This Week in Virology
Vincent Racaniello 1 362 episodes Nov 8, 2026
TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.
Episodes
TWiV 1373: Challenging Dengue and RIGging Flu
TWiV explains results of a dengue virus human challenge which reveals that preexisting immunity shapes viral replication and broadly protective responses, and how influenza virus antagonizes self-sensing by RIG-I to enhance viral replication. Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for thi
TWiV 1372: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are cautiously elated by results of election day 2026 on the backdrop of additional measles associated deaths in Wisconsin, Pennsylvania and New York, return of mpox, Chagas disease in Texas, hippopotami dying from anthrax infections, increase in dengue cases in Florida before Dr. Griffin deep dives into recent statistics RSV, in
TWiV 1371: How to Bat Away Marburg Virus
TWiV discusses an outbreak of H5N1 influenza viruses in Utah farmed mink, and divergent species-specific antiviral responses in Marburg virus infected cells from reservoir bats and humans. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV H5N1 influenza virus in
TWiV 1370: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are distressed by the continued upheaval of leadership at the CDC, recent news of H5 highly pathogenic influenza virus found on mink farms in Utah and in the polar bear population of Greenland, continuing spread of dengue virus in Florida and screwworm in the US, the Ebola outbreak in Kenya, identification of cross-reactive T cel
TWiV 1369: Florida Model Makes Measles Great Again
TWiV explains projected effects of removing school-entry vaccination requirements on measles transmission in Florida and evidence that HLA class I escape drives the evolution of SARS-CoV-2 in human populations. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at
TWiV 1368: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are discouraged by the continuous attack on vaccines especially the birth dose of the hepatitis B virus vaccine, effects of the 2026 changes in immunization schedule, the global burden of vaccine preventable diseases including pertussis and measles, expansion of the Bundibugyo ebolavirus outbreak in Kenya, increase in rabies dia
TWiV 1367: Turning Off Hepatitis B Virus Without Cutting its DNA
TWiV explains a study which shows that influenza A virus infection induces immune dysregulation in the placenta and fetus without vertical transmission in nonhuman primates, and development of an epigenetic silencer therapy to transcriptionally inactivate viral DNA in chronic hepatitis B. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts,
TWiV 1366: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are crestfallen to learn of the 6th measles death in Pennsylvania and more than 9000 deaths from Ebola, an enterovirus/Coxsackievirus outbreak at the University of Pennsylvania, decimation of the HIV services following withdrawal of PEPFAR and USAID, role of gut microbes in vaccine adverse events such as fever, continued raw milk
TWiV 1365: Andes Virus Up Close
TWiV travels to Porto, Portugal for the annual meeting of the European Society for Clinical Virology, where he speaks with Catherine and Corinne about their work on the Andes virus outbreak on the MV Hondius. Host: Vincent Racaniello Guests: Catherine Houlihan and Corinne Guerts van Kessel Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support scien
TWiV 1364: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss their continuing struggle to understand the ongoing outbreak of cyclospora, decimation of US public health including 30% or greater loss of personnel from the CDC, continuing measles outbreaks here and aboard, a mumps outbreak in San Diego and a Hib death in Montana, criminalization of pediatricians in Texas, dengue assoc
TWiV 1363: A Cauldron of Bats
TWiV explains a study testing how 16 hypothesized social and environmental drivers impact disease outbreaks, concluding that infectious disease spillover and emergence are multi-causal, and that no one-size-fits-all strategy can prevent epidemics and pandemics, and an analysis of Myotis bats, which shows that their remarkable longevity and immunity are linked through pleiotropic adaptations to vir
TWiV 1362: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello continue their ongoing exasperation over 5 deaths in Pennsylvania associated with measles infections, the absurdity of RFK Jr.'s statement that AI is better informed than physicians, the outbreak of cholera, more deaths by raw milk products, spread of dengue virus in Florida, Ebola in DRC, refusal to acknowledge the benefits of t
TWiV 1361: Ancient Viral Sword and Shield
TWiV explains discovery of a previously unknown mechanism of RNA-guided DNA recognition for genetic control that possibly predates the emergence of CRISPR pathways, and the possibility that Alzheimer's Disease neuropathology evolved as a host defense response to microbial infection in the brain. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email
