Docs Who Lift

Retatrutide & Beyond: Eli Lilly Exec on Next-Gen GLP-1s Oct 7, 2026 00:58:13 Docs Who Lift finally got a big pharma exec on the show. Dr. Ken Custer is President of Lilly's Cardiometabolic Health, and he came straight from the EASD conference in Milan with fresh data on what's coming after tirzepatide.If you've been waiting on retatrutide, this is the episode. Spencer and Karl get Custer to walk through the new phase 3 results and the tirzepatide plus eluralintide combinat

Food Noise Is Real, and Now We Can Measure It Sep 22, 2026 00:49:28 Dr. David Allison and Dr. Emily Dhurandhar join Dr. Spencer Nadolsky and Dr. Karl Nadolsky to break down their new research on food noise. Patients on GLP-1s kept describing the same thing: the constant background chatter about food finally went quiet. Allison and Dhurandhar convened an expert panel of physicians, psychologists, statisticians, and eating disorder specialists to define it properly

Does Metabolically Healthy Obesity Even Exist? Aug 30, 2026 00:48:28 Dr. Christian Rodriguez joins the show straight from Pennington Biomedical, where he works alongside obesity research legends Eric Ravussin and Steve Heymsfield. He breaks down his new review on metabolically healthy obesity and why the old "zero metabolic syndrome criteria" definitions are so inconsistent. The conversation dives deep into the Lancet Commission's new obesity framework, comparing i

Is Your Obesity Genetic? Food Noise and Bardet-Biedl Syndrome Explained Aug 3, 2026 00:39:46 Could your weight gain and non-stop thoughts about food actually come from a rare condition you were born with? In this episode of the Docs Who Lift podcast, Dr. Spencer Nadolsky and Dr. Karl Nadolsky chat with weight expert Dr. Jesse Richards about Bardet-Biedl Syndrome (BBS). This rare condition tricks your brain into thinking your body is starving, even when you have plenty of body fat stored u

PCOS Renamed to PMOS? Here's Why and What Changes for You Jul 7, 2026 00:36:52 In this episode they cover why the name polycystic ovarian syndrome has been misleading from the start given that you do not need polycystic ovaries to have the condition and you can have polycystic ovaries without having the condition at all, what the Rotterdam criteria actually are and why having two of three features including irregular periods, elevated androgens, and polycystic ovarian morpho

Are Peptides the New Snake Oil? What the Actual Science Says With Barbell Medicine Jun 17, 2026 00:57:24 Dr. Spencer Nadolsky and Karl bring on Dr. Austin Baraki and Dr. Jordan Feigenbaum from the Barbell Medicine crew for a conversation that cuts through one of the most hyped and least understood topics in the health and fitness space right now: the research peptides that millions of people are injecting into themselves based on anecdotes, social media marketing, and the logic that short chain amino

Retatrutide Phase 3 Results: What the Data Actually Means Jun 8, 2026 00:45:03 Dr. Spencer and Karl Nadolsky sit down with David W, a nurse practitioner and one of the actual patients enrolled in the Triumph 1 retatrutide phase 3 trial, to break down the data that was just presented at the American Diabetes Association conference and explain why everyone in obesity medicine is paying very close attention. In this episode they cover what retatrutide actually is and why adding

GLP-1 Maintenance: What Happens When You Lower Your Dose, Switch Medications, or Stop Entirely May 25, 2026 00:39:46 Dr. Spencer Nadolsky and Karl break down two brand new randomized controlled trials that put hard numbers on a question they have been navigating clinically for years: what actually happens to patients on GLP-1 medicines when they try to lower their dose, switch to a cheaper option, or come off entirely. In this episode they cover why obesity biology actively fights back against weight loss throug

Are GLP-1 Medicines Shredding Your Bones? Here Is What the Actual Evidence Says With Dr. Susan Brian May 18, 2026 00:31:42 Dr. Spencer Nadolsky and Karl sit down with Dr. Susan Brian, a Yale-trained endocrinologist, certified menopause provider, and medical director of a clinic with seven endocrinologists who runs an active bone fragility fracture clinic, to answer the question that has been flooding social media since a viral abstract with two fake bones on a surgical table convinced people their skeletons are quietl

