DiabetesBio
DiabetesBio features co-hosts Darleen Sandoval, Kirk Habegger, and Kevin Williams interviewing authors of editor-selected biomedical research articles featured in the journal Diabetes. The podcast highlights significant advances in diabetes research by engaging directly with the scientists behind the studies. Listeners gain insights into the latest findings and the broader implications for diabetes care and treatment.
Episodes
A Diabetes Symposium Special, with John Ussher on Diastolic Dysfunction, Norbert Stefan on MASLD, and Julia Critchley, Tess Harris, & Liza Bowen on Increased Risk of Infections in People Living with Diabetes
Welcome to the August 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the August 2026 issue of Diabetes. This special episode will highlight articles from the Diabetes Symposium, "Non-Classical C
Special Edition: Highlights from the ADA's 2026 Scientific Sessions
In this special crossover episode, recorded live at the American Diabetes Association's Scientific Sessions in New Orleans, the hosts of the ADA's professional podcasts—DOC Updates, Diabetes Care "On Air", DiabetesBio, and The Points of CARE—come together to discuss key highlights and groundbreaking research presented at the 2026 meeting. They share expert insights across the bench-to-bedside spec
Jennifer Thompson & Taylor Scheidl on Estrogen, Hyperplastic Adipose Expansion and Preserving Adipose Progenitor Cell Availability in Subcutaneous Depots of Female Mice, plus "Sweet Talk" with ghrelin hormone researcher Jeffrey Zigman
Welcome to the July 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the July 2026 issue of Diabetes. 5:40 Kirk welcomes Jennifer Thompson, PhD, Associate Professor in the Department of Biochemist
T-Cell Memory and Metabolic Response to Weight Cycling, Gut-Derived FGF15 Modulating Lean Mass, Bone, and Bile Acid Responses to Weight Loss, plus "Sweet Talk" with Myers, past recipient of the Outstanding Scientific Achievement Award
Welcome to the June 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the June 2026 issue of Diabetes. 7:00 To discuss this issue's Paper of the Month, our hosts speak with Alyssa Hasty, PhD, Vice
Sushant Bhatnagar on Maintaining Glucose Homeostasis via Tomosyn-2, Vladimer Darsalia on insulin resistance and stroke outcomes, plus "Sweet Talk" with Timo Mueller, recipient of the 2026 Outstanding Scientific Achievement Award
Welcome to the May 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the May 2026 issue of Diabetes. 6:45 Our hosts speak with Sushant Bhatnagar, PhD, an associate professor in the Division of Endo
Fabriciova & Pavlinkova on Sex Differences in Diabetes Progression, Delgado-Corrales & Kim on Children with Islet Autoimmunity, plus "Sweet Talk" with Lora K. Heisler, recipient of the 2018 Outstanding Scientific Achievement Award.
Welcome to the April 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the April 2026 issue of Diabetes. 5:30 Our hosts speak with Valeria Fabriciova, a PhD student in the group of Gabriela Pavlink
Matthew Merrins on Amino Acid Sensing, Noah Levi & Alejandro Caicedo on controlling pancreatic cell function through muscarinic receptor signaling, plus "Sweet Talk" about the upcoming Scientific Sessions with Mark Atkinson
Welcome to the March 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the March 2026 issue of Diabetes. 8:15 Kirk speaks with Matthew Merrins, PhD, Joseph F. Hoffman Professor of Cellular and Mole
Wilson & Moore on B Lymphocytes and eroding islet tolerance in type 1 diabetes, Mittendorfer on the effects of marked weight loss on postprandial glucose disposal in type 2 diabetes, plus "Sweet Talk" with Sir Stephen O'Rahilly
Welcome to the February 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the February 2026 issue of Diabetes. 6:10 To discuss this issue's Paper of the Month, our hosts are joined by authors Chris
Masaya Oshima on the effects of killing human β-cells by CD8+ T cells and "Sweet Talk" with Sarah Stanely on the neural regulation of blood glucose in acute stress
Welcome to the January 2026 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the January 2026 issue of Diabetes. 17:40 After sharing their predictions for the new year, our hosts are joined by Masaya O
Bergman on altering lipid localization and adipose tissue cellular composition through weight loss and exercise, Walters, Castro-Gutierrez, Mukherjee & Russ on HLA immune presentation on Human β-Cells, metabolic "Sweet Talk" with Banks, Holman, & Lan
Welcome to the December 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the December 2025 issue of Diabetes. 13:10 After discussing their favorite interviews of the past two years, our hosts are
Kaylia Reynolds and Nora Franceschini on diabetes genetic clusters, Stephanie Holm & Christoffer Clemmensen on sustained weight loss with LEAP2 & Semaglutide, plus "Sweet Talk" with Banting Medal recipient Jens Juul Holst
Welcome to the November 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the November 2025 issue of Diabetes. 6:00 In the first segment, our hosts are joined by Kaylia Reynolds, MS and Nora France
Cacciottoloon on glucagon receptor deficiency & early-onset hepatic steatosis, "Sweet Talk" on childhood obesity with Nadeau & Cartwright, plus a special segment: speaking to kids directly with their questions about diabetes and obesity
Welcome to the October 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the October 2025 issue of Diabetes. 5:50 In the first segment, our hosts are joined by Tessa M. Cacciottolo, PhD, a Chain Fl
Quarta on GLP-1-mediated targeting of inflammation and obesogenic memory in mice, Hsueh on dulaglutide and hepatic steatosis in obesity via a weight-independent mechanism, & "Sweet Talk" with Pathway to Stop Diabetes Award recipient Alexander Nectow
Welcome to the September 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the September 2025 issue of Diabetes. 5:25 In the first segment, our hosts are joined by Carmelo Quarta, PhD, a principal
Special Edition: Highlights from the ADA's 2025 Scientific Sessions
In this special crossover episode, recorded live at the American Diabetes Association's 85th Scientific Sessions in Chicago, the hosts of ADA's professional podcasts—Diabetes Core Update, Diabetes Care "On Air", and DiabetesBio—come together to discuss key highlights and groundbreaking research presented at the 2025 meeting. They share expert insights across the bench-to-bedside spectrum, inc
A special extended "Sweet Talk" episode on the debate between GIP receptor agonism and GIP receptor antagonism, with Daniel Drucker, OC, MD, FRCPC, FRSC, FRS, and Jonathan Campbell, PhD.
