Physionic

Glycine Restriction for Cancer, Berberine against Colorectal Cancer, and More Apr 20, 2026 03:40:02 *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]*Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy*JOIN THE COMMUNITY*Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2*EMAIL LIST*1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6*HIRE ME FOR CONSULTING:*

Collagen for Skin 'Debunked, Non-Nutritive Sweeteners on Cognitive Decline, Seed Oils, and More Oct 25, 2025 03:05:49 *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]*Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy*JOIN THE COMMUNITY*Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2*EMAIL LIST*1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6*HIRE ME FOR CONSULTING:*

Age Reversing Antibodies, Glycine and Longevity, Ergothioneine and Mitochondria, and More Sep 21, 2024 03:31:01 *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders [Standard Tier]: https://bit.ly/PhysionicInsiders2 Join the Physionic Insiders [Pro Tier]: https://bit.ly/PhysionicInsidersPro *Standard Tier:* Access to the Premium Video Library, Full Study Analyses (+ Summaries), Insider Podcast, , Research Reviews, and More *Pro Tier:* All benefits of the Standard Tier + Live

Reversing Heart Disease, Creatine on Kidney Health, 5 Life Extending Habits, and More May 4, 2024 05:03:56 *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders [Standard Tier]: https://bit.ly/PhysionicInsiders2 Join the Physionic Insiders [Pro Tier]: https://bit.ly/PhysionicInsidersPro *Standard Tier:* Access to the Premium Video Library, Full Study Analyses (+ Summaries), Insider Podcast, , Research Reviews, and More *Pro Tier:* All benefits of the Standard Tier + Live

Oreos lowering Blood Cholesterol, Science Communication, Mechanisms of Heart Disease, Ft. Dr. Norwitz, Dave Feldman Mar 16, 2024 03:16:01 *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders [Standard Tier]: https://bit.ly/PhysionicInsiders2 Join the Physionic Insiders [Pro Tier]: https://bit.ly/PhysionicInsidersPro *Standard Tier:* Access to the Premium Video Library, Full Study Analyses (+ Summaries), Insider Podcast, , Research Reviews, and More *Pro Tier:* All benefits of the Standard Tier + Liv

Dr. Brad Stanfield: A Discussion of Supplements for Longevity and Health Dec 18, 2023 00:53:37 *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT] *Join the Physionic Insiders [Standard Tier]: https://bit.ly/PhysionicInsiders2 Join the Physionic Insiders [Pro Tier]: https://bit.ly/PhysionicInsidersPro *Standard Tier:* Access to the Premium Video Library, Full Study Analyses (+ Summaries), Insider Podcast, , Research Reviews, and More *Pro Tier:* All benefits of the Standard Tier + Live

Reconsidering Aging, Muscle Growth, Niacin Supplementation, Your Questions, and More Nov 19, 2023 03:58:50 *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders [Standard Tier]: https://bit.ly/PhysionicInsiders2 Join the Physionic Insiders [Pro Tier]: https://bit.ly/PhysionicInsidersPro *Standard Tier:* Access to the Premium Video Library, Full Study Analyses (+ Summaries), Insider Podcast, , Research Reviews, and More *Pro Tier:* All benefits of the Standard Tier + Live Se

Carnivore Diet, LDL Cholesterol, Fasting & Inflammation, Taurine on Longevity, and much more... Jul 28, 2023 03:03:00 *JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders [Premium]: https://bit.ly/PhysionicInsiders *JOIN THE COMMUNITY* Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity Table of Content 0:00 - Introduction 05:18 - Carnivore Diet 34:39 - LDL Cholesterol & Heart Disease 1:00:11 - Taurine on Longevity & Health 1:13:04 - One Meal a Day - Context Matters

Insulin on Fat Loss, GlyNAC for Anti-Aging, The Physionic Dream. Mar 18, 2023 02:46:16 JOIN MY PHYSIONIC SOCIAL NETWORK Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity Join the Physionic Insiders [Premium]: https://bit.ly/PhysionicInsiders HIRE ME FOR CONSULTING: https://bit.ly/3dmUl2H DONATIONS FOR A SCIENCE BASED CAUSE Patreon: patreon.com/PhysionicPhD WHERE ELSE IM ACTIVE: Email: http://bit.ly/2AXIzK6 Podcast: http://bit.ly/2PThKz0 Instagram: http://bit.ly/

