Evidence-Based GI: An ACG Publication and Podcast
A new monthly publication from the American College of Gastroenterology, Evidence-Based GI (EBGI) uses evidence-based methods to create abstracts and explain study results of new and important articles in the field of gastroenterology and hepatology. Listen as editors of EBGI discuss the articles they review and how the recommendations can be applied to your practice.
Episodes
Acute Myeloid Leukemia and Myelodysplastic Syndrome with IBD and Thiopurines Impact on Risk
Screening Colonoscopy Decreases Colorectal Cancer Incidence and Related Mortality in Healthy Patients Over 75
Once-Weekly Semaglutide in Adults with Overweight or Obesity
Piecemeal Cold Snare Polypectomy of Large SSP: Cold Is the New Hot
Computer-aided Detection Systems increase detection of non-advanced adenomas, but is it ready for prime-time?
Inching Closer to a NASH Cure: Daily Semaglutide Achieves Resolution of NASH but Not Fibrosis after 72 Weeks
A New “Pill Prep” for Colonoscopy: An Effective Alternative for Individuals Who Won’t Drink GoLytely®
Treating All the Symptoms of IBS-C: Linaclotide Significantly Decreases Abdominal Pain, Bloating, and Discomfort
Hereditary Syndrome Risk Assessment in all Colorectal Cancer Patients: Keep it Simple!
Drainage for Infected Pancreatic Necrosis – Earlier Is Not Better
Slow Down to Speed Up Quality: Longer Withdrawal Time of 9 Versus 6 Minutes Increases Adenoma Detection Rate
Family Matters: Increased Risk of Colorectal Cancer among Individuals with Family History of Polyps
Effectiveness of Intermittent Fasting for Weight Loss: It’s Not Just When You Eat, but What You Eat, Too!
It’s a Bad “Prep” Even Though the Patient Took It Correctly: Consider 15 mg Bisacodyl plus 4-Liter PEG Split Prep Before Next Colonoscopy
Increased Risk of Metachronous Neoplasia After Incomplete Polyp Resection – Time to CARE About Polypectomy Technique!
Endoscopic Eradication Therapy for Neoplastic Barrett’s Esophagus Demonstrates 94% Treatment Success and Long-term Durability
Therapeutic Drug Monitoring of Maintenance Infliximab Is Beneficial for Patients with Immunemediated Inflammatory Diseases
Low Grade Dysplasia in Barrett’s Esophagus – Get Two Expert GI Pathologist Reviews and Repeat EGD After PPI Treatment
Tenapanor (IBSRELA) for Treatment of IBS-C: Effective over 26 Weeks
When Is Routine Prophylactic Clipping Indicated Post-Polypectomy?
SER-109, an Oral Microbiome Therapy, Decreases Recurrent Clostridiodes difficile Infection
ADR Isn’t the Only Game in Town: Proximal Serrated Lesion Detection Rates Predicts Interval Cancer Risk
Tiny Polyps-It’s OK to Remove Polyps equal or less than 3mm with Large Biopsy Forceps
Prophylactic Rifaximin Decreases Post-TIPS Hepatic Encephalopathy
ICYMI-Pantoprazole Prophylaxis Does Not Reduce 90-day Mortality and Clinically Significant Adverse Events in ICU Patients
Achieve IBD Remission Before Pregnancy: PIANO Registry Data Shows Adverse Perinatal Outcomes For Infants Associated with IBD Flares and Steroid Use; and Continue Thiopurines and Anti-TNF Agents If Your IBD Patient Becomes Pregnant
Time to Increase Adenoma Detection Rate Benchmarks for Screening Colonoscopies
Upadacitinib, a Selective JAK1 Inhibitor, for Moderate-Severe Ulcerative Colitis: Adjusting the Top-Down Treatment Algorithm for UC
Colonoscopy Reduces CRC Incidence and CRC-Related Mortality…. If You Get It!
High Adenoma Detection Rate Decreases Post-Colonoscopy CRC in FIT-Based Screening Program: Quality Matters!
Acute pancreatitis: Need IV fluid resuscitation but avoid a WATERFALL!
