National HIV Curriculum Podcast
This podcast series explores practice-changing issues and updates in HIV diagnosis, management, and prevention. It features Case Discussions, Expert Interviews, Literature Reviews, and Conference Summaries hosted by Dr. Brian Wood, Dr. Jehan Budak, and Dr. Aley Kalapila. The content is produced by the University of Washington Infectious Diseases Education & Assessment (IDEA) Program.
Episodes
Evaluation and Management of Isolated Hepatitis B Core Antibody for Persons with HIV
In this National HIV Curriculum podcast episode, Dr. Brian Wood, Editor for the podcast series, interviews Dr. Kim, an expert in viral hepatitis, to discuss the evaluation and management of isolated hepatitis B core positivity for people with HIV. View episode transcript and references at www.hiv.uw.edu. This podcast explores practice-changing issues and updates in HIV diagnosis, management, and p
Diagnosis, Evaluation, and Management of Chronic Diarrhea in People with HIV
National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila present a clinical case study to discuss the evaluation and management of chronic diarrhea in people with HIV, including cryptosporidiosis, cystoisosporiasis, and microsporidiosis. View episode transcript at www.hiv.uw.edu. This podcast explores practice-changing issues and updates in HIV diagnosis, management, and preve
Priority Immunizations for People with HIV (Part 2)
Dr. Shireesha Dhanireddy, an expert in HIV prevention and treatment, once again joins National HIV Curriculum Podcast Lead Editor Dr. Brian Wood to discuss vaccinations for adults with HIV. This episode focuses on optimal management of hepatitis A and hepatitis B vaccinations, as well as best practice strategies for measles immunization for adults with HIV. View episode transcript at www.hiv.uw.ed
Priority Immunizations for People with HIV
Dr. Shireesha Dhanireddy, an expert in HIV prevention and treatment, joins National HIV Curriculum Podcast Lead Editor Dr. Brian Wood to discuss challenging clinical questions about vaccinations for adults with HIV. This case-based discussion will focus on how to select and prioritize immunizations for individuals with advanced HIV. View episode transcript at www.hiv.uw.edu. This podcast explores
Occupational PEP Guidelines: 2025 Update
National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila discuss an occupational needlestick exposure as they highlight key updates to recommended medications regimens and laboratory monitoring included in the “2025 US Public Health Service Guidelines for the Management of Occupational Exposures to Human Immunodeficiency Virus and Recommendations for Post-exposure Prophylaxis
The BEe-HIVe Study: Major Findings from Two Publications
This episode reviews two recent papers on the practice-changing BEe-HIVe study, which assessed efficacy of a relatively new hepatitis B vaccine (known as HepB-CpG, or trade name Heplisav-B) for persons with HIV, and the resulting clinical implications. View episode transcript and references at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, a
Hepatitis C and HIV Coinfection: Diagnosis and Management
National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila discuss the diagnosis and management of hepatitis C co-infection in persons with HIV, including direct acting antiviral (DAA) therapy, use of the simplified treatment algorithm, and post-treatment follow-up. View episode transcript and links at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in
PML: Evaluation and Management
National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila discuss their approach to diagnosing and managing Progressive Multifocal Leukoencephalopathy (PML) in a person with advanced HIV. View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, and prevention. The three podcast hosts include Lead Editor D
Integrating Injectable ART into Clinical Practice
Long-acting injectable ART (LAI) was not initially considered to be a treatment option for individuals with substantial barriers to taking oral ART. However, our understanding has evolved due to the experience of several clinics around the country, including the team at University of Mississippi Medical Center. In this episode, Dr. James “Ben” Brock, Associate Professor of Medicine, discusses prac
Initial Laboratory Evaluation of a Person with HIV
National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila discuss their approach to the initial laboratory evaluation with a person newly diagnosed with HIV, including HIV-specific, co-infection screening, and healthcare maintenance labs. View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, and preven
CROI 2025: Four More Potentially Practice-Changing Abstracts
Dr. Jehan Budak and Dr. Raaka Kumbhakar, University of Washington Assistant Professors of Medicine, discuss CROI 2025 abstracts on the complexities of treating TB during pregnancy, the use of tenofovir alafenamide for people with TB, switching to the investigational ART combination doravirine/islatravir, and data on why people stop injectable cabotegravir/rilpivirine. View episode transcript and r
CROI 2025: CARES and BEeHIVe Studies and Their Potential Practice-Changing Impacts
What were the CROI 2025 major scientific research themes and the key findings from the CARES trial on long-acting injectable ART and the BEeHIVe study on hepatitis B vaccines for people with HIV? Drs. Jehan Budak and Raaka Kumbhakar, co-assistant directors of a Ryan White-funded HIV Clinic, discuss major themes, the two studies, and how their clinical practice has already changed. View episode tra