Removing my John Campbell Video, High Intensity Health, Sweeteners break your Fast?, and More. Nov 5, 2022 01:21:41 JOIN MY PHYSIONIC SOCIAL NETWORK Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity Join the Physionic Insiders [Premium]: https://bit.ly/PhysionicInsiders HIRE ME FOR CONSULTING:  https://bit.ly/3dmUl2H    WHERE ELSE IM ACTIVE: Email: http://bit.ly/2AXIzK6 Podcast: http://bit.ly/2PThKz0 Instagram: http://bit.ly/2OBFe7i 0:00 - Introduction. 3:00 - Dr. John Cam

My High Blood Pressure Experience; Plastics impact on Insulin Resistance. Jun 26, 2022 01:30:06 Hi, in this episode, I cover a bunch of topics from my experience at the doctor, my own hypocrisy, some things I learned from you, and finally - the main topic of discussion: Insulin resistance and how plastics (phthalates) affect it. Oh, and if you're on Spotify or YouTube, it's now a video podcast, as well! MY COURSES, INSIDERS COMMUNITY, & CONSULTING - Join the ‘Physionic Insiders’ (Exclu

Issues with Nutrition Documentaries; Caffeine and Performance - They Don't Always Mix. May 28, 2022 01:25:23 Hi folks, in this episode I unintentionally discussed two topics. One, I planned on discussing, which was caffeine and it's performance effects in weight lifting and endurance. However, because I woke myself up to a nutrition documentary that I watched for 20 minutes or so before recording, I felt I had to get some things off my chest related to the second topic - nutrition documentaries. So, you

Nutrition & Pharmaceutical Therapies: Fat related Cancers Apr 14, 2022 01:26:52 In this episode, the first of a more relaxed, long form podcast style, we're going to dive into how fat relates to cancers - the mechanisms, but beyond that, the different therapies employed by pharmaceuticals, along with the use of nutrition to combat certain cancers. MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https:/

Let's Change how We do Things Here. Mar 31, 2022 00:14:21 I think you'd be better served if we change how we do things on the Physionic Podcast. MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physion

Carbohydrates slow Metabolism and Mitochondrial Breathing. Mar 25, 2022 00:19:16 In this episode, I'm going to begin the explanation as to what effects carbohydrates have on our metabolism, and one potential effect in our mitochondria. Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs34%5D-a-high-carbohydrate-diet-lowers-the-rate-of-adipose-tissue-mitochondrial-respiration Video: https://www.youtube.com/watch?v=7uBHNUSI6hI Previous Video on Carbs and Meta

An Exception to the Insulin Sensitivity Effects of Saturated Fat [Study 31] Mar 18, 2022 00:28:45 In this episode, we'll discuss a potential exception to the negative results on insulin sensitivity we've been discussing with the exposure to saturated fat. Study, Notes, & Amendments: https://www.physionic.org/examine/%5B31%5D-palmitate-acutely-induces-insulin-resistance-in-isolated-muscle-from-obese-but-not-lean-humans Video: https://youtu.be/ldUBG4-EJDo MY BOOKS, COURSES, VIDEO REQUESTS,

Mitochondria & Diabetes: How Nutrition Connects the Two. [Study 32] Mar 10, 2022 00:29:43 Hi all, in this episode, I'm going to describe to you how your nutrition, generally, affects your mitochondria in diabetes specific cells and how long term habits in nutrition can lead to diabetes (type 2). Enjoy. Video Version: https://youtu.be/x6EOhTzVKsE Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs32%5D-mitochondrial-dynamics-in-the-regulation-of-nutrient-utilization-

Your Nutrition affects your Mitochondria (Fasting vs Overconsumption) [Study 32] Mar 3, 2022 00:35:05 In this episode, we'll be diving into two ways your mitochondria change their "behavior" to the exposure to different nutrition situations (high vs low nutrient presence). Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs32%5D-mitochondrial-dynamics-in-the-regulation-of-nutrient-utilization-and-energy-expenditure Video: https://www.youtube.com/watch?v=KQBmtzT4VTU MY BOOKS, C

