Home Podcasts Peptides and Longevity: Redefining Aging and Transforming Health with Dr. Kent Holtorf
Peptides and Longevity: Redefining Aging and Transforming Health with Dr. Kent Holtorf

Peptides and Longevity: Redefining Aging and Transforming Health with Dr. Kent Holtorf

Kent Holtorf, MD 69 Episodes Oct 7, 2026

Dr. Kent Holtorf hosts a show about peptide therapies and their role in longevity, health, and the aging process. Episodes explore the science behind peptides—molecules that regulate immune function, support cellular regeneration, and optimize metabolism—and how they differ from hormones. The podcast examines peptides' potential to reverse chronic illness and improve sleep, brain function, and overall vitality. It is aimed primarily at health practitioners and listeners interested in innovative, integrative approaches to medicine.

Episodes

Why TSH Can Read Normal While Cells Run Low (Part 1 of 3)
Why TSH Can Read Normal While Cells Run Low (Part 1 of 3) Oct 7, 2026 00:47:20 Most of what we were taught about reading a thyroid panel assumes a young, healthy patient with no stress, no toxin exposure, and no chronic illness. I have yet to meet that patient in practice. This lecture is the first of three I recorded for practitioners, and it lays the groundwork for everything I teach about thyroid, peptides, and bioregulators.I start with the immune system because, in my e
When The Thyroid Labs Look Fine And The Patient Is Not
When The Thyroid Labs Look Fine And The Patient Is Not Sep 23, 2026 00:44:42 Most of the patients I see have already been told their thyroid is fine. A TSH in range, a free T4 in range, and a conversation that stops there. My argument in this session is that in chronic illness those two numbers are the least informative part of the panel, because they tell you about signalling and circulating supply rather than about what is getting into the cell and being used.So I go thr
Unlock the Secrets to Longevity and Chronic Illness With 3rd Generation Oral Peptides
Unlock the Secrets to Longevity and Chronic Illness With 3rd Generation Oral Peptides Sep 9, 2026 00:56:27 I keep coming back to one idea in this talk: the immune system is not a side character in aging and chronic illness—it is closer to the director. I lay out the teeter-totter first: the TH1 and regulatory side against the TH2 and TH17 side, and how the thymus winding down from childhood on quietly shifts that balance until an aged immune phenotype takes over. From there, the dominoes are familiar t
Breakthroughs in Longevity Science and Aesthetics from the Inside Out with Oral Peptide Bioregulators
Breakthroughs in Longevity Science and Aesthetics from the Inside Out with Oral Peptide Bioregulators Aug 26, 2026 00:40:06 I did not plan to give this talk. I arrived at the AIMS Symposium, realized how much of the room was aesthetics, and did not have a single slide on the oral skin bioregulators we have been working on for years. So I rebuilt it. What is happening in that room is worth paying attention to, because beauty and functional medicine are being pushed together and nobody has decided yet whether the plastic
A Multi System Treatment Approach to Traumatic Brain Injury, PTSD & Neurodegenerative Disease Using Peptides
A Multi System Treatment Approach to Traumatic Brain Injury, PTSD & Neurodegenerative Disease Using Peptides Aug 13, 2026 00:43:15 A head injury does not stay in the head. In this episode of Peptides and Longevity, I share the talk I gave for Boston BioLife on treating traumatic brain injury, post-traumatic stress, and neurodegenerative disease as one connected problem instead of three separate ones. I walk through why the blood-brain barrier and the gut open at the same moment, how the immune system shifts and pulls mitochon
The Hidden Reason Your Immune System Ages Faster 
The Hidden Reason Your Immune System Ages Faster  May 13, 2026 00:46:08 Aging may begin in the immune system long before symptoms appear. In this Peptides and Longevity episode, Dr. Kent Holtorf breaks down the science behind peptides, immune balance, inflammation, mitochondrial health, sleep, brain function, and why peptide therapies are being explored as tools to support healing and healthy aging. - - - - - Kent Holtorf, MD, is the founder and medical director of Ho
The 5-Day Reset That Calms Cravings
The 5-Day Reset That Calms Cravings Apr 29, 2026 00:39:35 Fasting isn’t just willpower, it’s a cellular switch. In this Peptides and Longevity episode, nutrition professional Renee Fitton breaks down how fasting mimicking supports deep cellular cleanup, metabolic markers, cravings, and longevity pathways—without the struggle of a traditional water fast.- - - - - Renee Fitton, MS, RD is a longevity-focused registered dietitian and Director of Education fo
Peptides, Faith, and the Truth About Weight Loss
Peptides, Faith, and the Truth About Weight Loss Apr 15, 2026 00:47:51 What if weight loss isn’t about willpower, but restoring what your body lost along the way? In this episode of Peptides and Longevity, Dave Knapp shares his journey through obesity, type 2 diabetes, GLP-1 therapy, sobriety, and faith, revealing how peptides, lifestyle change, and spiritual surrender reshaped his health and purpose.- - - - - Dave Knapp is a podcaster and founder of On The Pen, an o
Why Great Pharmacists Still Struggle to Stay Open
Why Great Pharmacists Still Struggle to Stay Open Apr 1, 2026 00:31:12 Independent pharmacies are filling prescriptions at a loss, and most people have no idea. In this episode of the Peptides and Longevity Podcast, Dr. Lisa Faast breaks down why margins are getting crushed, what clinicians miss about business, and how pharmacy owners can build real stability without losing the heart of patient care.- - - - - Dr. Lisa Faast, PharmD is a pharmacist with over two decad
Practicing Medicine Freely Through the PMA Model
Practicing Medicine Freely Through the PMA Model Mar 18, 2026 00:25:50 What if healthcare practitioners could serve people more freely while preserving patient choice? In this episode of Peptides and Longevity, Michael Blake, founder of Forgotten Formula, explains Private Membership Associations (PMAs), how member-based models function, and why some clinicians are exploring constitutional frameworks to support integrative, root-cause care.- - - - - Michael Blake is t
You Can’t Treat What You Don’t Test
You Can’t Treat What You Don’t Test Mar 11, 2026 00:31:00 Healing often stalls when care relies on guesswork instead of clarity. In this episode of Peptides and Longevity, Debi Bryk of MaxGen Labs explains how genetic testing provides a lifelong blueprint for personalized nutrition, lifestyle, and supplementation, helping practitioners and individuals move from trial and error to targeted healing.- - - - - Debi Bryk, NC, BCHN, is a board-certified holist
He Was Preparing to Lose His Bladder. Then Something Changed.
He Was Preparing to Lose His Bladder. Then Something Changed. Mar 4, 2026 00:41:06 He was preparing to lose his bladder after a cancer diagnosis… until his second surgery revealed something no one expected. In this episode of Peptides and Longevity, Jon Vengochea shares how personalized, multi-system care alongside conventional treatment transformed his strength, outlook, and recovery journey.- - - - - Jon Vengochea is a patient at Holtorf Medical Group who shares his personal e

Recommended