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The a16z Show

The a16z Show

Andreessen Horowitz 1000 Episodes Aug 22, 2026

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week.

Episodes

Martin Casado on Where the Value Is Going in AI
Martin Casado on Where the Value Is Going in AI Aug 22, 2026 00:42:01 Martin Casado joins MTS hosts Theo Jaffee and Sophia Dew to unpack where value is actually accruing in AI, why this technology cycle looks fundamentally different from previous waves, and whether the frontier labs will ultimately capture most of the market. Martin explains why AI has turned venture into a scale-up capital game, where small teams can productively deploy extraordinary amounts of mon
Microsoft's Deputy CISO on Securing AI Agents
Microsoft's Deputy CISO on Securing AI Agents Aug 21, 2026 00:25:15 a16z's Joel De La Garza is joined by Aaron Zollman, Deputy CISO at Microsoft Gaming, to discuss how security teams can embrace AI agents without losing control. Aaron shares Microsoft's experience with OpenClaw, from the initial instinct to ban it to figuring out how to make it safe to use. They unpack what agents mean for identity, permissions, containerization, and monitoring, as well as how AI
How Global Networks Are Reshaping Startup Success
How Global Networks Are Reshaping Startup Success Aug 20, 2026 00:45:44 Elena Burger is joined by a16z’s Angela Strange and Gabriel Vasquez to discuss the rise of the "borderless founder": entrepreneurs who bring the networks and insights of their home markets together with the talent, capital, and speed of Silicon Valley to build global companies. Angela and Gabriel trace how a16z's international investing efforts grew from early work in Latin America into a broader
How Whatnot Built a Global Marketplace
How Whatnot Built a Global Marketplace Aug 19, 2026 00:42:39 a16z General Partner David George is joined by Grant LaFontaine, co-founder of Whatnot, to unpack how a marketplace that started with collectibles evolved into one of the world's leading live shopping platforms. Grant traces the company's origins from selling Pokémon cards online as a kid to discovering live commerce by watching Whatnot's earliest customers hack together sales on social media. The
How Do You Defend Against AI That Can Hack?
How Do You Defend Against AI That Can Hack? Aug 18, 2026 00:22:00 a16z's Joel De La Garza is joined by Nick Warner of Neo and Max Pollard of Cotool to discuss what happens when cybersecurity tools built to defend against humans and malware suddenly have to contend with AI agents. As frontier models become more capable of finding and exploiting vulnerabilities, many of the assumptions underlying traditional security are beginning to break. They explore why guardr
Stripe’s AI Strategy: Build More, Not Less
Stripe’s AI Strategy: Build More, Not Less Aug 17, 2026 00:54:36 a16z General Partner David George is joined by Will Gaybrick, President of Product & Business at Stripe, to discuss how AI is changing the way Stripe builds products, organizes teams, and thinks about the future of internet commerce. Stripe has evolved from a payments company into a multi-product financial infrastructure platform, while a new generation of AI companies is growing and monetizing fa
Ben Horowitz and Travis Kalanick on Building Again
Ben Horowitz and Travis Kalanick on Building Again Aug 14, 2026 00:33:37 Ben Horowitz, Travis Kalanick, and Erik Torenberg take the stage at Atoms' launch event for a candid fireside conversation about entrepreneurship, company building, and why Kalanick believes the next industrial revolution will be powered by AI. They revisit pivotal moments from Uber's history, including the decision not to acquire Lyft, lessons from scaling one of the world's fastest-growing compa
The Two Ways to Sell AI: Lighthouse or Landgrab?
The Two Ways to Sell AI: Lighthouse or Landgrab? Aug 13, 2026 00:44:37 Elena Burger is joined by a16z's Andy McCall and Joe Schmidt to break down two very different ways AI startups can go to market: the lighthouse and the landgrab. Should founders win a handful of marquee customers whose credibility unlocks an entire industry, or move quickly across a broad market where the ROI already speaks for itself? Drawing on Joe's Lighthouse or Landgrab framework and Andy's e
Garry Tan on Taste, Agents and Founder Ambition
Garry Tan on Taste, Agents and Founder Ambition Aug 12, 2026 00:52:03 Anish Acharya is joined by Garry Tan, President and CEO of Y Combinator, for a conversation about how AI is rewriting the startup playbook, why founders should be more ambitious than ever, and what two decades of Silicon Valley booms, busts, and missed opportunities have taught Garry about building what's next. Garry reflects on turning down an early opportunity to join Palantir, why chasing what'
The CISO Playbook for AI Agents | Datadog
The CISO Playbook for AI Agents | Datadog Aug 11, 2026 00:22:54 a16z's Joel De La Garza is joined by Emilio Escobar, Chief Information Security Officer at Datadog, to discuss what it takes to secure a company where nearly every employee is using AI and more than 4,000 engineers are working with coding agents. Rather than trying to block new tools, Emilio explains why Datadog chose to embrace AI early and build the security infrastructure needed to use it safel
The Self-Improving Company | Kavak's AI Playbook
The Self-Improving Company | Kavak's AI Playbook Aug 10, 2026 00:37:20 Angela Strange and Gabriel Vasquez are joined by Alejandro Maza Ayala, Chief Product & AI Officer at Kavak, to unpack how the Latin American used-car marketplace rebuilt itself around AI agents, with 96% of customer interactions and 95% of transactions now handled by agents. Alejandro explains why Kavak decided that simply giving employees AI tools wasn't enough, and instead redesigned the company
The Reality of AI-Powered Cyberattacks | Truffle Security & Socket
The Reality of AI-Powered Cyberattacks | Truffle Security & Socket Aug 7, 2026 00:23:51 Joel De La Garza is joined by Dylan Ayrey, co-founder and CEO of Truffle Security, and Feross Aboukhadijeh, founder and CEO of Socket, to discuss one of the biggest shifts happening in cybersecurity: AI models are no longer just finding vulnerabilities—they're exploiting them. As frontier models become increasingly capable of hacking, software security, supply chain attacks, and cyber defense are

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