The Hunter Williams Podcast
The Hunter Williams Podcast explores health optimization through peptides, hormone therapy, metabolic health, and biohacking. Host Hunter Williams interviews researchers, doctors, and high-performers to provide insights beyond mainstream medicine. The show focuses on practical protocols for improving biological performance.
Episodes
Ep. 10 | From Federal Prison to Functional Health With Samantha Lander
Samantha Lander is one of the most compelling voices in functional health and peptide coaching, and her path to getting here is unlike anyone else in the space. She’s a functional diagnostic nutritionist who went from addiction, federal prison, and a money laundering charge to building one of the most effective coaching practices for people who’ve tried everything and still can’t get results.She w
IGF-1 Masterclass | A Complete Research Guide (2026)
Most people treat IGF-1 LR3 like a muscle peptide you just add to the cart. I want to slow that down a bit.In this masterclass I break down IGF-1 LR3 and IGF-1 DES. Both are modified versions of the IGF-1 your liver makes. They work by dodging the binding proteins that keep most of your IGF-1 parked and inactive. More free IGF-1 means more signal actually reaching the muscle.I cover who these make
Ep. 9 | Dr. Tyna Moore on GLP-1 Micro Dosing, HRT, Joint Healing, and Why She Got Censored
Dr. Tyna Moore is one of the most censored voices in the peptide and HRT space. She’s a naturopathic doctor with decades of clinical experience in regenerative medicine and was one of the first practitioners advocating for intelligent, individualized use of GLP-1s before it was mainstream. Instagram silenced her in 2024 right as the conversation was heating up. Today she’s here to set the record s
The P21 Masterclass | A Complete Research Guide (2026)
P21 is one of my favorite brain peptides. It's also one of the least talked about.In this masterclass I break down everything I know about it. That includes the mechanism, the research, and how I actually use it.Here's the honest part up front. There is zero published human data on P21. Everything we have comes from cell and animal studies. The dosing I share is built from my own experienc
Saturday Morning Coffee Talk 10/3/26
All links here: https://hunterwilliamshealth.com/links
The Glutathione Masterclass | A Complete Research Guide (2026)
Glutathione is the most boring compound I use. It's also one I'd put in my top five peptides.Your cells make it every day. It's your main internal antioxidant, the buffer that soaks up the damaging byproducts of making energy. Levels drop with age, alcohol, illness and hard training. When that tank runs low, a lot of other therapies stop working as well.In this masterclass I break down
The ARA-290 Masterclass | A Complete Research Guide (2026)
Most peptides get knocked for having no human trials. ARA-290 is one of the few that does. Randomized, placebo-controlled studies show it regrowing small nerve fibers.In this masterclass I walk through where it came from. It was built out of EPO, the kidney hormone made famous by blood doping. The researchers kept the tissue repair side and left out the red blood cell side. So no rise in hematocri
The Cartalax Masterclass | A Research Guide (2026)
Most people have never heard of Cartalax. I think it's the peptide that gets healing done when BPC-157 and TB-500 stall out.This is the full masterclass. Cartalax is a three amino acid bioregulator from the Khavinson group in Russia. BPC and TB-500 work on growth factors at the cell surface. Cartalax goes inside the nucleus and changes which genes cartilage cells express. In cell culture it ro
The LL-37 Masterclass | A Research Guide (2026)
LL-37 is the peptide I think everyone should have on hand and almost nobody should be taking every day.It's the only cathelicidin in the human body. That's an antimicrobial peptide your immune system makes to punch holes in bacteria, break up biofilms, and neutralize endotoxins. In this masterclass I walk through how it works. I cover why your vitamin D level decides whether your body can
Saturday Morning Coffee Talk 9/5/26
All links here: https://hunterwilliamshealth.com/links
Ep. 8 | The Missing Layer | Yvonne Cropp on Color Puncture, Trauma, and Sovereignty
We cover what color puncture actually is and the science behind it, how it works on the prefrontal cortex, why emotional trauma has the same cellular imprint as physical injury, what sovereignty actually means and why most people have given theirs away, how color helped Taylor heal plantar fasciitis that peptides and hormones could not touch, the GLP and anhedonia story that stopped me in my track