Saturated vs Unsaturated Fats: One is Worse for Insulin Resistance [Study 30] Feb 18, 2022 00:42:32 In this episode, we'll be going over a new study that wanted to find out the effects a saturated fat heavy consumption would have on insulin resistance and signaling against an unsaturated fat heavy consumption. Video: https://youtu.be/QfII7CANt14 Study: https://www.physionic.org/examine/%5Bs30%5D-dietary-palmitate-and-oleate-differently-modulate-insulin-sensitivity-in-human-skeletal-muscle MY

Unsaturated Fat to the Rescue: Insulin Signaling and Mitochondrial Health [Study 28] Feb 10, 2022 00:44:56 In this episode, we continue our quest for understanding the effect saturated fats have on muscle insulin signaling and mitochondrial health - however, beyond that, we'll be looking at how unsaturated fats may protect against the deleterious effects of saturated fat? Let's see.. Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs28%5D-different-effects-of-oleate-vs.-palmitate-o

Saturated Fat - Friend or Foe for Insulin Sensitivity and Mitochondrial Function? [Study 27] Feb 4, 2022 00:23:53 In this episode, I'm kicking off a new format that's more tailored to the podcast listeners, so there's less need to head to the video versions of the podcast to understand half of what I'm talking about. In this episode, we'll be discussing saturated fat (palmitate) and it's effects in relation to insulin signaling in muscle cells, as well as mitochondrial function. What are the effects? What are

Body Fat is lost from THIS - NOT HORMONES Nov 4, 2021 00:41:58 In this episode, I attempt to make sense of calories in vs out and reconcile that with the hormone argument for fat loss. Video Podcast: https://youtu.be/x1ZjjDzCdc0 MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT

THIS is how Mitochondria DESTROY your Cells. Oct 28, 2021 00:22:18 Mitochondria have a dark side, find out how. Video Podcast: https://www.youtube.com/watch?v=HPx7cv1I7eU MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i -

Long Term Effects from Fat Loss - Hormones, Weight Regain? [Study Breakdown] Oct 14, 2021 00:38:21 In this podcast, we look at a study that investigates how weight loss affects hormones and long term weight regain - is the deck stacked against you? Study: https://www.nejm.org/doi/full/10.1056/nejmoa1105816 Video Podcast: https://youtu.be/-t5d0S5MRwE 0:00 - Introduction 2:47 - Study Design 6:58 - Weight Loss & Weight Regain Results 9:45 - Long Term Hormonal Changes from Weight Loss 34:

Does Intermittent Fasting, WITHOUT WEIGHT LOSS, improve your Health? [Study Breakdown] Oct 6, 2021 00:26:20 How does intermittent fasting affect your health, even when you do not lose weight with it? Let's find out. Study: https://pubmed.ncbi.nlm.nih.gov/29754952/#:~:text=Men%20with%20Prediabetes-,Early%20Time%2DRestricted%20Feeding%20Improves%20Insulin%20Sensitivity%2C%20Blood%20Pressure%2C,Cell%20Metab. Video Podcast: https://youtu.be/1t0HUSlFNiQ MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING

You asked for it: My Lifetime Workout Routine, Health Habits, and Supplements Sep 22, 2021 00:40:45 Title says it all... Video Podcast: https://youtu.be/u4XirePJKfg MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2Pl

Sirtuins, Mitochondria, and Insulin Resistance Sep 15, 2021 00:46:28 In this episode, we'll be discussing how sirtuins play their role in mitochondrial health and insulin resistance. Scientific Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432223/ Video Podcast: https://youtu.be/M9INrzrfsu4   0:00 - Introduction 3:10 - Diabetes Background 8:30 - Mitochondria Background 13:33 - Mitochondria & Insulin Resistance 20:33 - Sirtuins 43:40 - Conclu

Creatine on Brain Health; Supplementation & an Alternative? Sep 8, 2021 00:31:24 In this episode, I summarize the content from a brand new scientific review that discusses the difference between creatine supplementation for the brain vs the rest of the body, as well as a possible alternative. Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916590/ Video Podcast: https://youtu.be/gltKZA6JQr0 MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine'

Compensation Theory: Why We should Stop Outrunning our Fat Sep 1, 2021 00:29:09 In this episode, I cover a study sent to me by a subscriber wherein the researchers discuss a new model for understanding metabolism through their self titled 'Compensation Hypothesis'. Study: https://www.sciencedirect.com/science/article/pii/S0960982221011209 Video Podcast: https://youtu.be/O7TY-HMZkKA MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https:/