TWiV 1360: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello frustration continues over the increasing number of measles infections, Kennedy's undermining of vaccines, perpetuation of autism- vaccine, autism-tylenol myths, an outbreak of hepatitis A virus in the US, the Ebola outbreak in Uganda, changes in reporting of virus infection and vaccine recommendations, Legionnaires disease and s
TWiV 1359: SSPE, the Long Shadow of Measles
Roberto Cattaneo and Kalpana Yadav join TWiV at the 2026 meeting of the American Society for Virology to discuss how the absence of measles virus receptors in the brain selects for hyperfusogenic variants that spread neuron-to-neuron and cause subacute sclerosing panencephalitis, a rare but fatal long-term neurological sequela of measles infection. Host: Vincent Racaniello Guests: Roberto Cattane
TWiV 1358: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are angered by the continuous reporting of measles deaths in the US and around the world, the Ebola outbreak in Uganda, changes in reporting of virus infection and vaccine recommendations, establishing an NIH research center on vaccine harms, Legionnaires at Yankee stadium and the first time in more than half a century reporting
TWiV 1357: Furin, Naturally with Paul Bieniasz
Paul Bieniasz joins TWiV to discuss his lab's discovery that the coronavirus nuclease NSP15 cuts viral RNA into oligonucleotides that are reinserted elsewhere in the viral RNA, generating insertion mutations at a frequency above 10⁻³ per genome, including new furin cleavage sites at the spike S1/S2 junction. Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Guest: Paul Bieniasz Subscribe
TWiV 1356: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello delve into dengue virus infections in Florida, recent human rabies infections in the US, proposed changes in biomedical funding including "converting" the Department of War into NIAID, the continuing controversy over the deaths of 2 children in Pennsylvania from measles, before Dr. Griffin deep dives into recent statistics RSV, i
TWiV 1355: Four billion years of AI training data
TWiV reviews a landmark paper reporting the first generative design of complete viral genomes using AI, producing 16 viable bacteriophages that overcame antibiotic-resistant bacteria where natural phages could not, and a study suggesting that recombinant shingles vaccination reduces the risk of cardiovascular events. Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker Subscribe (free):
TWiV 1354: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello remember Dolly Parton and her patronage of science, especially development of the COVID-19 vaccines, if the shingles vaccine protect against cardiovascular events as well as dementia, the continued national cyclosporiasis and screwworm outbreaks, size of the Ebola outbreak in the Congo, the death of 2 children in Pennsylvania fro
TWiV 1353: Phage bet-hedging and EBV antibodies
TWiV explores how bacteriophages enable bet-hedge against bacterial immune defenses, and how transgenic mice engineered to produce human antibodies yielded potent anti-EBV candidates targeting gp350 and gp42, a promising step toward Epstein-Barr therapeutics. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of T
TWiV 1352: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are disheartened by the suggested change in federal vaccine recommendations, how Florida rolled back 4 childhood vaccine school requirements, results from a clinical trial suggesting that IPV can be used for outbreak control in IPV only countries, the continued national cyclosporiasis and screwworm outbreaks, size of the Ebola ou
TWiV 1351: Ebola Virus Brains and Contagious Catfish Cancers
TWiV describes a human cerebral organoid model for Ebola virus persistence, and brown bullhead catfish melanoma, a novel transmissible cancer. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Revamp of how NIH scores research grant proposals (Nature) Kansas BSL
TWiV 1350: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are perplexed by the state of global public health as malaria, cholera and other infectious diseases are spread by civil warfare, the lack of manpower at the CDC to implement Congressional health programs, the first cancer mRNA vaccine resulting from a Merck and Moderna collaboration, how cyclosporiasis and screwworm outbreaks co
TWiV 1349: Smallpox and mummies
TWiV explains how liquid–liquid phase separation and a phage-encoded inhibitor cooperatively drive transcriptional transition during phage SPO1 infection, and the first smallpox virus genomes from an early outbreak in South America. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode
TWiV 1348: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are troubled by the latest executive order changing routine childhood vaccine recommendations, the call for nominations to join the Advisory Committee for Immunization Practices, West Nile virus transmission in South Carolina, a newly identified midge-transmitted virus sickening cattle, and development of a cold-chain free DPT va
TWiV 1347: No Short Answers for Long COVID
TWiV explains research showing that Long COVID is associated with reactivation of numerous chronic viruses, including herpesviruses and anelloviruses, and with the production of autoantibodies that target neurological tissues. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science educa
TWiV 1346: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are distressed by Erica Schwartz' confirmation as CDC director, the GAO proposed pandemic preparedness plans, the national cyclospora outbreak and resulting two deaths, new screwworm and the scale of the Ebola outbreak in the Congo, and clear results from some of President Trump's policies dismantling public health activites incl
TWiV 1345: Rocky Mountain Virology High
TWiV travels to Colorado State University in Ft. Collins, where he speaks with Angela Bosco-Lauth, Rebekah Kading, and Mark Stenglein about their careers and their virology research. Host: Vincent Racaniello Guests: Angela Bosco-Lauth, Rebekah Kading, and Mark Stenglein Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at Micro
TWiV 1344: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss the numerous attempts by states to roll back vaccine laws, the recent surge of Dengue virus cases in Sri Lanka, the national cyclospora outbreak, new screwworm and Legionnaires cases, launching of the CHaT-Ox Ebola vaccine trail, scale of the Ebola outbreak in the Congo and if cross-reactive Ebola antibodies are effective
TWiV 1343: Batting averages and stolen bases
TWiV explains research which shows that Per os infectivity factors are essential for bracovirus infection and wasp parasitism, and that periodic shifts in viral load increase risk of Hendra virus spillover from Pteropus bats. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science educ
TWiV 1342: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello explore the source/not source of the national cyclospora outbreak, trust in the FDA to correctly identify the source, new screwworm, Legionnaires and cyclosporasis cases, the Ebola outbreak in the Congo and development of a novel vaccine and antiviral before Dr. Griffin deep dives into the measles outbreak including the new Penns
TWiV 1341: Phage breaks and COVID origins
TWiV explains research that reveals dual activity of a phage-encoded lysin that modulates infection dynamics in a mycobacteriophage, and refutes a proposed link between the SARS-CoV-2 furin cleavage site and mouse-adapted MERS-coronavirus MA30. Hosts: Vincent Racaniello, Kathy Spindler, Angela Mingarelli, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Link
TWiV 1340: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello debate if Senator Mitch McConnell's recent hospitalization is due to post-polio syndrome or just old age, how air quality from Maine to Chicago has been affected by the Ontario wild fires, new screwworm, Legionnaires and cyclosporasis cases, the Ebola outbreak in the Congo and development of a novel vaccine and antiviral, before
TWiV 1339: Ebola up close with Tom Ksiazek
Tom Ksiazek, a world-renowned virus expert with 40 years of experience on the front lines of some of the worst outbreaks the world has ever seen, joins TWiV to discuss his career, ebolaviruses in general, and the current outbreak of Bundibugyo ebolavirus in Africa. Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker Guest: Tom Ksiazek Subscribe (free): Apple Podcasts, RSS, email Become a p
TWiV 1338: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are dismayed over the military deaths due to the voluntary influenza vaccination policy, FDA's first vaccine recommendations since 2023, the efficacy of influenza vaccines, new screwworm, Legionnaires and cyclosporiasis cases, the Ebola outbreak in the DRC and Uganda and before Dr. Griffin deep dives into the measles outbreak, re
TWiV 1337: The whitefly and the Red Queen
TWiV explains research that reveals an an alternative evolutionary path of antiviral signalling in a sea anemone, and how a bacterial symbiont and a plant virus enhance insect fitness by inducing physical defenses against fungal parasites. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support sci
TWiV 1336: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello lament about the new ACIP charter, how administration of the HPV vaccine has eliminated cervical cancer deaths in young women, the global economic burden of infectious disease, restoring trust in vaccinology, new screwworm cases, the Ebola outbreak in the Congo and Uganda and need for preparedness, before Dr. Griffin deep dives i
TWiV Special: Albert Sabin with Karen Torghele
