Siim Land Podcast
Siim Land is an author, speaker, and consultant. He talks about optimizing health, performance, and longevity with different techniques and biohacking.
Episodes
#508 I Researched 100+ Supplements - Here's My Breakdown
Get The New Science of Supplements book: https://amzn.to/4ebe2LwTimestamps:00:00 Intro00:30 Top evidence-based supplements29:55 Supplements with the worst evidence34:25 Supplements that need more research47:58 Conclusion100 Supplements Ranked Tierlist Worst to Best: https://youtu.be/W8DZbYyuDmAStart rewinding your biological clock: https://www.siimland.co/courseP.S. This is not professional medica
#507 Siim Land: Most Important Longevity Biomarkers - Chris MM Health Podcast
This is a replay of Siim Land on Chris MM Health's YouTube channel: https://www.youtube.com/watch?v=vXpES7lty2Q Timestamps: 0:00 – Intro0:56 – Beating Bryan Johnson In Biomarkers4:00 – Longevity Escape Velocity Explained4:39 – Can Humans Live To 150+ Years?10:10 – Biological Age & Longevity World Cup12:34 – Biological Age Of 10 Years Old?!14:10 – Most Important Longevity Biomarkers16:35 –
#506 Stanford Scientist: Why Aging Accelerates at 44 and 60 - Dr. Michael Snyder
Dr. Michael Snyder is a genomicist, professor, and former chair of genetics at Stanford University School of Medicine. He is the Director of the Center for Genomics and Personalized Medicine at Stanford University and a pioneer in precision medicine and multi-omic profiling.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:2
#505 Siim Land: How I Ranked #1 in the Longevity World Cup and Lowered Biological Age by 21.1 Years
Siim Land returns as the current leader of the Longevity World Cup, to break down supplements, biomarkers, VO2 max, inflammation, sleep, and the difference between building health versus simply maintaining it.Watch on YouTube: https://www.youtube.com/watch?v=ogy7l0nka-Y
#504 How to Keep Your Skin Young Without Expensive Treatments - Dr. Alexis Ortega
Dr. Alexis Ortega is board-certified in longevity, regenerative and aesthetic medicine. He has a clinic Ad Astra in Barcelona, Spain.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:55 How to counteract age-related loss of facial harmony aside from just wrinkles12:30 Does growth hormone change the face18:10 Bon Charge spons
#503 Scientists Analyzed 400 Drugs — Only 14 Were Linked to Longer Life - Dr. Kevin Perez
Dr. Kevin Perez is a computational biologist working at the cutting edge of aging science and drug discovery. His work focuses on aging research, drug repurposing, and integrating complex multi-omics data to better understand how we can extend healthspan.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:47 Kevin’s study abou
#502 What the Most Promising Longevity Drug Did for Humans - Dr. Brad Stanfield
Join our LONGEVITY Community: https://www.skool.com/longevity-societyTimestamps:00:00 Intro00:37 Why Brad crowd funded a rapamycin trial03:22 What Brad’s rapamycin trial found12:57 Why rapamycin blunted the effects17:17 Rapamycin effects on grip strength19:57 Rapamycin and immune effects21:47 Effects on biomarkers25:22 Brad’s thoughts on rapamycin moving forward31:52 Metformin exercise effects32:5
#501 Sleep, Circadian Rhythm & What Actually Works (Q&A with Dr. Greg Potter)
Dr. Greg Potter has a PhD from the University of Leeds in sleep, nutrition, and metabolism. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:45 Catchup02:05 Are circadian rhythms nature or nurture09:55 What’s ideal timing of sunlight exposure for circadian anchoring15:25 Bon Charge sponsorship 20:30 Does creatine increase D
#500 After 25 Years of Brain Scans, Here’s What Separates High Performers - Dr. Andrew Hill
Dr. Andrew Hill has a PhD in Cognitive Neuroscience from UCLA and has extensive experience in the field of neurofeedback and QEEG. He founded the Peak Brain Institute. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:45 — Andrew's new book Gifted and Tortured04:47 — Diagnosis vs resource-based brain optimization06:20 —
#499 Humans Aren’t Supposed to Live This Long (Grandmothers Might Explain Why) - Dr Kristen Hawkes
Professor Kristen Hawkes is a pioneering anthropologist whose work helped bring the grandmother hypothesis to the spotlight of human evolution research. Through fieldwork and evolutionary theory, she argued that older women may have played a crucial role in shaping the human life course, not just by living longer, but by helping feed and support grandchildren. That idea helped reframe menopause, l
