Y Combinator Startup Podcast
The Y Combinator Startup Podcast features conversations with Y Combinator partners and founders about building startups. Topics range from the earliest stages of an idea to scaling a company that changes the world. The podcast shares real stories, lessons, and tactics from the frontlines of entrepreneurship.
Episodes
World Models, Explained
Why do even our best AI models need tens of thousands of examples to learn skills that a human picks up in a handful of tries?Solving this problem is one of the great open challenges in modern AI. World models, which give AI an internal simulation of its environment, are one of the most promising paths forward.In this episode of Decoded, YC's Ankit Gupta and Francois Chaubard discuss the intui
How To Better Understand Your Users
Most founders obsess over dashboards and aggregate metrics, but some of the best product insights come from understanding how individual users actually use their product.In this episode of Startup School, YC's David Lieb walks through one of his favorite tools for better understanding your users, the dot plot. It's a simple two-dimensional grid that reveals usage patterns no aggregate char
Why Domain Experts Are Winning In The Age Of AI
Bryant Chou co-founded Webflow, which today powers around 1% of all websites on the internet. Now he's back in the current YC batch with Ploy, an AI-powered website and marketing platform that doesn't just build your site — it connects to your analytics, CRM, and search console to optimize your marketing while you sleep. In this episode of the Lightcone he explains how he built Ploy to be
How To Pick A Startup Idea
Many founders get stuck trying to find the perfect startup idea before they commit. But the perfect idea doesn't exist in the abstract. The only way to find what works is to pick one, go deep, and get feedback from real customers.In this episode of Startup School, YC's Jon Xu breaks down how to choose what to build, "burn the other boats," and go deep enough to practically run yo
"The CEO Must Be the Chief AI Officer"
Brex co-founder and CEO Pedro Franceschi believes most people still underestimate how much AI will change the way companies are built. AI isn't just another tool, it's a new foundation for building products, teams, and companies.In this episode of Lightcone, Pedro shares why he thinks we're only months into a platform shift as significant as the invention of electricity, how AI has cha
How to Build an AI-Native Services Company
Some of the biggest companies of the next decade won't be software businesses, they'll be services companies like insurance carriers, law firms, and tax practices rebuilt from scratch with AI doing most of the work. In this episode of Startup School, YC Visiting Partner Charlie Warren walks through the playbook for building AI native services companies, covering how to pick a market with t
How To Build Superintelligence Inside Your Company
Building superintelligence inside a company isn't about adding AI as a feature. It's about making it the operating system the whole organization runs on. In this episode of the Lightcone, we sat down with YC's Pete Koomen to talk for the first time about how he led the effort to build YC's internal agent infrastructure from the ground up. We cover how giving agents unrestricted acc
How The Best Companies Defend Against Mediocrity And Rot
In this episode of the Main Function Garry sits down with Eric Ries, author of "The Lean Startup", about his new book, "Incorruptible: Why Good Companies Go Bad And How Great Companies Stay Great". Ries breaks down why shareholder primacy often leads to company and product degradation, how founders can lose control of the companies they build, and what legal structures and gove
Paul Graham: Should you move to Silicon Valley?