Does your metabolism decline after 30? Aug 25, 2021 00:26:50 In this podcast, I'll be detailing a brand new study deeply investigating the decline in metabolism with age. Study: https://science.sciencemag.org/content/373/6556/808 Video Podcast: https://youtu.be/cXHxl8dPqG0 MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVH

Is Keto Right for Women's Health? [2 Studies] Aug 19, 2021 00:39:50 In this episode, we'll dive into two very similar studies trying to distinguish the effect of the ketogenic diet on cholesterol, blood sugar, insulin, and blood fats (triglycerides). Video Podcast: https://youtu.be/yx2OuoMZBFg Study A: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001988/pdf/nutrients-13-00814.pdf Study B: https://pubmed.ncbi.nlm.nih.gov/12949361/ 0:00 - Introduction 3:40 - St

16/8 Intermittent Fasting, without Calorie Counting, on Weight & Health Aug 12, 2021 00:29:30 In this episode, we'll dissect a study wherein the researchers attempt to find out how an unrestricted intermittent fasting protocol works for overweight individuals in aspects of weight, muscle, metabolism, and cardiovascular outcomes like cholesterol, blood sugar, insulin, and so on. Video Podcast: https://youtu.be/TjEKr7ysbfI Study: https://pubmed.ncbi.nlm.nih.gov/32986097/ MY BOOKS, COURSES,

Questions & Answers: Protein Threshold, Origin of CoVID, Protein on Lifespan, and More. Aug 5, 2021 00:24:52 This week, I return by simply answering questions you guys sent me on Instagram and YouTube. MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Ph

Protein for Optimal Muscle Growth: Type, Timing, Amount, and More Jul 22, 2021 00:52:33 In this episode, I cover a scientific review on the literature of protein for muscle growth. We'll be covering protein total amount, timing, type, differences in men and women, aging, and more. Enjoy. Video Podcast: https://youtu.be/7h-kLKmknEo Scientific Review: https://link.springer.com/article/10.1007/s40279-019-01053-5 MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Cr

Elevated Blood Fats Change our Mitochondria Behavior & Autophagy Jul 15, 2021 00:29:14 In this episode, we investigate how elevated blood fats change how our mitochondria "behave" and its affect on autophagy. Video Podcast: https://youtu.be/g6JJzVkYM7I Study: https://www.sciencedirect.com/science/article/abs/pii/S0026049521001037 MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Conte

Saturated vs Unsaturated Keto on Cholesterol & Insulin Sensitivity [Starting to get Answers] Jul 8, 2021 00:21:56 In this podcast, I dive deeper into yet another study comparing the ketogenic diet for blood cholesterol, with the added bonus of briefly touching on insulin sensitivity. In this episode, we start to recognize the key difference between a healthy ketogenic diet and an unhealthy ketogenic diet. Study: https://pubmed.ncbi.nlm.nih.gov/15070924/ Video Podcast: https://youtu.be/KEcyW496KGA MY BOOKS,

Ketogenic Diet increases Cholesterol in Healthy Women Jul 1, 2021 00:24:23 In this episode, we'll be going again into the ketogenic diet, but the context hath changed as the people being tested are healthy and young, non-overweight, unlike previous studies. There are some other caveats, as well, that we'll go into, so buckle up and let's dive in. Study: https://pubmed.ncbi.nlm.nih.gov/30408717/ Video Podcast: https://youtu.be/bX1cax3zvfQ MY BOOKS, COURSES, VIDEO REQUE

Intermittent Fasting + Exercise on Muscle, Fat, Blood Sugar, Inflammation & More Jun 24, 2021 00:40:34 In this episode, we dive into a study looking at how 16 hour intermittent fasting affects a variety of health outcomes when paired with resistance training in non-beginner lifters. Study: https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-016-1044-0 Video Podcast: https://youtu.be/2B99DJwPMCk MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' B

Overweight? High Cholesterol? High Blood Sugar? Keto it away. Jun 17, 2021 00:26:31 In this episode, the 'keto hater' takes on a study that simply investigates the effects from the ketogenic diet in bodyweight, cholesterol, and blood sugar in people who are overweight. Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716748/pdf/ecc09200.pdf Video Podcast: https://youtu.be/bsH1qubGSB8 MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https:

