The Egg Factor
Hosted by Dr. Norbert Gleicher, a fertility specialist with over 40 years of experience, The Egg Factor explores the latest research and developments in fertility care. Each episode covers advances in reproductive technology and practical ways to optimize fertility naturally. The podcast emphasizes evidence-based research and personalized treatment approaches. It is designed for anyone starting their fertility journey or seeking advanced solutions to improve their chances of conception.
Episodes
Does Fresh Transfer vs Frozen Transfer Matter in Women Over 40?
In this episode of The Egg Factor, Dr. Norbert Gleicher explores whether fresh or frozen embryo transfers may lead to different outcomes for women over 40. He discusses the science behind each approach and why individualized treatment decisions are especially important as reproductive age increases.Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. W
Does Every Woman With Endometriosis Need IVF?
Endometriosis is one of the most common causes of infertility, but does a diagnosis automatically mean IVF is the next step? In this episode of The Egg Factor, Dr. Sonia Gayete-Lafuente explores the relationship between endometriosis and fertility, explaining why every patient's journey is different.Tune in as she discusses how endometriosis can affect reproductive health, when IVF may be rec
The Future of Fertility: AI, Genetics, and Beyond
In this episode of The Egg Factor, Dr. Norbert Gleicher is joined by Dr. Pasquale Patrizio and Dr. David Albertini for a thought-provoking conversation about the rapidly evolving field of reproductive medicine.Together, they explore the growing role of artificial intelligence, genetics, advanced reproductive technologies, and emerging scientific approaches and how these developments could influenc
Stem Cells and Future Fertility Treatments
In this episode of The Egg Factor, Dr. Norbert Gleicher explores the potential of stem cells and what they could mean for the future of fertility treatment. He discusses emerging research, possibilities for reproductive medicine, and where this evolving field may be headed.Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of exper
AI in Embryo Selection
In this episode of The Egg Factor, Dr. Norbert Gleicher explores the growing role of artificial intelligence in embryo selection. He discusses how AI is being used to evaluate embryos, what the technology can and cannot tell us, and what its future could mean for IVF and other fertility treatments.Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. Wi
PMOS Awareness Month
In recognition of PMOS Awareness Month, Dr. Sonia Gayete-Lafuente discusses polyendocrine metabolic syndrome (PMOS) and its connection to reproductive health. She explores how PMOS can affect fertility, why understanding the condition is important, and what patients should know when seeking care.Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With
What "Unexplained Infertility" means at CHR vs. Elsewhere
What does it really mean when infertility is labeled “unexplained”? In this episode of The Egg Factor, Dr. Norbert Gleicher discusses why that diagnosis may look different at the Center for Human Reproduction compared with other fertility centers, and why identifying underlying causes can be an important part of developing a more personalized treatment approach.Brought to you by the Center for Hum
Why Is The Immune System So Overlooked In Reproductive Medicine?
In this episode of The Egg Factor, Dr. Norbert Gleicher explores the growing body of research on reproductive immunology and discusses why immune function deserves greater attention in fertility care.Join Dr. Gleicher as he explains how the immune system can influence reproductive outcomes, why this area of medicine remains controversial, and what emerging evidence may mean for patients experienci
Should Younger Women Freeze Eggs or Not?
On this episode of The Egg Factor, Dr. Norbert Gleicher explores whether younger women should consider freezing their eggs. He discusses how age, egg quality, ovarian reserve, and future fertility goals can factor into the decision and why egg freezing isn’t necessarily the right choice for everyone.Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City.
Can Genetics Explain Repeated Pregnancy Loss?