#498 Lifestyle Adds 5 Years To Your Life, But This Determines the Rest (Physicist Explains) - Dr Uri Alon
Dr. Uri Alon is a physicist-turned-biologist, a professor at the Weizmann Institute, and one of the leading thinkers exploring how complex biological systems work. In this episode, we discuss his research on the effects of genetics, lifestyle, environment, and luck on human lifespan.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00
#497 The Complete Longevity Ranking: Lifestyle, Medicine, Biohacking
Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro00:36 Lifestyle bracket06:50 Lifestyle bracket winners11:47 Join my online community18:46 Medicine / pharmaceutical bracket19:20 Medicine /pharmaceutical bracket winners22:32 Geroscience bracket33:13 Geroscience winners35:00 Biohacking bracket40:16 Biohacking bracket winners43:04 F
#496 95-Year-Old Scientist Reveals the Nutrient Behind Human Brain Evolution - Dr Michael Crawford
Professor Michael Crawford is a renowned scientist and Director of the Institue of Brain Chemistry and Human Nutrition in Imperial College London. He’s known for his research demonstrating the essential role of omega-3s specifically DHA in brain development and human evolution. He’s been pioneering this research since the 70s and he’s 95 years old himself.Check out Bon Charge wellness products (Co
#495 Inside the Search for a 300% Lifespan Breakthrough - Dr Ben Blue
Dr. Benjamin Blue is the Chief Executive Officer of Ora Biomedical, where he leads the company’s mission to develop therapies that target the biology of aging to prevent and treat disease. Dr. Blue holds a Ph.D. in Molecular Medicine and Mechanism of Disease (M3D) from the University of Washington School of Medicine and a B.S. in Biochemistry from the University of Oregon.Timestamps:00:00 Intro00:
#494 Longevity Experts Discuss Bloodwork - Panel with Dr. Brad Stanfield, Dr. Matt Kaeberlein, and Dr. Michael Lustgarten
Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro00:41 Experts framework for bloodwork03:41 What can bloodwork tell you about your health and what not18:21 Brad’s top 3 most useful biomarkers20:21 Matt’s top 3 most useful biomarkers21:11 Is testosterone testing worth it on the population level29:01 Michael’s top 3 most useful bio
#493 - 100 Exercises Ranked for Maximum Healthspan
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:20 Zone 2 cardio01:20 Barbell back squat01:38 Pistol squats02:21 Split squats02:58 Deadlift03:26 Pullups04:40 Pushups05:44 Barbell row07:35 Dumbbell row07:42 Overhead press08:29 Dumbbell shoulder press09:01 HIIT09:35 Delt flies11:30 Incline bench press12:21 Decline bench pres
#492 I Read All the Human Studies on the Most Popular Peptides - Here's What the Data Shows
Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro01:15 TB405:02 Thymosin alpha 109:44 Join our longevity community10:43 Epitalon15:26 MOTS-c19:30 Humanin21:32 Cerebrolysin23:49 Semax24:40 CJC1295 (Ipamorelin)26:31 MK677 (Ibutamoren)28:26 Tesamorelin29:12 IGF-1 LR329:45 Copper GHK32:22 Retatrutide33:55 Melanotan 235:30 Final overv
#491 Glycine and Cancer Risk, The Health Priorities That Actually Matter, and More - Q&A
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Top Health Factors and Biomarkers That Matter the Most17:44 Bon Charge sponsorship18:50 Glycine and cancer risk22:05 Can supplements improve IQ and cognition25:19 Best autophagy routines31:24 Thoughts on young plasma exchange35:26 Injectible NAD and glutathione38:05 Too high cortisol
#490 How to Get Fitter As You Age - Dr Elie Abirached
Dr. Elie Abirached is a Harvard alumnus, and founder of Restore. He is the creator of the Limitless Human methodology, a science driven framework designed to reduce biological age, enhance resilience, and optimise long term health.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:16 How Elie got into fitness and wellness07:0
#489 Inside the Dog Aging Project: What It’s Teaching Us About Longevity - Dr Daniel Promislow
Dr. Daniel Promislow, DPhil, is a Senior Scientist and Scientific Advisor at the HNRCA. He has worked for over 30 years on the biology of aging and has published over 180 papers. Currently, he's working on the Dog Aging ProjectCheck out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:26 What is the Dog Aging Project02:26 Size an
#488 Health Testing Panel with Dave Pascoe, Dr Joy Kong, Inka land and Adam Ficsor
Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro00:00 Panel members introduction05:20 Recap of our week at AIWO18:30 Blood marker testing20:40 Longevity World Cup competition30:00 DEXA scan36:35 Physiotherapy and posture analysis37:55 Skin anti-aging treatments41:55 Exosomes and stem cells for skin anti-aging49:20 Unique tests w
#487 The Future of Longevity: What Comes After Diet & Exercise - Panel Discussion at Copenhagen Health Week 2025
Timestamps:00:00 Why does longevity matter03:25 Tracking for preventing chronic diseases06:14 Advanced longevity therapies we’re excited about10:30 How long would you like to live14:25 Will longevity technology become available to everyone17:27 Big moonshots in longevity23:32 What does the life of a 70 year old look like in 204026:32 Most important step towards your longevity you should take today
#486 My 2026 Longevity Routine (Full Breakdown)
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:44 My results in 202506:19 Body composition goals16:00 Bon Charge sponsorship16:52 My 2025 fitness results25:05 My 2026 fitness goals30:25 My workout plan for 202635:05 My nutrition plan for 202643:27 My supplement protocol for 202646:37 My sleep routine and goals48:47 My blo
#485 The Ultimate Health Superpodcast (Best Clips of 2025)
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:15 100 supplements ranked from worst to best57:00 Bon Charge sponsorship57:55 How to eliminate microplastics and heavy metals from your body feat Dr Anil Bajnath01:27:20 Nutrition masterclass with Physionic and Dr Greg Potter02:27:25 Exercise masterclass with Physionic and Dr
#484 The Ultimate Health Tierlist - 100 Health Habits Ranked from Worst to Best
Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro00:15 Zone 2 cardio01:44 Napping03:03 Walking05:09 Polyphasic sleeping06:47 Mouth breathing07:52 Soleus pushups09:40 Stretching11:10 Mobility12:03 Yoga13:20 HIIT14:20 Sprinting14:48 Plyometrics16:12 Morning sunlight17:05 Evening sunset17:52 Blocking out blue light19:12 Red light th
#483 Q&A Training fast twitch muscle fibers instead of lifting weights, How much protein for longevity, My all out supplement stack
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 What level of sports performance is unhealthy04:15 How much protein is bad for aging and longevity11:45 Bon Charge sponsorship12:45 Do I want to reach the longevity escape velocity16:40 Absorbing supplements through the skin18:40 Optimal level of testosterone for longevity22:50 Shoul
#482 Why Scientists Believe Lithium May Be a Longevity Molecule
Jon Berner, MD PhD is a board certified Psychiatrist from Seattle with 27 years of experience. He's also published several scientific papers.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:20 Why Dr Berner became interested in lithium04:50 Lithium’s benefits in Alzheimer’s and dementia10:50 Lithium’s effects on mTOR an
#481 The Anti-Aging Pill Chinese Scientists Are Developing - Aiming for 120+ Lifespans - Yip Tszho
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandYip (Zico) Tszho is the Chief Executive of Lonvi Biosciences, a longevity-drug start-up, in Shenzhen, China. They're developing pharmaceuticals for extending human lifespan. We discuss their first senolytic called PCC1. Timestamps:00:00 Intro00:15 Articles about a pill making people live to 15002
#480 The Science of Saunas: How Heat Boosts Fitness & Longevity - Brady Holmer MSc
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandBrady Holmer is a science writer and researcher with a Master's degree in Human Performance from the University of FloridaTimestamps:00:00 Intro00:40 Why heat acclimation has performance benefits08:10 How to train heat acclimation12:40 Bon Charge sponsorship13:30 Benefits of the sauna for fitness
#479 Longevity Testing 101: What Really Matters (with Siim Land and Dr. Joy Kong)
Join our upcoming retreat in January 2026: https://www.siimland.co/retreat Timestamps:Introduction (00:00)Discussion on longevity clinics and testing (01:52)Essential health tests and biomarkers (05:45)Improving VO2 Max and cardiovascular health (11:28)Blood tests and metabolic health (16:42)Hormone tests and longevity (21:35)Microbiome tests and toxicity (26:55)Microplastics and environmental tox
#478 Mitochondria Scientist: The Only Proven Way to Extend Human Lifespan - Dr Mark Tarnopolsky
Dr. Mark Tarnopolsky is a Professor and Division Head of Neuromuscular and Neurometabolic Disorders in the Department of Pediatrics at McMaster University. He completed a PhD in Cell Biology and Metabolism in 2001.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:25 What are mitochondria03:55 Mitochondria in aging and longev
