The Cure Circle
The Cure Circle explores regenerative medicine, cell and gene therapy, and the science of true healing. It features conversations with scientists, clinicians, innovators, and thinkers who are reprogramming biology to treat disease. Designed for doctors, researchers, founders, and curious listeners, each episode offers insight into the future of healthcare.
Episodes
The Future of Diabetic Foot Care: Wound Healing, Remission & Limb Preservation
What does it take to move beyond simply closing a diabetic foot wound and achieve lasting remission? In this episode of The Cure Circle, host Dr. Smita Karpate, MD, speaks with Dr. David G. Armstrong, DPM, PhD, a podiatric surgeon at Keck Medicine of USC and Distinguished Professor of Surgery and Neurological Surgery at the Keck School of Medicine of USC.As a specialist in diabetic foot care, woun
From Science to Access: Building India’s Cell & Gene Therapy Future
What will it take for India to build a cell and gene therapy ecosystem that can compete globally? In Episode 5 of The Cure Circle, host Dr. Smita Karpate, MD, speaks with Dr. Arun Anand, MD, a physician-executive, cell and gene therapy business leader, and nominated expert on the Precision Biotherapeutics Committee, Department of Biotechnology (DBT/BIRAC), Government of India.With more than two de
Why India Loses Top Scientific Talent
What slows cell and gene therapy, biology or systems?In this episode of The Cure Circle, translational immunotherapy researcher Gaurang Telang explains why reproducibility, documentation, and system reliability, not heroics, determine whether CAR-T science reaches patients. A grounded look at what real CGT translation requires.In Episode 4 of The Cure Circle, host Dr. Smita Karpate speaks with Gau
CAR-T Therapy in Multiple Myeloma: From Relapse to Real Hope
In this episode of The Cure Circle, host Dr. Smita Karpate, MD, is joined by Dr. Mallikarjun Kalashetty, DM, Head of Clinical Hematology, Hemato-Oncology, Bone Marrow Transplantation, and Cellular Therapy at Manipal Hospitals, Bengaluru.Multiple myeloma remains one of the most complex and relentless blood cancers, treatable but rarely curable. While modern drug combinations and stem cell transplan
Why CMC and Manufacturing Decide CGT Success
In this episode of The Cure Circle, host Dr. Smita Karpate, MD is joined by Emily Moran, Founder of 3LB Consulting, a global expert at the intersection of cell and gene therapy manufacturing, CMC strategy, and regulatory execution.While cell and gene therapies promise cures once thought impossible, most programs do not fail because of weak science — they fail because execution breaks down. Emily’s
Building Fitter T Cells to Fight Cancer with Prof. Roland Schelker
In the premiere episode of The Cure Circle, host Dr. Smita Karpate speaks with Prof. Roland Schelker, clinician–scientist at the Leibniz Institute for Immunotherapy, whose work sits at the cutting edge of T-cell engineering, CAR-T therapy, and solid tumor immunotherapy.What began as a routine pharma dinner in 2011 where Prof. Schelker first heard about CTLA-4 checkpoint antibodies became the momen
Why The Cure Circle
The Cure Circle is a global dialogue on regenerative medicine, cell and gene therapy, and the science of true healing. Each episode takes you inside the minds of scientists, clinicians, innovators, and thinkers who are not just treating disease; they’re reprogramming biology itself.Go behind the breakthroughs to discover the personal stories, the collaborations, and the courage driving this new er
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