Can genetics help explain repeated pregnancy loss? While many pregnancy losses are caused by chromosomal abnormalities, not all cases have a clear explanation. In this episode of The Egg Factor, Dr. Norbert Gleicher explores the complex relationship between genetics and recurrent pregnancy loss.Whether you've experienced recurrent pregnancy loss or want to learn more about the latest advances
Non-Invasive Embryo Testing
In this episode of The Egg Factor, Dr. Norbert Gleicher explores the science behind non-invasive embryo testing and what it could mean for the future of IVF. Learn how these methods compare to traditional genetic testing, and where the research stands today.Join us as we discuss the potential benefits, current limitations, and what patients should know when considering the latest advances in embry
Understanding DOR, POA, and POI
What do Diminished Ovarian Reserve (DOR), Premature Ovarian Aging (POA), and Primary Ovarian Insufficiency (POI) really mean—and how are they different?In this episode of The Egg Factor, Dr. Sonia Gayete-Lafuente breaks down these often-confused diagnoses, explaining how they're identified, what they mean for fertility, and the treatment options available. Whether you're navigating your
Recurrent Implantation Failure
In this episode of The Egg Factor, Dr. Norbert Gleicher takes a closer look at recurrent implantation failure — a complex and often frustrating challenge for patients undergoing fertility treatment. He discusses what defines recurrent implantation failure, the many factors that may contribute to unsuccessful implantation, and how a thorough evaluation can help identify potential underlying causes.
Natural Cycle IVF vs Stimulated Cycles
In this episode of The Egg Factor, Dr. Norbert Gleicher and Dr. David Barad sit down to discuss the topic of Natural Cycle IVF vs Stimulated Cycles. Learn how each approach works, who may benefit from each option, and the key factors to consider when choosing a treatment path. Whether you're beginning your fertility journey or looking to better understand your options, this episode offers cle
What We’ve Learned From Transferring “Abnormal” Embryos
In this episode, Dr. Norbert Gleicher discusses what has been learned from transferring embryos identified as chromosomally abnormal during IVF treatment. He explores how these cases have challenged assumptions about embryo selection, implantation potential, and the role of genetic testing in fertility care, providing important insights for patients and clinicians navigating IVF decisions.Brought
Low Testosterone in Women
In this video, Dr. Norbert Gleicher discusses how low testosterone can affect ovarian function, egg development, and reproductive health in women. He explains why balanced hormone levels are important for fertility and how testosterone may be considered as part of an individualized approach to fertility care in selected patients. Brought to you by the Center for Human Reproduction (CHR) on the Upp
Can We Slow Ovarian Aging?
In this episode of The Egg Factor, Dr. Norbert Gleicher explores the science of ovarian aging and what it means for fertility. He discusses why ovarian reserve declines, how age affects egg quality, and emerging research that could change the way we understand reproductive aging.Whether you're trying to conceive, considering fertility preservation, or simply interested in the latest advances
How can the CHR's Second Opinion Program benefit you?
In this episode of The Egg Factor, Dr. David Barad explores the CHR's Second Opinion Program and how it helps patients gain a fresh perspective on their fertility care. Learn what the program includes, who can benefit from a second opinion, and how expert review of your medical history and treatment plan may uncover new options and opportunities.Brought to you by the Center for Human Reproduc
Autoimmunity and Implantation Failure
In this episode of The Egg Factor, Dr. Norbert Gleicher explores the complex and relationship between autoimmunity and implantation failure.Drawing on decades of clinical experience and research, Dr. Gleicher discusses how autoimmune conditions may influence endometrial receptivity, embryo implantation, and pregnancy outcomes. He examines the latest scientific evidence, addresses common misconcept
How Does Diminished Ovarian Reserve Affect IVF Protocols?
In this episode of The Egg Factor, Dr. David Barad explains how fertility specialists tailor IVF protocols for patients with diminished ovarian reserve, discussing ovarian response, medication strategies, egg quality versus egg quantity, and what patients can realistically expect. Tune in for an evidence-based conversation that helps demystify one of the most common and challenging fertility diagn
IVM and Early Retrieval
In this episode of The Egg Factor, our very own Dr. Norbert Gleicher and Dr. David Barad are joined by Lab Director Emanuela Molinari to discuss IVM and Early Retrieval. Tune into this episode to learn how retrieving immature eggs earlier in the cycle and maturing them in the lab can offer an alternative to traditional IVF, with potential benefits for certain patients. Brought to you by the Center
How does summer travel affect IVF treatment?