Paul Graham is a co-founder of Y Combinator. He's funded and mentored companies like Dropbox, Airbnb, DoorDash, and thousands of others through YC, and is one of the most influential voices in the startup world.In this talk at our YC | Stockholm event last month, Paul walks through why ambitious founders should move to Silicon Valley at least briefly, what makes it uniquely valuable — from serendi
Tokenmaxxing: How Top Builders Use AI To Do The Work Of 400 Engineers
We're entering a new era of software where a single person, working with AI agents, can build products that previously required entire teams.In this episode of Lightcone, the hosts break down the rise of AI coding agents, "tokenmaxxing", and the emerging workflows behind tools like Claude Code and OpenClaw. They discuss why AI systems today feel less like productivity tools and more like collabora
Beyond Bigger Models: Recursion As The Next Scaling Law In AI
A 7-million parameter model outperforming models a thousand times its size on tasks like ARC Prize. That's what recursive reasoning unlocks.In this episode of Decoded, YC's Ankit Gupta and Francois Chaubard break down two recent papers on recursive AI models, HRMs and TRMs, that are achieving state-of-the-art results with a fraction of the parameters of today's largest models.They expl
How to Build the Future: Demis Hassabis
Demis Hassabis has had one of the most extraordinary careers in tech. He started as a chess prodigy and video game designer at 17 before getting a PhD in neuroscience and going on to found DeepMind. His lab cracked Go, solved protein structure prediction with AlphaFold, and then gave it away free to every scientist on earth. That work won him the 2024 Nobel Prize in Chemistry. Today he leads Googl
The $9B Startup That Wants to Create a Billion New Developers
Replit is the leading no-code app builder for consumers and enterprise, letting anyone with an idea build real, deployed software using natural language. The company just raised a $400 million Series D at a $9 billion valuation.In this episode of Founder Firesides, co-founder and CEO Amjad Masad sat down with YC's Andrew Miklas to talk about Replit's 10-year journey from browser IDE to vib
The Playbook For Building An AI Native Company
AI isn't just making teams more productive. It's changing how companies should be built.In this episode of Startup School, YC Partner Diana Hu explains what it means to build an AI-native company, where AI isn't just a tool but the operating system your company runs on.She breaks down how to make your company queryable so agents can improve across every function, why management hierarc
Stripe Head of Design Katie Dill Breaks Down Their New Website
Even the most successful websites eventually need a redesign. Take Stripe for example. After six years with the same homepage, they recently unveiled a brand new site that reflects how the fintech giant has evolved over the past few years. So when is the time right for a new landing page? And what should you prioritize in the redesign? In this episode of Design Review YC’s Aaron Epstein sat down S
The GPT Moment for Robotics Is Here
Physical Intelligence is building a foundation model that can control any robot to do any task — what the team describes as the GPT-1 moment for robotics.The company's cross-embodiment approach trains across many different robot platforms, and recent results show tasks being performed zero-shot that last year required hundreds of hours of data collection.In this episode of The Lightcone, co-fo
This Startup Wants To Catch Cancer Before It Spreads
1 in 11 babies born in America this year will be screened by a genetic test that didn't exist a decade ago.Biotech startup BillionToOne turned a simple but radical idea—detecting rare fragments of fetal DNA in a mother's blood—into one of the most widely used prenatal tests in the U.S. And they're not stopping there. The same approach could unlock something even bigger: early-stage can
This Startup Secretly Detects Fraud For Fortune 500s
In this episode of Founder Firesides, YC Managing Partner Jared Friedman talks to Karine Mellata, co-founder of Variance (W23), who is coming out of stealth and announcing their $21 million Series A. Variance builds purpose-built AI agents for risk and compliance — automating fraud detection, content review, and identity verification for Fortune 500 companies and platforms like GoFundMe. They disc
How François Chollet Is Building A New Path To AGI
François Chollet has spent years asking a different question than most of the AI world. Instead of scaling what already works, he’s trying to understand what intelligence actually is—and how to build it from first principles. In this episode of Lightcone, he traces that path from his early work on deep learning to the creation of the ARC prize, and the launch of ARC V3, a new benchmark designed to
Inside The Startup Reinventing America’s Trillion Dollar Chemical Industry
Solugen is reinventing the trillion-dollar chemical manufacturing industry by combining biology and chemistry in a new way. In this episode of Hard Tech, YC's Jared Friedman visits co-founders Gaurab Chakrabarti and Sean Hunt at their Houston HQ to see how they went from a $7,000 PVC reactor to a billion-dollar company competing with industry giants. They cover the breakthrough behind their enzyma
Building A Global AI Startup From India
In this episode of The Lightcone, we talk with Mukund and Madhav Jha, the founders of Emergent - an AI platform that lets anyone build and ship production-ready software. In just eight months, users have created more than 7 million apps on Emergent, with the number doubling in just the last 45 days. We discuss how they built one of the most powerful AI coding agents, why they focused on non-techni
The Future Of Brain-Computer Interfaces with Science's Max Hodak
YC alum Max Hodak is the co-founder of Neuralink and founder of Science, a company building brain-computer interfaces that can restore sight.Science has developed a tiny retinal implant that stimulates cells in the eye to help blind patients see again. More than 40 patients have already received the treatment in clinical trials, including one who recently read a full novel for the first time in ov
How To Avoid AI Design Slop
As no-code design tools become more common, so do the pitfalls. You know what they look like - the purple gradients, annoying hover effects, sections that fade as you scroll. So how do you avoid a site that feels vibe coded while still taking advantage of these new tools? In this episode of Design Review, YC’s Aaron Epstein is joined by Visiting Partner Raphael Schaad, the founder and designer of
The Fastest Path To Super Intelligence
Poetiq is a new startup founded by former DeepMind researchers that recently achieved a major jump on the ARC-AGI and Humanity's Last Exam benchmark by layering a recursive self-improvement system on top of existing models. In this episode of Lightcone, Poetiq's Founder & CEO Ian Fischer joined us to discuss how small teams can build “reasoning harnesses” that outperform base models, w
The AI Agent Economy Is Here
With the takeoff of OpenClaw and MoltBook, a new agent-driven economy is taking shape.In this episode of the Lightcone, we took a look at the explosive growth of AI dev tools and whether the time has come for builders to make something agents want.