The End Replication Problem (Telomeres) & Cellular Senescence Jun 10, 2021 00:30:39 In this episode, we'll be beginning our look at senescent cells, how and why they occur, as well as the main drivers of senescence in aging and disease. Video Podcast: https://youtu.be/NcBpJv5WIhY Scientific Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748990/pdf/JCB_201708092.pdf MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN

How do Saturated Fats affect Mitochondria? Jun 3, 2021 00:21:07 In this episode, we'll be discussing how different types of saturated and unsaturated fats impact mitochondria in our muscle cells. Video Podcast: https://youtu.be/2T9I1FmlFyE Study: https://link.springer.com/content/pdf/10.1007/s00125-005-1895-z.pdf MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H -

The 'Keto Damages the Heart' Critique, and My Nutrition May 27, 2021 00:34:25 In this episode, I discuss some of the valid and non-valid (by my estimation) critiques of the recent ketogenic diet study I covered on the YouTube channel. I also discuss the nutrition style that I follow, specifically. Video Podcast: https://youtu.be/eE2QpdRSeFY Keto Damages the Heart Video: https://youtu.be/CAkjoT28yZw Keto Damages the Heart Podcast: https://youtu.be/lpns8gfR3H8 MY BOOKS, C

Emilin Deficiency leads to High Blood Pressure May 20, 2021 00:39:44 In this episode, I discuss a study looking at how a protein (Emilin) and a molecule (TGF-beta) create a scenario in which high blood pressure occurs in animals *and* in the same effect is seen in humans with high blood pressure. Study: https://pubmed.ncbi.nlm.nih.gov/30354220/ Video Podcast: https://youtu.be/88GqvZ2XjrM MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creat

Why Cancer feeds on Sugar May 12, 2021 00:34:15 In this episode, I discuss how, and potential reasons why, cancer cells feed off sugar/glucose. Scientific Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783224/ Video Podcast: https://youtu.be/vszypCVgpaE MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/

How does Alcohol affect your Muscle Growth? Let's discuss the Data. May 5, 2021 00:25:40 In this episode, we go into a study that investigates if alcohol affects our muscle growth potential by specifically looking at muscle protein synthesis, as well as some proxy markers of protein breakdown. Study: https://pubmed.ncbi.nlm.nih.gov/24533082/ Video Podcast: https://youtu.be/CaRPAx9gL4U MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.

I Published a Study (On a New Mechanism for Autophagy) Apr 28, 2021 01:08:03 This is an involved one, but if you care to join me as I explain my recent publication with my lab wherein we discover and describe a new pathway by which autophagy is mediated in cells, then you'll learn some cutting edge science. My Study: https://www.researchgate.net/publication/350870898_Parkin-independent_mitophagy_via_Drp1-mediated_outer_membrane_severing_and_inner_membrane_ubiquitination

A Medical Research Lecture on Heart Aneurysms [Marfan Syndrome] Apr 14, 2021 00:52:24 This podcast gets really nitty gritty in that it discusses the intracellular signaling pathways and the association between smooth muscle cells and a protein rich foundation known as the extracellular matrix - what causes this weakness in the aorta of the vascular system leading to aneurysm formation? Find out. Study: https://youtu.be/YlQtTdj2eLo Video Podcast: https://youtu.be/YlQtTdj2eLo MY B

Excessive Exercise changes how our Mitochondria behave? [Mitochondrial Dynamics] 2 Apr 7, 2021 00:36:53 In this episode, we finish up from last week by discussing how mitochondrial "behavior" is affected by excessive exercise, as well as its impact on mitochondrial reactive oxygen generation, which can cause damage to our cells. Study: https://www.sciencedirect.com/science/article/abs/pii/S1550413121001029?via%3Dihub MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine

Is too much exercise detrimental to our mitochondria and blood sugar regulation? Mar 31, 2021 00:59:01 In this episode, I cover a brand spankin' new study wherein the researchers attempt to answer the question of overdoing exercise and its impact on muscle mitochondria, as well as blood sugar regulation. Study: https://www.sciencedirect.com/science/article/abs/pii/S1550413121001029?via%3Dihub Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagra

Weight Loss and its affect on Metabolic Adaptation Mar 24, 2021 00:44:24 In this episode, we take a look at a study that investigates the impact weight loss/calorie restriction has on metabolic adaptation; we also briefly discuss the idea of metabolic "damage". This is one of a few episodes that I'll be using to cover the topic of metabolic adaptation. Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328781/?fbclid=IwAR3WSvSpNLzgnwfGh_xyAEx4Txh9z91LnjbW2CFrbbzSS0

Ketogenic Diet & Ketosis leads to Heart Cell Death [Study Breakdown] Mar 17, 2021 00:39:24 In this episode, I take us on a brief breakdown of a study looking at the ketogenic diet and its impact on heart cell death, heart size, and mitochondrial content. Some intriguing, potentially alarming, results here, but we'll see what interpretations we can really make on this data - dive in with me! Study: https://www.nature.com/articles/s41392-020-00411-4 Books, Courses, and Hire Me: www.phys

Burning More Fat DOES NOT mean losing more BODY FAT Mar 10, 2021 00:33:27 In this episode, I attempt to make it as clear as possible, by comparison of high fat/keto to high carbohydrate diets and how they differ in their ability produce body fat loss, although one promotes greater fat burning/oxidation. Video Podcast (available at 10am ET): https://youtu.be/Ns0tXvLI-OI Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Ins

Metabolic Flexibility: Switching from Carbs to Fat, and Back Again Mar 3, 2021 00:25:16 In this episode, I give a bit of a higher level view on metabolic flexibility - what is it? Why is it important? Instances of it? How to improve it? That's all covered in this podcast - enjoy! Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6

Does Water Fasting increase our Mitochondria? Feb 17, 2021 00:17:14 In this episode, I briefly cover certain aspects of a study that looks into how effective fasting, specifically multi day water fasting, affects our mitochondrial content in our cells (muscle). Video Podcast: https://youtu.be/KMU1OcGjjLw Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6

I ran an Experiment on Myself [Muscle Maintenance] and Your Questions Answered Feb 10, 2021 00:28:40 In this episode, I cover more detail on an experiment I decided to try on myself over the last 10 months wherein I try to maintain my muscle with minimal effort. I answer questions from 10 people who wrote questions out on how I pulled it off, as well as other questions related to fat loss and muscle perseveration. Video being Discussed [I Ran an Experiment on Myself]: https://youtu.be/qtim_tXkV

Mutations that affect Muscle Fusion Feb 3, 2021 00:48:15 In this podcast, we'll be going over a presentation I gave in one of my courses on Muscle Biology - specifically, how certain mutations in a gene can impede muscle cells' ability to fuse, and on top of that, why some people survive it and why others do not. Study: https://www.nature.com/articles/ncomms16077 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/

You Can't Have it All [Lifespan vs Health span] Jan 27, 2021 00:22:43 There is no human condition wherein you will be at peak form in multiple areas. Much like the idea of the generalist vs the specialist - your body can't be a specialist in all ways, and in the same vein, there is no diet that will be the "ultimate" diet that will help you achieve peak-ness in all areas. The discussion of lifespan vs health span is a great example of that, as well as the idea of gr

Fasting and Calorie Counting: Which stimulates Hunger Hormones? [Leptin, MSH, AgRP] Jan 20, 2021 00:21:28 In this content, I dive into a study looking into three hunger related hormones and the effect water fasting and calorie counting have, in obese and lean individuals, on three hunger hormones - leptin, melanocyte stimulating hormone (MSH), and Aguiti Related Protein (AgRP). Does fasting stimulate these hormones or does calorie counting? Does obesity play a factor? Find out! Study: https://pubmed.

Fractalkine: A marker for Alzheimer's and Neuroinflammation Jan 13, 2021 00:32:43 In this episode, I discuss a molecule I ran across when listening to the Joe Rogan Experience. This molecule, known as fractalkine, has some unique characteristics and potential implications in a series of different diseases and brain related health outcomes - mostly related to inflammation in the brain. Review: https://pubmed.ncbi.nlm.nih.gov/26084002/ My Creatine Book and Course: http://bit.ly

Three UNKNOWN Benefits of Creatine [Muscle, Brain, and Inflammation] Jan 6, 2021 00:22:14 In this episode, we briefly discuss three ways that creatine positively affects us in muscle, the brain, and inflammation. I also introduce my first paid content that I spent most of 2020 working on, as well as a new website for your viewing pleasure - it was a busy 2020 for me! Creatine Book and Course: https://www.physionic.org/booksandcourses Books, Courses, and Hire Me: www.physionic.or