Heavy Metal Toxicity: Separating Real Risks From Influencer Scams | Dr. Eryn Russo May 5, 2026 00:52:36 Dr. Spencer Nadolsky and Karl sit down with Dr. Eryn Russo, a board-certified occupational and environmental medicine physician with nearly 20 years of experience working at Hill Air Force Base, where she deals with real toxic metal exposures every single day. She is one of less than one percent of all board-certified physicians practicing in this specialty, which makes her exactly the person you

GLP-1 Genetics: Predicting Weight Loss and Side Effects With 23andMe's Dr. Adam Auton Apr 21, 2026 00:24:36 Dr. Spencer Nadolsky and Karl sit down with Dr. Adam Auton, geneticist at 23andMe, to break down a brand new paper using data from over 27,000 people that identified specific genetic variants linked to how well GLP-1 medications work and how likely someone is to experience side effects. 23andMe has over 11 million people in their research database and used voluntary survey data on medication use,

Do GLP-1 Medicines Actually Cause Muscle Loss? New Research With Dr. Henning Langer Apr 14, 2026 00:36:25 5:37 PM Dr. Spencer Nadolsky and Karl sit down with Dr. Henning Langer, PhD researcher at the Charité in Berlin and founder of his own muscle metabolism lab, to break down his newly published paper combining rodent and human data to look directly at what GLP-1 medicines actually do to skeletal muscle beyond what a DEXA scan can tell you. Dr. Langer spent time at Boehringer Ingelheim spec

How Often Should You Really Lift Weights? Feat. Dr. Stuart Phillips Apr 2, 2026 00:51:56 Dr. Spencer Nadolsky and Dr. Karl Nadolsky sit down with Dr. Stuart Phillips, senior author on the newly updated American College of Sports Medicine position stand on resistance training, to break down what 137 systematic reviews and over 30,000 participants actually tell us about building muscle, getting stronger, and improving function across the lifespan. The last version of these guidelines wa

Bimagrumab and Semaglutide: The BELIEVE Trial Results With Dr. Steven Heymsfield Mar 23, 2026 00:38:42 Dr. Spencer Nadolsky, Dr. Karl, and chief science officer Dr. Grant Tinsley sit down with Dr. Steven Heymsfield, physician at the Pennington Biomedical Research Center and lead author on the BELIEVE trial, to break down what happens when you combine bimagrumab with semaglutide and why over 90 percent of weight lost in the combination group was pure fat. Dr. Heymsfield has published over 600 peer r

Menopause, Muscle, and the Myths | Dr. Alyssa Olenick Mar 13, 2026 00:49:39 Dr. Spencer and Karl Nadolsky bring on Dr. Alyssa Olenick, exercise physiologist and postdoctoral researcher in menopause and metabolism, to cut through the noise on one of the most misrepresented topics in women's health. Dr. Olenick holds a PhD in exercise physiology, completed postdoctoral training focused on menopause and body composition, and is the founder of the Liss Method, a hybrid traini

The Truth About Creatine (Doctors Discuss) Mar 6, 2026 00:35:06 Takeaways: Creatine is a naturally occurring compound that helps regenerate ATP, the energy currency of the cell. Supplementing with creatine can enhance performance in high-intensity exercise but may not be beneficial for endurance activities. The majority of creatine is stored in muscle, and supplementation can help fill those stores for better energy availability. Creatine monohydrate is the mo

Top Sleep Doctor: Stop Taking Melatonin Like This Feb 23, 2026 00:48:33 Takeaways:The 11-Minute Rule: Why blue light isn't the villain you think it is. The Melatonin Mistake: Why "less is more" (and the exact dosage for success). Trackers vs. Reality: When to throw away your Apple Watch or Oura Ring. The Bedrock Principle: Why sleep is the lead domino for fat loss and metabolic health. Sex & Sleep: The surprising biological difference in how men and women recover. Tap