Initial Visit & Evaluation for a Person with HIV
National HIV Curriculum Podcast editors Dr. Jehan Budak and Dr. Aley Kalapila discuss their approaches and key questions they ask during an initial visit and evaluation with a person who’s new to their clinic. View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, and prevention. The three podcast hosts include Lead Editor
LATITUDE Study: Interim Findings and Implications
Dr. Aadia Rana, University of Alabama Birmingham Professor of Medicine and LATITUDE Study Chair, discusses the LATITUDE Study’s key findings to date and considerations for prescribing long-acting ART for individuals who struggle to take oral medications or who have detectable viral loads. View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV di
Implementation of the New HHS Anal Cancer Screening Guidelines
Dr. Jeff Schouten, UW faculty in Surgery and in Allergy and Infectious Diseases as well as ANCHOR trial co-investigator, discusses the new anal cancer screening guidelines for persons with HIV then focuses on implementation barriers and considerations for integrating the new recommendations into HIV primary care clinical practice. View episode transcript and access links at www.hiv.uw.edu.This pod
The ANCHOR Study: Does Treatment of Anal HSIL Prevent Anal Cancer?
This episode reviews a landmark study published in 2022 that aimed to answer the question of whether treating anal high-grade squamous intraepithelial lesions (HSIL) prevents anal cancer for persons with HIV, a question that was previously unanswered and that was key to informing the new anal cancer screening guidelines. View episode transcript and link to the article at www.hiv.uw.edu.This podcas
The SLIM LIVER Study: Use of Semaglutide for Persons with HIV
This episode reviews literature about the recent SLIM LIVER study which evaluated the impact of semaglutide, a GLP-1 receptor agonist, on persons with HIV and discusses the important implications on clinical practice. View episode transcript, links to the literature, and the tables at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, and preven
Neurosyphilis: Evaluation and Management
National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila discuss their approach to diagnosing and treating neurosyphilis in a person with HIV, including clinical manifestations, diagnostics, treatment, and therapeutic monitoring. View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, and prevention. Th
Switching ART Regimens: A Discussion
The three National HIV Curriculum Podcast editors discuss the multiple factors they consider before switching to another oral ART option or to injectable cabotegravir/rilpivirine, including adherence, patient preference, weight gain, NRTI resistance, HBV status, and dosing schedules. View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnos
Disseminated MAC: Evaluation and Management
National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila discuss their approach to diagnosing and treating disseminated Mycobacterium avium complex in a person with advanced HIV, including prophylaxis and management of the infection and immune reconstitution inflammatory syndrome (IRIS). View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues a
Initial ART Regimens Considerations: A Discussion
The three National HIV Curriculum Podcast editors share their perspectives on recent guideline changes to initial ART choices for treatment-naïve individuals with HIV, practical considerations for first line and alternate ART regimens, and the impact of M184V mutation. View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management,
Pneumocystis Pneumonia: Management
National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila discuss their approach to treating Pneumocystis Pneumonia (PCP or PJP) in a person with advanced HIV, including the use of antimicrobials, adjunctive steroids, and when to start ART. View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, and prev
Evaluation of Dyspnea in a Person with Advanced HIV
Dyspnea in persons with advanced HIV has a broad differential diagnosis. National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila discuss potential causes and diagnostic options with a specific focus on the wide array of diagnostics for Pneumocystis pneumonia (PCP), including blood tests, sputum stain types, DFA, and PCP PCR. View episode transcript at www.hiv.uw.edu.This podc
Semaglutide Studies in PWH & What to Consider Before Prescribing
Dr. Kristine Erlandson, Associate Professor at the University of Colorado School of Medicine and SLIM LIVER study senior author, discusses recent key GLP-1 receptor agonist studies, clinical implications, and practical prescribing considerations for HIV primary care providers with National HIV Curriculum Podcast Lead Editor Dr. Brian Wood. View episode transcript and references at www.hiv.uw.edu.T
CMV Retinitis: Evaluation and Management
National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila discuss possible causes of visual changes in advanced HIV and the diagnosis and management of CMV retinitis in people with HIV. View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, and prevention. The three podcast hosts include Lead Editor Dr.