The NAD+ Masterclass | A Research Guide (2026)
NAD+ is not a peptide. That one fact changes how you should use it.Peptides send a signal. NAD+ is a coenzyme, meaning it does the work itself. There is no receptor to downregulate, so the cycling logic is completely different.In this one I walk through what NAD+ actually does inside the cell, what burns through it, and whether it really crashes with age. The decline is real. It is just far more m
Ep. 7 | TRT, Fertility, and Hair Growth | Han Sijmons of Arcanum Health
Han Sijmons flew in from Holland to sit down with Taylor and me and we just let it rip. Hans is a nurse, an EMT, and one of the most genuinely knowledgeable people I have met in this space. He came up through the same world as Alex Kikel and has been quietly coaching and optimizing people in Europe for years.We covered a lot of ground. His journey starting TRT in Holland as a younger guy and fight
MGF and PEG-MGF Masterclass | A Research Guide (2026)
If you already ran BPC-157 and TB-500 and still have a nagging injury, this one is for you.MGF stands for mechano growth factor. It is a 24 amino acid fragment of IGF-1. That is the growth factor your body makes in response to training and damage. It came out of the bodybuilding world as a site injection peptide. That never panned out.What it actually does is more interesting to me. It does not ra
Saturday Morning Coffee Talk 8/22/26
All Links Here: https://hunterwilliamshealth.com/links
Ep. 6 | Perimenopausal Women, GLPs, and the Peptide Wild West | Stephanie Gambetta of Loop Health
Stephanie Gambetta flew out to North Carolina and sat down with Taylor and me for what ended up being one of the most honest conversations I have had about the peptide space.Stephanie runs Loop Health and has probably worked with more perimenopausal and menopausal women on peptides and GLPs than anyone in the country. She has the boots on the ground data that most people in this space do not have
The Epitalon Masterclass | A Research Guide (2026)
All Links Here: https://hunterwilliamshealth.com/linksEpitalon might be the most requested masterclass I have done. It might also be the most misunderstood peptide out there.Most people run 5 to 10 milligrams a day because that number is everywhere online. I dig into where it actually came from, and it is not where you think. Those doses were built around epithalamin, the crude pineal extract
Melanotan 1 and 2 Masterclass | A Research Guide (2026)
All Links Here: https://hunterwilliamshealth.com/linksMelanotan 1 and Melanotan 2 are the two peptides people ask me about every summer. So I put together the full masterclass on both.I combined them because you cannot really talk about one without the other. They came out of the same research program at the University of Arizona. But they hit different receptors, and that changes everything ab
Saturday Morning Coffee Talk 8/8/26
All links here: https://hunterwilliamshealth.com/links
CJC-1295 Masterclass | A Complete Research Guide (2026)
CJC-1295 is one of the most purchased peptides in the research space. It is also one of the least understood.Most people pick it up because a friend told them to. Then they run into side effects nobody warned them about. Around 70% get injection site reactions. Plenty get flushing, hives, or headaches. That does not make it a bad peptide. It just means you should know what you are walking into.In
Ep. 5 | The Missing Layer | Brandon Amalani on EMF and Electrotherapy
Most people I talk to are doing everything right with peptides and hormones and still have a layer they have never touched.I brought Brandon Amalani on for exactly that reason. He has spent over 20 years at the intersection of traditional Chinese medicine, Japanese herbal systems, EMF research, and electrotherapy. He built his own PEMF device from scratch because nothing on the market met his stan
DSIP Masterclass | A Researcher’s Guide to the Sleep Peptide (2026)
All Links Here: https://hunterwilliamshealth.com/linksMost people take DSIP expecting a peptide version of Ambien. That's why they end up writing it off.DSIP won't knock you out. It won't help you fall asleep either. What it does is normalize the structure of your sleep once it starts. It also turns down the volume on your stress axis.In this masterclass I walk through all of it. What
Saturday Morning Coffee Talk 7/25/26
All Links Here: https://hunterwilliamshealth.com/links
The GHK-cu Masterclass | A Complete Researcher’s Guide (2026)