GLP-1s and Fertility What to Know Before Trying to Conceive Feb 12, 2026 00:54:19 Get The Lucky Egg Book HereTakeaways:Dr. Lucky Sekhon is a reproductive endocrinologist and author of 'The Lucky Egg'.The pathway to reproductive endocrinology involves extensive training in OB-GYN and specialized fellowship.Social media became a tool for Dr. Sekhon to combat misinformation during the pandemic.Common myths in fertility include the idea that one can reverse the biological clock.Und

Reclaiming Excellence: A Conversation with Brad Stulberg Jan 30, 2026 00:45:13 TakeawaysExcellence is not a standard but a process of becoming.Involved engagement means caring deeply about what you do.The pursuit of excellence shapes you into a better person.Consistency is key to achieving long-term goals.It's important to align your pursuits with your values.Youth sports can be beneficial but also harmful if not approached correctly.Weight loss should shift from a focus on

Oral GLP-1 (Wegovy) Is Here: Dosing, Switching, and What to Expect Jan 20, 2026 00:25:23 Key Episode TakeawaysOral Wegovy is real, but it’s not “just a pill version of the shot.” Absorption rules, dosing schedules, and patient selection matter a lot more than most headlines suggest.Switching from injections to oral GLP-1s requires a plan. The transition isn’t one-size-fits-all, and dose timing, GI tolerance, and expectations need to be managed carefully.Weight regain after stopping GL

Breaking Down the New Food Pyramid (Great or Confusing) Jan 12, 2026 00:29:55 Takeaways:Dietary guidelines have evolved since the 1980s.The food pyramid was introduced in 1992 and has influenced public perception.New dietary guidelines emphasize healthy fats but retain some old recommendations.There are contradictions in the new guidelines regarding saturated fat and protein intake.The definition of processed foods remains vague and controversial.The guidelines are intended

Cortisol Myths vs Reality: What Your Adrenals Actually Do Jan 7, 2026 01:03:28 Takeaways:Cortisol is essential for various bodily functions, especially during stress.Adrenal glands have a circadian rhythm that affects cortisol production.Cushing's syndrome can result from excess cortisol and has specific symptoms.Diagnosis of adrenal disorders requires careful testing and consideration of symptoms.Mild autonomous cortisol secretion can complicate diabetes management.The Cata

GLP-1 Side Effects Deep Dive: Slimmer's Paralysis, Bladder Spasms, & Reactive Hypoglycemia. Dec 5, 2025 00:31:54 Takeaways:Slimmer's Paralysis is a recognized condition.Ethical boundaries are crucial in patient relationships.Medical professionals must maintain professionalism at all times.Humor can sometimes arise in serious discussions.Patient stories should always be handled with care.The importance of clear communication in medical settings.Understanding patient experiences is vital for effective care.Eth

GLP-1s and Breast Milk: What the New Research Actually Found Nov 19, 2025 00:34:08 Takeaways:Drug transfer during lactation is complex and challenging.Semaglutide was not detected in women taking any dose.Low amounts of tears epitide were found in milk.Tissue damage can affect drug absorption.Mastitis and engorgement complicate the lactation process.Injections are necessary for effective drug delivery.The analogy of an elephant illustrates the difficulty of drug transfer.Detecti

How to Build Healthy Routines That Actually Stick Nov 12, 2025 00:35:23 Takeaways:Behavior change is a complex process that requires understanding motivation and discipline.Motivation is not just a feeling; it's a psychological skill that can be developed.Many common phrases about behavior change are misleading and oversimplified.Exercise should be viewed as a choice rather than a habit that becomes automatic.Self-efficacy is crucial for successful behavior change and

The Truth About Testosterone Therapy in Women (with Dr. Susan Davis) Nov 3, 2025 01:00:56 Testosterone therapy can improve libido in postmenopausal women.Sexual dysfunction in women is complex and multifactorial.Low sexual desire is only considered a disorder if it causes distress.Psychosocial factors play a significant role in sexual health.Testosterone levels do not change significantly at menopause.The placebo effect can significantly influence treatment outcomes.Individualized care