Planning summer travel while undergoing IVF? In this video, Dr. Sonia Gayete-Lafuente explores how travel can impact IVF treatment, including medication schedules, monitoring appointments, stress levels, and overall treatment success. Learn practical tips for traveling safely during IVF and how to coordinate your plans with your fertility clinic.Brought to you by the Center for Human Reproduction
Why Fertility Professionals Should Attend FRMC 2026
In this episode of The Egg Factor, Dr. Sonia Gayete-Lafuente is joined by Lab Director Emanuela Molinari to discuss why fertility professionals should attend the Foundation for Reproductive Medicine Conference (FRMC) 2026. FRMC 2026 is a premier international gathering focused on independent, patient-centered research and innovation in reproductive medicine, taking place on December 4-6 at the Met
Is embryo selection overrated? Rethinking a core IVF concept.
Embryo selection is often viewed as one of the most important factors in IVF success, but is it getting too much credit? In this video, Dr. Sonia Gayete-Lafuente takes a closer look at the science behind embryo selection, its limitations, and other critical factors that influence treatment outcomes. Discover why embryo quality is only part of the fertility equation and how a broader perspective ma
What Standard Fertility Workups Might Miss
In this episode of The Egg Factor, Dr. Norbert Gleicher explores the limitations of conventional fertility workups and discusses the hidden factors that may be overlooked during diagnosis. Drawing on decades of clinical experience, Dr. Gleicher shares insights into complex fertility cases, emerging research, and why a deeper, more individualized approach can make a difference for patients seeking
Egg Quality in PCOS
In this episode of The Egg Factor, Dr. David Barad explores the relationship between egg quality and PCOS. He discusses how hormonal imbalances, inflammation, and metabolic factors associated with PCOS may affect egg development and overall fertility. The conversation covers how patients can better understand their reproductive health and treatment options.Brought to you by the Center for Human Re
Adding Growth Hormone to your Fertility Protocol
In this episode of The Egg Factor, Dr. Norbert Gleicher is joined by Dr. Angie Beltsos to discuss the role of growth hormone in fertility treatment. They explore the science behind adding growth hormone to IVF and other fertility protocols, who may benefit from this approach, current research findings, and key considerations for patients seeking to optimize their chances of success. Tune in for a
Pride Month: Family building options for the LGBTQIA+ Community
In this special Pride Month episode of The Egg Factor, Dr. David Barad discusses the many family-building options available to LGBTQIA+ individuals and couples. From donor sperm and egg donation to gestational surrogacy and fertility preservation, Dr. Barad breaks down the pathways to parenthood. The episode highlights the importance of inclusive care and empowering every person to build the famil
Male Factor Infertility: The Overlooked Reason
Join us on this enlightening episode of The Egg Factor as Dr. Norbert Gleicher and Dr. Pasquale Patrizio explore the often overlooked topic of Male Factor Infertility. In this episode, Dr. Gleicher and Dr. Patrizio break down the common causes of male infertility, how it’s diagnosed, available treatments, and the importance of education around men’s reproductive health.Brought to you by the Center
Why One-Size-Fits-All IVF Protocols Don't Work
In this episode of The Egg Factor, Dr. Norbert Gleicher discusses why fertility treatment should not be one-size-fits-all. From age and ovarian reserve to underlying health and reproductive history, he explains how individualized IVF approaches can improve outcomes and better support each patient’s unique fertility journey.Brought to you by the Center for Human Reproduction (CHR) on the Upper East
Why Normal Embryos Don't Always Lead To Pregnancy
Why don't normal embryos always lead to pregnancy? In this episode, Dr. Norbert Gleicher explores the complex factors behind embryo implantation failure, from uterine environment and immune factors to embryo biology beyond genetics. Tune in for a discussion on why “normal” embryos can still face challenges and what it means for IVF patients and treatment outcomes.Brought to you by the Center
