The Incubator At The Bench
At the Bench is a podcast series produced by The Incubator and hosted by Dr. Elizabeth Crouch, Dr. David McCulley, and Dr. Misty Good. The show explores the lives and work of neonatal physician scientists, featuring in-depth conversations with neonatologists who pursue discovery science. Each episode examines how these clinicians found their way into research, the scientific questions driving their work, and the challenges of balancing clinical care with laboratory life. It offers insight and perspective for trainees, early-career investigators, and anyone curious about the role of physician scientists in advancing neonatal care.
Episodes
#030 - Hydrogen, Metformin, and the First Two Hours - Rethinking HIE Neuroprotection with Brian Kalish
In this episode, Misty and Betsy sit down with Dr. Brian Kalish, a neonatologist-neuroscientist at Boston Children's Hospital, for a wide-ranging conversation on building a career at the intersection of fetal and neonatal brain injury research. Brian traces his path from public health and pediatric surgery to neuroscience, describes what "technical courage" means in the lab, and sha
#029 - What If Regulatory T Cells Hold the Key to Preterm Birth?
What happens when a mom's immune system loses its tolerance for pregnancy, and a physician-scientist builds an entire lab, and career, around figuring out why? On this episode of At the Bench, hosts Ben Fensterheim and David McCulley sit down with Dr. Jackie Lajiness, a neonatologist and physician-scientist at Indiana University. Dr. Lajiness traces her path from an undergraduate laser spectr
#028 - Can a Dual Career Couple Build One Lab and Two Careers?
What happens when a scientist and a clinician scientist build a lab together, and an entire career, around the same disease? On this episode of At the Bench, Misty Good and Ben Fensterheim sit down with Professors Claudia and Marcel Nold, a husband and wife team running their lab at Monash University and the Hudson Institute. They trace their path from Charles Dinarello's cytokine lab in Denv
#027 - Are We Harming Preterm Kidneys Every Time We Give Gentamicin?
The neonatal kidney is one of the most understudied organs in our field — and yet the drugs we use every day in the NICU may be affecting it in ways we are only beginning to understand. In this episode of At the Bench, Dr. Misty Good and Dr. Betsy Crouch sit down with Dr. Pamela Good, neonatologist and physician scientist at Columbia University, to discuss her groundbreaking research on nephron de
#026 - Exploring Neonatal Platelet Biology (ft Dr. Christopher Thom)
In this episode of At the Bench, Misty Good and David McCulley interview Dr. Christopher Thom, a neonatologist and leader blood lineage development. Dr. Thom discusses his training in hematology research and what inspired him to build an outstanding research program studying platelet biology and how his research is being translated to change transfusion care for patients. The conversation emphasiz
#025 - Can We Predict Which Pregnancies Will Fail Before They Do?
What is actually happening inside the uterus during a threatened pregnancy — and does the timing of infection change everything? In this episode of At the Bench, hosts Ben Fensterheim and Betsy Crouch sit down with Dr. Kristen Noble, assistant professor at Indiana University, to explore her work building a transcriptomic and proteomic atlas of intrauterine immune responses across gestation. Dr. No
#024 - Navigating the Neonatal Immune Landscape: Insights from Dr. Bunmi Olaloye
In this episode of At the Bench, hosts Misty Good and Betsy Crouch welcome Dr. Bunmi Olaloye, a neonatologist and physician scientist at Yale School of Medicine. Dr. Olaloye shares her path from an early interest in engineering to focusing on necrotizing enterocolitis and spontaneous intestinal perforation in preterm infants. She discusses her research into early life immune development using mass
#023 - Innovations in Prenatal Therapies: Insights from Dr. Tippi MacKenzie
In this episode of the Incubator podcast, hosts David McCulley and Betsy Crouch engage with Dr. Tippi MacKenzie, a leading figure in fetal surgery and stem cell research. The conversation explores Dr. MacKenzie's journey from clinician to scientist, the challenges and innovations in fetal surgery, and the future of prenatal therapies. They discuss the importance of collaboration in research,
#022 - Can Stem Cell Therapy Transform Outcomes for Babies with Lung Disease?