From Injections to Pills: Breaking Down the New Oral GLP-1 Data Oct 23, 2025 00:32:01 Show Notes:In this episode of Docs Who Lift, the Nadolsky brothers welcome back Dr. Sean Wharton, clinical trialist and one of the leading researchers behind the next generation of oral GLP-1 medications. Together, they break down:The OASIS-4 trial results on 25mg oral semaglutide and how it stacks up to injectable WegovyHow orforglipron, Eli Lilly’s new small-molecule GLP-1, differs from peptide-

De-Emphasizing BMI, Prioritizing Health: What’s New in the ACE Obesity Guidelines Oct 13, 2025 00:48:03 In this episode of Docs Who Lift, the Nadolsky brothers dive deep into the newly released American Association of Clinical Endocrinology (ACE) Algorithm for Obesity Care led by Dr. Karl himself. They explore:Why ACE moved away from a BMI-only approach to a person-centered, complication-centric modelThe new staging framework (ABCD) that helps individualize treatment intensityHow to interpret “clini

Debunking The Myths of Metabolism and Weight Loss Sep 25, 2025 00:57:56 TakeawaysThe book aims to dispel myths surrounding the Biggest Loser study.Miscommunication in media has led to public confusion about metabolism.Metabolic adaptation is a response to weight loss, not a determinant of it.Cultural factors significantly influence eating habits and food choices.The food environment plays a crucial role in dietary behaviors.Bipartisan support is necessary for effectiv

Menopause Medicine Meets Obesity Care: Doctors React Sep 1, 2025 00:39:26 Takeaways Menopausal women often prioritize weight gain concerns over other symptoms.The study observed an association between hormone therapy and weight loss with GLP-1 medications.Retrospective studies have limitations but can provide valuable insights.Future research should focus on randomized controlled trials to confirm findings.The relationship between estrogen and GLP-1 signaling needs furt

Women’s Fitness Needs Debate: Dr. Stacy Sims vs. Dr. Lauren Colenso-Semple Aug 29, 2025 01:07:13 We covered:Fasted trainingProtein timingand many more fitness topics!Hear Dr. Lauren Colenso-Semple and Dr. Stacy Sims discuss outcomes versus mechanisms and much moreTap Here for Dr Stacy Sims ReferencesTap Here for Dr. Colenso-Semples ReferencesDr. LCS InstagramDr. SS Instagram Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal

Do You Really Lose Muscle on Semaglutide or Tirzepatide? Aug 22, 2025 00:33:50 TakeawaysThe podcast features Dr. Grant Tinsley, a body composition expert.The discussion revolves around a case series on body composition effects.GLP-1 receptor agonists are a focus of the research.The importance of resistance training in weight loss is emphasized.Patient case studies provide insights into individual experiences.The first patient lost a significant amount of fat mass while prese

Predatory Lab Testing: What They’re Not Telling You Aug 16, 2025 00:49:50 TakeawaysDirect-to-consumer lab testing is on the rise, with significant marketing efforts behind it.Many patients feel brushed off by traditional healthcare providers, leading them to seek alternative testing options.Communication between patients and healthcare providers is often inadequate, contributing to misunderstandings about health.Over-testing can lead to unnecessary anxiety and misinterp

CVS Pulled the Plug on Zepbound?! Aug 8, 2025 00:20:12 In this episode of the Dr. Lift podcast, hosts Dr. Spencer Nadolsky and Dr. Karl discuss the recent changes in obesity medication coverage, particularly focusing on the CVS Caremark decision to drop ZEPBound from their formulary in favor of Wegovi. They explore the implications of this decision for patients and providers, the role of pharmacy benefit managers (PBMs) in healthcare, and the ongoing

More Than Weight Loss? GLP-1s and Cardiovascular Risk Aug 3, 2025 00:11:16 In this episode of the Dr. Lift podcast, hosts Dr. Spencer Nadolsky and Dr. Karl discuss the Surpass CVOT trial, which evaluates the cardiovascular outcomes of Monjaro compared to Dulaglutide (Trulicity). They delve into the significance of the trial, the implications of the results, and the potential benefits of Monjaro for patients with type 2 diabetes and cardiovascular risks. The conversation