All Links Here: https://hunterwilliamshealth.com/linksMost people file GHK-Cu under skin and beauty. That sells it short.This little three amino acid peptide shifts around 4,000 human genes toward repair. It delivers copper to the enzymes that rebuild collagen and power your cells. Your body makes it, and you lose about 80% of it by age 60.In this masterclass I cover what it actually does and how
The Ipamorelin Masterclass | A Complete Research Guide (2026)
All Links Here: https://hunterwilliamshealth.com/linksIpamorelin might be the best peptide to start with if you have never touched growth hormone.In this masterclass I break down why. It pushes out your own growth hormone without dragging cortisol, prolactin, or hunger along with it. That clean profile is the whole reason it is still around.I go through what it actually does in the body. It starts
The Thymosin Alpha-1 Masterclass | Complete Researcher's Guide (2026)
All links here:https://hunterwilliamshealth.com/linksIn this masterclass I break down TA-1 from the ground up. It works like a thermostat for your immune system. It turns a weak response up and pulls an overactive one back toward the middle.One thing up front. You will not feel this peptide when you inject it. That is normal. It works slowly over weeks.I cover who this peptide is really for. Older
The MOTS-c Masterclass | Complete Researcher’s Guide (2026)
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksIn this masterclass I break down what MOTS-c actually is. It's a tiny peptide your mitochondria make when you exercise. It's the only major peptide coded inside the mitochondrial genome, not the cell nucleus.I get into how it flips the AMPK switch, your cell's main fuel gauge. I cover the dual action that
The BPC-157 Masterclass | Complete Users Guide (2026)
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksBPC-157 is the peptide almost everyone starts with. In this masterclass I walk through why, and where the hype gets ahead of the evidence.We have about 30 years of animal studies on this one. We have fewer than 30 human subjects in published research. I keep that line clear the whole way through.I cover what BPC actua
Saturday Morning Coffee Talk 6/20/26
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/links
The KPV Masterclass | The Complete User's Guide
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksKPV is the most underrated peptide out there. Almost nobody talks about it. In my opinion it should be one of the most demanded peptides we have. If I had to choose, I'd take it over BPC and TB-500 every single time.Here's why. KPV is a tiny three amino acid fragment of alpha-MSH. It directly blocks NF-kappa B
The Tesamorelin Masterclass | The Complete User's Guide (2026)
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksTesamorelin is one of the few peptides I've seen actually move the needle on body composition. So I made a full masterclass on it.This is the user's guide as it stands in 2026. I cover what tesamorelin is, how it works, and the best practices I'd recommend for using it.We get into the growth hormone axis a
Saturday Morning Coffee Talk 6/6/26
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/links
The Complete TB-500 Masterclass: Dosing, Stacking, and More
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksTB-500 spends way too much time in BPC-157's shadow. I wanted to fix that.This is my full TB-500 masterclass. I go deep on what this peptide actually does, and why it works so differently than BPC even though we lump them together as the Wolverine stack.First I clear up the confusion between TB-500 and thymosin be
Reader Mailbag 4 — Peptide Overdoses, GLP-1 Anhedonia & Hormone Truths
Taylor and I are back for another Reader Mailbag. This one covers a lot of ground.We start with anhedonia on GLP-1s because the questions on this have been nonstop. People are experiencing it on Semaglutide, Tirzepatide, and Retatrutide and we break down why it happens, whether it is dose related, and what you can actually do about it.From there we get into the Reta and heart rate debate, Taylor&#
The May 2026 Q&A | Retatrutide, Testosterone, Autoimmune, and Beyond
Hey everybody, this is the May 2026 Q&A video, and we made it through a packed hour of your questions. I had so many submitted that I had to print them off and group them by category to get through them all.All My Links Here: https://hunterwilliamshealth.com/linksWe cover a lot of ground. GLPs and fertility, hunger on retatrutide, dopamine differences between Sema, Tirz, and Retta, GLP side
The SS-31 Masterclass | Dosing, Stacking, Cycling, and Why It's A Top 3 Peptide
