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The Business Brew

The Business Brew

Bill Brewster 200 Episodes May 7, 2026

The Business Brew is a podcast that explores the thought processes and analysis of investors and business professionals. Host Bill Brewster conducts long-form, in-depth discussions on finance, capital allocation, and the psychology of investing and business. The show features interviews with portfolio managers, analysts, and business operators. It is intended for informational and educational purposes only and does not constitute investment advice.

Episodes

Another FDA vs uniQure Episode May 7, 2026 01:20:52 Peter Mantas returns to the show. This is a follow up episode to the episode discussing uniQure. It's timely given the amount of media attention Marty Makary is getting; in part because of uniQure. Describing his trip on his Substack: "I flew to Washington D.C. on Friday (and drove to Baltimore on Saturday) with a thesis. I left with something harder to quantify, not a different thesis ex
Revisiting Fairfax Financial Apr 30, 2026 01:31:42 Charles Frischer and Asheef Lalani stop by The Business Brew to update the listeners on Fairfax Financial. They originally came on the program on 7/20/2023 when the stock was quite unloved. Bill asked them to return to the program after almost 3 years of ownership and fresh off the annual meeting. We hope the episode provides a good update to the first. Asheef Lalani as an independent director to
Evan Tindell Apr 24, 2026 01:37:56 Evan Tindell, CIO at Bireme Capital, returns to The Brew for a laid back conversation. The impetus for the conversation is Evan's Q4 letter. A year ago Evan came on the show to educate people about some mistakes he made in 2024. In that show he made the case for foreign stocks. The portfolio he discussed at that time did quite well (our words; not his) in 2025. Find out what he's thin
Sonu Chawla - Managing Mid Cap Exposure - $TSCM Mar 26, 2026 01:12:15 Sonu Chawla of Times Square Capital Management shares her investment philosophy, focusing on growth with a conscience, valuation discipline, and management assessment. Stocks discussed include Argenx, Carpenter Technologies, Cheniere, and JFrog. The conversation provides insights into how Sonu navigates market dislocations, valuation challenges, and sector opportunities.Sonu's bio: Sonu is a D
Notes From The Beauty Contest Mar 21, 2026 01:51:23 @crashkolnikov on X, and author of Notes From The Beauty Contest Substack, joins the show. Notes From The Beauty Contest is a long form Substack that focuses on stocks that are somewhat under covered elsewhere. It got its start with a deep dive into Regeneron, which is a primary focal point of this discussion. We hope you enjoy. Sponsorship InformationThank you to ⁠⁠⁠⁠⁠⁠⁠Trata⁠⁠⁠⁠⁠⁠⁠ for sponsori
Current Events - uniQure and the FDA Mar 6, 2026 01:35:14 uniQure is a business that develops gene therapies. uniQure's AMT-130 is currently in the headlines. This podcast episode attempts to present the Huntington's Disease community's arguments for why the FDA should work collaboratively to design a palatable drug trial. Last week the FDA told uniQure that AMT-130 would be subject to a double blind, Phase 3, randomized controlled study. Whi
Jacob Shapiro - A "Geopolitical Cousin" Joins the Show Mar 6, 2026 01:02:53 Jacob Shapiro is a geopolitical analyst who provides strategic guidance to families, investors, and corporations. He is a global thought leader in the area of geopolitics and its impact on everything from global markets to supply chains. You can find his Substack at https://substack.com/@jashap, his personal podcast at here (Apple) or here (Spotify), or you can follow Geopolitical Cousins here (Ap
Investing Unscripted Feb 13, 2026 01:26:22 Jeff and Jason, from the Investing Unscripted podcast, stop by the show for some general investment banter. Decent laughs, hopefully some smart thoughts, and a fun convo. Hope y'all enjoy!Sponsorship InformationThank you to ⁠⁠⁠⁠Trata⁠⁠⁠⁠ for sponsoring the show.If you're listening to this podcast, you'll like Trata. Trata is buyside to buyside conversations on individual stocks. Trata
Adam Wilk Feb 6, 2026 01:21:54 Adam Wilk, Founder and CIO of Greystone Capital Management discusses all things investing. Prior to launching Greystone, Adam worked in scouting and analytics roles with the San Antonio Spurs and Houston Rockets, followed by commercial credit underwriting at a major bank. Those roles emphasized disciplined decision-making under uncertainty and long time horizons, which are central to how Greystone
Paying It Forward Feb 1, 2026 00:24:35 Some Sunday thoughts and an offer from Bill.Sponsorship InformationThank you to ⁠⁠⁠Trata⁠⁠⁠ for sponsoring the show.If you're listening to this podcast, you'll like Trata. Trata is buyside to buyside conversations on individual stocks. Trata makes finding a bull or bear on any stock as easy as clicking two buttons. Over 125 funds globally contribute that collectively cover 2000+ tickers. Trata rai
Will Thomson - Real Returns: Real Assets Are Even Hotter Right Now Jan 29, 2026 01:29:47 Will Thomson returns! In this episode he has the audacity to suggest oil might be a smarter place to fish than gold. He also discusses copper as a theme. Bill likes Will. You should listen to Will. Will is a solid dude. Sponsorship InformationThank you to ⁠⁠Trata⁠⁠ for sponsoring the show.If you're listening to this podcast, you'll like Trata. Trata is buyside to buyside conversation
Quick Update Dec 26, 2025 00:10:44 Just some brief thoughts to communicate what's going on. While you are waiting for a new episode try Trata! trytrata.com/brewAnd remember to use Fiscal.ai for all your data needs. Fiscal.ai/brew

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