Welcome to the August 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the August 2025 issue of Diabetes. 6:55 For this month's episode, a special extended edition of "Sweet Talk," exploring the d
Suganami & Tanaka on regulation of adipose tissue fibrosis, Watanabe on genetic variations in GCKR & PNPLA3 regulating metabolic balance across the liver, "Sweet Talk" with the 2025 Albert Renold Distinguished Career Award recipient Barbara B. Khan
Welcome to the July 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the July 2025 issue of Diabetes. 6:50 In the first interview segment, our hosts discuss July's Paper of the Month, titled "Nov
Okamoto & Bao on hepatic PKA mediating liver and pancreatic α-cell cross talk, Kowalski on the effect of small blood glucose increases on endogenous glucose production, Sweet Talk with the 2025 Outstanding Scientific Achievement Award recipient Kajimura
Haruka Okamoto & Kehan Bao on hepatic PKA mediating liver and pancreatic α-cell cross talk, Greg Kowalski on the effect of small blood glucose increases on endogenous glucose production, and "Sweet Talk" with the 2025 Outstanding Scientific Achievement Award recipient Shingo Kajimura. Welcome to the June 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship rese
Michael Rickels on predicting metabolic outcomes through beta cell secretory capacity, Mark Atkinson on the ADA's upcoming Scientific Sessions, and 2025 Banting Medal recipient Steven Kahn
Welcome to the May 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the May 2025 issue of Diabetes. 6:25 In the first interview segment, our hosts discuss May's Paper of the Month, titled "β-Cell
Jennifer Bruin & Lahari Basu on cisplatin exposure and the dysregulation of insulin, Amit Majithia on AF-1 domain inhibition as an insulin sensitization target, and a Sweet Talk special remembrance with Maren Laughlin, Julio Ayala, and Shawn Burgess
Welcome to the April 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the April 2025 issue of Diabetes. 6:30 In the first interview segment, our hosts discuss an article titled "Cisplatin Exposur
Anne Gresch & Martina Düfer on resolving spatiotemporal electrical signaling within the islet, Delnaz Roshandel on the genetics of C-peptide and age, and a Sweet Talk history lesson with Jeffrey Flier & Christopher Newgard
Welcome to the March 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the March 2025 issue of Diabetes. 3:20 In the first interview segment, our hosts discuss the Paper of the Month, "Resolving
Francis C. Lynn on tracking insulin- and glucagon-expressing cells, David C. Wraith & Michael J. Price on antigen-specific immunotherapy for T1D, and Sweet Talk with Bret H. Goodpaster
Welcome to the February 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the February 2025 issue of Diabetes. 3:55 In the first interview segment, our hosts our joined by Francis C. Lynn, BSc Ph
Philipp Scherer & Joel Elmquist on the interplay between the brain and adipose tissue and Jonathan Flak on the brain's role in glucose regulation, energy balance, and bodyweight control.
Welcome to the January 2025 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the January 2025 issue of Diabetes. 2:00 In a special format for the first episode of the new year, our hosts introduce a
Stilgenbauer & Sadagurski on the link between airborne pollutants and metabolic disease, Petersen on the effect of weight loss on skeletal muscle bioactive lipids, and Page & Alves on the neurodevelopmental pathways to obesity and type 2 diabetes.
Welcome to the December 2024 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the December 2024 issue of Diabetes. 0:55 In celebrating the one-year anniversary of DiabetesBio, our hosts highlight a fe
Maxwell and Grillo on the link between feeding behaviors and leptin activation of dorsal raphe neurons, Fruttiger on microvascular damage and neurodegeneration in early diabetic retinopathy, and Yeo on the genetics of metabolic health.
Welcome to the November 2024 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the November 2024 issue of Diabetes. 3:45 After a quick rundown of our hosts' Halloween plans, this month's episode begins
Grøndahl on glucagon clearance decrease in kidney disease despite preservation in liver cirrhosis, Barra and Russ on cryopreservation of stem cell–derived β-like cells, Sunilkumar and Dennis on targeting REDD1 to combat diabetes complications, & more!