All links here: https://hunterwilliamshealth.com/linksSS-31 continues to be one of my favorite peptides of all time, and the more data that comes out on it, the more I think every person over 25 has a use case for it.In this masterclass, I'm breaking down everything I know about SS-31. We cover what it actually does at the cellular level, why it's the first FDA-approved mitochondrial pept
Peptides and Cancer | 20+ Studies the Critics Won't Show You
All links here: https://hunterwilliamshealth.com/linksTimestamps:00:00 Intro01:00 Why I'm making this video04:00 The plan: peptides with direct anti-cancer evidence06:02 AOD-9604 and HGH Frag 176-19107:42 BPC-15709:54 DSIP (Delta Sleep Inducing Peptide)11:08 Epitalon12:30 Follistatin 34413:30 GHK-Cu14:36 Kisspeptin15:58 KPV17:18 LL-3718:46 Melanotan 219:58 MOTS-c21:12 Retatrutide22:34 Semaglu
Retatrutide Masterclass | Dosing, Side Effects, and the Framework Most People Get Wrong
All links here: https://hunterwilliamshealth.com/links00:00 — Intro and why I'm doing these masterclasses02:42 — What we're covering and the regulatory timeline04:04 — The two users: weight loss vs longevity05:30 — What Retatrutide actually does (the three receptors)06:50 — Why the glucagon receptor makes Retatrutide different07:54 — Weight loss trial data (1mg to 12mg)10:50 — The longevit
Saturday Morning Coffee Talk 5/16/26
All Links Here: https://hunterwilliamshealth.com/links
Episode 4 — Why the 49ers Can't Stay Healthy | Peter Cowan on EMF, Substations, and Your Hormones
If you do everything right and still feel off, this episode is for you.I sat down with Peter Cowan, a quantum biology practitioner and environmental health investigator who got chronically sick from EMF exposure, walked away from Silicon Valley, and spent years figuring out why on his own. Peter's Substack series on the San Francisco 49ers, who practice and play right next to a power substatio
This Peptide Works 10X Faster Than SSRIs (Here's How)
👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/linksPE-22-28 is one of those peptides almost nobody is talking about, and I think that's a shame. In this episode I walk you through what it is, how it works, and why I'd put it in the antidepressant category before I'd call it a true nootropic.I get into the background as an optimized analogue of spadin, the TREK-1 channel i
Reader Mailbag 3 — Traveling, Glutathione, Sleep & More | Hunter & Taylor Williams
Hunter and Taylor are back for another deep dive Reader Mailbag. Real questions, real answers, no shortcuts.This week: traveling with peptides and TRT through customs, fixing glutathione injection pain, melanatan 1 vs 2 and skin cancer risk, severe female insomnia and perimenopause sleep protocols, retatrutide plateaus and GLP-1 desensitization, and how to actually build a peptide stack using the
20 Fat Loss Compounds Ranked Worst to Best (No GLP-1s)
👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/linksGLP-1s like retatrutide are the kings of fat loss. No argument there. But what do you actually do when you're cycling off, when GLP-1s aren't on the table, or when you want to stack something alongside your GLP-1 so you don't have to escalate the dose?In this video I rank 20 non-GLP-1 fat loss compounds from F-tier to S-t
Saturday Morning Coffee Talk 5/2/26
All links here: https://hunterwilliamshealth.com/links
LDN | The Force Multiplier for Peptides and HRT
👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/linksLow-dose naltrexone is one of my favorite compounds out there, and in this updated 2026 episode I'm breaking down why it deserves a spot in your protocol. I cover the four mechanisms that make LDN work: the endorphin rebound, the OGF/OGFR axis, TLR4 antagonism, and broad anti-inflammatory signaling. Then I get into where LDN actu
April 2026 Solo Q&A — Every Question Answered | Hunter Williams
Every question that came in over the last month. No filters, no shortcuts. This is the April 2026 edition of the solo Q&A and Hunter covers everything from women's hormone optimization and PCOS to vasectomy impacts on men's health, peptides for neurological conditions, bioregulator cycling protocols, and everything in between.For research and entertainment purposes only.0:00 — Intro &a
Reader Mailbag 2 — Autoimmune, Fertility, Cancer & More | Hunter & Taylor Williams
Hunter and Taylor are back for another Reader Mailbag — six questions, real answers, no shortcuts.This week: building a peptide protocol for autoimmune disease in women, Hunter and Taylor's personal fertility journey on TRT, how to think about peptides and cancer risk, optimizing health for seniors stuck on statins, muscle preservation for perimenopausal women on GLPs, and everything you need to k
Is C02 Therapy The Ultimate Biohack?