Inside Claude Code With Its Creator Boris Cherny
A very special guest on this episode of the Lightcone! Boris Cherny, the creator of Claude Code, sits down to share the incredible journey of developing one of the most transformative coding tools of the AI era.
The New Way To Build A Startup
In the AI era, startups aren't winning by hiring faster — they're winning by automating as many internal functions as possible. In this episode of Main Function, Garry breaks down how tiny teams are beating companies 20x their size by building automations into every workflow, from engineering to ops to customer support.
OpenClaw And The Future Of Personal AI Agents
You’ve probably already heard all about OpenClaw (formerly Clawdbot/Moltbot). The viral sensation is an open-source AI assistant that runs on your own device, connects with messaging apps you already use, and goes beyond chat to actually execute tasks like managing your email, calendars, files, workflows, and more. Now meet the man behind it. YC’s Raphael Schaad sat down with Peter Steinberger, th
We're All Addicted To Claude Code
Wondering why your maker-turned-manager suddenly seems distracted in meetings? Maybe they're addicted to coding agents! In this episode of Lightcone, Calvin French-Owen — a co-founder of Segment and former engineer on OpenAI's Codex team — joins us to talk about why coding agents suddenly feel so powerful, the differences between Codex, Claude Code, and Cursor, and what the future of work
How To Get Your First Customers
When you're starting out, it isn’t enough to just build a minimum viable product. You also need a minimum evolvable product - one that can adapt to the needs of those critical early customers. In this episode of Main Function, YC General Partner Ankit Gupta offers an update to the classic MVP playbook. He’ll outline strategies for getting your first customers, the power of adaptability and how fee
Inside The Startup Building Reusable Rockets
Stoke Space is racing to build the world's first fully reusable rockets that can launch, survive reentry, and fly again and again. In this episode of Hard Tech, YC’s Aaron Epstein sits down with Stoke Space co-founders Andy Lapsa and Tom Feldman to find out why they chose to take on one of the hardest problems in rocket science, how an obsession with efficiency gives them an edge, and what ful
What Surprised Us Most In 2025
2025 was the year AI stopped feeling chaotic and started feeling buildable. In this Lightcone episode, the YC partners break down the surprises of the year, from shifting model dominance to why the real opportunity is moving back to the application layer, and why the next wave of AI startups may be just getting started.
How Intelligent Is AI, Really?
ARC-AGI is redefining how to measure progress on the path to AGI - focusing on reasoning, generalization, and adaptability instead of memorization or scale.During this month's NeurIPS 2025 conference, YC's Diana Hu sat down with ARC Prize Foundation President Greg Kamradt to find out why most AI benchmarks fail, how ARC-AGI reveals the limits of today’s models, and why measuring intelligen
The End of the Designer–Engineer Divide
Head of Design Ryo Lu helped transform Cursor from a feature-layer on top of VS Code into one of the world's leading AI code editors.He joins YC's Aaron Epstein on Design Review to talk about the path that brought him to Cursor, how rapid prototyping reshaped the core product and how he's breaking down the barriers that once separated designers and coders.