IVF for Single Women by Choice
Studies show that single women busy with their professional or other personal life projects often delay fertility conversations or even may feel more stress around starting those conversations. In this video, Dr. Sonia Gayete-Lafuente talks about breaking this pattern. She talks about how women don't need a partner to start tackling their fertility goals. Brought to you by the Center for Huma
The Timing of Egg Retrieval and Embryo Transfer
In this episode, Dr. Norbert Gleicher talks about the two most important issues in IVF that clinics often overlook: the timing of egg retrieval and embryo transfer. He explains how even small differences in timing can significantly impact outcomes, and why a more personalized approach is essential. Drawing on decades of clinical experience and research, Dr. Gleicher challenges conventional protoco
Introducing Dr. Sonia Gayete-Lafuente
We’re pleased to introduce Dr. Sonia Gayete-Lafuente, who has officially joined the team at the Center for Human Reproduction (CHR). Dr. Gayete-Lafuente brings a strong background in both clinical care and academic research, with training and affiliations from leading institutions in Europe and the United States. In this episode, she talks about her educational and research background, as well as
National Infertility Awareness Week - Why we don't believe in unexplained infertility at the CHR
In recognition of National Infertility Awareness Week, Dr. Norbert Gleicher explores a question in reproductive medicine: what is “unexplained infertility” Drawing on decades of clinical experience and research at the CHR, he challenges the conventional diagnosis, arguing that infertility always has an underlying cause if we look closely enough. This episode dives into why CHR rejects the label of
New 2026 Clinical Trials
The Center for Human Reproduction recently launched five new 2026 Clinical Trials, powered by the not-for-profit arm, the Foundation for Reproductive Medicine. These new trials reflect an ongoing mission of always bringing the most advanced science directly to patients and integrating the most innovative approaches in research into our treatments here. Every study presented is already IRB-approved
What is a Chemical Pregnancy?
In this episode of The Egg Factor, Dr. Norbert Gleicher breaks down chemical pregnancies. He discusses what they are, why they happen, and what they may reveal about your fertility and reproductive health. Learn the science behind early pregnancy loss and gain expert insight to better understand this common but often overlooked experience.Brought to you by the Center for Human Reproduction (CHR) o
The Role of the Immune System in Pregnancy
In this episode of The Egg Factor, Dr. Norbert Gleicher unpacks the complex and often overlooked role of the immune system in pregnancy. From implantation to early development, the immune system is very important in achieving pregnancy. Dr. Gleicher explains how immune-related issues can impact fertility and reproductive health, and why understanding these issues is key to more effective and perso
Endometriosis Awareness Month with Dr. Sonia Gayete-Lafuente
Since March is Endometriosis Awareness Month, it’s a good time to shine light on a condition that affects millions of people but is still widely misunderstood. Despite how common endometriosis is, there’s a surprising amount of misinformation surrounding it, not only among the public, but even among many individuals living with it. In this video, Dr. Sonia Gayete-Lafuente breaks down everything yo
Lactation Without Being Pregnant
As we continue to celebrate International Women's Month this March, Dr. Sonia Gayete-Lafuente talks about a powerful and often overlooked aspect of motherhood: lactation without pregnancy. For many women and families, the ability to breastfeed represents far more than nutrition. It’s about bonding, connection, and participation in a deeply meaningful part of early parenthood. The good news? E
What are the common causes of recurrent pregnancy loss?
