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Core IM | Internal Medicine Podcast

Core IM | Internal Medicine Podcast

Core IM Team 216 episodes Nov 11, 2026

Core IM is an internal medicine podcast that offers several series: '5 Pearls' delivers clinically relevant pearls, 'Mind the Gap' explores the reasoning behind medical practices, 'Gray Matters' focuses on management reasoning, 'Hoofbeats' dissects clinical reasoning, and 'At the Bedside' addresses everyday challenges in medicine.

Episodes

#223 Amyloidosis Presentation: Gray Matters Segment
#223 Amyloidosis Presentation: Gray Matters Segment Nov 11, 2026 26:38 “Could amyloidosis be the reason behind a patient’s unexplained symptoms?” This episode explores the clinical clues that should prompt clinicians to consider AL amyloidosis and recognize patterns of organ involvement that may otherwise be easy to overlook. Learn how to connect the findings, spot important red flags, and bring amyloidosis into your differential diagnosis.🔹Sponsor: ACP MKSAP Oakston
#222 AFib Stroke Prevention: WATCHMAN, DOACs, and the CHAMPION-AF Trial | Beyond Journal Club Segment with NEJM Group
#222 AFib Stroke Prevention: WATCHMAN, DOACs, and the CHAMPION-AF Trial | Beyond Journal Club Segment with NEJM Group Oct 28, 2026 31:56 If your patient asks you about a left atrial appendage closure device, what should you tell them?   In the latest episode of the Beyond Journal Club podcast from CORE IM and NEJM Group, the hosts will help you:  Understand the trade-offs: stroke prevention, bleeding, procedural risks, and medications afterward.  Build clinical judgment: weigh which approach may better serve the individual patient,
#221 Colon Cancer Screening After Age 75 | 5 Pearls Segment Part 3
#221 Colon Cancer Screening After Age 75 | 5 Pearls Segment Part 3 Oct 21, 2026 17:06 “Should you stop screening for colorectal cancer (CRC) at 75?” This episode explores how to individualize screening decisions based on life expectancy, prior colonoscopy findings, and procedural risks. Learn how to navigate these nuanced conversations, avoid age-based assumptions, and use strategies like mailed FIT kits and offering screening choices to help more patients get screened.🔹Sponsor: Se
#220 Colon Cancer Screening Nuances: 5 Pearls Segment Part 2
#220 Colon Cancer Screening Nuances: 5 Pearls Segment Part 2 Oct 8, 2026 21:09 “What’s the best way to screen?” This episode breaks down the pros, limitations, and follow-up needs of FIT, Cologuard, CT colonography, and colonoscopy to help you choose the right CRC screening option for your patients. Also learn practical colonoscopy surveillance intervals based on polyp size, number, and pathology.🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery" in your EHR to
#219 Updates in Triglycerides
#219 Updates in Triglycerides Sep 29, 2026 33:31 “The triglycerides are high. Now what?” This episode breaks down a practical approach to elevated TGs, from knowing when to check ApoB or non-HDL-C to choosing lifestyle changes, lipid-lowering medications, and when to suspect an underlying genetic disorder. 🔹Transcript and Show Notes02:17 | Check a non-HDL-C or ApoB if TGs are ≥150 mg/dL 07:18 | Address waist circumference and lifestyle before me
#218 Early-Onset Colon Cancer: 5 Pearls Segment Part 1
#218 Early-Onset Colon Cancer: 5 Pearls Segment Part 1 Sep 23, 2026 15:20 “Too young for colon cancer.” This episode unpacks the red flags of early-onset colorectal cancer (CRC), from blood in the stool and iron deficiency anemia to persistent abdominal pain and changes in bowel habits, and offers practical pearls for closing the clinical loop. Also learn why a “negative” family history may need a yearly refresh.🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery
#217 Treatment for Alcohol Use Disorder: 5 Pearls Segment
#217 Treatment for Alcohol Use Disorder: 5 Pearls Segment Sep 16, 2026 37:37 “It didn’t work.” This episode breaks down practical treatment options (dosing options for naltrexone, acamprosate, topiramate, gabapentin) and counseling pearls to help you meet patients where they are and support their recovery. Also discover blind spots in detox and rehab centers.🔹Transcript and Show Notes🔹 Explore ACP’s Substance Use Disorder Education Hub for videos and an AI-powered patient
#216 Clinician Grief: At the Beside Segment
#216 Clinician Grief: At the Beside Segment Sep 8, 2026 39:59 Have you ever lost a patient and found yourself thinking about them long after the shift ended? This episode explores the grief clinicians can carry after a patient dies, including the losses that aren’t always obvious. We also discuss ways to work through that grief, recognize when it becomes complicated, and lean on your team for support.  🔹Transcript and Shownotes04:12 | What is Clinician Grief
#215 Gallbladder & Biliary Testing: 5 Pearls Segment
#215 Gallbladder & Biliary Testing: 5 Pearls Segment Aug 25, 2026 34:34 How to choose between RUQ ultrasound, CT, HIDA, MRCP, EUS, and ERCP based on the clinical picture? When should you move from diagnostic imaging to therapeutic ERCP, and what should you know about sphincterotomy, stents, and stone removal? Plus, how to interpret bile duct dilation without jumping straight to obstruction?🔹Sponsor: Oakstone CMEUse the code "CORE25" for 25% off: https://www.co
#214 Hyponatremia Management: A Core IM Classic
#214 Hyponatremia Management: A Core IM Classic Aug 12, 2026 44:57 Throwback: Should you really fluid-restrict every patient with SIADH? When can IV fluids make hyponatremia better or worse? Are salt tabs actually doing enough? And what can urine studies tell you before you start treatment? Join us for a practical, physiology-driven approach to hyponatremia management, from fluids and solutes to loop diuretics and identifying the underlying cause. 🔹Sponsor: Searc
#213 Hypertension First-Line Medications Troubleshooting | Bread & Butter Series
#213 Hypertension First-Line Medications Troubleshooting | Bread & Butter Series Jul 28, 2026 32:59 Why can lower-dose combinations be more effective and better tolerated than maximizing one medication? How to troubleshoot common challenges such as amlodipine edema, gout, electrolyte abnormalities, and the patient who says they cannot tolerate anything? Why ACT (ARBs, Calcium Channel Blockers, Thiazides) is the preferred first-line framework, and how to personalize medication choices based on co
#212 Top 10 Highlights of the New Lipid Guidelines
#212 Top 10 Highlights of the New Lipid Guidelines Jul 15, 2026 23:52 Learn from primary care docs what has been practiced and changed from the 2026 ACC/AHA Lipid Guidelines! Learn how the new CPR framework (Calculate, Personalize, Reclassify) and PREVENT risk calculator change statin decisions, why LDL targets are back, and when to use Lp(a), ApoB, and coronary artery calcium (CAC) testing. Discover updated risk-enhancing factors, expanded indications for non-stati

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