The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey, the Father of Biohacking and creator of Bulletproof Coffee, hosts this masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to upgrade energy, focus, metabolism, and resilience. Guests include world-class scientists, doctors, and innovators discussing mitochondrial health, peptides, hormones, fasting, sleep, and neuroplasticity. The podcast aims to help listeners live longer, stronger, and smarter lives through data-backed human enhancement.
Episodes
I Wasted 10 Years Stuck With Brain Fog Until I Learned This : 1540
Try TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/discount/davetubeTry Suppgrade Labs: https://shopsuppgradelabs.com/Try Longevity Gummies: https://www.timeline.com/partners/dave-aspreyIf you're waking up exhausted, foggy, or inflamed and nothing seems to fix it, the answer might be hiding in your walls. This deep dive walks through how toxic mold and m
Teal Swan - Beyond the Veil of Ego, AI & Wisdom : 1539
Back with another all-time classic. Teal's is one of those episodes I keep going back to because it was just that good. Now more than ever, we need to ask ourselves: what is the role of Ego? Do we need to worry about AI killing us? Is there hope for the future of our species?These are just a few of the big questions you’ll tackle in this enlightening and esoteric episode re-run. I’m joine
How to Hack Your Smell for Memory and Longevity WHILE YOU SLEEEP! : 1538
Dr. Michael Leon on Smell Training, Memory, Sleep, Alzheimer’s Risk, and Brain Longevity Your sense of smell may reveal more about your brain health than you realize, and stimulating it while you sleep may improve memory, sleep quality, and cognitive function. **Visit https://memoryair.com/ and use code DAVE15 for 15% off. **Host Dave Asprey sits do
Josh Duhamel on Nootropics, Peptides, and Testosterone at 53 : 1537
**Visit https://www.gatlan.com/ and use cod ‘DAVE’ to unlock a free consultation!**At 53, Josh Duhamel says he feels better than he did in his 30s. Host Dave Asprey sits down with actor and Gatlan Health founder Josh Duhamel to talk testosterone, peptides, nootropics, brain health, fatherhood, and what it takes to stay strong as you age. Josh shares why he started TRT in his ear
The Peptide Secrets to a Youthful Face : 1536
Carolina Reis de Oliveira on Reversing Skin Age, Menopause, GLP-1 Skin, and the Science of Senescent Cells Your skin is likely biologically older than you are, but new research suggests some of that aging may be reversible. **For Dave’s listeners only, visit oneskin.co/Dave for exclusive early access to the OS-01 Face Rich Cream!**Host Dave Asprey sits down with Carol
What 36 Hours Without Sugar Does to Your Body : 1535
Try TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/discount/davetubeTry Suppgrade Labs: https://shopsuppgradelabs.com/Try Longevity Gummies: https://www.timeline.com/partners/dave-aspreyThis video walks you through the complete biological timeline of a 36-hour sugar fast, from insulin dropping and liver glycogen draining to fat burning, ketone production
New Seafood Superfood, Apple Watch Health Age, Botanical Drugs, Cannabis IQ, and Blueberries : 1534
Sea Squirt Plasmalogens Show Brain And Aging Benefits In Old Mice Aged mice given purified plasmalogen supplements showed better memory performance, healthier synaptic structure, lower neuroinflammation, and increased signaling tied to neurite growth and synapse development, with treated mice even growing thicker, darker, glossier hair. Plasmalogens are specialized lipids concentrate
Everything You Need To Know About Your Poop | Gut Surgeon Explains : 1533
Dr. Karan Rajan on Fiber Fermentation, Sodium Myths, and What Your Poop Reveals About Disease Risk Your poop is more predictive than almost any other health signal, and you are flushing that data away every single day without a second look. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down wit
If I Had To Lose 50 Pounds FAST, I’d Do THIS : 1532
Try TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/discount/davetubeTry Suppgrade Labs: https://shopsuppgradelabs.com/Try Longevity Gummies: https://www.timeline.com/partners/dave-aspreyMost people fail to lose weight because they have a metabolic block nobody told them about. In this video, I’ve shared the three golden rules for losing 50 pounds fast, a