#477 The Science of Longevity Genes: What We’ve Learned from Centenarians - Dr Tyler Panzner
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:48 The genetics of a 117-year-old woman08:16 Resilience, immunity and longevity14:33 Muscle building genetics19:33 FOXO3 and stress resilience24:53 FOXO3 gene editing32:08 Can telomere lengthening be harmful to some individuals38:58 IGF-1 and growth hormone and longevity50:08
#476 Siim Land on Human Immortality, Gene Editing, Biomarkers - The Beyond Tomorrow Podcast
Timestamps0:00 – Introduction4:12 – Humans adapt, and that changes the rules9:58 – Diet diversity, sensitivities, and n of 116:51 – Assess first: biomarkers that predict disease risk18:27 – Fixing sleep, movement, diet, environment22:47 – Caution on rapamycin, metformin, methylene blue25:54 – FOXO3 stem-cell study and what it means37:15 – Mindset and willpower as real enhancers41:44 – TMG, astaxan
#475 Q&A: Biggest things that contribute to my health, does caffeine age the brain, can you make up for lost sleep and more
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Does exercise increase inflammation03:03 Melatonin megadosing research04:23 NOVOS vs Blueprint VS DoNotAge07:44 Hidden things that contribute to my health12:14 Bon Charge sponsorship13:05 How to improve night shift work15:40 Supplements to take before the sauna17:15 Does caffeine age
#474 Longevity Supplements Ranked From Best to Worst
Get my 2025 supplement guide: https://www.siimland.co/supplement-list-2025Timestamps:00:00 Intro00:14 Taurine01:19 Apigenin01:55 Resveratrol03:20 Rapamycin04:55 Metformin06:11 Calcium AKG07:30 Melatonin08:16 SIRT609:05 NAC09:43 NMN, NR, Niacinamide11:10 Niacin13:58 Glycine15:16 Spermidine16:44 Omega-3s17:40 Creatine18:48 Pterostilbene19:19 Magnesium20:16 Vitamin K220:45 Sulforaphane21:34 Curcumin2
#473 Tech Expert: Why Life Speeds Up As You Age (And How To Slow It Down!)
Chris Dancy is called 'the most connected man on Earth' because of his pioneering use of technology in everyday life and health optimization.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:23 Why Chris is the most connected man on earth03:38 How Chris used technology to lose weight and get healthy08:43 How technolo
#472 Scientist Reveals the Hidden Program of Aging and How to Control It - Josh Mitteldorf PhD
Josh Witteldorf is a PhD in physics who pivoted to researching aging and investigated the evolutionary reasons for aging and human lifespan. He's written the book Cracking the Aging Code.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:30 How Josh, as a physicist, got into aging research04:35 Why aging is an evolutionar
#471 Ranking 100 Health Biomarkers (Most to Least Important)
Get my free bloodwork cheat sheet: https://www.siimland.co/bloodwork-cheat-sheetTimestamps:00:00 Intro00:32 Resting heart rate02:27 hsCRP03:32 VLDL03:52 LDL particle count04:31 Homocysteine 05:26 Respiratory rate06:30 VO2 max07:36 Body fat percentage09:18 BMI11:57 HRV14:14 Waist circumference and waist to hip ratio16:00 Visceral fat mass and liver fat18:42 White blood cells20:35 Albumin21:11 Muscl
#470 The New Science Linking Your Body Clock to Longevity - Greg Potter PhD
Greg Potter, PhD, is a circadian rhythm and time-restricted eating expert who researches sleep, circadian rhythms, and time-restricted eatingCheck out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro01:05 Circadian clock dysfunction and hallmarks of aging10:35 How the circadian clocks affect aging and lifespan17:00 Bon Charge sponsorsh
#469 Latest Research About Reversing Aging Cells - Dr Paul Robbins, PhD
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:22 Dr Robbins background in longevity research01:57 What is cell senescence07:52 Benefits of senescent cells early in life09:07 Does eliminating senescent cells increase lifespan14:50 How to eliminate senescent cells17:35 Most researched senolytics22:15 Can you reverse the ag
#468 Nutrition for a Longer Life: 2 PhDs Explain What Works
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:20 Greg and Siim's background06:35 Our opinion on what’s the best diet12:50 What is most important: how much you eat, what you eat, when you eat18:15 Bon Charge sponsorship19:05 How important is the timing of when you eat42:30 Best diet for top 1% longevity, top 1% athlet
#467 I Analyzed Bryan Johnson's Biomarkers and The Results Are...