Semaglutide vs. Tirzepatide: Are We Closing the Gap? Jul 24, 2025 00:41:34 How the STEP-UP trial came to life, and what made the 7.2mg dose possibleWhat the data actually says about weight loss and side effects at higher dosesWhy trial design, pharmacokinetics, and estimands matter more than you thinkWhat’s coming next in obesity meds: duals, triples, and even antagonistsThe real talk on intermittent fasting, access issues, and preaching vs. scienceSign up for Dr. Spenc

Clinical vs Anthropometric Obesity Jul 2, 2025 00:31:36 TakeawaysThe study examines the overlap between clinical and anthropometric obesity.Anthropometric measures include waist circumference, waist-to-hip ratio, and BMI.Challenges exist in applying the Lancet Commission's definitions in clinical practice.Metabolically healthy obesity is a debated topic in obesity research.The study highlights the importance of data from the All of Us Research Program.

GLP-1 meds and macular degeneration Jun 23, 2025 00:33:33 Learn what age-related macular degeneration (AMD) isWhat causes AMDThe types of AMDThe update on NAION - listen to last year's podcast all about itWhy we aren't too concernedClick here to join Dr. Spencer's online clinic VineyardClick to read the JAMA AMD articleClick to read the Ophthalmology journal AMD article Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about o

Menopause, MHT, and GLP-1 medicines Jun 12, 2025 00:27:48 Menopausal hormonal therapy should not be a blanket recommendation for everyone going through menopauseWeight management in women is influenced by hormonal changes throughout life stages.Retrospective analyses can provide insights but have limitations.The wellness industry often oversimplifies complex medical issues.Hormonal replacement therapy may have subtle benefits for weight management.Confou

The Science of Myostatin inhibitors, GLP-1 meds and Muscle Mass Jun 6, 2025 00:28:28 Dr. Grant Tinsley joins the discussion as the body composition expert.Myostatin is a key regulator of muscle growth.Wendy Whippete the most jacked muscled up dogThe concern of GLP-1 receptor agonists and muscle mass loss.Overview of Courage trial looking at semaglutide and trevogrumab and lean mass lossUpcoming Believe trial coming out (bimagrumab and semaglutide)Exercise remains crucial for muscl

Current State of Nutrition Research and MAHA May 29, 2025 00:56:22 Takeaways:The MAHA report aims to address public health issues but lacks actionable policies.Historical context is crucial for understanding current dietary guidelines.Funding for nutrition research has been inadequate, impacting the quality of data.Public perception of nutrition often outpaces scientific evidence.The evolution of dietary guidelines reflects political and social influences.There i

Joy Prescriptions May 13, 2025 00:46:48 Click to read Joy PrescriptionsDrs. Karl and Spencer talk to Dr. Tiffany Moon all about Joy Prescriptions. Learn how to stop chasing perfection and embrace connection. 00:00Introduction to Dr. Tiffany Moon02:02Journey to Reality TV: The Real Housewives of Dallas05:58Life After Reality TV: Finding Joy and Purpose09:59The Joy Prescription: A New Approach to Life17:01Work-Life Integration: Balancing

Zepbound versus Wegovy May 12, 2025 00:20:57 Tirzepatide is more effective for weight loss than semaglutide.Cost-effectiveness is crucial in prescribing weight loss medications.Patients with severe obesity should receive more expensive medications for better outcomes.Both medications show significant benefits for obesity-related conditions.Long-term studies indicate sustained weight loss with both drugs.Gender differences affect weight loss

Semaglutide for metabolic dysfunction associated steatotic liver disease (MASH). May 2, 2025 00:22:20 TakeawaysMASH is a significant obesity-related complication.Semaglutide shows promise in treating MASH.Weight loss is crucial for improving liver health.Bariatric surgery remains the most effective treatment.The Essence trial indicates a 63% resolution of NASH.New medications are being developed for obesity treatment.Early intervention is key to preventing severe liver damage.Accessibility of medi