In this episode of The Egg Factor, Dr. David Barad explores the complex topic of recurrent pregnancy loss. He explains what exactly defines recurrent pregnancy loss and discusses the common causes. Throughout the episode, Dr. Barad breaks down the common causes including genetic abnormalities, uterine structural issues, and hormonal imbalances. He also shares insight into different treatment optio
International Women's Month - Fertility Preservation
As the month of March comes along, we observe International Women’s Day and celebrate International Women’s History Month. At the Center for Human Reproduction, this time of year is especially meaningful. We have always been committed to empowering women through education, science, and personalized reproductive care. Today, more women are taking autonomy over their family building timelines, and t
Egg Quality vs Egg Quantity
In this episode, Dr. David Barad discusses the key differences between egg quality and egg quantity, specifically for women trying to conceive in their 40s. He breaks down how egg quantity refers to the number of eggs remaining in the ovaries, while egg quality relates to the genetic health of those eggs. Dr. Barad also discusses how these changes can affect fertility, miscarriage risk, and IVF tr
PGT-A on Trial Part 2: Groundbreaking Interview with Allison Freeman
This is the second part of our interview, which dives deeper into the topic of PGT-A on Trial with Dr. Norbert Gleicher and Allison Freeman, the lead attorney behind a wave of groundbreaking class-action lawsuits targeting the PGT-A industry. From the misleading marketing claims to the emotional fallout experienced by hundreds of patients, this candid conversation continues to peel back the layers
Egg Donation - Frozen vs Fresh Donor Eggs
In this episode, Dr. Norbert Gleicher dives into the topic of egg donation specifically providing insight into the key differences between using frozen vs fresh donor eggs. With expert clinical experience and an extensive background in research, Dr. Gleicher explains how each option may impact success rates, treatment timing, and overall pregnancy outcomes. If you’re considering egg donation or wa
Impact of Advanced Paternal Age on Sperm Quality and Quantity
In this episode, Dr. Norbert Gleicher talks about the impact of advanced paternal age on sperm quality and quantity. He provides an overview for anyone interested in learning more about male reproductive health and discusses why paternal age can play a role in fertility. The video highlights that fertility is not only a woman’s issue and that male factors are also an important part of the conversa
Advancing the Accuracy of Ovulation Trigger Timing for Highly Individualized Oocyte Retrieval (HIER)
It has been more than 40 years since the first IVF baby was born and today, millions of babies are born using assisted reproductive technology. Throughout the years, new studies and research have been conducted which contributes to the advancement of reproductive medicine. One topic that has become popular is the process of how follicle development is monitored and how to determine the timing of t
AI and Infertility Treatment - How will AI be involved?
In this episode, Dr. Norbert Gleicher discusses artificial intelligence (AI) and infertility treatment. He goes into depth regarding the benefits of AI as well as the limitations. He highlights the importance of understanding when and how to use AI appropriately and effectively in medicine. Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history
PGT-A and PGT-M and PGD, What's the Difference and What Can You Test For
In this video, Dr. Norbert Gleicher explains the key differences between PGT-A, PGT-M, and PGD, which are all types of preimplantation genetic testing that is used by many fertility clinics during IVF. Many patients hear these terms throughout their journey, but are not quite sure what they really mean or when each test is actually helpful. Dr. Gleicher breaks down the science of each of these tes
If you're starting fertility treatment at CHR what should you know?
