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Sleep Unplugged with Dr. Chris Winter

Sleep Unplugged with Dr. Chris Winter

Chris Winter, MD 216 Episodes Oct 12, 2026

Dr. Chris Winter, a board-certified neurologist and sleep specialist, hosts this unscripted podcast exploring sleep-related topics. He covers sleep disorders, current research, and controversies in the field. With 30 years of clinical experience, he shares insights from his books 'The Sleep Solution' and 'The Rested Child'. The show aims to demystify sleep for a general audience.

Episodes

#225 - Orexin Agonist Update: The Big Reward is Here (Lifting Humanity Higher)
#225 - Orexin Agonist Update: The Big Reward is Here (Lifting Humanity Higher) Oct 12, 2026 2802 Last November on Episode 178, we talked about three companies racing to bring orexin agonists to people with narcolepsy. In less than a year, one of those drugs has been approved, another company has been bought for billions, and the race now runs from the lab to the insurance company. In this episode we will:Break down the latest data from the SLEEP 2026 meeting in Baltimore, where each drug stan
#224 - Why Do All Insomnia Therapies “Work”?: Tryin So Hard To Make the Grade
#224 - Why Do All Insomnia Therapies “Work”?: Tryin So Hard To Make the Grade Oct 5, 2026 2573 Imagine a sleep study where picturing yourself diving in a submarine boosted deep sleep by 81%, yet nobody slept a minute longer. It's a real result, and it points to an uncomfortable idea: with the right design, almost anything can be shown to "improve sleep." From free habits to FDA-approved pills to neurotech headbands, every claim has a study behind it, and how that study was bu
#223 - Top 10 Sleep Threat Power Rankings: Ain’t Nobody Worried
#223 - Top 10 Sleep Threat Power Rankings: Ain’t Nobody Worried Sep 28, 2026 3003 Dr. Valerie Cacho (@drvalsleepgal) joins me for another countdown of the Top 10 Sleep Threats, and her list asks a question we should all be asking more often: Have we actually figured out what is disrupting someone’s sleep? From peptides marketed as cures to the assumption that a woman’s fatigue is simply part of being a working mom, Valerie takes aim at the shortcuts that can delay an accurate d
#222 - How Much Is A Night of Sleep Worth: Break It On Down
#222 - How Much Is A Night of Sleep Worth: Break It On Down Sep 21, 2026 2189 A courtroom, an insurance formula, and a supermarket receipt don't usually belong in the same sentence — but together they answer the question this episode is built around: what does a bad night's sleep actually cost, in dollars, tonight? Not the economy. You. We take the number everyone quotes and can't act on — sleep deprivation costs the U.S. $411 billion a year — and rebuild it
Bonus - The AI Interview Experiment...UNHINGED: Wish I Knew What You Were Looking For
Bonus - The AI Interview Experiment...UNHINGED: Wish I Knew What You Were Looking For Sep 16, 2026 1927 A few days ago, we did an experiment to see how well AI could interview me about sleep. In this bonus episode, I reveal the original attempt which was a bit all over the place. The interview was much more personal and strange which we corrected by adjusting the prompt in the "official" episode, but I thought it might be funny to share the trial run. In this episode we will:-Debate how mu
#221 - The AI Interview Experiment: Wish I Knew What You Were Looking For
#221 - The AI Interview Experiment: Wish I Knew What You Were Looking For Sep 14, 2026 1736 What happens when the interviewer knows nearly everything you have said publicly and has zero fear of challenging or offending you? In this unusual episode of Sleep Unplugged, I turn over all control of the podcast to AI and let it ask the questions and dictate the program. The result is a surprisingly candid conversation about certainty, contradiction, expertise, and what an algorithm might see w
#220 - The Lindsay Clancy Tragedy: Insomnia, Overmedication, and the Psychiatric Safety Net
#220 - The Lindsay Clancy Tragedy: Insomnia, Overmedication, and the Psychiatric Safety Net Sep 7, 2026 2920 A Massachusetts courtroom just produced something that almost never survives into public record: a near-complete paper trail of one woman's psychiatric care in the three months before catastrophe. Her diary, her phone notes, and the testimony of every provider who tried to help her sleep all lead to a central question: what actually happens when insomnia and psychiatric illness feed each othe
#219 - Top 10 Sleep Threat Power Rankings: Trapped Inside Disillusion
#219 - Top 10 Sleep Threat Power Rankings: Trapped Inside Disillusion Aug 31, 2026 2582 Dr. Alison Kole is taking on sleepmaxxing, ChatGPT, and the sleep-industrial complex in her Top 10 Sleep Threat list. In this episode we will:Explore why patients sometimes arrive at the sleep clinic with their story and diagnosis already writtenLook at the fear of sleep studies, sleep apnea diagnoses, and outdated ideas about CPAPAsk why CBT-I remains underused despite being the gold-standard fir
#218 - Medication Deprescribing: Get Off This
#218 - Medication Deprescribing: Get Off This Aug 24, 2026 2627 Nobody blinks when a doctor says you'll be on blood pressure medication for the rest of your life. Say the same sentence about an antidepressant, or Zepbound, and responses are quite different. This episode digs into deprescribing, the fast-growing clinical movement around when and how to stop medications, and asks why some "forever drugs" get a cultural pass while others get morali
#217 - Modern Night Shift and Circadian Adaptation: Up All Night
#217 - Modern Night Shift and Circadian Adaptation: Up All Night Aug 17, 2026 1894 Our current gig economy did not just create new jobs, it expanded a whole new category of night worker, from rideshare drivers to online freelancers to overnight fulfillment teams. Today (or tonight rather), our bodies are struggling to make the switch. In this episode we dig into what that circadian resistance actually costs your heart and metabolism long-term, and the handful of interventions th
#216 - Nasal Strips and Sleep: Leave Me Breathless
#216 - Nasal Strips and Sleep: Leave Me Breathless Aug 10, 2026 1481 Nasal strips have been a fixture in pharmacy aisles and on athletes' faces for decades, sold on the promise of easier breathing, but the peer-reviewed evidence often tells a different story than the packaging does. We put nasal strips and internal dilators through the RCT wringer and sort out what these devices can and can't actually do, from your bedroom to the finish line. In this epis
#215 - Seqoquel and Insomnia: Same Thing From The Same Old Cause
#215 - Seqoquel and Insomnia: Same Thing From The Same Old Cause Aug 3, 2026 2476 Ten million prescriptions a year, and most of them aren't for what the drug was built to treat. Seroquel started life as an antipsychotic — engineered to quiet psychosis, not close your eyes. Somewhere along the way it became one of the most common "off the record" sleep aids in America, riding on a side effect nobody set out to sell. The evidence behind that shift is thinner than m

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