Raw Garlic, Egg Yolks, Heat Strokes, and Melatonin : 1531
Raw Garlic "Ultimate Biohack" Trend Faces Scientific Scrutiny Raw garlic has gone viral as a morning ritual, with fans crushing a clove, mixing it with honey, and crediting it with everything from lower cholesterol and better insulin sensitivity to cleared acne, eliminated brain fog, and colds cured within 24 hours. The biochemistry behind the trend is real: garlic contains no allici
Jenny McCarthy | The 3 Questions You’re NEVER Supposed to Ask : 1530
Jenny McCarthy on Reversing Autism, Healing Mold Toxicity, and the Biohacking Protocol Big Pharma Doesn't Want You to Know Back with another long one! Autism, mold poisoning, and cognitive decline share more root causes than most doctors admit, and this episode hands you the biohacking playbook to reverse all three. Want to try Jenny's makeup and skincare line? Visit https:
3 Longevity Drugs I QUIT (And the 4 I Take Instead) : 1529
The 3 "Longevity Drugs" That Fail the Data, and 4 Repurposed Ones Worth Considering Back with another solo episode, this one on Big Pharma! Metformin, rapamycin, and statins are three of the most trusted names in longevity, and none of them hold up the way you've been told. This episode breaks down the human data behind the drugs everyone assumes are safe, and reveals four less
7 Brain Compounds I Take For Superhuman Focus : 1528
Try TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/discount/davetubeTry Suppgrade Labs: https://shopsuppgradelabs.com/Try Longevity Gummies: https://www.timeline.com/partners/dave-aspreyThe most powerful energy compounds aren't in your local supplement store. They're sitting in Eastern European science, and Thai herbal medicine, completely ignored by an
Change Your Morning, Change Your Life! Hal Elrod : 1527
Starting your weekend off right, with the king of mindset. We had to replay this one because it's too goo not to!Meet a man who makes miracles happen. Today, I’m joined in the studio by Hal Elrod, author of the international bestseller The Miracle Morning and his newest book, The Miracle Equation. After overcoming multiple near-death experiences and financial hardships, Hal channeled his
Learn THIS And You’ll Become Impossible To Trigger : 1526
Jonny Miller on Nervous System Mastery, Grief, and Why High Performers Can't Afford to Stay Stuck in Their Heads Your nervous system is running every decision, relationship, and reaction in your life, and you won't notice how much it's costing you until something breaks. This episode gives you the exact framework for building real nervous system mastery instead of running on au
Jim Kwik: If You're Using AI Like This, You're Killing Your Brain : 1525
Jim Kwik on Memory, AI, and Why Natural Intelligence Beats Artificial Intelligence Your brain is quietly outsourcing itself to AI, and you won't notice until it's gone. This episode gives you the exact framework to use artificial intelligence as a tool for brain optimization instead of a crutch that erodes your memory, focus, and critical thinking. Watch this episode on Yo
The Most Important Longevity Molecule I've Ever Found : 1524
Try TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/discount/davetubeTry Suppgrade Labs: https://shopsuppgradelabs.com/Try Longevity Gummies: https://www.timeline.com/partners/dave-aspreyMost people see the physical decline of aging as an inevitable process that can only be managed with medications, but this video cuts through that assumption by explainin
The Scientist Monk: Gurudev Sri Sri Ravi Shankar : 1523
This Friday, I had to play back an all-time favorite. I was honored and grateful to bring you a conversation that I recorded in person with Gurudev Sri Sri Ravi Shankar at the Art of Living Center in Los Angeles. Gurudev Sri Sri Ravi Shankar is a leader of an international movement with more than 50 million followers who do breathwork every single morning. He has worked for
The Wild New Theory of Cancer (It's GOOD For You?) : 1522
Quantum Scientist Patrick Coles Reveals How Tumors Protect Your Mitochondria From Toxic Overload Cancer might not be the enemy your doctor says it is. What if tumors are actually your body's emergency detox system, built on purpose to protect you from something far more dangerous? Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAsp
Scream Cream and Weekly Injections (Double Episode) | Gabby Reece : 1521