ASP: The Ketogenic Fat Storage Hormone Dec 30, 2020 00:28:51 In this episode, I go into a bit more detail on a topic I've just started releasing content on (in video form). This subject is on a hormone that also leads to fat storage, much like insulin, yet many keto espousing gurus either ignore or are not aware of it; this is convenient, since this hormone is stimulated by fat consumption, not carbohydrate consumption (the exact anti-thesis to insulin).

Chrono nutrition: Intermittent Fasting improves Insulin Sensitivity INDEPENDENT of Calories Dec 16, 2020 00:30:51 In this episode, we'll be diving head long into a study investigating the first slice of "chrono nutrition" on Physionic. I love this study, because they do several things really well and give us some clear answers regarding intermittent fasting and its impact on insulin sensitivity *independent* of calorie intake (finally!). Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528549/pdf/nqaa19

Three Mechanisms of Muscle Growth Dec 9, 2020 00:32:54 In this podcast, I decided to jump into an area I've created a decent amount of isolated content and put it into one place. I go into a bit of depth, but not complete depth into three mechanisms of muscle growth - from the classic "muscle damage" to metabolic stress. Knowing this information can easily help us understand how to create training programs that aren't centered around old fashioned thi

Nutrition for Depression: Obesity, Epigenetics, and Tryptophan (yes, the stuff in turkey) Dec 2, 2020 00:30:26 In this episode, we'll be diving into our third and final part of our "Nutrition on Depression" podcast wherein we'll be touching on depression's link in obesity, epigenetics, and the amino acid tryptophan (the same stuff found in turkey, and many other foods). Hopefully you find some, if not all, the information useful and informative. If you'd like to see the visuals, check out the video version

Nutrition for Depression: The HPA Axis, Brain Derived Neurotrophic Factor, and More [Part 2] Nov 25, 2020 00:47:50 In this episode, we continue our dive into these different nutrients and nutritionally linked reasons why people have worsening depression and what to do against it, nutritionally. This is part 2 of a 3 part podcast series discussing nutrition and its relationship to depression. I'll go into the microbiome, cortisol release from the HPA axis, and BDNF on brain cell growth. Study: https://www.nat

Nutrition on Depression: Nutrients that Help [Part 1] Nov 18, 2020 00:58:25 In this episode, I begin with part 1, wherein we'll be discussing how depression is linked to inflammation, mitochondrial dysfunction, and oxidative stress, as well as several nutrients that can help reduce these effects negatively affecting mental health. Study: https://www.nature.com/articles/s41380-020-00925-x Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: b

Fasting on Skin Health & Skin Aging: A Review Nov 11, 2020 00:42:35 In this episode, I'll be trying my best to make sense of a pretty "all over the place" scientific review that attempts to make sense of how fasting (and calorie deficits) affect skin health, as well as aging. Video Version: https://youtu.be/ihV7hOhAk58 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AX

Caffeine: Does it make us less insulin sensitive? Nov 4, 2020 00:39:56 In this episode, we dive into a study that investigates the effect caffeine has on insulin sensitivity, but also on a few other parameters, like blood pressure, catecholamines, and free fat. Study: https://care.diabetesjournals.org/content/25/2/364.full-text.pdf Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List:

Creatine on Fat Metabolism, Thermogenesis, ft. Alec Chaves Oct 28, 2020 01:07:59 In this episode, I have the absolute pleasure of welcoming a good friend of mine back to the podcast to discuss a paper he picked out looking at a unique way that creatine affects our fat cells - specifically, the mitochondria within fat cells. Creatine Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656041/ Alec's Podcast (Physiology Forum): Apple: https://podcasts.apple.com/us/podcast/t

Women vs Men: Who Gains Muscle Strength Faster? Oct 21, 2020 00:29:39 In this episode, we dive into an extremely simple study that investigates how quickly men and women, compared against one another, gain muscle strength from a resistance training program. Not only that, it touches on some interesting perspectives related to hormones and how the lack of testosterone in women may not be as detrimental as one might imagine - tune in and find out! Study: https://www.