Get your free personalized health review: https://www.siimland.co/reviewTimestamps:00:00 Intro01:10 Summary of our biomarker differences02:30 Fitness markers09:45 Body composition markers14:45 Inflammation and immune markers19:30 Metabolic health markers24:15 Cardiovascular markers36:30 Kidney markers43:45 Liver markers47:00 Hormone markers53:20 Experimental longevity tests56:45 PhenoAge biologica
#466 Ultimate Supplement Tier List 2025 - 100 Supplements Ranked Worst to Best
Get my 2025 supplement guide: https://www.siimland.co/supplement-list-2025Timestamps:00:00 Intro00:16 Ca-AKG01:00 NAD Boosters02:54 Senolytics03:53 Glycine and trimethylglycine04:54 Glucosamine sulfate05:25 Taurine05:48 MSM and chondroitin sulfate06:18 Turmeric06:50 Ashwagandha07:52 Citrulline08:02 Thiamine08:40 Chromium09:14 Melatonin09:44 Theanine10:00 Rhodiola rosea10:24 Vitamin C11:01 Methylat
#465 Science-Backed Ways to Lower Cancer Risk (with a Cancer Biologist) - Dr Joe Zundell
Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro01:10 New research in cancer04:35 Circadian rhythms and chemotherapy07:55 Does living close to golf courts increase Parkinson’s and cancer risk11:35 Does glyphosate increase cancer risk13:40 Do you need to worry about cancer if you’re young17:20 Why cancer rates are rising in young
#464 Exercise Roundtable with Dr Greg Potter and Dr Nicolas Verhoeven (Physionic)
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:35 Why exercise and physical activity matters05:05 What exercises does to your health12:15 Bon Charge Sponsorship13:05 Dangers of sedentary behavior14:00 Why exercise improves health20:25 Why you need to build a reserve23:35 Physionic’s current workout routine27:25 Greg’s cur
#463 The Science of Detox with Dr. Anil Bajnath
Get Bon Charge (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:35 Is Detox a Scam05:20 How the body detoxifies itself16:18 Bon Charge sponsorship17:10 How to support daily detoxification pathways30:45 Mineral waters and mineral baths37:10 Do binders like clay and charcoal work41:10 Are there supplements that support detox45:55 Therapeutic detox therapies47:45 Fix your gut befor
#462 Cardio Faceoff: HIIT vs Zone 2 - Which One Is Superior with Exercise Scientist Kristi Storoschuk
Get Bon Charge (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:18 Kristi’s new study on zone 2 cardio07:33 Does zone 2 provide unique mitochondrial benefits12:58 VO2 max15:18 Bon Charge sponsorship16:08 Why athletes do so much zone 2 training20:43 How much volume of exercise you need for mitochondrial adaptations25:43 Is zone 2 better than HIIT over a longer time period?32:38 H
#461 Top Longevity Supplements Analyzed by PhD Experts - Dr Greg Potter and Dr Nicolas Verhoeven
Roundtable discussion with Dr. Greg Potter ( @gregpotterphd ) and Dr Nicolas Verhoeve ( @Physionic )Timestamps:00:00 Intro00:28 What supplements and/or pharmaceuticals we would give people05:58 Underrated longevity supplements08:35 Underrated medications13:40 The stupidest things we've done for health24:00 Omega-3 fatty acids (fish oil, algal oil) and longevity26:20 Vitamin D and longevity29:4
#460 50 Minutes of Uncomfortable Truths About Fat Loss & Health No One Tells You
Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro00:58 How I started writing books04:28 Main keys of fat loss diets09:48 Supplements for fat loss10:33 Effects of diet sodas on fat loss13:48 Metformin effects on longevity17:38 How to optimize sleep23:33 Melatonin supplementation26:30 Calories and energy balance shortcomings30:15 E
#459 Q&A: Collagen vs Glycine, How Much Alcohol is Healthy, How to Improve Kidneys, and Much More
Get Bon Charge (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Can you get benefits of collagen with high dose glycine?02:53 High blood sugar levels and inflammation05:03 Why I eat kiwis before bed05:48 How much alcohol is healthy09:15 Can creatine and glycine increase kidney size10:33 Can a daily sauna be too much13:33 Bon Charge sponsorship14:24 Middle path between a perfect routine
#458 The Forgotten Role of Creatine and Exercise in Depression - Nicholas Fabiano, MD
Get Bon Charge (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:45 Creatine and depression benefits07:15 Creatine and inflammation08:20 Traumatic brain injury10:53 Bon Charge sponsorship11:45 Creatine and anxiety13:35 Dietary creatine and depression15:00 Exercise and depression16:35 Why exercise improves depression21:00 Depression analogue to diabetes27:25 Why some people get de