Top 5 Women's Fitness Myths Apr 25, 2025 00:36:48 Drs. Karl and Spencer chat with return guest Dr. Lauren Semple about creatine, protein, cortisol, fasting exercise, and training in women.Follow Dr. Lauren's instagramJoin Dr. Spencer's online clinic Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

GLP-1 and metabolism and depression Apr 11, 2025 00:25:00 Drs. Karl and Spencer discuss a new study looking at tirzepatide and metabolic rate. They also discuss a patient case of tirzepatide induced anhedonia.Here is the tirzepatide studyIf interested in joining Dr. Spencer's clinic Vineyard - Click Here Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Do GLP-1 meds cause more fat cells? Mar 19, 2025 00:25:52 Drs. Karl and Spencer discuss the claim that GLP-1 meds cause more fat cells.Learn about if and how GLP-1 meds increase fat cells and what that means along with other claims about these medicine.Join Dr. Spencer's online clinic that specializes in GLP-1 medicines Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertis

Future of medicine - Direct Care Mar 11, 2025 00:23:15 Drs. Karl and Spencer talk to Dr. Kenneth Qiu all about direct medical care - the future of medicine.Learn about how bypassing insurance and creating a relationship directly with a doctor can improve your health and save money in the long run.Follow Dr. Qiu on Linked inSee Dr. Spencer's direct care model with Vineyard Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information ab

Tirzepatide and Muscle Loss with Dr. Grant Tinsley Feb 28, 2025 00:27:44 Drs. Karl and Spencer discuss with Dr. Grant Tinsley all about the new analysis of how much "lean mass" is lost with tirzepatide, the most powerful medicine available for weight loss.Learn:The difference between fat free mass and lean mass and lean soft tissue and muscle.If GLP-1 medicines cause muscle loss specificallyHow to minimize muscle loss when taking these medicinesOur new study together.C

The Super Bowl Hims and Hers Ad Feb 17, 2025 00:25:05 Drs. Karl and Spencer discuss how bad the Hims and Hers ad was.From an outside perspective, the ad may have seemed good.But when you dig deeper, it was actually really bad.Listen to learn.Join Dr. Spencer's new online clinic - Vineyard. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

NAD and NMN with Dr. Charles Brenner Feb 12, 2025 00:38:56 Drs. Karl and Spencer chat with NMN and NAD expert Dr. Charles Brenner all about these supposed longevity supplements.Learn about NAD metabolismWhether it's worth supplementing or not with NAD or NMNFollow Dr. Brenner on Twitter Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The 60 Minutes Obesity Doctor - Dr. Fatima Cody Stanford Jan 28, 2025 00:45:33 Drs. Karl and Spencer chat with Dr. Fatima Cody Stanford all about obesity, genetics, and her appearance on 60 minutes.Does Dr. Sanford believe lifestyle doesn't matter for obesity?Find out by listening!Watch Dr. Stanford's 60 minute clip Join Dr. Spencer's Obesity Clinic Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for

New Obesity Definition and Higher Wegovy Dose Jan 20, 2025 00:29:12 Drs. Karl and Spencer chat about the new Lancet Commission's report on Clinical Obesity along with the new study on high dosed Wegovy. Learn:How 7.2 mg of Wegovy (semaglutide) compares to 2.4 mgWhat the proposed definitions of clinical and preclinical obesity areClick here to join Dr. Spencer's new online clinic Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about ou

The Ozempic Revolution - with Dr. Sowa Jan 10, 2025 00:31:15 Drs. Karl and Spencer chat with Dr. Sowa about her book The Ozempic Revolution.Learn:Why she wrote the book.The top 3 things to know when starting a GLP-1 medicine.Also hear the top criticism from Drs. Karl and Spencer. You will laugh.Click here to get the bookIf you're on a GLP-1 currently and want to switch to Dr. Spencer's new clinic, Click Here Hosted by Simplecast, an AdsWizz company. See pcm