Dave Asprey and Gabby Reece Talk Testosterone Therapy, Scream Cream, Autism as a Superpower, Cancer Protocols, and Surviving Fame in This Double Interview Episode Mega-Episode time! Your hormones might be causing symptoms you've been blaming on aging, stress, or your heart. This double interview episode gives you a real look at biohacking from two diff
It's Weird, But It Turns On Your Anti-Aging Switch : 1520
Save Up To $600: SUNLIGHTEN.COM/DAVETry TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/discount/davetubeTry Suppgrade Labs: https://shopsuppgradelabs.com/Most people see chronic fatigue and brain fog as permanent conditions caused by getting older, but this video cuts through that misconception by explaining that these symptoms are actually the direct re
Depressing Fruit, Vitamin (C)ancer, Sheep Wool, Oral GLP-1s, Endless Exercise, and more : 1519
PhenoNet Cleared By FDA To Begin Phase 3 Trial Of Inhaled Alzheimer's Drug PhenoNet has received FDA clearance to begin a Phase 3 trial of PHENOGENE-1A, an inhaled formulation of cromolyn sodium, an asthma drug with decades of safety data. Unlike most Alzheimer's therapies, which target only APOE4 gene carriers, this ~648-person trial stratifies both carriers and non-carriers by geno
Dave Solo Pod: The Original Smart Drug Masterclass : 1518
Piracetam, Racetams & Nootropics: Dave Asprey on the Original Smart Drug, Brain Optimization and How to Biohack Memory, Focus and Cognitive Decline We're excited to bring you another Dave solo education masterclass, this one breaking down the molecule that started the entire nootropics industry: Racetams Watch this episode on YouTube for the full video experience: 
Steven Greer | UAP’s and Remote Viewing Techniques for Non-Human Life : 1517
UFOs, UAPs, Non-Human Contact & Zero-Point Energy: Dr. Steven Greer on Government Disclosure, Consciousness and the Truth About Extraterrestrial Intelligence Get ready to have your entire understanding of reality challenged. This episode reveals the science behind non-human intelligence contact, the physics of consciousness, and why the bi
300mg Improves Appearance of Wrinkles In 7 Days (Study) : 1516
This video reveals how your skin uses glutathione to defend itself, how Dr. Nayan Patel solved its delivery problem, and why his topical antioxidant serum was clinically shown to improve the appearance of fine lines, wrinkles, and skin tone in just 1 week.You’ll also learn:The molecule (glutathione) behind clinically-backed wrinkle reduction in 7 daysWhy oxidative stress, not just low col
Longevity Music, Anti-Aging Nasal Spray, How To Look 20, and more... : 1515
Subtitle: A Nasal Spray Longevity Screen, Why Less Protein May Age You Better, Cadaver Skin Injectables, Art's Effect on Biological Age, and Which Anti-Aging Interventions Actually Move the Needle Nasal Spray Ingredient Emerges As Unexpected Longevity Candidate In Massive Drug Screen Researchers mapped 2,358 longevity-associated genes across the body's broader protein and s
Here's How You Can Have a 3-hour Orgasm (real!) : 1514
The Orgasm Code: How Pleasure Rewires Your Nervous System for Longevity & Healing | Regena Thomashauer (Mama Gena) Most people think pleasure is a distraction from performance. This episode proves the opposite: your orgasm is a biohacking tool wired directly into your nervous system, your hormones, and your longevity. Watch this episode on YouTube for the full video ex
I Take 150 Pills a Day (But This One Is My Workhorse) | Resbiotic : 1513
The Gut-Lung Axis: The Missing Link in Chronic Inflammation & Aging | Dr. Vivek Lal Your lungs have a microbiome, and almost no one is talking about it. This episode reveals the hidden pathway behind asthma, chronic inflammation, and slow aging, and gives you a science-backed way to biohack your breath from the inside out. Get A generous discount on Resbiotic by going
I Wish I Knew This Anti-Aging Hack Sooner : 1512
There is one molecule your body already makes that helps protect your cells from aging, but your production of it drops as you get older.In this video, I explain why glutathione is known as the body’s master antioxidant and why it plays a critical role in cellular defense, mitochondrial energy, immune regulation, and liver detoxification.You’ll discover why aging is not just your body “we