#457 Top Oral Peptides for Tissue Regeneration and Healing
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Timestamps:00:00 Intro00:35 Peptide regulations in Australia and USA06:35 Peptides for repair and recovery10:35 Why Kyal got into peptides12:55 Oral peptides vs injectable ones19:35 BPC gut repair effects25:35 BPC joint effects27:10 The Wolverine stack for joints32:55 Brain peptides42:35 Creatine45:20 Epitalon48:05 Longevity therapeutics50:40
#456 Q&A at Vitalist Bay About Health and Longevity
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Timestamps:00:00 Intro00:18 How long do I want to live01:04 What improved my health the most02:46 Do I have a doctor04:15 Figuring out what's true about health09:18 What people get wrong about creatinine10:35 My predictions for longevity in the next 5-20 years12:38 How much do we spend on health tests a year14:25 What we track most frequen
#455 The Optimal Plan to Build Muscle & Lose Fat - Menno Henselmans
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Timestamps:00:00 Intro00:16 Surprising new research about muscle growth03:16 Surprising new research about diets08:16 How you need to train to build muscle18:26 Can you build muscle sprinting20:16 Compound lifts vs machines21:26 Do growth hormone and testosterone increase muscle24:26 Functional movements vs machines27:06 Training frequency30:4
#454 25 Minutes to Make You Healthier Than 95% of People
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Join the next conference in Tallinn, Estonia: https://www.hololifesummit.com/Timestamps:00:00 Longevity Intelligence02:30 Lifestyle risk factors08:19 Longevity Horizon11:13 Genetic risk factors15:55 Biomarkers22:19 SummaryMy evidence based longevity routine: https://youtu.be/4xkRcfeGDoo
#453 Nitric Oxide: The Molecule for Better Blood Flow and Longevity
Get Bon Charge Infrared Sauna Blanket (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:23 Why is nitric oxide important04:08 Nitric oxide, blood pressure and erectile dysfunction10:58 Bon Charge sponsorship11:48 How to increase nitric oxide13:53 Effects of microbiome on nitric oxide21:53 Exercise and breathing26:53 Sauna29:30 Supplements that increase nitric oxide36:33 Restart y
#452 Dr Eye Health Explains How to Preserve Your Eyesight with Age
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Timestamps:00:00 Intro00:25 Why eye health is important02:50 Link between poor eyesight and chronic diseases05:25 Are digital screens bad for the eyes09:10 Exercises for the eyes17:55 Red light for eye health26:35 Effects of sunlight on eyes30:05 Sunglasses33:20 Nutrition and supplements46:40 Diabetes and eye health53:00 Glasses and contact le
#451 Creatine Masterclass: Benefits, Myths, Dosage and Loading with Dr Darren Candow
Get Bon Charge products (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:25 Why is creatine the most studied supplement of all time01:45 What does creatine do to your body05:45 Why supplement creatine07:30 Typical creatine dosages09:35 Creatine and sleep deprivation11:45 Bon Charge sponsorship12:36 Creatine and muscle growth16:16 How and when to take creatine18:51 Creatine and s
#450 Optimize Fertility and Health in a Modern Toxic World - Kayla Barnes-Lentz
Get Bon Charge Infrared Sauna Blanket (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:35 How Kayla interviewed his date for his health04:35 Why Kayla got interested in health09:11 Bon Charge sponsorship09:57 Male vs female longevity19:17 How Kayla is preparing her body for getting a baby29:37 How to support fertility32:17 How many kids is optimal34:17 Protocol for removing toxi
#449 Matt Kaeberlein Unleashed: Rapamycin, Peptides, Protein, Supplements Q&A
Timestamps:00:00 Intro00:37 Thoughts on Bryan Johnson stopping rapamycin06:59 Are more antioxidants always better09:57 Supplements versus lifestyle for longevity12:43 Life extension compounds other than rapamycin17:00 Matt’s controversial takes on supplements and lifestyle28:30 My book promo28:55 Matt’s thoughts on peptides for longevity34:35 Thymus rejuvenation protocol44:55 NAD IVs and Therapeut
#448 Julie Gibson Clark Sharing Her Longevity Routine to Stay Healthy In Her 50s