From Pivot Hell To $1.4 Billion Unicorn
In just a few years, James Hawkins took PostHog from an idea hacked together right before YC's W20 deadline to a unicorn powering product analytics for thousands of teams.He joins YC's Brad Flora to talk about surviving six months of "pivot hell," why open-source analytics was the breakthrough, and how PostHog grew from fighting for its first users to launching full product lines
The Best Consumer Startup Ideas Were "Impossible" Until Now
Every major shift in consumer tech has a moment when it suddenly becomes accessible to millions. Michael Mignano helped spark one of those moments with Anchor, making podcast creation something anyone could do with a tap. Now at Lightspeed, he sees AI bringing a similar leap to music, media, and everyday apps.In this conversation, he and Garry trace the arc from the early days of social audio to t
Cursor Head of Design Reviews Startup Websites
Cursor Head of Design Ryo Lu has spent his career at the intersection of design and engineering—from building fan sites as a kid to designing products at Stripe, Asana, and Notion. Now he's rethinking how software itself gets made.On this episode of Design Review, Ryo joins YC's Aaron Epstein to break down how great product websites communicate what a company does. They walk through sites
Inside The Startup Launching AI Into Space
Starcloud recently made history by launching a satellite with an NVIDIA H100 into orbit — the first time a GPU that powerful has ever operated in space. It's the first step toward building AI data centers in orbit, powered by continuous sunlight and cooled by radiating heat into deep space.Their approach could one day rival the world's biggest data centers while using less energy, zero fre
How To Recruit The Best Engineers And Sales Reps
Most founders think hiring is about interviewing. But it's actually about selling.For Startup School, Juicebox co-founder & CEO David Paffenholz joins YC's Harj Taggar to share how early-stage founders can find, pitch, and close top engineering and sales talent— from crafting better outreach to winning great hires from Big Tech— even when you're an unknown startup.
From Idea to $650M Exit: Lessons in Building AI Startups
Jake Heller is the co-founder & CEO of Casetext, the AI legal startup behind CoCounsel, which was acquired by Thomson Reuters for $650 million.In his talk at AI Startup School on June 17th, 2025, he shared how his team did it—from picking the right idea to building AI products that actually work—and how founders can turn a cool demo into a reliable tool used by real customers.
Transformers: The Discovery That Sparked the AI Revolution
Nearly every modern AI model, from ChatGPT and Claude to Gemini and Grok, is built on the same foundation: the Transformer.In this video, YC's Ankit Gupta traces how AI learned to understand language — from early RNNs and LSTMs to attention mechanisms and the breakthrough 2017 paper Attention Is All You Need — the discovery that unlocked the modern AI era.
YC Partners Answer Your Questions | Office Hours
Every founder faces moments where they’re not sure what to do next — such as how to go to market with AI products, when to pivot, and who/when to hire.In this episode of Office Hours, YC partners Pete Koomen, Brad Flora, Nicolas Dessaigne, and Gustaf Alströmer answer real questions from founders and share stories about how great teams build conviction, learn faster, and make better decisions as th
What Everyone Is Getting Wrong About AI And Jobs
For years, we've heard two major narratives about AI. One predicting the end of human work, the other dismissing it as hype. The truth is more nuanced, and more hopeful.From radiology to software engineering, the pattern repeats: as technology makes tasks cheaper and faster, demand for human creativity and judgment grows.YC's Garry Tan explores what history, economics, and real companies s
How To Design Products That Truly Stand Out
Karri Saarinen is the co-founder and CEO of Linear, the issue tracking tool used by thousands of high-growth companies. Before Linear, he was the first designer at Coinbase and later a lead designer at Airbnb.On Design Review with YC's Aaron Epstein, Karri shares how his design background shaped Linear’s product philosophy, why quality and craft matter from day one, what founders should look f
The World's First Commercial Mobile Carbon Capture Device
Paul Gross and his team at Remora are trying to do something that’s never been done before.They're building mobile carbon capture devices for commercial trucks and trains—capturing CO2 from moving vehicles before it enters the atmosphere, then turning those emissions into revenue by selling it to customers that can turn the liquified CO2 into new products.In this episode of Hard Tech, YC's