Chicken Diarrhea, TV Kills You Quicker, CO2 for Health, Deadly Hot Neighborhoods, and more... : 1511
Viagra's Cancer Signal, TV's Toll on Your Brain, Heat and Accelerated Aging, and a New Way to Flush Your Brain Explained Viagra's Active Ingredient May Block Cancer From Spreading A study published in Cancer Research from the Weizmann Institute of Science, in collaboration with Clalit and the U.S. National Cancer Institute, found that sildenafil, the active ingredient in Viagra,
The $18 Million Pills Nobody Can Explain | Igniton : 1510
Inside Igniton: The Quantum Supplement Science Boosting Memory, Sleep, and Longevity There's a subatomic particle most scientists don't even know exists, and one entrepreneur just spent $18 million building a private lab to prove it can upgrade your longevity, focus, and sleep. This episode goes inside the lasers, vacuum chambers, and cold plasma behind the new science of quant
I Grew My Penis 2 Inches (What Works, And What Doesn't) | Alex Tatem : 1509
Urologist Dr. Alex Tatum on Girth Enhancement, Testosterone, and Peptide Therapy Most men will never ask their doctor the questions this episode answers. From safe, non-surgical girth enhancement to daily testosterone dosing to the peptides fighting for FDA access right now, this conversation covers what actually works, what's dangerous, and what your doctor probably won't bring up f
Does This Sleep Fasting Hack Actually Cut Cortisol? : 1508
You’ve probably tried everything to sleep better. Magnesium. Melatonin. Blackout curtains. Maybe even expensive sleep gadgets. But what if the real reason your sleep feels broken has nothing to do with any of those things?In this video, Dave Asprey explains a hidden biological process that controls whether your body stays in stress mode at night… or finally switches into deep recovery mod
Diet Soda Brain Aging, Hidden Heart Attack Risk, New Cholesterol Pill, Lettuce Recall, and more... : 1507
Artificial Sweeteners & Cognitive Decline, Myosteatosis on Coronary CT, Merck's Oral PCSK9 Inhibitor, Cyclospora Outbreak, Gut-Brain Synchronization, and the Banana Smoothie Mistake Explained Artificial Sweeteners Linked To 62% Faster Cognitive Decline In Landmark Brazilian Study A study tracking more than 12,700 adults (average age 52) over eight years found that people con
The Toxin In Your Gut That's Slowly Killing You (here's the fix) : 1506
Fix Leaky Gut, Boost Testosterone & Slash Endotoxins with Spore-Based Probiotics | Kiran KrishnanYour bad gut bacteria might be the reason your testosterone, your immune system, and even your sperm count are struggling, and most probiotics never survive long enough to fix it. This episode reveals which strains actually make it through your stomach acid alive, and what happens once the
The Truth About Visceral Fat vs Subcutaneous Fat | Dr. Sean O’Mara : 1505
Visceral fat, subcutaneous fat, Prenuvo MRI scans, and the truth about belly fat Your gut and your face are telling on you. This episode reveals why the fat under your skin might be protecting you while the fat around your organs is quietly wrecking your metabolism, heart, and longevity, and exactly what to do about the difference. Get $300 off your next Prenuvo MRI scan:
If I Only Had $200 to Reverse My Age... : 1504
Most people think biohacking is only for billionaires with access to expensive machines, private clinics, and million-dollar anti-aging protocols. But the truth is, some of the most powerful upgrades in your biology start with the basic signals your body receives every single day.In this video, Dave Asprey breaks down how to start biohacking with around $200 by focusing on the foundations
The Science And Health Of Community Eating (How Many Times A Week?) : 1503
Shawn Stevenson On The Science of Family Meals, Oxytocin, and LongevityYour dinner table might be the most overlooked biohack in your house. This episode reveals the exact minimum dose of family meals that lowers a child's risk of obesity, the hormone your body releases every time you eat with people you love, and why teaching your kids to cook may protect their metabolism for life.H
Here's Why Your Supplements Don't Seem To Work | Nayan Patel : 1502
Why Oral and IV Glutathione Never Actually Reach Your Cells (The Delivery Breakthrough Changing Everything) Most of the supplements you're taking aren't failing you, they're failing to ever reach the cells that need them, and almost nobody selling them wants you to know that. This episode hands you the delivery breakthrough that actually gets it there. Use code DAVE for a discou
