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The Proof with Simon Hill

The Proof with Simon Hill

Live better for longer 416 Episodes Sep 14, 2026

The Proof Podcast is a science-based conversation hosted by Simon Hill, a qualified physiotherapist and nutritionist. It explores health and longevity benefits through exercise, nutrition, mindfulness, recovery, sleep, and alignment. The show provides facts, nuance, and trustworthy recommendations without hyperbole.

Episodes

The Liver Disease 30% of Us Have and Never Feel | Prof Aleksander Krag
The Liver Disease 30% of Us Have and Never Feel | Prof Aleksander Krag Sep 14, 2026 4855 Around 30% of the world's population has too much fat in their liver, and almost none of them know it. Liver disease stays silent until it is very advanced, which is exactly why so many people are found too late. In this episode I sit down with Prof Aleksander Krag, professor and department chair of gastroenterology and hepatology at Odense University Hospital and former Secretary General of the
The Case for Treating Cholesterol Before Plaque Appears | Dr Thomas Dayspring and Dr Dan Soffer
The Case for Treating Cholesterol Before Plaque Appears | Dr Thomas Dayspring and Dr Dan Soffer Sep 7, 2026 6130 Almost all of us have atherosclerosis, and almost none of us are told so, because "normal" cholesterol is a population average rather than a physiological target. Dr Thomas Dayspring and Dr Dan Soffer, both Masters of the National Lipid Association, join me for a conversation devoted entirely to primary prevention. They do not agree on everything, and that is the point. Tom argues ApoB is the cau
Bone Health, Falls, Medications & Healthy Longevity | Dr Deborah Kado
Bone Health, Falls, Medications & Healthy Longevity | Dr Deborah Kado Aug 31, 2026 5717 Everyone wants to talk about longevity. Almost no one wants to talk about gerontology, the field that has been studying how to age well for a century. Dr Deborah Kado, Stanford professor of medicine and geriatrician, joins me to bridge that gap. From bone health and balance to deprescribing, gut microbiome research, and the surprising power of your attitude towards ageing, this is a masterclass i
Type 2 Diabetes Remission in the GLP-1 Era | Prof Roy Taylor
Type 2 Diabetes Remission in the GLP-1 Era | Prof Roy Taylor Aug 25, 2026 5086 Professor Roy Taylor returns, three years after his first appearance, with the five-year DiRECT trial results and a clear-eyed assessment of where diet-driven type 2 diabetes remission stands in the GLP-1 era. The evidence is now solid: type 2 diabetes is, for many, a reversible condition of excess fat in the liver and pancreas. But keeping it in remission demands keeping the weight off, and the
Lowering Blood Sugar Without Weight Loss | Dr Nicola Guess
Lowering Blood Sugar Without Weight Loss | Dr Nicola Guess Aug 17, 2026 4136 Can you meaningfully improve type 2 diabetes without losing weight? Dr Nicola Guess, registered dietitian and Senior Research Fellow at the University of Oxford, says the evidence is clear: a higher-protein, lower-carbohydrate diet can lower post-meal glucose by more than medication, no weight loss required. We also tackle the noisier end of the blood sugar conversation: glucose spikes, fruit fea
The Fertility Test Most Men Are Never Offered | Dr Michael Eisenberg and Dr Natalie Crawford
The Fertility Test Most Men Are Never Offered | Dr Michael Eisenberg and Dr Natalie Crawford Aug 10, 2026 7423 About one in seven couples are unable to conceive after a year of trying, and roughly half of those cases involve a male contribution. Yet in a quarter to a third of them, the man is never properly evaluated. In this episode I sit down with Dr Michael Eisenberg, a urologist, Director of Male Reproductive Health at Stanford University and Chief Medical Advisor of SwimClub, and Dr Natalie Crawford,
Superagers, statins, the latest cholesterol pill and the truth about heart disease risk | Dr Terry Simpson
Superagers, statins, the latest cholesterol pill and the truth about heart disease risk | Dr Terry Simpson Aug 4, 2026 6803 Dr Terry Simpson is back, and we go deep on the science of protecting your heart and brain for the long run. He is a surgeon and one of the clearest voices online for separating solid evidence from confident hype, and in this conversation we tackle everything from new cholesterol-lowering drugs to gene editing, cognitive ageing, and the lean mass hyperresponder debate. Along the way we get a few
The Science of Metabolic Flexibility, Zone 2, and Reversing Diabetes | A Masterclass
The Science of Metabolic Flexibility, Zone 2, and Reversing Diabetes | A Masterclass Jul 27, 2026 8428 Metabolic dysfunction rarely announces itself. We tend to think of metabolic health as a line you cross the day you are diagnosed with type 2 diabetes, but the decay usually begins years earlier, at the level of the cell. In this masterclass I bring together Dr Iñigo San Millán, Dr Alan Flanagan, Dr Kevin Hall, Dr Robert Eckel, Professor Roy Taylor, and Dr Christos Mantzoros to explain what metabo
New Science of Weight Loss | A Masterclass
New Science of Weight Loss | A Masterclass Jul 20, 2026 6886 GLP-1 medications are transforming obesity treatment, but they're only one piece of the puzzle. In this masterclass, I bring together insights from Dr Terry Simpson, Dr Federica Amati, Dr Mauricio Gonzalez, Dr Christos Mantzoros, and Dr Stephan Guyenet to explain how these medications work, why "food noise" matters, and what it really takes to improve long-term metabolic health. What We Cover
Fertility, Sperm Health, and Nutrition Before and During Pregnancy | Dr Federica Amati
Fertility, Sperm Health, and Nutrition Before and During Pregnancy | Dr Federica Amati Jul 13, 2026 5016 We tend to treat pregnancy as the starting line for a child's health. In this episode, Dr Federica Amati, Head Nutritionist at ZOE, makes the evidence-based case that the window opens earlier, in the months before conception, and that it shapes fertility and lifelong health in ways most of us were never told. What I valued most is her balance. The science is striking, but she frames it as informa
Can You Reverse Heart Disease? What My Plaque Scans Showed | Dr Campbell Rogers
Can You Reverse Heart Disease? What My Plaque Scans Showed | Dr Campbell Rogers Jul 6, 2026 4515 In late 2024 a CT scan revealed a small amount of soft plaque in my arteries. Sixteen months later I scanned again, and my plaque volume had dropped by around forty percent. In this episode I ask the cardiologist behind the technology whether a result like that can really be trusted. Dr Campbell Rogers is an interventional cardiologist, a former Harvard faculty member who ran the cath lab at Brig
Reversing Artery Plaque: 8 Supplements Ranked by the Evidence | Simon Hill, MSc
Reversing Artery Plaque: 8 Supplements Ranked by the Evidence | Simon Hill, MSc Jun 29, 2026 3697 Can a supplement actually reverse the plaque in your arteries, or only slow it down? It is the question I am asked most, and after a 2024 scan revealed early plaque in my own left anterior descending artery, it became a personal one too. This is part two of my three-part series on reversing atherosclerosis. In this solo episode I work through eight of the most popular supplements and rank them by

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