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Timestamps:00:00 Intro01:07 Julie’sreaction to the news articles about her04:12 How Juliegot interested in health11:52 My bookpromo12:14 Julie’s2025 diet routine20:47 Fastingmimicking diet26:02 Julie’sexercise routine28:42 Bonedensity and menopause33:22 Supplements40:22 What doesJulie’s family thinks about health46:32 Sleep53:22 BloodworkJulie
#447 How to Reduce Liver Fat and Improve Your Liver Health - Andy de Santis RD, MPH
Get Bon Charge Infrared Sauna Blanket (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:50 Why is the liver such an amazing organ04:05 Consequences of liver fat accumulation07:05 Can you reverse liver damage and liver fat09:50 Visceral fat vs liver fat11:20 Bon Charge sponsorship12:05 Key determinants of liver fat14:45 Do you need to lose weight to lose liver fat16:10 Diet for lo
#446 Q&A Megadosing Astaxanthin, Fixing Food Sensitivities, and More with Tim Gray
Join the Health Optimisation Summit (Code SIIM for discount): https://usa.healthoptimisation.com/?promo=SIIMTimestamps:00:00 Intro01:30 How to get sleep when your mind is racing06:45 Thoughts on agmantine sulfate08:25 Food sensitivities and autoimmunity14:20 Is NMN safe long-term18:20 Is CoQ10 worth it?24:30 Omega-3 supplements and biological age26:40 Optimal astaxanthin dosage29:20 How to increas
#445 Longevity Supplements Ranked by Doctor Sandra Kaufmann
Get Bon Charge red light therapy for 15% off: https://boncharge.com/pages/siimlandTimestamps:00:23 Dr Sandra’s 7 Tenets of Aging03:20 Rating system for supplements05:00 Astaxanthin07:50 NAD boosters11:15 Bon Charge Ad12:05 Glycine15:30 Curcumin18:50 Ginger and GLP122:25 Melatonin24:30 Carnosine30:15 AKG35:20 Taurine39:05 Disappointing supplements39:50 Resveratrol43:40 Multivitamin46:10 Dihydromyri
#444 The Best Bloodwork for Longevity - Dr Michael Lustgarten
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Timestamps:00:16 Philosophy for bloodwork and longevity09:36 Most important bloodmarkers to measure14:20 Bloodmarkers for heart disease and metabolic disease21:20 Is low cholesterol bad31:00 Malnutrition and cachexia40:40 Biological age clocks43:55 Standardized protocol before taking bloodwork52:50 Heavy metals56:25 Bloodwork for unlimited bud
#443 Physionic on Longevity, Autophagy, Supplements, and More
Get Bon Charge red light therapy for 15% off: https://boncharge.com/pages/siimlandTimestamps: 00:38 Nick’s PhD and autophagy research 02:33 What is autophagy 03:53 Autophagy and longevity 08:05 Bon Charge Sponsorship 08:55 Where autophagy comes from 11:40 What triggers autophagy 18:15 mTOR and longevity 20:15 Should you eat a lower protein diet 25:45 Supplements for autophagy 28:35 Metfor
#442 Regenerative Doctor on How to Fix Joint Pain Without Surgery - Dr David Karli
BioPrime oral BPC157 with code SIIM10 for 10% discount - Get 3 month supply for best effects: https://www.bioprimesupplements.com/index.php?route=product%2Fproduct&product_id=53&tracking=g8PrbVPWwr3K1a42mbbnslSqmty6fFgjT3YxDU0MAXwf18eL4MBMHgSQgFBSv3FrTimestamps:00:25 Dr Karli’s training in cell therapies07:00 BioPrime Supplements Sponsorship07:55 Why do people develop pain disorders10:00 I
#441 How to Balance Your Nervous System for Optimal Health - Dr Mark Atkinson
Get Bon Charge red light therapy for 15% off: https://boncharge.com/pages/siimlandTimestamps: 00:41 Mark’s backstory 05:41 How the body and mind connected 11:40 How to balance your nervous system 20:30 How to stimulate the vagus nerve 23:10 Nutrition and gut health 27:10 Blood markers for stress 30:00 You need to focus on both mental and physical health 40:20 How to deal with health anxiety
#440 GENETICS Based Supplements You Should AVOID - Dr Tyler Panzner
Timestamps: 00:00 Introduction 01:40 How Tyler Got Into Genetics 07:00 How Genes Affect Caffeine Metabolism 14:35 Creatine and Genetics 22:40 Citrulline and Arginine 27:35 Glycine 32:35 Histamine, Fermented Foods, Bone Broth 37:20 Food Sensitivities and Plant Chemicals 41:00 Methylation 44:05 Microplastics 48:40 Melatonin 54:30 Vitamin D 59:55 Omega-3s 01:04:40 Where to Start Understan
#439 How Stress Resilience Makes You Live Longer - Dr Olli Sovijärvi
Get Olli's and My Longevity Books (Code SIIMLAND for a 15% discount): https://biohackercenter.com/collections/books-longevity-biohackingTimestamps:00:18 Overlap Between Resilience and Longevity09:48 Hormesis and Adaptation14:48 Voluntarily Exposing Yourself to Stress20:18 Sauna Benefits32:43 Contrast Therapy with Sauna and Cold34:08 Benefits of Cold Exposure43:23 How to Track Your Response to