Every AI Founder Should Be Asking These Questions
Jordan Fisher is the co-founder & CEO of Standard AI and now leads an AI alignment research team at Anthropic. In his talk at AI Startup School on June 17th, 2025, he frames the future of startups through questions rather than answers—asking how founders should navigate a world where AGI may be just a few years away.He surfaces the big questions startups should be asking in the age of AGI: Sho
Anthropic Head of Pretraining on Scaling Laws, Compute, and the Future of AI
Ever wonder what it actually takes to train a frontier AI model?YC General Partner Ankit Gupta sits down with Nick Joseph, Anthropic's Head of Pre-training, to explore the engineering challenges behind training Claude—from managing thousands of GPUs and debugging cursed bugs to balancing compute between pre-training and RL. We cover scaling laws, data strategies, team composition, and why the
Fintech 3.0: Now Is The Best Time To Build In Crypto
We are entering the era of Fintech 3.0. Regulatory clarity, growing consumer adoption, and low-cost chains have paved the way for a golden age of building in crypto — and at YC, Base, and Coinbase we want to fund builders to seize this moment. In this episode of Main Function, YC's Harj Taggar and Base's Jesse Pollak sat down to discuss what kinds of companies they're most excited to s
Aaron Levie: Why Startups Win In The AI Era
For nearly two decades, Box co-founder and CEO Aaron Levie has been at the frontlines of how technology reshapes work—guiding the company through the rise of mobile, the cloud, and now the age of AI.In his fireside with YC General Partner David Lieb at AI Startup School, Aaron reflects on what it means to adapt a company over the long term, the hard lessons of staying relevant across multiple tech
The Future of Software Creation with Replit CEO Amjad Masad
Amjad Masad is the co-founder & CEO of Replit, now valued at $3B after a recent $250M Series C. He's spent nearly a decade making programming accessible to all—and with the rise of AI, that vision is closer than ever.In this talk from AI Startup School on June 17, 2025, Amjad traces the arc of computing from mainframes to personal computers to a future where AI agents can create software o
The FDE Playbook for AI Startups with Bob McGrew
Bob McGrew helped build some of the most influential technologies of the past two decades. Bob was an early engineer at PayPal, an early executive at Palantir, and was recently Chief Research Officer at OpenAI - where he led the development of ChatGPT, GPT-4 and the o1 reasoning model.During his time at Palantir, he was a pioneer of the Forward Deployed Engineer (FDE) model, a strategy that is at
Michael Truell: Building Cursor at 23, Taking on GitHub Copilot, and Advice to Engineering Students
Michael Truell on June 17th, 2025 at AI Startup School in San Francisco.At 25, Michael Truell has already built Cursor into one of the fastest-growing companies in AI coding, hitting $100M ARR in just a year. In this fireside chat with YC General Partner Diana Hu, he shares the lessons that came from years of failed projects with his co-founders, why he believes programming is still essential even
GPT-OSS vs. Qwen vs. Deepseek: Comparing Open Source LLM Architectures
OpenAI recently released its first open-weights model since GPT-2, entering a field led by DeepSeek and Alibaba's Qwen.YC's Ankit Gupta breaks down everything you need to know about these top OSS models, including what sets them apart under the hood. He’ll compare their approaches to mixture-of-experts, long-context training, and post-training techniques that shape reasoning and alignment—
How This 25-Year-Old Built A $675M Legal AI Startup (With No Legal Experience)
In this episode of Founder Firesides, YC General Partner Gustaf Alströmer is joined by Max Junestrand, co-founder and CEO of Legora, one of the fastest-growing legal AI startups in the world. In just 13 months, Max and his team scaled from 10 to 100 people, raised $80M, and cracked the challenge of selling to one of the most skeptical industries. Max shares insights on building a successful vertic
The Sales Playbook for Founders | Startup School
Navigating B2B sales for the first time can feel slow and overwhelming.Drawing from his experience founding Monzo and GoCardless, YC's Tom Blomfield shares his playbook for running a tight sales process that lands real, recurring revenue. He walks through each step—free and paid pilots, opt-out contracts, long-term deals—and shows how to prove value and close customers.