Peter McCullough: Spike Protein Detected 3.6 Years After the Shot (Detox Protocol) : 1501
Cardiologist Dr. Peter McCullough on mRNA Persistence, Nattokinase, and the Fight Over COVID-19 Treatment" Six years after standing before the US Senate and calling out the pandemic response in real time, Dr. Peter McCullough returns with new evidence on where the spike protein came from, how long it persists in the body after infection or vaccinati
This Ancient Hack Reverses Aging In 72 Hours : 1500
A Nobel Prize-winning discovery revealed that your body has a built-in repair system that can help clear out old cellular damage and support healthier aging from the inside out.In this video, Dave Asprey breaks down the strange Japanese breakfast ritual linked to some of the longest-living people on Earth, why modern life can shut down your body’s natural repair mode, and how one specific
Jordan Harbinger: Fight-or-Flight, Two Kidnappings, and the Wallet Ruining Your Spine : 1499
Nervous System Hacking, Willpower vs Habit Systems, Calendar Time Blocking, and the Wallet Posture Fix Damaging Your Spine Most people think surviving a life-threatening situation comes down to luck. Jordan Harbinger did it twice, and what got him out wasn't luck, it was a nervous system he had trained to override panic. This episode breaks down what actually happens in your body dur
The Foods, Drinks, and Daily Habits Wrecking Your Brain (Surprising!) | David Perlmutter : 1498
Neurologist Dr. David Perlmutter Explains Brain Inflammation and Alzheimer's Risk Your brain has its own immune system, and when it turns against you, it becomes the hidden driver behind Alzheimer's, Parkinson's, depression, and even long COVID. This episode hands you the science to recognize it early and reverse it. Get Dr. Perlmutter’s new book Brain Defenders: https://d
The 1910 Secret: How Light Turns Water Into Medicine | Brian Richards : 1497
Near-Infrared Light Therapy & EMF Shielding with SaunaSpace Founder Brian Richards Your mitochondria are starving for a nutrient you've probably never tracked, and it's not a vitamin or a macro. This episode reveals how a forgotten 1910 therapy uses light to physically restructure water inside your cells, unlocking a mechanism for healing, detox, and mitochondria repair that most
I Tried EVERY Legal Focus Drug, Here’s What Actually Works : 1496
Try Danger Creatine: https://dangercoffee.com/products/danger-creatineTry TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/Try Suppgrade Labs: https://shopsuppgradelabs.com/I have spent twenty years and millions of dollars testing every legal focus drug I could get my hands on. In this video, I break down which compounds actually work, which ones are a was
Organic Produce, Exercise vs Income, Cat Parasite, Thorne, Loss of Taste, and more... : 1495
GLP-1 Side Effects, Gut Microbiome & Brain Health, Toxoplasmosis Risks, and the Dirty Dozen Explained Plasma Acetate Emerges As Key Gut-Brain Messenger In Older Adults A study published in Nature Communications examined how gut bacteria relate to plasma acetic acid, a short-chain fatty acid produced when gut microbes ferment fiber, and found that higher acetate levels tracke
90 Days of Full Carnivore: No Plants, No Fiber, Surprising Gut Results | Ben Azadi : 1494
Carnivore Diet, Cholesterol, Gut Bacteria, Microbiome, and Fasting Insulin Results from a 90-Day Self-Experiment What if cutting out fiber entirely actually improved your gut bacteria? This episode breaks down a real 90-day carnivore self-experiment, complete with before and after blood work, stool testing, and continuous glucose data, that cha
Oxytocin: How To Naturally Induce Your MIRACLE Hormone | Anna Cabeca : 1493
Your Hormones Are Killing You: Oxytocin, FSH, and the Anti-Aging Protocol Most Doctors Ignore Your hormones are running your love life, your intuition, your longevity, and your brain, and most doctors are getting it completely wrong. Host Dave Asprey sits down with triple board-certified OBGYN Dr. Anna Cabeca to break down the clinical science of oxytocin, female pleasure, hormonal o
BONUS: The Anti-Aging Molecule Backed by Nobel Prize Research : 1492