In this episode of At the Bench, Misty Good and David McCulley interview Dr. Bernard Thébaud, a neonatologist and leader in lung and pulmonary vascular developmental biology and regenerative medicine. The conversation explores Dr. Thebaud’s journey into research, the importance of mentorship, and the challenges of translating research into clinical practice. They discuss the significance of recogn
#021 - Building Bridges Between the NICU and the Lab with Dr. Eleanor Molloy
In this episode of At the Bench, Betsy Crouch and David McCulley engage in a thought-provoking conversation with Dr. Eleanor Molloy, a neonatologist and physician scientist. They explore Eleanor's journey in neonatology, the importance of inflammation in neonatal health, and the challenges and rewards of conducting research in this field. The discussion also highlights the significance of col
#020 - Dr. AnneMarie Stroustrup on Environmental Exposures, Research Persistence, and Leadership in Neonatology
In this episode of At the Bench, hosts Dr. Misty Good and Dr. Betsy Crouch sit down with Dr. AnneMarie Stroustrup, Chair of Pediatrics at Zucker School of Medicine, Physician-in-Chief at Cohen Children’s Medical Center, and senior vice president of the pediatric service line at Northwell Health.Dr. Stroustrup reflects on her path from early work in biotechnology to training as a neonatologist and
#019 - Genetics and Neonatal Lung Disease: A Conversation with Dr. Jennifer Wambach
In this episode of At-the-Bench, hosts David McCulley and Misty Good interview Dr. Jennifer Wambach, a neonatologist and researcher specializing in rare neonatal lung diseases. Dr. Wambach shares her journey into neonatology, her research on genetic lung diseases, and the importance of mentorship in developing future physician-scientists. The conversation also covers the Undiagnosed Diseases Netwo
#018 - Beyond Dexamethasone: The Future of Immune Therapies in the NICU
In this episode, David McCulley and Betsy Crouch interview Dr. Benjamin Fensterheim, a neonatology physician scientist, who shares his journey through medical training, the inspiration behind his immunology research, and the importance of bridging the gap between basic science and clinical neonatology. The conversation delves into the challenges faced by physician scientists, the evolving landscap
#017 - Following the Why: Building a Career at the Intersection of Science and Care
In this episode of At the Bench, Drs. Misty Good and Betsy Crouch welcome Dr. Amélie Collins, an R01-funded neonatologist and associate professor at Cincinnati Children’s. A classically trained immunologist turned hematopoietic stem cell biologist, Dr. Collins shares her journey from philosophy major at the University of Chicago to leading a research program focused on fetal myelopoiesis in the co
#016 - The Placenta Holds the Answers: A Researcher’s Perspective
In this episode of At The Bench, Drs. Misty Good and Betsy Crouch speak with Dr. Stephanie Gaw, a maternal-fetal medicine specialist at UCSF, about her path to becoming a physician-scientist and her translational research on placental infections. Dr. Gaw shares how early lab experiences, time in the Peace Corps, and a pivot from infectious disease to OB-GYN shaped her focus on maternal immunity an
#015 - Satyan Lakshminrusimha on Science, Mentorship, and Building a Better NICU
In this episode of the Incubator, David McCulley and Misty Good talk with Dr. Satyan Lakshminrusimha, a leading figure in neonatology and physician-scientist who discusses his journey from clinician to researcher, the significance of large animal studies in neonatal care, and the impact of research on clinical guidelines. They explore the importance of mentorship, the challenges of conducting neon
#014 - Understanding Fetal Growth (ft. Dr. Paul Rozance)
In this episode of the Incubator, Dr. Paul Rozance discusses his research on fetal metabolism and growth regulation, emphasizing the role of insulin, glucagon, and placental function in development. He shares insights on how metabolic signals influence fetal growth and how complications like placental insufficiency impact long-term health. The conversation also highlights the challenges of transla
#013 - Cultivating Talent at the Bench with Dr. Phyllis Dennery (Part 1)
Welcome to part one of a special two-part conversation featuring distinguished neonatologist and physician-scientist, Dr. Phyllis A. Dennery. In this “At the Bench” episode, hosts Drs. David McCulley and Misty Good, along with guest co-host Ben Courchia, delve into Dr. Dennery’s remarkable journey—spanning from her early fascination with molecular biology to her influential roles as Chair of Pedia
#012 - Unraveling the Genetic Basis of Diseases and Decoding Life (ft. Dr. Wendy Chung)
In this episode of the Incubator, Betsy Crouch and David McCulley interview Dr. Wendy Chung, a leader in clinical genetics and child health research. They discuss her journey into genomics, the challenges faced in her career as a physician scientist, the importance of early mentorship, and her research interests, particularly in congenital diaphragmatic hernia (CDH). Dr. Chung shares insights on t