#437 The Ambitious 3 Step Plan to Solving Aging and Death - Nathan Cheng
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
Timestamps:
00:00 Intro
00:21 Why Nathan Dropped Out of His PhD Thesis to Pursue Longevity Research
07:51 Roadmap to Extending Human Lifespan
12:41 Body Replacement
18:33 Organ Cloning
26:11 Brain Replacement
33:36 Cyborg Organs
36:38 Pausing Aging in the Body
45:58 Bioengineering and Gene Therapy
56:36 Vitalism
Nathan Cheng X
#438 Skin Anti-Aging Masterclass with Dr Alexis Ortega
Get Bon Charge infrared sauna blanket 15% off: https://boncharge.com/pages/siimland
Timestamps:
00:00 Intro
00:30 Why Skin Anti-Aging Matters
02:15 What Everyone Should Do for Skin Anti-Aging
06:25 Bon Charge Sponsorship
07:12 Skin Aging Analysis Techniques
12:15 Pores and Cleaning the Skin
15:25 Three Basic Products Alexis Gives His Patients
20:55 Best Sunscreens to Take
37:30 Re
#436 Is Methylene Blue the Magic Bullet for Health? - Dr Scott Sherr
Get Bon Charge infrared sauna blanket 15% off: https://boncharge.com/pages/siimland
Timestamps:
00:00 Introduction
00:30 What Is Methylene Blue
05:35 Methylene Blue Antiviral Effects
12:55 Methylene Blue Effects on Mitochondrial Function
17:55 Is Methylene Blue and Oxygen
24:30 Methylene Blue for Exercise
26:10 Nitric Oxide
31:25 Does Methylene Blue Have Longevity Benefits
39:50 S
#435 Hormone Doc Amy Killen Reveals the TRUTH About TRT and HRT Safety
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
Timestamps:
00:30 Is Hormone Replacement Therapy Good or Bad for You
05:22 Benefits of Treating Aging Hormones
08:20 Cardioprotective Effects of Estrogen
12:00 Estrogen’s Benefits in Men
16:15 How to Track Your Hormones
17:20 Testosterone Decline with Age
21:20 What’s Considered Low Testosterone
25:17 What Age to Start TRT
27:2
#434 Longevity Doctor Reveals How Genetics Affect Your Longevity
Get Bon Charge infrared sauna blanket 15% off: https://boncharge.com/pages/siimland
Timestamps:
00:30 What Is Precision Medicine
05:15 N=1 vs Fundamentals
12:10 The Longevity Equation
16:12 Bon Charge Sponsorship
17:02 How Precision Medicine Works
22:40 Can You Excrete Microplastics
28:55 How Frequently Should You Test Things
31:20 Stem cells
37:25 Cancer risk
46:40 Stem cells f
#433 SUPERPODCAST of Protocols for Diet, Exercise, Sleep, and Supplements
Timestamps:
00:00 Intro
00:40 My Evidence-Based Nutrition
17:20 Gil Carvalho on Understanding Health Information
01:01:28 Michael Lustgarten on Nutrition and Bloodmarkers
01:43:38 My Evidence-Based Workout Plan
01:59:25 Dave Pascoe Exercise Routine
02:13:50 My Evidence-Based Sleep Routine
02:26:20 My Evidence-Based Morning Routine
02:38:20 Top Evidence-Based Longevity Supplements
02:45:00 Dr Bill
#432 Top Foods and Supplements for Brain Health, Top 10 Health Items, and More - Q&A
Bon Charge holiday sale for 25% off: https://boncharge.com/pages/siimland
Timestamps:
00:00 Top Foods and Supplements for Brain Health
07:07 Best and Worst Longevity Advice I've Received
12:45 Bon Charge Red Light Therapy Sponsorship
13:36 Top 3 Spices
16:12 How I Can Eat 3500 Calories When Doing Intermittent Fasting
19:23 Top 10 Health Purchases/Item
31:38 Daily Melatonin Dose
32:23
#431 The Second Most Important Muscle In Your Body and How to Train It - Marc Hamilton PhD
Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland
Timestamps:
00:00 Intro
01:20 Marc Hamilton’s Soleus Study
08:45 Why Muscles Don’t Burn That Many Calories
13:13 Bon Charge Sponsorship
14:03 What Is the Soleus Muscle
22:08 Soleus Pushup Tutorial
31:08 Why Just Exercise Isn’t the Solution
44:20 How Long to Do the Soleus Pushup
57:45 Learn More A
#430 The Longevity Leap, Fitness, Nutrition, and Bloodwork w/ Dr Michael Lustgarten
YouTube video on Michael's channel: https://www.youtube.com/watch?v=qIloJSMZdAA&t=20s&pp=ygUUc2lpbSBsYW5kIGx1c3RnYXJ0ZW4%3D
#429 BOOST Your Testosterone NATURALLY with These Proven Methods!
Timestamps:
00:00 Intro
00:10 How Lucas got into testosterone optimization
03:30 Why are testosterone levels declining
07:15 The most powerful androgen DHT
09:30 Fundamentals to increase testosterone naturally
12:05 Compound lifts vs machines
15:10 Cortisol and testosterone
19:00 Optimal body fat for testosterone
20:30 Cholesterol and testosterone
23:00 Vitamin D and testosteron
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