You already know something has changed - the energy crashes, the slow recovery, the brain fog that wasn't there ten years ago. Most people assume that's just aging. But it’s NOT. Nobel Prize-winning research has identified a single molecule that controls how fast your body breaks down, and more importantly, exactly why yours is being destroyed faster than it's being rebuilt. The fix isn't
Fish Oil Doesn’t Work? Anti-Aging Butterflies, the Ancient Brain Focus Switch, and the Best Brain Diet : 1491
Fish Oil Supplements And Alzheimer’s-Related Decline A two-year randomized, double-blind, placebo-controlled trial led by researchers at USC tested whether 2,000 mg of DHA fish oil daily could slow Alzheimer’s-related brain changes in 365 adults ages 55–80 who rarely consumed fish and had at least one Alzheimer’s risk factor. Researchers confirmed the supplement reached the brain by
The 'Secret Sauce' To A 10/10 Morning Routine : 1490
Most energy drinks trade your long-term health for a short-term jolt. This episode breaks down a smarter approach to energy, one that builds mitochondria function, supports gut health, stabilizes mood, and helps you sleep better at night, all without the crash -Get 15% off your next order at: https://getmte.com/dave Host Dave Asprey sits down with Jeff Boyd, founder and chairman
The Biohacking Secrets of Dubai | Dr. Elie Abirached : 1489
Longevity, Trauma Recovery, Circadian Health, Ramadan Fasting & Biohacking Your nervous system may be aging you faster than your diet. Learn how childhood programming, stress, sleep, fasting, resilience, and environment shape longevity, healthspan, metabolism, and human performance, and discover why some of the most powerful upgrades for your biology have nothing to do with
It's Weird, But It Turns On Your Body's Anti-Aging Switch Fast : 1487
Try TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/Try Suppgrade Labs: https://shopsuppgradelabs.com/If you're eating clean, taking the right supplements, and still feel exhausted and mentally foggy - the problem isn't your protocol. Your body has a built-in cellular cleanup system that determines whether any of those inputs actually work, and right now
Sugar-Free Backlash, Taurine Fail, Copper Brain Therapy, Childhood Biohacking, Strength Training : 1488
Sugar-Free Diets Disrupted Gut Microbiome and Metabolism A 16-week sucrose-free, low-fat diet study presented at ENDO 2026 found mice developed insulin resistance, impaired glucose tolerance, gut microbiome imbalance, intestinal inflammation, and fatty liver disease signs despite no weight gain or calorie difference. Host Dave Asprey breaks down why eliminating sugar entire
BDNF Superpowers Through MDMA and Ketamine | Dr. Dave Rabin : 1486
Ketamine Therapy, MDMA, Psilocybin, and the Science of Psychedelic Assisted Healing Most people struggling with depression, anxiety, and trauma have never felt safe in their nervous system, and the treatments they have been prescribed are making that worse. This episode breaks down the neuroscience of psychedelic therapy, why ketamine is the safest and most accessible starting point,
The Skin Mistakes That Age You Fast and Kill You Slow | Dr. Michael Christopher : 1485
Skin Cancer Prevention, Anti-Aging Biohacking, and the Melanoma Detection Gap Most dermatologists are missing melanoma, and a board-certified skin cancer specialist explains exactly why, and what to do about it. This episode covers the detection tool that finds 10 times more melanomas, the real truth about sunscreen chemicals, t
Just 1 Gram Activates Your Deep Focus Switch (Take THIS) : 1484
Try TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/Try Suppgrade Labs: https://shopsuppgradelabs.com/Over the last 15 years, I’ve built companies and spent millions testing what actually upgrades human performance, and I can tell you that mental fatigue has absolutely nothing to do with willpower. In this video, I break down the exact neurochemistry of d
World Cup, Sunscreen, Hair Regrowth, Caffeine Chewing Gum, and more... : 1483
Semaglutide Slows Biological Aging A randomized, placebo-controlled study published in Nature Communications found semaglutide slowed biological aging markers by nine percent on the DunedinPACE epigenetic clock in adults living with HIV-associated metabolic disease, with simultaneous improvements across inflammation, heart, kidney, liver, and brain markers. Host Dave Asprey