Vincent speaks with Karen Torghele about her recently published biography of polio vaccine pioneer Albert Sabin, the first ever written. Host: Vincent Racaniello Guest: Karen Torghele Subscribe (free): Apple Podcasts, RSS, email Links for this episode Karen Torghele's website Purchase Albert Sabin by Karen Torghele (Bookshop or Amazon) My letters from Albert Sabin (virology blog) Become a patro
TWiV 1335: TldR, bacterial hot rods and nullifying norovirus
TWiV explains research showing how temperate phages enhance bacterial host fitness via RNA-guided flagellar remodelling, and that IgA antibody is necessary and sufficient to prevent norovirus infection in mice. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science educ
TWiV 1334: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss the global economic burden of infectious disease, restoring trust in vaccinology, the Legionnaires outbreak in Harlem, new screwworm cases, the Ebola outbreak in the Congo and Uganda and an import case into France, end of the hantavirus outbreak before Dr. Griffin deep dives into the measles outbreak, recent statistics RS
TWiV 1334: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss the global economic burden of infectious disease, restoring trust in vaccinology, the Legionnaires outbreak in Harlem, new screwworm cases, the Ebola outbreak in the Congo and Uganda and an import case into France, end of the hantavirus outbreak before Dr. Griffin deep dives into the measles outbreak, recent statistics RS
TWiV 1333: STING like a nanoparticle, float like HIV
TWiV explains research showing how HIV-1 signalling remodels nuclear pores to licence infection, and development of STING agonist nanoparticles to enable coordinated mucosal-systemic immunity for durable pan-β-coronavirus protection. Hosts: VVincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode
TWiV Special: Ebola virus and Andes virus with John Dye
Vincent travels to ASM Microbe in Washington DC to speak with John Dye of the United States Army Medical Research Institute of Infectious Diseases about the recent outbreaks of Bundibugyo ebolavirus in Africa and Andes virus on a cruise ship. Host: Vincent Racaniello Guest: John Dye Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Intro music is by Ronald Jenkees Send your vi
TWiV 1332: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello express concern about vaccine policy and ACIP, scaling back of the CDC's role in global public health, shingles vaccine and dementia, new screwworm cases, the Ebola outbreak in the Congo and Uganda and where the hantavirus outbreak began, before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenz
TWiV 1331: A drug for cervical cancer
TWiV explains research showing that dairy cows are infected with low doses of influenza A(H5N1) and do not transmit efficiently to other animals, and covalent inhibitors of human papillomavirus type 16 E6 protein that restore p53 function and suppress growth of HPV-driven tumors in vivo. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Angela Mingarelli Subscribe (free): Apple Podcasts
TWiV 1330: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello opine on the recent executive order on the routine childhood vaccination schedule, the Ebola outbreak in the Congo and Uganda including the fast track trials for 2 vaccine candidates and antivirals, recent Hantavirus infections, use of quarantined "Hantavirus" patients for the governmental propaganda machine, use of ribavirin and
TWiV 1329: How HIV-1 goes nuclear
TWiV explains research showing limited transmission of cervid prions to nonhuman primates, and the finding that cone-shaped HIV-1 capsids are transported through intact nuclear pores. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld La
TWiV 1328: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello opine on the recent executive order on the routine childhood vaccination schedule, the Ebola outbreak in the Congo and Uganda including the fast track trials for 2 vaccine candidates and antivirals, recent Hantavirus infections, use of quarantined "Hantavirus" patients for the governmental propaganda machine, use of ribavirin and
TWiV 1327: Influenza viruses in the MIST
TWiV explains research on human influenza virus transmission that reveals heterogeneous expulsion of infectious virus into air, and how gut bacteriophages dictate inflammation heterogeneity through tuning the phage-bacteria-sphingosine-intestine axis in Crohn's disease. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a
TWiV 1326: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello comment on incidences of locally transmitted malaria in the US, mpox diagnostics, the latest developments surrounding hantavirus infections, and the Ebola outbreak in the Congo and Uganda including vaccine candidates before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infection
TWiV 1325: Sticky flu with Hannah Rowe
Vincent travels to Oregon State University in Corvallis to meet up with Hannah Rowe to talk about her career and her work demonstrating how the interaction of influenza A virus and Streptococcus pneumonia influences transmission. Hosts: Vincent Racaniello Guest: Hannah Rowe Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at M