In today's episode, we're taking a detour from our usual peptide discussions to dive into one of my absolute favorite biohacking devices: the carbon dioxide therapy inhaler from CarboGenetics. I know what you're thinking—why would we want to inhale CO2 when we usually focus on getting more oxygen? It all comes down to a fascinating physiological mechanism called the Bohr effect. I'll break down th
Saturday Morning Coffee Talk 4/18/26
Website: https://hunterwilliamshealth.com/Get my FREE Cheatsheet: https://hunterwilliamshealth.com/peptidecheatsheetJoin My Private Group: https://theaxioncollective.manus.space/Get My Book On Amazon: https://a.co/d/avbaV48DownloadSupplement Sources: https:/
The FDA Just Changed Everything for Peptides | My Honest Take
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Hunter & Taylor Answer Your Most Pressing Health Questions | Reader Mailbag Episode 1
Hunter and Taylor Williams sit down for their first ever Reader Mailbag episode — a brand new deep dive Q&A format where they take the questions that need more than 60 seconds and actually break them down together.Most Q&As are rapid fire. This one isn't. Hunter and Taylor go deep on some of the most common but most underanswered questions they receive — covering women's hormones,
The 5 Most Overrated Peptides (And What I'd Use Instead)
Website: https://hunterwilliamshealth.com/Get my FREE Cheatsheet: https://hunterwilliamshealth.com/peptidecheatsheetJoin My Private Group: https://theaxioncollective.manus.space/Get My Book On Amazon: https://a.co/d/avbaV48DownloadSupplement Sources: https://hunterwi
March 2026 Q&A | GLP-1s, GH Peptides, Healing, Autoimmune & More | Hunter Williams
Hunter Williams answers your March 2026 submitted questions across six categories — GLP-1s, growth hormone secretagogues, healing & injury recovery, metabolic peptides, men's health, and autoimmune support.Topics covered in this episode:Tirzepatide at max dose (15mg) — what to do when you've plateaued and how to transition to retatrutide safelyRetatrutide side effects — nausea, gut shu
Survodutide & Mazdutide | The GLP-1/Glucagon Duo That Could Rival Reta
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Saturday Morning Coffee Talk 3/28/26
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Peptides & Longevity Medicine Explained by a Real Cardiologist | Dr. Abid Husain, MD
Dr. Abid Husain is a triple board-certified cardiologist in cardiology, internal medicine, and functional medicine. After years in the traditional hospital system in New Jersey, he walked away to focus on what actually prevents disease — and now practices at the Boulder Longevity Institute, combining conventional medicine with peptides, HRT, and longevity protocols.This is one of the most importan
Dihexa Deep Dive | Dosing, Safety, and Why I Keep Coming Back to It
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The Next Big Things in Biohacking | EMF, Peptides, and Superhuman Performance with Alex Kikel
Hunter and Taylor sit down in person with Alex Kikel — biohacker, performance coach, and one of the most forward-thinking minds in the peptide and longevity space — for one of the most information-dense conversations the podcast has ever had.In this episode, they go deep on the science of coherent vs. non-coherent EMF and why it matters more than most people realize, structured water and how your
Spermidine for Longevity
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Saturday Morning Coffee Talk 3/14/26
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Peptide Secrets Revealed: BPC-157, TB-500, GLP Microdosing & Hormones with Sarah Morgan
Peptide foundations, GLP micro-dosing, hormone optimization, and the peptides most people are using wrong — Hunter Williams and Taylor sit down with Sarah Morgan, nutritional biochemist and founder of Amino Academy, for one of the most educational peptide conversations on the internet.Sarah comes from a family of cardiologists, holds a Master's in Nutrition from the University of Bridgeport, and h
Hematocrit on TRT Explained
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DADA Deep Dive | My Updated Take on an Underrated Performance Enhancer
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Saturday Morning Coffee Talk 2/28/26
Join My Private Group: https://theaxioncollective.manus.space/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.ca
Peptides & Mast Cell Activation | What You Need to Know + How To Fix It
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February 2026 Q&A | GLPs for Pain, Mast Cell Fixes, Microdosing Reta & More!
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FOXO4-DRI | The Senolytic “Tune-Up” Peptide for Healthy Aging
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Pinealon | The Underrated Peptide for Sleep, Stress, and Longevity
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Saturday Morning Coffee Talk | 2/7/26
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Best Fertility Add-Ons for TRT
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The Quest for Clean Energy | Caffeine vs TeaCrine vs Paraxanthine
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January 2026 Q&A | VIP, Reta, GLP-1s, Gut Healing, TRT, Brain Support
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P21 | The Brain Peptide Nobody Is Talking About
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Beyond ED | Viagra For Longevity
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Cardarine for Longevity and Performance | Revisiting GW-501516 in 2026
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Saturday Morning Coffee Talk 1/17/26
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GLOW and KLOW are Worthless?! | A Deep Dive Analysis on Peptide Stability
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VIP | Is It The Most Versatile Peptide Ever?
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Vesilute | The Bladder Peptide
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GLP-1s and Anhedonia | Do GLPs Cause Emotional Blunting?
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