Welcome to the October 2024 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the October 2024 issue of Diabetes and interview a Pathway to Stop Diabetes award winner. 4:05 This month's episode begins
Jose Ortiz and Teresa Ku on trefoil factor 2 expression by pancreatic acinar cells, Adrian Vella on the effect of diabetes-associated variation in TCF7L2 on islet function, Matthew Webber on being a Pathway to Stop Diabetes awardee, and more!
Welcome to the September 2024 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the September 2024 issue of Diabetes and interview a Pathway to Stop Diabetes award winner. 4:20: Darleen and Kirk ar
Scientific Sessions Reviewed by ADA Podcast Co-Hosts! In this special episode, the co-hosts of DiabetesBio, Diabetes Care "On Air," Diabetes Core Update, and Diabetes Day by Day discuss highlights from the ADA's 2024 Scientific Sessions
Welcome to a very special episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. While this podcast usually focuses on the research published in Diabetes, this unique episode focuses on the incredible scholarly content of the 84th Scientific Sessions, which took place 21–24 June in Orlando, FL. Alice Cheng, MD, FRCPC, co-host of Diab
Inbal Caspi and Danwei Huangfu on glucose transporters in human glucostat, Deepthi Mallela discusses the genetics of bile acids and their association with diabetes, Bernard Thorens and David Hodson revisit a 1993 "Classic" on GLP-1, and more!
Welcome to the August 2024 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the August 2024 issue of Diabetes. 2:39: Darleen and Kirk are joined by Dr. Inbal Caspi and Dr. Danwei Huangfu, lead a
Jordan Wright on the exocrine pancreas, Lisa Smeehuijzen on circulating monocytes for individuals with obesity and insulin resistance, Sweet Talk with this year's Banting Medal winner, Rury Holman, and more!
Welcome to the July 2024 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the July 2024 issue of Diabetes. 4:31: Darleen and Kirk are joined by Dr. Jordan J. Wright, first author of the Paper of t
DeFronzo on a novel renal-hepatic axis in endogenous glucose production, arguments for and against the current model of glucose regulation of β-cell KATP channels from Rutter and Sweet (for) and Merrins and Kibbey (against), and more!
Welcome to the June 2024 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the June 2024 issue of Diabetes. 2:27: Darleen and Kirk are joined by Dr. Ralph A. DeFronzo, senior author of the article "
Devi Kasinathan, Zheng Guo, and Dax Fu on autoimmune diabetes, Jennifer Lee and Rebecca Salzo on WIN ADA, Olga Gupta and Rana Gupta on a "Classic" article about regional adiposity, and more!
Welcome to the May 2024 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the May 2024 issue of Diabetes. 5:06: Darleen and Kirk are joined by Drs. Devi Kasinathan, Zheng Guo, and Dax Fu, authors t
Sebastian Kalamajski on genetic aspects of adiposity-related traits; Yuval Dor on DNA methylation–based assessment of pancreas and islet cells; and Carmella Evans-Molina on the role of calcium in regulating insulin secretion.
Welcome to the April 2024 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the April 2024 issue of Diabetes. 2:55: To kick things off, Darleen and Kirk are joined by Dr. Sebastian Kalamajski (Lund
Bonus Sweet Talk episode with Christopher Newgard and Louis Philipson about the ADA's Pathway to Stop Diabetes initiative, Céline E. Riera on her Pathway award-winning research, and more!
Welcome to the special Sweet Talk March 2024 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. Our host is Dr. Kevin Williams. 1:00 Sweet Talk, part 1. Kevin introduces the guests for the first part of Sweet Talk, Dr. Christopher Newgard from Duke University Medical Center and Dr. Louis Philipson from the University of Chicago
Harry Cutler and David James on using a dual tracer test to identify insulin resistance in mice, Lori Sussel on PTPN2 regulation of metabolic flux, a preview of a special Sweet Talk episode this month, and more!
Welcome to the March 2024 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the March 2024 issue of Diabetes. 1:15 Before getting underway with this week's interviews, Kirk gives a quick shout-out t
Satya Dash on erythritol and cardiometabolic disease; Jeffrey Hodgin and Alan Attie on genetic analysis of obesity-induced diabetic nephropathy in BTBR mice; and revisiting Frans Schuit's 1998 "Classic in Diabetes" on glucagon biology
Welcome to the February 2024 episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the February 2024 issue of Diabetes. 2:25: To kick things off, Darleen and Kirk are joined by Dr. Satya Dash of Univers
Introducing DiabetesBio! A chat with editor David D'Alessio, discussing fatty acids and GDF15 with "Paper of the Month" author Gregory Steinberg, and remembering Daniel Porte Jr.
Welcome to the premiere episode of DiabetesBio—the American Diabetes Association's podcast for its flagship research publication, Diabetes. In each episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams will discuss the latest and greatest content in Diabetes. The team kicks off this first episode with some brief introductions before passing the mic to Diabetes editor-in-
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