Figma CEO Dylan Field: How AI Will Transform Design
Dylan Field on June 17th, 2025 at AI Startup School in San Francisco.Dylan Field co-founded Figma to bring the design process online and make it multiplayer. From a meme maker built on WebGL to a design platform powering millions, Figma’s journey hit a major milestone with its IPO last week.In this conversation, Dylan shares the early challenges of building in the browser, the early risks and pivo
The Finance Startup Bringing Agentic AI to Wall Street
Brothers Chaz and Arnie Englander started Model ML after building and selling two YC companies. What began as a tool to help them analyze deals has grown into a full AI-powered workspace purpose-built for financial services, empowering firms to create automations and workflows that reflect exactly how their teams operate. And it's already being used by 10% of the world's top investment ban
Scaling and the Road to Human-Level AI | Anthropic Co-founder Jared Kaplan
Jared Kaplan on June 16th, 2025 at AI Startup School in San Francisco.Jared Kaplan started out as a theoretical physicist chasing questions about the universe. Then he helped uncover one of AI’s most surprising truths: that intelligence scales in a predictable, almost physical way.That insight became foundational to the modern era of large language models—and led him to co-found Anthropic.In this
Brand Design Tips From Linear Founder Karri Saarinen
For this episode of Design Review, YC’s Aaron Epstein is joined by Karri Saarinen, co-founder & CEO of Linear, one of the top designer-founders working today. Together, they'll review several sites from the YC community with an eye for how to build and maintain a high-quality brand.Thank you to these companies for volunteering to have their sites reviewed*:Sprites AI (https://www.sprites.ai)Gi
Chelsea Finn: Building Robots That Can Do Anything
Chelsea Finn on June 17th, 2025 at AI Startup School in San Francisco.From MIT through her PhD at Berkeley, where she pioneered meta‑learning methods, and Google Brain, Chelsea Finn has built her career around teaching machines how to learn. Now an Assistant Professor at Stanford and co‑founder of Physical Intelligence, she’s using that foundation to bring learning-driven robotics into messy, real
Replit CEO Amjad Masad: Coding Agents, Autonomy, and the Future of Work
Amjad Masad started Replit to make programming accessible to anyone, anywhere. What began as a tool for learning to code has grown into a platform pushing the limits of AI-assisted software creation and recently surpassed $100M in ARR.On The Breakdown with Tom and Dave, Amjad shares the journey from his early days in Jordan, working on open-source projects, to leading Replit through major pivots f
John Jumper: AlphaFold and the Future of Science
John Jumper on June 16, 2025 at AI Startup School in San Francisco.John Jumper is a physicist-turned-computational biologist who led DeepMind’s AlphaFold team—and earned the 2024 Nobel Prize in Chemistry for solving protein folding, a decades-old scientific challenge. In this talk, he shares how a deep learning breakthrough at CASP14 turned into AlphaFold 1 and then AlphaFold 2, delivering atomic
Aravind Srinivas: The Race to Build the AI Browser of the Future
Aravind Srinivas on June 16, 2025 at AI Startup School in San Francisco.Aravind Srinivas started Perplexity with one goal: to rethink how we search, browse, and interact with information online. In this conversation, he shares the journey from hacking together a natural-language-to-SQL search tool to building a product used by millions around the world.He talks about the big bet on the AI-powered
Andrew Ng: Building Faster with AI
Andrew Ng on June 16, 2025 at AI Startup School in San Francisco.Andrew Ng has helped shape some of the most influential movements in modern AI—from online education to deep learning to AI entrepreneurship. In this talk, he shares what he’s learning now: why execution speed matters more than ever, how agentic workflows are changing what startups can build, and why concreteness beats vagueness when
François Chollet: The ARC Prize & How We Get to AGI
François Chollet on June 16, 2025 at AI Startup School in San Francisco.François Chollet is a leading voice in AI. He's the creator of the Keras library, author of Deep Learning with Python, and the founder of the ARC Prize, a global competition aimed at measuring true general intelligence.He's spent years thinking deeply about what intelligence actually is—and why scaling up today’s AI mo
Fei-Fei Li: Spatial Intelligence is the Next Frontier in AI
A fireside with Dr. Fei-Fei Li on June 16, 2025 at AI Startup School in San Francisco.Dr. Fei-Fei Li is often called the godmother of AI—and for good reason. Before the world had AI as we know it, she was helping build the foundation.In this fireside, she recounts the creation of ImageNet, a project that helped ignite the deep learning revolution by providing the data backbone modern computer visi
Legendary Consumer VC Predicts The Future Of AI Products
Kirsten Green, founder of Forerunner Ventures, has backed some of the most iconic consumer brands of the past two decades — from Warby Parker to Chime to Dollar Shave Club. In this conversation with Garry, she shares how great products (not marketing tricks) still win, why AI is unlocking a new kind of emotional relationship between consumers and technology, and what founders can learn from the me
Satya Nadella: Microsoft's AI Bets, Hyperscaling, Quantum Computing Breakthroughs