As we begin a new year, Dr. Norbert Gleicher shares what truly sets CHR apart and what patients can expect when starting treatment with us.CHR is known for working with patients who often need more individualized care, including women over 40, patients with diminished ovarian reserve, repeat IVF failures, and complex medical histories. In this video, Dr. Gleicher explains why CHR does not believe
Reclaiming the Fertility Narrative: You’re Not Starting Over, You’re Starting Forward
The New Year often comes with the phrase “New Year, New You,” but for those navigating fertility challenges, that message can feel disheartening, like you are constantly starting from scratch. In this special New Year’s Day episode, Dr. Norbert Gleicher reframes the conversation: you are not starting over, you are starting forward. Drawing on decades of experience, Dr. Gleicher explains how every
Grief Doesn’t Take a Holiday: Holding Space for Joy and Loss at the Same Time
The holiday season is often described as joyful, but for many navigating infertility or pregnancy loss, it can also be a season of grief. In this episode, Dr. Sonia Gayete explores how joy and loss can exist side by side, and why it is important to create space for both. She shares compassionate insights on honoring grief during the holidays, finding small moments of joy, and giving yourself permi
Protecting Your Peace: How to Set Boundaries and Find Joy on Your Own Terms
Navigating fertility treatment is not just a medical journey—it is an emotional one. In this episode, Dr. David Barad and Dr. Norbert Gleicher talk about the importance of protecting your peace during stressful seasons, including the holidays. They share practical ways to set boundaries, honor your emotions, and redefine joy on your own terms. With their unique blend of medical expertise and compa
IVF with Your Own Eggs After 40: What Clinics Aren’t Telling You
More women are choosing to build families in their 40s, yet pregnancy at this stage brings unique challenges and opportunities. In this episode, Dr. Norbert Gleicher and Dr. David Barad come together to discuss the realities of pregnancy after 40, from fertility and egg quality to the importance of individualized treatment plans. They share what truly matters for success, why age alone should not
“Just Relax” and Other Holiday Triggers: How to Respond, or Not
The holiday season can be especially tough for those facing infertility or loss. In this episode, Dr. Sonia Gayete sits down with a CHR patient to talk about one of the most common and frustrating holiday triggers: the phrase “just relax.” Together, they explore why comments like this miss the mark, how to respond (or not) when family or friends bring them up, and what it means to protect your pea
Low AMH, High Hopes: Understanding DOR and Premature Ovarian Aging
Hearing the words “low AMH” or “diminished ovarian reserve” can feel devastating, but they do not mean the end of your fertility journey. In this episode, Dr. Norbert Gleicher explains what ovarian reserve really means, how diminished ovarian reserve (DOR) and premature ovarian aging (POA) are diagnosed, and why early intervention and individualized care matter. He also shares how research has sha
Pregnant at 40+ with Dr. Gleicher
More women than ever are choosing to build families in their 40s, but pregnancy at this stage comes with unique challenges and opportunities. In this episode, Dr. Norbert Gleicher breaks down what makes pregnancy over 40 different, from fertility and egg quality to emotional resilience and medical care. He explains what matters most for success, how individualized protocols can make a difference,
Inside the Embryo Lab: What Happens to Your Embryos After Retrieval
What happens after egg retrieval? For many patients, this part of the IVF process feels like a mystery. In this episode, Dr. Norbert Gleicher sits down with Dr. Cari Nicholas, CHR’s Embryology Lab Supervisor, to walk through the crucial days after retrieval. From fertilization to embryo development, they explain each step inside the lab, how embryologists make decisions about monitoring and transf
Remembering Them: Creating Rituals and Meaning Around Infant or Pregnancy Loss
Pregnancy and infant loss are often accompanied by silence, yet healing requires space for remembrance. In this episode, Dr. Sonia Gayete explores how rituals, both private and shared, can help families honor their babies and create meaning after loss. From simple acts like lighting a candle to community events and creative expressions, Dr. Gayete shares ways that families can find comfort, connec