TWiV 1324: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss withdrawal of the ACIP charter published in April 2026, the first council meeting on antibiotic resistant bacteria, the latest developments surrounding hantavirus infections, and the Ebola outbreak in the Congo and Uganda before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-Co
TWiV 1323: One influenza infection, two patients
TWiV explains mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines, and how toll-like receptor 7 alters the maternal immune landscape during influenza A infection to increase maternal and fetal morbidity, Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV
TWiV 1322: Clinical update with Dr. Daniel Griffin - Hantavirus special
In his weekly clinical update, Daniel Griffin and Vincent Racaniello reviewed the latest developments surrounding the hantavirus outbreak, including new interim guidance from the Centers for Disease Control and Prevention for the management of infectious cases, whether the CDC may be downplaying the significance of the outbreak because of public backlash following the COVID-19 pandemic, before Dr.
TWiV 1321: Phage cross talk and cross reactions
TWiV explains how cross-reactive anti-prophage antibodies and bacterial heteroresistance is implicated in phage therapeutic failure, and how phages communicate across species to shape microbial ecosystems. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education
TWiV 1320: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the outbreak of Hantavirus on a cruise ship and its potential for person-person transmission, how cessation of funding for global health by the Trump administration has compromised American health and well being, as well as the description of paralytic poliomyelitis outbreaks in Central Africa associated with the administrat
TWiV 1319: An earful of SARS-CoV-2
TWiV explains the emergence of vaccine-derived poliovirus strains from the novel oral polio vaccine in the Central African Republic, and the infection of spiral ganglion neurons in the inner ear by SARS-CoV-2, which may explain hearing loss in humans. Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episo
TWiV 1318: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello note the uncertain future of the National Science Foundation amid shifting U.S. funding priorities and governance; the rise of China as a global research powerhouse; ongoing advances and controversies in vaccines shaped by the World Health Organization and the Centers for Disease Control and Prevention; vaccine policy battles in Flo
TWiV 1317: Dead shrimp walking
TWiV explains a study showing that viral DNA load in blood and saliva varied markedly with age, time of day season, sex, and depended on dozens of genetic loci, and identification of an emerging human eye disease associated with aquatic virus zoonotic infection. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TW
TWiV 1316: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello are distressed by RFK Jr's testimony in front of Congress, surges in rotavirus infections and the staggering number of people who believe in unproven claims about vaccines and science, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashbo
TWiV 1315: Jabs for bats
TWiV explains a study showing that the wildlife trade, including live-animal markets, is a major driver of animal-to-human pathogen transmission, and ecological vaccination, a strategy to prevent zoonotic spillover from bats. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Suppor
TWiV 1314: Clinical update with Dr. Daniel Griffin
TWiV 1314: Clinical update with Dr. Daniel Griffin April 17, 2026 In his weekly clinical update, Dr. Griffin and Vincent Racaniello are dismayed but not surprised by poll results suggesting most Americans doubt vaccine safety, that the head of the CDC and NIH delayed release of a report on the safety of the COVID-19m vaccine, how Nature works to spread disease without the help of the lab and the
TWiV 1313: Maybe they're all dementia vaccines
TWiV reviews evidence that influenza standard and high-dose vaccines reduce risk of Alzheimer's dementia, and spread of deltaviruses by a viral Trojan horse mechanism. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Dennis O'
TWiV 1312: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello are aghast at the CDC's decision to no longer test for rabies and mpox and the revised charter for its the advisory committee on immunization practices, an outbreak of E. coli illness in raw cheese, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwat
TWiV 1311: Jayhawks go viral
Vincent visits the University of Kansas and speaks with Tony Fehr, Robin Orozco, Juergen Richt and Rob Unckless about their careers and the research ongoing in their laboratories. Host: Vincent Racaniello Guests: Tony Fehr, Robin Orozco, Juergen Richt, and Rob Unckless Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at Microb