A fireside with Satya Nadella on June 17, 2025 at AI Startup School in San Francisco.Satya Nadella started at Microsoft in 1992 as an engineer. Three decades later, he’s now Chairman & CEO, navigating the company through one of the most profound technological shifts yet: the rise of AI.In this conversation, he shares how Microsoft is thinking about this moment— from the infrastructure needed t
Sam Altman: The Future of OpenAI, ChatGPT's Origins, and Building AI Hardware
A fireside with Sam Altman at AI Startup School in San Francisco.Sam Altman grew up obsessed with technology, broke into the Stanford mainframe as a kid, and dropped out to start his first company before turning 20.In this conversation, he traces the path from early startup struggles to building OpenAI—sharing what he’s learned about ambition, the weight of responsibility, and how to keep building
Elon Musk: Digital Superintelligence, Multiplanetary Life, How to Be Useful
A fireside with Elon Musk at AI Startup School in San Francisco.Before rockets and robots, Elon Musk was drilling holes through his office floor to borrow internet. In this candid talk, he walks through the early days of Zip2, the Falcon 1 launches that nearly ended SpaceX, and the “miracle” of Tesla surviving 2008. He shares the thinking that guided him—building from first principles, doing usefu
Andrej Karpathy: Software Is Changing (Again)
Andrej Karpathy's keynote at AI Startup School in San Francisco.Drawing on his work at Stanford, OpenAI, and Tesla, Andrej sees a shift underway. Software is changing, again. We’ve entered the era of “Software 3.0,” where natural language becomes the new programming interface and models do the rest.He explores what this shift means for developers, users, and the design of software itself— that we'
Cursor CEO: Going Beyond Code, Superintelligent AI Agents And Why Taste Still Matters
Michael Truell, co-founder and CEO of Anysphere, the company behind Cursor, joins Garry to talk about building one of the fastest-growing startups of all time—and why he's betting on a future beyond code. He walks through the early insights that led his team to leave a promising AI-powered CAD project and instead chase a bigger dream: reinventing how software is written. From years of false st
Fusion Energy Is Tech's Next Big Unlock
Fusion may still sound like science fiction— but it might not be for much longer. With AI pushing demand for clean power to new highs, a breakthrough may finally be close.For Decoded, YC General Partner Gustaf Alstromer traces the history of fusion, the physics behind it, and the engineering challenges that stalled it for nearly a century. He also looks at how Helion is approaching the problem dif
AI Apps Are Broken — Here's How To Fix Them
In this episode of The Breakdown, Tom and Dave are joined by fellow YC General Partner Pete Koomen to lay out a new vision for how AI should actually work: not as a chatbot bolted onto legacy software, but as a customizable tool that helps people offload the work they don't want to do. From editable system prompts to agents that act more like collaborators, they dig into what it means to build
How AI Coding Agents Will Change Your Job
Coding agents are no longer a distant idea—they're already starting to reshape how we work.YC's Tom Blomfield and David Lieb discuss how AI coding tools are transforming software development, why small, high-agency teams will be able to do what once took armies of engineers, and why there's never been a better time to start something new. They explore the bigger picture too: a future w
How To Get The Most Out Of Vibe Coding | Startup School
AI can't yet one-shot an entire product—but with the rise of vibe coding, it's getting close. YC's Tom Blomfield has spent the last month building side projects with tools like Claude Code, Windsurf, and Aqua, seeing just how far you can push modern LLMs. From writing full-stack apps to debugging with a single paste of an error message, AI is becoming a legit collaborator in the dev pr
How Zepto Became India’s Fastest Growing Startup
Imagine ordering groceries and having them show up at your doorstep in just 10 minutes. That’s the promise of Zepto, the fastest-growing e-commerce company in India. In this episode of How To Build The Future, Garry sits down with Aadit Palicha, the co-founder and CEO of Zepto, to discuss how they got started in a Whatsapp group, what it’s like going up against incumbents like Amazon and Zomato an
Why America Stopped Innovating - And How We Can Start Again
Not long ago, America led the world in building and innovation. But over the past 50 years, bureaucracy and red tape have made it nearly impossible to get big things done.Still, there’s a growing movement to turn that around — to build faster, smarter, and better than ever before.In this episode of The Main Function, Garry sits down with Atlantic staff writer and Plain English podcast host Derek T
What Founders Can Do To Improve Their Design Game
In this special episode of Design Review, Aaron sits down with Raphael Schaad, the Head of Calendar at Notion to discuss his leap from designer to founder, why illustration is an important first step when building a new product, and what ultimately makes designers uniquely qualified to start a company today.
How to Build the Future: Tony Xu
12 years after starting DoorDash, co-founder & CEO Tony Xu and his employees still do deliveries every year, staying true to their core value: customer obsession.Today, DoorDash is the largest food delivery platform in the US.In this episode of How to Build the Future, Tony explains how their unwavering long-term vision won — helping create a new market while surviving near death and a global
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