Medical Miscarriage: What You’re Not Told About Recurrent Loss and Testing Options
When pregnancy loss happens more than once, it is not "just bad luck." It is a medical condition that deserves answers. In this episode, Dr. Norbert Gleicher explains why recurrent pregnancy loss is often overlooked, what standard care misses, and which diagnostic tests can uncover hidden causes. From immune factors to hormonal imbalances, Dr. Gleicher highlights why a one-size-fits-all
Trying Again After Loss: How to Navigate Fear, Hope, and Healing
Pregnancy loss leaves behind not just grief, but difficult questions about when to try again. In this episode, Dr. David Barad explores the emotional and medical realities of pursuing pregnancy after loss. From navigating fear and uncertainty to holding space for hope, Dr. Barad offers compassionate insight and practical guidance for those considering their next steps on the path to parenthood.Bro
Honoring Grief: What to Say (and What Not to Say) After Pregnancy or Infant Loss
Grief after pregnancy or infant loss is often met with silence or words that miss the mark. In this episode, host Dr. Norbert Gleicher speaks with Dr. Simone Tomasi, consulting psychiatrist at CHR, about the power of language in supporting those who have experienced loss. Together, they explore what to say (and what not to say), how compassion can help families feel seen, and why holding space for
The long-term health effects of PCOS
In this episode, CHR’s physicians take a closer look at the long-term health effects of PCOS and what patients need to know beyond their 20s and 30s.At CHR, we believe in looking beyond short-term fertility treatment. PCOS is a lifelong condition that requires awareness, individualized care, and ongoing support.Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New
Breaking down SART outcomes
Success rates are one of the most common ways fertility clinics are compared—but what do the numbers actually mean?In this episode of The Egg Factor, CHR’s Medical Director Dr. Norbert Gleicher and Associate Medical Director Dr. David Barad break down the latest SART (Society for Assisted Reproductive Technology) outcome data.Together, they unpack:How SART collects and reports IVF outcomes across
The Hormone Reset: Understanding the Endocrine and Immune Shifts of Perimenopause and Their Fertility Implications
As fertility declines with age, it's not just about egg quantity—it's about the entire hormonal and immune environment surrounding the ovaries. In this episode of The Egg Factor, CHR’s physicians break down the nuanced changes that happen in the late 30s and 40s, including shifts in estrogen, testosterone, and DHEA levels—and how these changes impact ovarian function and embryo quality.L
Lean PCOS & Low Androgens: The Overlooked Diagnosis Sabotaging Fertility Over 35
Not all PCOS is created equal. In this solo episode of The Egg Factor, CHR’s Medical Director Dr. Norbert Gleicher dives into one of the most misunderstood—and frequently missed—diagnoses in reproductive medicine: lean PCOS with low androgens, also known as D-phenotype PCOS.Often overlooked because these patients don’t fit the “typical” PCOS profile, women with D-phenotype are usually thin, have r
Nutrition vs. Medication: Can Diet Alone Influence IVF Success in Women Over 40?
In this solo episode of The Egg Factor, Dr. Norbert Gleicher, Medical Director of CHR, unpacks the complex relationship between nutrition, inflammation, insulin resistance, and reproductive outcomes in women over 40. Drawing on decades of clinical and research experience, Dr. Gleicher dives into how specific micronutrients and metabolic factors influence egg quality, implantation, and miscarriage
The Fertility Cliff Reconsidered: What the Data Really Shows for Women 40 and Over
We’ve all heard it: after 40, your chances of conceiving with your own eggs plummet. But is the data behind the so-called "fertility cliff" as clear-cut as it seems?In this episode of The Egg Factor, CHR's Dr. Norbert Gleicher unpacks research, clinical experience, and patient outcomes to challenge the mainstream narrative. He explores how fertility statistics have been widely misin
What Does It Really Mean When Ovaries Age?