TWiV 1310: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello cover if the "five-second" rule for things that fall on the floor apply to surgical equipment, an outbreak of E. coli illness caused by raw cheese before Dr. Griffin then deep dives into the measles outbreak in South Carolina and Utah, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns
TWiV 1309: Maybe they're all cancer vaccines
TWiV explains why human papillomavirus vaccine-induced immunity can block infection, unlike all other vaccines, and how respiratory viral infections such as COVID and influenza prime accelerated lung cancer growth. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science educ
TWiV 1308: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the resignation of a member of the advisory committee for immunization practices and the irony of his rationale that a judge slandered him, vaccinating dairy cattle against H5N1, illnesses resulting from drinking raw milk and the US norovirus outbreak, which is not cruise related, then Dr. Griffin deep dives into the meas
TWiV 1307: My heart breaks for flu
TWiV reviews the structural basis for Rep-mediated adeno-associated virus DNA genome packaging, how influenza virus-infected myeloid cells travel to the heart and infect cardiomyocytes, leading to IFN-fueled heart damage. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support
TWiV 1306: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello chat about death of water fowl on Long Island, 'renaming' of the FDA adverse event monitoring system, lawsuits against RFK Jr and HHS for illegal changes in routine immunization practices, before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolina, Utah and ICE detent
TWiV 1305: Lab leak idea called on the carpet
TWiV introduces sunshine virus of carpet pythons and its effect snakes after experimental infection, and development of a new tool to distinguish between naturally ocurring outbreaks and those that arise from lab accidents. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support sci
TWiV 1304: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the global spread of the 'eradicated' poliovirus, the suggestion of RFK's autocratic ability to change vaccine policy and the 'resignation' for the second time of CBER director Vinjay Prasad, and zoonotic spillover of viruses without adaptation, before Dr. Griffin deep dives into economic costs of not vaccinating against mea
TWiV 1303: Overachieving vaccines
TWiV reviews an association between shingles vaccination and slower biological aging, and how mucosal immunization in mice provides protection against disease caused by diverse viruses and bacteria. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at Microbe
TWiV 1302: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the health misconceptions that RFK Jr continues to perpetuate and how to combat them, first cases of highly pathogenic influenza in the California elephant seal population before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolinaand Utah, ICE detention cen
TWiV 1301: Lost in giant virus translation
TWiV reviews lymphocytic choriomeningitis virus seroprevalence among urban pregnant women and newborns in Philadelphia, and a functional translation initiation complex encoded in the genome of giant viruses that drives synthesis of viral structural proteins. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron o
TWiV 1300: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss several states and the governor of Pennsylvania suing HHS over changes in the childhood vaccination schedule, the vaccine derived type 2 poliovirus outbreak in Pakistan and implications for the global withdrawal of the oral poliovirus vaccine, and the outbreak of Candida, then Dr. Griffin deep dives into recent statistics RS
TWiV 1299: Moth balls and blood clots
TWiV explains how vaccine-induced thrombotic thrombocytopenia develops from antibodies to adenovirus and somatic hypermutation, and castration by a viral protein tyrosine phosphatase that targets a host cell cycle checkpoint protein. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode S
TWiV 1298: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss reversal of last week's no review decision on a flu mRNA vaccine by Vinjay Prasad, appointment of Jay Bhattacharya as CDC director, no experience required, and already detectable reduction in hepatitis B virus vaccination rates, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infectio
TWiV 1297: Spillover squirrel
TWiV explains the observation that filamentous virions act as non-infectious interfering particles to modulate papillomavirus infection, and transmission of monkeypox virus from fire-footed rope squirrels to sooty mangabeys. Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support
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