#011 - Scaling New Heights: Pulmonary Hypertension, Environmental Exposures, and Resilience with Dr. Judy Aschner
In this episode of the Incubator, hosts Betsy Crouch and David McCulley welcome Dr. Judy Aschner, a prominent neonatologist and physician scientist. Dr. Aschner shares her journey building a research career and emphasizes the importance of mentorship, determination, and collaboration across disciplines. She discusses her personal experiences that shaped her research focus, particularly in pulmonar
#010 - When serendipity drives innovation
In this engaging conversation, Dr. Emin Maltepe shares his journey as a neonatologist and physician scientist, discussing the serendipitous events that shaped his research interests, particularly in hypoxia and drug development for neonatology. He reflects on the importance of mentorship, the challenges of drug development in pediatrics, and the MD-PhD pathway, providing insights into the complexi
#009 - How to Heal the Preemie Brain 🧠
In this episode of the Incubator "At the Bench," we speak with Dr. Eric Benner, a neonatologist and physician-scientist at Duke University. Dr. Benner shares his path from an MD-PhD student with a background in Parkinson’s research to a passionate neonatologist driven by personal experiences in the NICU after his twin sons were born prematurely. He describes how these experiences inspire
#008 - From Skeptic to Scientist, A Conversation with Dr. Augusto Zani
In this episode of the Incubator: At the bench, we talk with, Dr. Augusto Zani, a pediatric surgeon scientist who discusses his work on fetal lung regeneration and the use of stem cell derivatives and extracellular vesicles for diagnostics and therapy. He shares his journey from surgical training to becoming a surgeon scientist and the challenges he faced along the way. Dr. Zani also explains his
#007 - Understanding mechanisms of neonatal pathologies: From Gut to Inflammation
Dr. Steve McElroy, a neonatologist and physician scientist, discusses his research on injury and repair mechanisms in the immature intestine, specifically focusing on necrotizing enterocolitis (NEC) and spontaneous intestinal perforation in premature infants. He shares his journey from initially not wanting to pursue science to becoming a physician scientist, and how mentorship played a crucial ro
#006 - The Importance of Saliva (Ft Dr. Jill Maron)
In this episode of the Incubator "At the Bench," we talk with Dr. Jill Maron, a neonatologist and physician-scientist at Women and Infants Hospital of Rhode Island and Brown University. Join us as we hear Dr. Maron share her journey from medical school to becoming a leading researcher in neonatology. She discusses how her early drive to provide the best patient care evolved into a commit
#005 - Sex Differences in Neonatal Lung Injury (ft. Dr. Krithikia Lingappan)
In this episode of the Incubator, At the bench, we talk with Dr. Krithika Lingappan who is a neonatologist and physician-scientist at the Children’s Hospital of Philadelphia and the University of Pennsylvania. Join us as we hear what inspired Dr. Lingappan to build her cutting-edge research program investigating sex-specific differences in preterm lung disease. She explains that every cell in the
#004 - Understanding Neonatal Brain Injury with Dr. Donna Ferriero
In this episode of “At the Bench” in the Incubator podcast family, Dr. Donna Ferrero discusses her work on therapeutic hypothermia and neonatal brain injuries. She explains the development and implementation of therapeutic hypothermia as a treatment for brain injuries in newborns. Dr. Ferrero also explores the signaling pathways and early markers that can help identify patients who will respond we
#003 - Advancing CDH Research and Care (Ft Dr. David McCulley)
In this episode of “At the Bench”, we are interviewing one of our show’s co-hosts, Dr. David McCulley. David is a neonatologist and developmental biologist at the University of California, San Diego and in this show he talks about what motivated him to build a research program investigating the genetic and developmental mechanisms responsible for congenital diaphragmatic hernia (CDH). David direct
#002 - Becoming a neonatologist-scientist to cure NEC
In this episode of “At the Bench”, we have the privilege of interviewing one of our hosts, Dr. Misty Good. Dr. Good discusses her amazing career journey from learning to pipette water at the beginning of her neonatology fellowship to becoming a multiple R01-funded investigator. She shares how she is inspired every day to improve the care of preterm infants with necrotizing enterocolitis through he
#001 - Insights in Neurovascular Research (ft. Dr. Betsy Crouch)
This week, we start by interviewing Dr. Elizabeth “Betsy” Crouch, a neonatologist, neuroscientist, and vascular biologist at the University of California, San Francisco. Dr. Crouch’s lab takes a “Vascular-centric” perspective to neurodevelopment and studies how the blood vessels in the developing brain and spinal cord impact the growing neural cells, and vice versa. In part, this approach is inspi
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