We often hear about the biological clock—but what does “ovarian aging” really mean? In this episode of The Egg Factor, Dr. Norbert Gleicher and Dr. David Barad explain the science behind ovarian aging, how it differs from chronological age, and what it means for fertility—especially for women in their late 30s, 40s, or those diagnosed with low ovarian reserve.Brought to you by the Center for Human
Inside the Fertility Lab: What Patients Need to Know About Embryos, Grading, & Genetic Testing
What really happens behind the microscope?In this episode of The Egg Factor, Dr. Norbert Gleicher, Dr. David Barad, and world-renowned embryologist Dr. David Albertini take you inside the fertility lab to demystify some of the most misunderstood parts of the IVF process.They break down:-How embryos are graded—and what those grades actually mean-What exactly about morphology is important-The truth
The Three Person Embryo: Science, Ethics & the FDA Ban
In this episode of The Egg Factor, Dr. Norbert Gleicher, Dr. David Barad, and Dr. David Albertini unpack one of the most controversial topics in reproductive medicine today: Three-Person IVF—also known as mitochondrial replacement therapy.Together, they break down:- What “three-parent embryos” actually are- The science behind mitochondrial transfer- Why this technique is currently banned by the FD
Fertility Q&A: Day 3 FETs & Chromosomal Concerns Over 40 with Dr. David Barad and Dr. Norbert Gleicher
In this listener-driven Q&A episode of The Egg Factor, CHR’s Dr. Norbert Gleicher and Dr. David Barad answer two critical questions from our patient community. First up: If you're doing a Day 3 frozen embryo transfer (FET) and had no choice—should you opt for a medicated or modified natural cycle? Then, the doctors tackle a question that weighs heavily on many: What are the most common ch
Fertility and the Law: What Legislation Really Means for IVF
With headlines swirling about legal threats to IVF and fertility treatment, many patients are left feeling anxious and uncertain. In this episode of The Egg Factor, Dr. Norbert Gleicher and Dr. David Barad break down the recent legislative developments—and what they actually mean for fertility care in the U.S.Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New Y
Nutrition, Egg Quality, and IVF for Women Over 40: A Conversation with Prima Pharmacy
If you’ve been through multiple IVF cycles without answers—or you’re over 40 and feeling dismissed—this episode is for you.In this candid conversation with Prima Pharmacy, Dr. Norbert Gleicher, Medical Director at the Center for Human Reproduction (CHR), breaks down what really matters in later-in-life fertility care. From the role of immune health and egg quality to anti-inflammatory diets and th
Redefining the Odds: Fertility Treatment for Women Over 40
In this empowering episode of The Egg Factor, CHR's Dr. Norbert Gleicher and Dr. David Barad discuss why fertility care for women over 40 demands a completely different approach—and how CHR is leading the way. With a mean patient age of 44, CHR has the oldest IVF patient population of any clinic in the U.S., and possibly the world.The doctors share what makes these patients—and their care—so
Breaking Barriers: Fertility Access for HIV+ Patients
In this special Pride Month episode of The Egg Factor, Dr. David Barad and Dr. Norbert Gleicher discuss one of CHR’s proudest milestones: helping HIV+ patients safely and successfully pursue parenthood. Hear the behind-the-scenes story of how CHR helped advocate for a groundbreaking exception to New York State law, allowing HIV-positive individuals to use their sperm in gestational surrogacy.From
Why Is Infertility on the Rise? Unpacking the Trends with CHR Experts
In this episode of The Egg Factor, Dr. Norbert Gleicher and Dr. David Barad of the Center for Human Reproduction dig into the social shifts and biological realities contributing to the global rise in infertility. From delayed parenthood and environmental toxins to male fertility decline and autoimmune conditions, they explore the many layers of a complex issue.Brought to you by the Center for Huma
Male Infertility: The Overlooked Half of the Equation
When it comes to infertility, the focus often falls on women—but nearly 50% of infertility cases involve male factors. In this episode of The Egg Factor, Dr. David Barad and Dr. Norbert Gleicher shine a light on the role of male infertility in reproductive health and why it's time to shift the conversation.Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New
PGT-A on Trial: Groundbreaking Interview with the Lawyer Taking On the Fertility Industry
In this explosive episode of The Egg Factor, CHR’s Dr. Norbert Gleicher sits down with Allison Freeman, the lead attorney behind a wave of groundbreaking class-action lawsuits targeting the PGT-A industry.Allison, a practicing attorney and IVF patient herself, opens up about what pushed her to take legal action against some of the biggest genetic testing labs in reproductive medicine. From the mis
The Emotional Side of Repeat IVF Cycles: Mental Health Awareness with CHR
In this special Mental Health Awareness Month episode of The Egg Factor, Dr. David Barad and Dr. Norbert Gleicher explore the emotional toll of fertility treatment—especially for patients undergoing multiple or back-to-back IVF cycles. At the Center for Human Reproduction (CHR), where many patients come after years of trying or after being turned away elsewhere, the emotional strain is a familiar—
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