10 Day Water Fast INCREASES Inflammation, but is that bad? Oct 14, 2020 00:41:57 In this podcast, we'll be going over a study that touched on an interesting discovery between fat cells and our immune system when a person undergoes an extended (10 day) water fast. Study: https://reader.elsevier.com/reader/sd/pii/S2212877820301563?token=8C7127DDF72DF25D84C3810C2A6673547BFB183F9FA75E6692EA9472DCC7CC12A193097F7212AC3D993955B07CAA1405 Books, Courses, and Hire Me: www.physionic.o

Does Saturated Fat increase Cholesterol and damage your Liver? Oct 7, 2020 00:57:57 In this episode, I do a deep dive into a study that finally tries to answer if saturated fat increases our cholesterol levels, independent of weight gain. Not only that, it also investigates the impact it has on the liver in terms of fatness - does it cause fatty liver disease? Study: https://academic.oup.com/jcem/article/104/12/6207/5540968 Books, Courses, and Hire Me: www.physionic.org YouTube

Alternate Day Fasting on Cholesterol, Muscle, and Fat-centric Hormones Sep 30, 2020 00:45:20 In this episode, I'll be taking you through a study on alternate day fasting and its affects on cholesterol, fat, muscle, and three unique hormones - all in people without cardiovascular issues, which makes this study that much more unique. Study: https://onlinelibrary.wiley.com/doi/10.1038/oby.2010.54 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIO

A Light Review of Body Weight "Set Point" Theory Sep 23, 2020 00:53:14 In this podcast, I brush across a variety of concepts and information related to the hypothesis of "body weight set point" that espouses the idea that the body sticks to roughly the same set point in body weight when we attempt to change our weight, the body fights against that imposed change - why? What mechanisms and reasons might there be? Is there a better theory? Study: https://www.ncbi.nlm.

The Consequences of Extreme Dieting & Low Body Fat Sep 16, 2020 00:54:02 In this episode, I'll be walking us through a case study that recently released on a natural bodybuilder that was followed and measured by researchers for 12 months. They wanted to know how extreme dieting to low single digit body fat would affect testosterone, thyroid hormone, muscle mass, metabolism, and more, and if there were any negative effects, how long would it take to recover? Study: htt

High Fat vs High Carb Diets - Which is better for Health? (Blood Pressure, Cholesterol, Leptin, and more) Sep 9, 2020 00:31:28 In this episode, we'll be getting into a study looking at the ketogenic (high fat) diet and its comparison to a calorie restricted low fat diet on various markers of health. Study: https://academic.oup.com/jcem/article/88/4/1617/2845298 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6

Can you get coronavirus more than once? Yes. [New Study] Sep 2, 2020 00:23:12 In this episode, I'll be explaining, based on a brand new case study, why the risk for re-infection is present, and what this means for the future of vaccines and herd immunity. Study: https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa1275/5897019 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: b

Do Artificial Sweeteners and Sugar cause Weight Gain and Cravings? A Study weighs in. Aug 26, 2020 00:25:51 In this episode, we cover a study investigating if 4 different artificial sweeteners (Sucralose, RebA, Saccharin, and Aspartame) cause weight gain, insulin issues, spikes in blood sugar, cravings, and more. Study: https://academic.oup.com/ajcn/article/109/5/1288/5475055 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Emai

Supplementing Coenzyme Q10 and migraines... is there a benefit? Aug 19, 2020 00:22:25 In this episode, we'll be looking at a brief clinical trial looking at coenzyme Q10 (CoQ10, ubiquinone) and its affect on migraines in clinically evaluated migraine sufferers. If CoQ10 works, how much was used? How beneficial is it? Are there caveats? All that and more is covered here. Study: https://www.semanticscholar.org/paper/Efficacy-of-coenzyme-Q10-in-migraine-prophylaxis%3A-A-S%C3%A1ndor-

Is Intermittent Fasting hurtful to Heart Health? Maybe. Aug 12, 2020 00:28:27 In this episode, we'll be diving into a study investigating the role intermittent fasting has on a series of health markers, but specifically on cholesterol and blood pressure - it's not all good news, or is it? Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645638/ Books, Courses, and Hire Me: www.physionic.org YouTube: http://bit.ly/2JUjXVt Facebook: http://bit.ly/2PlIOaB Instagram: http

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