Should People with HIV Take Aspirin for CVD Prevention?
HIV exacerbates the risk for adverse cardiovascular events. Dr. Chris Longenecker, a University of Washington Associate Professor of Medicine, and National HIV Curriculum Podcast Lead Editor Dr. Brian Wood discuss the pros and cons around aspirin for primary prevention and how to counsel patients. View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues and updates
Toxoplasma Encephalitis: Management
National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila discuss the diagnosis and treatment of toxoplasma encephalitis, potential side effects, and when to start or restart HIV antiretroviral therapy. View episode transcript and references at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, and prevention. The three podca
Cardiovascular Side Effects of Antiretroviral Therapy
Dr. Chris Longenecker, a University of Washington Associate Professor of Medicine, discusses the cardiovascular side effects, including effects on lipids, of common antiretroviral therapy (ART) drugs with National HIV Curriculum Podcast Lead Editor Dr. Brian Wood. View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, and
Evaluation of Focal Neurological Symptoms in a Patient with Advanced HIV
National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila discuss an approach to working up a patient with a CD4 <100 who presented with focal neurological deficits and abnormal brain imaging. View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, and prevention. The three podcast hosts include Lead
New Guidelines: Statin Therapy for People with HIV to Prevent CVD
The first ever statin therapy guidelines to prevent cardiovascular disease (CVD) in people with HIV were released February 27, 2024. Dr. Chris Longenecker, a University of Washington Associate Professor of Medicine, and National HIV Curriculum Podcast Lead Editor Dr. Brian Wood discuss the recommendations and their clinical implications. View episode transcript at www.hiv.uw.edu.This podcast explo
Pharmacologic Management of Hyperlipidemia
Dr. Chris Longenecker, a University of Washington Associate Professor of Medicine, and National HIV Curriculum Podcast Lead Editor Dr. Brian Wood discuss treatment of hyperlipidemia for individuals with HIV (PWH), with a focus on tools to estimate cardiovascular disease risk, selecting lipid-lowering agents, and key drug-drug interactions, as well as managing adverse effects or nonresponse to init
Management of Cryptococcal Meningitis
After diagnosing cryptococcal meningitis in the last episode, National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila review the complexities of managing a patient with HIV and cryptococcal meningitis. View episode transcript at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, and prevention. The three podcast hosts incl
REPRIEVE Statin Trial: Why is It Important?
Dr. Chris Longenecker, a University of Washington Associate Professor of Medicine, discusses the REPRIEVE trial design and clinical practice implications with National HIV Curriculum Podcast Lead Editor Dr. Brian Wood. View episode transcript and references at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, and prevention. The three podcast h
Evaluation of a Headache in Advanced HIV
National HIV Curriculum Podcast Editors Dr. Jehan Budak and Dr. Aley Kalapila discuss an approach to working up a headache in a patient with a CD4 count less than a 100. View episode transcript and references at www.hiv.uw.edu.This podcast explores practice-changing issues and updates in HIV diagnosis, management, and prevention. The three podcast hosts include Lead Editor Dr. Brian Wood, Associat
Antiretroviral Therapy (ART) and Weight Gain
Managing weight gain with the use of newer generation HIV ART regimens is controversial. Dr. Sara Bares, a University of Nebraska Associate Professor, discusses key studies and how to counsel patients about potential impacts of initiating or switching a regimen with National HIV Curriculum Podcast Lead Editor Dr. Brian Wood. View episode transcript at www.hiv.uw.edu.This podcast explores practice-
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