The Hunter Williams Podcast
The Hunter Williams Podcast explores health optimization through peptides, hormone therapy, metabolic health, and biohacking. Host Hunter Williams interviews researchers, doctors, and high-performers to provide insights beyond mainstream medicine. The show focuses on practical protocols for improving biological performance.
Episodes
The MOTS-c Masterclass | Complete Researcher’s Guide (2026)
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksIn this masterclass I break down what MOTS-c actually is. It's a tiny peptide your mitochondria make when you exercise. It's the only major peptide coded inside the mitochondrial genome, not the cell nucleus.I get into how it flips the AMPK switch, your cell's main fuel gauge. I cover the dual action that
The BPC-157 Masterclass | Complete Users Guide (2026)
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksBPC-157 is the peptide almost everyone starts with. In this masterclass I walk through why, and where the hype gets ahead of the evidence.We have about 30 years of animal studies on this one. We have fewer than 30 human subjects in published research. I keep that line clear the whole way through.I cover what BPC actua
Saturday Morning Coffee Talk 6/20/26
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/links
The KPV Masterclass | The Complete User's Guide
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksKPV is the most underrated peptide out there. Almost nobody talks about it. In my opinion it should be one of the most demanded peptides we have. If I had to choose, I'd take it over BPC and TB-500 every single time.Here's why. KPV is a tiny three amino acid fragment of alpha-MSH. It directly blocks NF-kappa B
The Tesamorelin Masterclass | The Complete User's Guide (2026)
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksTesamorelin is one of the few peptides I've seen actually move the needle on body composition. So I made a full masterclass on it.This is the user's guide as it stands in 2026. I cover what tesamorelin is, how it works, and the best practices I'd recommend for using it.We get into the growth hormone axis a
Saturday Morning Coffee Talk 6/6/26
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/links
The Complete TB-500 Masterclass: Dosing, Stacking, and More
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksTB-500 spends way too much time in BPC-157's shadow. I wanted to fix that.This is my full TB-500 masterclass. I go deep on what this peptide actually does, and why it works so differently than BPC even though we lump them together as the Wolverine stack.First I clear up the confusion between TB-500 and thymosin be
Reader Mailbag 4 — Peptide Overdoses, GLP-1 Anhedonia & Hormone Truths
Taylor and I are back for another Reader Mailbag. This one covers a lot of ground.We start with anhedonia on GLP-1s because the questions on this have been nonstop. People are experiencing it on Semaglutide, Tirzepatide, and Retatrutide and we break down why it happens, whether it is dose related, and what you can actually do about it.From there we get into the Reta and heart rate debate, Taylor&#
The May 2026 Q&A | Retatrutide, Testosterone, Autoimmune, and Beyond
Hey everybody, this is the May 2026 Q&A video, and we made it through a packed hour of your questions. I had so many submitted that I had to print them off and group them by category to get through them all.All My Links Here: https://hunterwilliamshealth.com/linksWe cover a lot of ground. GLPs and fertility, hunger on retatrutide, dopamine differences between Sema, Tirz, and Retta, GLP side
The SS-31 Masterclass | Dosing, Stacking, Cycling, and Why It's A Top 3 Peptide
All links here: https://hunterwilliamshealth.com/linksSS-31 continues to be one of my favorite peptides of all time, and the more data that comes out on it, the more I think every person over 25 has a use case for it.In this masterclass, I'm breaking down everything I know about SS-31. We cover what it actually does at the cellular level, why it's the first FDA-approved mitochondrial pept
Peptides and Cancer | 20+ Studies the Critics Won't Show You
All links here: https://hunterwilliamshealth.com/linksTimestamps:00:00 Intro01:00 Why I'm making this video04:00 The plan: peptides with direct anti-cancer evidence06:02 AOD-9604 and HGH Frag 176-19107:42 BPC-15709:54 DSIP (Delta Sleep Inducing Peptide)11:08 Epitalon12:30 Follistatin 34413:30 GHK-Cu14:36 Kisspeptin15:58 KPV17:18 LL-3718:46 Melanotan 219:58 MOTS-c21:12 Retatrutide22:34 Semaglu
Retatrutide Masterclass | Dosing, Side Effects, and the Framework Most People Get Wrong
All links here: https://hunterwilliamshealth.com/links00:00 — Intro and why I'm doing these masterclasses02:42 — What we're covering and the regulatory timeline04:04 — The two users: weight loss vs longevity05:30 — What Retatrutide actually does (the three receptors)06:50 — Why the glucagon receptor makes Retatrutide different07:54 — Weight loss trial data (1mg to 12mg)10:50 — The longevit
Saturday Morning Coffee Talk 5/16/26
All Links Here: https://hunterwilliamshealth.com/links
Episode 4 — Why the 49ers Can't Stay Healthy | Peter Cowan on EMF, Substations, and Your Hormones
If you do everything right and still feel off, this episode is for you.I sat down with Peter Cowan, a quantum biology practitioner and environmental health investigator who got chronically sick from EMF exposure, walked away from Silicon Valley, and spent years figuring out why on his own. Peter's Substack series on the San Francisco 49ers, who practice and play right next to a power substatio
This Peptide Works 10X Faster Than SSRIs (Here's How)
👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/linksPE-22-28 is one of those peptides almost nobody is talking about, and I think that's a shame. In this episode I walk you through what it is, how it works, and why I'd put it in the antidepressant category before I'd call it a true nootropic.I get into the background as an optimized analogue of spadin, the TREK-1 channel i
Reader Mailbag 3 — Traveling, Glutathione, Sleep & More | Hunter & Taylor Williams
Hunter and Taylor are back for another deep dive Reader Mailbag. Real questions, real answers, no shortcuts.This week: traveling with peptides and TRT through customs, fixing glutathione injection pain, melanatan 1 vs 2 and skin cancer risk, severe female insomnia and perimenopause sleep protocols, retatrutide plateaus and GLP-1 desensitization, and how to actually build a peptide stack using the
20 Fat Loss Compounds Ranked Worst to Best (No GLP-1s)
👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/linksGLP-1s like retatrutide are the kings of fat loss. No argument there. But what do you actually do when you're cycling off, when GLP-1s aren't on the table, or when you want to stack something alongside your GLP-1 so you don't have to escalate the dose?In this video I rank 20 non-GLP-1 fat loss compounds from F-tier to S-t
Saturday Morning Coffee Talk 5/2/26
All links here: https://hunterwilliamshealth.com/links
LDN | The Force Multiplier for Peptides and HRT
👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/linksLow-dose naltrexone is one of my favorite compounds out there, and in this updated 2026 episode I'm breaking down why it deserves a spot in your protocol. I cover the four mechanisms that make LDN work: the endorphin rebound, the OGF/OGFR axis, TLR4 antagonism, and broad anti-inflammatory signaling. Then I get into where LDN actu
April 2026 Solo Q&A — Every Question Answered | Hunter Williams
Every question that came in over the last month. No filters, no shortcuts. This is the April 2026 edition of the solo Q&A and Hunter covers everything from women's hormone optimization and PCOS to vasectomy impacts on men's health, peptides for neurological conditions, bioregulator cycling protocols, and everything in between.For research and entertainment purposes only.0:00 — Intro &a
Reader Mailbag 2 — Autoimmune, Fertility, Cancer & More | Hunter & Taylor Williams
Hunter and Taylor are back for another Reader Mailbag — six questions, real answers, no shortcuts.This week: building a peptide protocol for autoimmune disease in women, Hunter and Taylor's personal fertility journey on TRT, how to think about peptides and cancer risk, optimizing health for seniors stuck on statins, muscle preservation for perimenopausal women on GLPs, and everything you need to k
Is C02 Therapy The Ultimate Biohack?
In today's episode, we're taking a detour from our usual peptide discussions to dive into one of my absolute favorite biohacking devices: the carbon dioxide therapy inhaler from CarboGenetics. I know what you're thinking—why would we want to inhale CO2 when we usually focus on getting more oxygen? It all comes down to a fascinating physiological mechanism called the Bohr effect. I'll break down th
Saturday Morning Coffee Talk 4/18/26
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The FDA Just Changed Everything for Peptides | My Honest Take
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Hunter & Taylor Answer Your Most Pressing Health Questions | Reader Mailbag Episode 1
Hunter and Taylor Williams sit down for their first ever Reader Mailbag episode — a brand new deep dive Q&A format where they take the questions that need more than 60 seconds and actually break them down together.Most Q&As are rapid fire. This one isn't. Hunter and Taylor go deep on some of the most common but most underanswered questions they receive — covering women's hormones,
The 5 Most Overrated Peptides (And What I'd Use Instead)
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March 2026 Q&A | GLP-1s, GH Peptides, Healing, Autoimmune & More | Hunter Williams
Hunter Williams answers your March 2026 submitted questions across six categories — GLP-1s, growth hormone secretagogues, healing & injury recovery, metabolic peptides, men's health, and autoimmune support.Topics covered in this episode:Tirzepatide at max dose (15mg) — what to do when you've plateaued and how to transition to retatrutide safelyRetatrutide side effects — nausea, gut shu
Survodutide & Mazdutide | The GLP-1/Glucagon Duo That Could Rival Reta
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Saturday Morning Coffee Talk 3/28/26
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Peptides & Longevity Medicine Explained by a Real Cardiologist | Dr. Abid Husain, MD
Dr. Abid Husain is a triple board-certified cardiologist in cardiology, internal medicine, and functional medicine. After years in the traditional hospital system in New Jersey, he walked away to focus on what actually prevents disease — and now practices at the Boulder Longevity Institute, combining conventional medicine with peptides, HRT, and longevity protocols.This is one of the most importan
Dihexa Deep Dive | Dosing, Safety, and Why I Keep Coming Back to It
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The Next Big Things in Biohacking | EMF, Peptides, and Superhuman Performance with Alex Kikel
Hunter and Taylor sit down in person with Alex Kikel — biohacker, performance coach, and one of the most forward-thinking minds in the peptide and longevity space — for one of the most information-dense conversations the podcast has ever had.In this episode, they go deep on the science of coherent vs. non-coherent EMF and why it matters more than most people realize, structured water and how your