Brain Fog, Memory Loss, and Alzheimer's Prevention | Dr. Majid Fotuhi : 1482
How to Reverse Cognitive Decline, Grow Your Hippocampus, and Protect Your Brain from Alzheimer's Disease with Nutrition, Exercise, Sleep, and Stress Reduction Your brain is physically shrinking right now, and most people have no idea it's happening. In this episode, you will discover the exact mechanisms behind cognitive decline, why brain fog is always treatable,
The Foods That Starve Cancer | William Li : 1481
Dr. William Li: Eat to Beat Disease, Extend Longevity, and Hack Your Vascular Health Your body already has a built-in cancer defense system, and the foods you eat can rival prescription drugs at activating it. In this episode, you'll discover what 720,000 living centenarians reveal about longevity, why microplastics are reaching your brain through your nose, and how your bl
I Drink Fat To Look Shredded (Lost 100lbs) : 1480
I used to weigh 300 pounds. I tried every restrictive diet, became a vegan, and trained 90 minutes a day for 18 months with absolute zero results. Everything changed when I drank a cup of yak butter tea at 18,300 feet in Tibet. Within 30 seconds, my severe brain fog lifted, and my metabolism completely shifted.In this video, I break down exactly why adding sugar to your morning coffee is
Putin Longevity, Pancreatic Cancer Cure, AI Therapy, GLP-1 Breast Cancer... : 1479
Pancreatic Cancer Halted by Virus Injection Researchers injected an engineered virus directly into pancreatic tumors in three patients — the virus replicated inside malignant cells, triggered an immune response, and stopped tumor growth and spread at an intentionally low early dose. Host Dave Asprey breaks down why oncolytic viruses can do what chemotherapy can't, how the tumor's den
How to Get Microplastics Out of Your Body | Mara Labs : 1478
Sulforaphane, Detox Pathways, and the Science of Microplastic Removal Microplastics are building up inside your brain, blood, and reproductive tissue, and most detox protocols do nothing to remove them. This episode gives you the cellular science behind why toxins accumulate, which three detox pathways control your ability to excrete them, and what the latest research shows
Peptide Power Without Needles: Smarter Dosing for Longevity | Justin Kirkland : 1477
Needle-Free Peptides, US Manufacturing, BPC-157, Thymosin Alpha-1, GLP-1s, Microneedle Patches, and How to Avoid Contaminated Peptides Peptides are one of the most powerful tools in biohacking and anti-aging medicine, and until now, most people couldn't access them safely, legally, or without a needle. This episode changes that. -Watch this episode on YouTube for the f
Brain Fog Starts in Your Feet (Scientifically Proven) : 1476
I lived with severe brain fog for 15 years. I couldn't focus, my words didn't come easily, and I spent a fortune trying to fix it from the top down...little worked until I realized the problem wasn't in my head—it was in my feet.In this video, I break down the scientifically proven connection between your feet, your circulation, and your cognitive decline. We cover how your brain requires
NASCAR Death, Steroid Olympics, Genetic Age Truth, and Gut Depression... : 1475
Enhanced Games Debut in Las Vegas as the First Openly Drug-Enabled "Biohacker Olympics" The inaugural Enhanced Games took place in Las Vegas with more than 40 elite athletes competing openly while using performance-enhancing drugs, a $25 million prize pool, and a $1 million world record bonus on the table. Host Dave Asprey, who serves on the advisory board of the Enhanced Games, brea
Combine Creatine With THIS To Fight The Root Cause of Aging | Andrew Salzman : 1474
How CD38, PARP, and Leaky Gut Are Destroying Your NAD Levels | Dr. Andrew Salzman Your NAD is being drained by two hidden enzymes, your gut may be the starting point of every aging process in your body, and creatine does something to your mitochondria that has nothing to do with muscle. This episode rewrites what you thought you knew about longevity, anti-aging biology, and
The Doctor With Answers To Your Mystery Symptoms | Jessica Peatross : 1473
The Hidden Causes of Brain Fog, Anxiety, and Chronic Illness: Mold, Parasites, Histamine, and Low Cortisol If you're exhausted, inflamed, and can't figure out why, the answer might be hiding in your histamine, your hormones, your home, or something living inside you that your doctor will never test for. Watch this episode on YouTube for the full v