ICYMI: Surgery is Superior to Medical Therapy for PPI-Refractory Heartburn in the “Right” Patients
Vonoprazan, a Potassium-Channel Acid Blocker, is Superior to Lansoprazole for Managing Erosive Esophagitis
Reinvestigating the Lack of Association Between Proton Pump Inhibitor Use and Mortality by Accounting for Reverse Causation
RBX2660, a Donor Stool Product for Fecal Microbiota Transplant, Decreases Recurrent Clostridioides difficile Infection: The First FDA-Approved Live Biotherapeutic Product
NSAID Use and the Risk of IBD Exacerbations: Fact or Fiction
Continuing Anti-TNF Agents past 24 Weeks of Pregnancy Associated with Fewer IBD Relapses with No Increase in Adverse Fetal Outcomes
Ozanimod, a Selective Selective Sphingosine-1-Phosphatase Receptor Modulator, for Moderate-Severe Ulcerative Colitis: Re-Thinking the Top-Down Treatment Algorithm for UC
Risankizumab, an Interleukin-23 Inhibitor, for Moderate-Severe Crohn’s Disease: Advancing Care Beyond Anti-TNF Therapy
Risankizumab, an Interleukin-23 Inhibitor, for Moderate-Severe Crohn’s Disease: Advancing Care Beyond Anti-TNF Therapy
When It’s Not Acid Reflux: Managing PPI-Resistant GERD Patients Based on Bravo Results
ICYMI: Is Terlipressin for the Treatment of Hepato-Renal Syndrome Ready for Primetime: Results of the CONFIRM Trial
Dupilumab, an IgG4 Monoclonal Antibody, for Eosinophilic Esophagitis: Revising the Treatment Paradigm
Endoscopic Sleeve Gastroplasty Is Effective for Patients with Obesity Who MERIT Intervention
Early Colonoscopy for Acute Lower GI Bleeding Usually Is Not the Answer
Direct-Acting Antiviral Therapy for Hepatitis C Virus Decreases All-Cause Mortality and Decompensated Cirrhosis: Treat (Virtually) Everyone
Tumor-based screening for Lynch Syndrome: Check Every Colorectal Cancer
What are the Causes of Post-colonoscopy Colorectal Cancer?
10-Year Intervals After Normal Screening Colonoscopy: It’s Not Too Long with High-Quality Colonoscopy
Cold Snare Decreases Post-Polypectomy Bleeding vs Hot Snare for Small Polyps
SEAVUE: a Sea of Change in Biologic Positioning for Crohn’s Disease
ICYMI: Vedolizumab Is Superior to Adalimumab for Clinical Remission and Endoscopic Improvement of Ulcerative Colitis-The VARSITY RCT
Vibrating Capsules for Chronic Constipation: The New Non-Pharmacologic Approach
ICYMI: Can we prevent hepatic decompensation? Most likely, with nonselective beta blockers.
Disposable Elevator Caps for Duodenoscopes Decrease Persistent Bacterial Contamination Without Hindering Technical ERCP Performance: The ICECAP Trial
Over-the-Scope Clips Decrease Non-Variceal Upper GI Bleeding vs Standard Endoscopic Treatment… In the Right Patient
Prophylactic Antibiotics Do Not Improve Mortality in Severe Alcoholic Hepatitis Treated with Corticosteroids
Free Online Program Improves Adenoma Detection Rate and Decreases Post-Colonoscopy Colorectal Cancer
Screening Colonoscopy in the Elderly Population-Is Less Better?
Cephalosporins and Ciprofloxacin Still Appropriate First-Line Treatment for Spontaneous Bacterial Peritonitis
AGA-ACG Clinical Practice Guideline on Chronic Idiopathic Constipation Treatments: Parsing Benefits and Risks
Upadacitinib Is Effective for the Induction and Maintenance of Moderate-to-Severe Crohn’s Disease
Vedolizumab: An EARNEST Option for the Management of Chronic Pouchitis
Bariatric Surgery Is Superior to Lifestyle Changes + Best Medical Care for Metabolic Dysfunction-Associated Steatohepatitis: The BRAVES Study
Colonoscopy for Colon Polyp Surveillance: Avoid Recommending Early Surveillance
“Cooking Up Something New” with a One-Food Elimination Diet: A Simpler Approach to Dietary Therapy for Eosinophilic Esophagitis
Kiwifruit-A Specific Food To Improve Stool Frequency in Patients with Mild Constipation
ICYMI: Albumin Infusions Do Not Improve Outcomes in Hospitalized Patients with Decompensated Cirrhosis-The ATTIRE Trial
Surveillance Colonoscopy Recommendations in Older Adults With Limited Life Expectancy– More Work to be Done!
Time To Simplify ADR Calculation for Colonoscopy Quality Reporting
Cannabidiol: A Potential Therapeutic Option for Idiopathic and Diabetic Gastroparesis
American College of Physicians Guidance Statement on Colorectal Cancer Screening: Pitfalls of Second-Guessing Guidelines
Long Road to Achieving Competence in Cold Snare Polypectomy: Video-Based Feedback Can Help!
The New Frontier of Combination Therapy for IBD: The VEGA RCT
ICYMI: Biosimilar BI 695501 Has Similar Safety and Efficacy to Adalimumab for the Treatment of Crohn’s Disease: VOLTAIRE-CD Study
Hepatitis C Virus Testing and Treatment - A Call To Action
PPIs are NOT Associated with Dementia: Refuting Sensational Claims in a Post-Modern Epidemiologic Era
Etrasimod, a Sphingosine 1-Phosphate Receptor Modulator, for Moderate-Severe Ulcerative Colitis: New Options for Oral Therapy
Post-Endoscopy Esophageal Adenocarcinoma: Take a PEEC at Endoscopy Quality in Barrett's Esophagus
Surveillance of Branch Duct IPMN – Enough is Enough, At Least in Older Adults and Small, Stable Lesions
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