Spermidine for Longevity
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Saturday Morning Coffee Talk 3/14/26
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Peptide Secrets Revealed: BPC-157, TB-500, GLP Microdosing & Hormones with Sarah Morgan
Peptide foundations, GLP micro-dosing, hormone optimization, and the peptides most people are using wrong — Hunter Williams and Taylor sit down with Sarah Morgan, nutritional biochemist and founder of Amino Academy, for one of the most educational peptide conversations on the internet.Sarah comes from a family of cardiologists, holds a Master's in Nutrition from the University of Bridgeport, and h
Hematocrit on TRT Explained
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DADA Deep Dive | My Updated Take on an Underrated Performance Enhancer
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Saturday Morning Coffee Talk 2/28/26
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Peptides & Mast Cell Activation | What You Need to Know + How To Fix It
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February 2026 Q&A | GLPs for Pain, Mast Cell Fixes, Microdosing Reta & More!
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FOXO4-DRI | The Senolytic “Tune-Up” Peptide for Healthy Aging
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Pinealon | The Underrated Peptide for Sleep, Stress, and Longevity
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Saturday Morning Coffee Talk | 2/7/26
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Best Fertility Add-Ons for TRT
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The Quest for Clean Energy | Caffeine vs TeaCrine vs Paraxanthine
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January 2026 Q&A | VIP, Reta, GLP-1s, Gut Healing, TRT, Brain Support
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P21 | The Brain Peptide Nobody Is Talking About
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Beyond ED | Viagra For Longevity
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Cardarine for Longevity and Performance | Revisiting GW-501516 in 2026
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Saturday Morning Coffee Talk 1/17/26
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GLOW and KLOW are Worthless?! | A Deep Dive Analysis on Peptide Stability
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VIP | Is It The Most Versatile Peptide Ever?
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Vesilute | The Bladder Peptide
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GLP-1s and Anhedonia | Do GLPs Cause Emotional Blunting?
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Saturday Morning Coffee Talk | 1/3/26
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IGF-1 LR3 for Longevity | How I Like to Use It
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Thymogen Explained | The Immune Reset Peptide You’re Not Using
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Intramuscular vs Subcutaneous Testosterone Explained
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Peptides, Prevention, and the Future of Longevity | My Fountain Life Experience
CORRECTION: SS-31 is a synthetic peptide, not an endogenous peptide. MOTS-c is an endougenous peptide. Join My Private Group: https://theaxioncollective.manus.space/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidec
December 2025 Q&A | Answering All Your Questions!
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Humanin | The Mitochondrial Peptide for Brain Health and Longevity
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The Best Biohacking Device In My House | The Bimini NanoJet Deep Dive
If you decide to pick one up, you can get $500 off your purchase by using the code HUNTERW at checkout on the Bimini site. You can check out the different models here. I have the Nanojet Eco (Eco for home, Pro/All-In for facilities).👉 Bimini products page: https://biminihydrotherapy.com/products/ Join My Private Group: https://theaxioncollective.manus.space/Email List: https://hu
Beyond Sleep | How DSIP Resets Stress, Pain, and Circadian Rhythm
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The Peptide Stack For Lung Health
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The Peptide Stack That Reverses Liver Fat
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Do GLP-1s Prevent Cancer?
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Estrogen Is Not the Enemy | The Truth About TRT and AIs
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The Kidney Health Peptide Blueprint
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The Injectable L-Carnitine Deep Dive
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Saturday Morning Coffee With Taylor and Hunter
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Testosterone's Role in Mental Health
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GHRHs vs GHRPs | How to Use and Stack Them
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SGLT2 Inhibitors and GLP-1s | The Holy Grail of Longevity Medicine
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How Thymosin Alpha 1 Supercharges Your Immune System
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Peptide Replacement Therapy | The Future of Anti-Aging Medicine
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Pregnenolone Explained | When It Helps and When It Doesn’t
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Microdosing Retatrutide vs Weekly Shots
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