The EXACT Japanese Formula To Live Past 100+ (Simple Steps) : 1471
In this video, I break down the exact biological mechanisms keeping men in Okinawa, Japan, physically dominant and mentally sharp past 100. You don't need million-dollar lab work or intense weight training to reverse your biological age. Instead, these centenarians leverage five specific lifestyle protocols to naturally upgrade their biology. I explain the hard science behind how eating t
This Epic Device Gives You A SUPERBRAIN : 1472
Light Therapy, 40Hz Gamma & Brainwave Entrainment: How BrainTap Resets Sleep, Clears Brain Fog, and Boosts Productivity by 26% Your brain is being starved of the one nutrient it needs most, and it is not a supplement, not a nootropic, not a fasting protocol. It is light, and a 40 hertz flicker delivered at the right frequency can break up amyloid plaque, reset
The Biblical Anti-Aging Fruit That Scientists Are Obsessed With : 1470
The ancient fruit sitting in your grocery store right now outperforms rapamycin, rivals caloric restriction, and triggers a cellular cleanup process that most longevity scientists did not even know existed until a lab changed everything 18 years ago. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Go to timeli
How To Hack Your Brain's Missing Youth Molecule | Molly Maloof : 1469
Your relationships are reshaping your biology in ways that diet and exercise alone cannot fix, and the science behind it will change how you think about longevity, metabolism, and what it actually means to be healthy. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Molly
The 4,000-Year-Old Asian Focus Drug That Is Not A Drug : 1468
Most guys over 40 rely on coffee just to survive the day, completely unaware that they are pushing their brains into a frantic, high-stress state that actually destroys deep focus and accelerates cognitive decline. In this video, I reveal the science behind why caffeine is failing you and introduce you to a 4,000-year-old amino acid used by monks to achieve effortless, sustained attention
Semen Switch, Chewing Gum, Creatine Cheat, Cancer Plants, and Bedtime Risk : 1467
One Creatine Dose Kept Sleep-Deprived Brains 12% Sharper A randomized, double-blind crossover trial kept 29 healthy adults awake for 21 hours straight ... half the time on a single moderate dose of creatine (~14g), half the time on placebo ... and found the creatine group held on to up to 12% more cognitive performance across logic, reaction time, and language processing. Host Dave A
Stop Wasting Your Gym Sweat (40 Minutes of This Wins Every Time) | Will Harlow : 1466
If you're over 50 and still doing cardio to stay healthy, you're wasting your time and may actually be making things worse. This episode breaks down the exact movements, supplements, and anti-aging strategies that build real strength, protect your bones, and extend your longevity without spending hours in the gym. Watch this episode on YouTube for
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The person you love is either raising your hormones or destroying them, and most people have no idea which one is happening to them. John Gray, the author of one of the most beloved relationship books of all time, returns to reveal how your relational environment directly shapes your biology, and what you can do right now to hack it. Watch this episode on YouTube for the full video e
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If you are constantly bloated, fatigued, and feeling heavy, your gut bacteria have taken over. The standard advice is to just stop eating and do a multi-day water fast. But if your gut is already inflamed, a strict zero-calorie fast will actually spike your cortisol, trigger adrenaline crashes, and blow open the tight junctions in your intestinal wall.In this video, I break down the Itali
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Your biological age can drop by over three years in just eight weeks, and the tools to do it are already in your kitchen. This episode breaks down the cutting-edge science of methylation, polyphenols, Yamanaka mimetics, and epigenetic reprogramming that is rewriting what we know about anti-aging, longevity, and human performance. -Watch this episode on YouTube for the
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