometriosis, and IVF
Laura’s Journey Through MS, Endometriosis, and IVF Oct 7, 2025 01:02:49 Laura’s story is one of quiet strength and persistence. She opens up about navigating MS, endometriosis, and the realities of using donor sperm while trying to grow her family. After failed IUIs, unexpected surgery, and just one remaining embryo, she learned to trust her body and advocate for herself in a system that didn’t always listen.What followed was a mix of setbacks, small shifts, and self-
Answering Your Fertility Questions: IVF Costs, Implantation Failure, Male Factor, and Staying Hopeful
Answering Your Fertility Questions: IVF Costs, Implantation Failure, Male Factor, and Staying Hopeful Sep 23, 2025 00:44:28 In this episode of Trying to Be Positive, Anne answers your questions: what Ontario’s new IVF funding actually covers, why sperm DNA fragmentation can tank “normal” semen analyses, how frequent release + antioxidants may help, why high cholesterol affects sperm, what to know about supplements (CoQ10, omega-3, folate) without overdoing it - plus practical ways to stay hopeful when you feel like you

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