Microdosing GLP-1 and Cagrisema headlines Dec 23, 2024 00:40:20 Drs. Karl and Spencer discuss the concept of "microdosing" GLP-1 receptor agonists along with talk about the new top line results from REDEFINE which studied the new drug CagriSema. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Changing your workouts based on your menstrual cycle Dec 18, 2024 00:30:07 Drs. Karl and Spencer chat with Dr. Lauren Colenso-Semple all about how the menstrual cycle and how it should affect your workout programming. Should you change your workouts around your menstrual cycle? Find out by listening! Check out her instagramRead her paper on exercise and menstrual cyclesRead her paper on protein synthesis throughout the menstrual cycle Hosted by Simplecast, an AdsWizz com

Zepbound vs Wegovy trial and compounded GLP-1s Dec 9, 2024 00:44:15 Drs. Karl and Spencer discuss the topline results from Surmount 5 which put Zepbound (tirzepatide) against Wegovy (semaglutide) for weight loss. They also discuss some news around compounded GLP-1s.Learn:Weight loss and glycemic differences between tirzepatide and semaglutideWhat the FDA is thinking for compounded GLP-1sIf you're not on Dr. Spencer's virtual clinic waitlist, click here Hosted by S

Types of Diabetes, CGMs, and More Nov 25, 2024 01:06:07 Drs. Karl and Spencer chat with Dr. Shivani Misra, a metabolic specialist physician researcher from the UK, all about the various forms of diabetes mellitus.Learn:The types of diabetes mellitusThe monogenic forms (some what refer to as MODY)The differences within type 2 diabetesWhether CGMs (continuous glucose monitors) are usefulIf low carb could help someFollow Dr. Misra on X/Twitter Hosted by

A new way of delivering healthcare - Direct Primary Care Nov 20, 2024 01:08:59 Drs. Karl and Spencer chat with AtlasMD - Dr. Josh Umbehr all about making healthcare cheaper using direct primary care.Learn:How cheap labs and and meds should beHow cutting out the middlemen can help healthcare and decrease costsFind AtlasMD here Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

1st longer term tirzepatide study (3 years) Nov 14, 2024 00:44:41 Drs. Karl and Spencer discuss the brand new 3 year study of tirzepatide in those with prediabetes along with a discussion on semaglutide treating osteoarthritis.Learn:If people lose weight and keep it off with tirzepatideHow many people regain weight after stopping the medicineLong-term side effectsIf semaglutide helps with osteoarthritisClick here to read the tirzepatide studyClick here to read t

Making America Healthy Again - Joe Rogan Podcast Review Nov 1, 2024 00:53:12 Drs. Karl and Spencer invite Dr. Andrea Love back to the podcast to discuss a recent Joe Rogan podcast with Calley and Casey Means along with the concept of Make America Healthy Again and RFK jr.Learn:What the docs agree with.What they don't agree with.Is raw milk okay?Are cancer rates rising?and moreFollow Dr. Andrea here https://www.instagram.com/dr.andrealove Hosted by Simplecast, an AdsWizz co

Cortisol 101 Oct 15, 2024 00:31:06 Drs. Karl and Spencer discuss all things cortisol and poke fun at the influencers who try to fear monger exercise due to cortisol increases.Learn:What is cortisol and what does it do?Is cortisol bad?Should you worry about cortisol increases with exercise?Should you take supplements to lower cortisol?and more Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our c

New Healthcare Service Oct 2, 2024 00:22:05 Drs. Karl and Spencer discuss their ideal healthcare delivery system.Learn:Spencer's journey building and selling Sequence and what he wants to do next.How Dr. Karl believes healthcare should be and what he's doing next.Click here to get on Dr. Spencer's waitlist Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for adverti

Obesity medicine updates and Kardashian supplements Sep 16, 2024 00:40:13 Drs. Karl and Spencer discuss BS supplements claiming to be like Ozempic along with discuss some new obesity drugs coming down the pipeline that were announced in phase 1 and 2 trials.Are there any supplements that can mimic Ozempic?What is amylin and how does it help with weight and sugars?What is this new oral drug "amycretin" in phase 1 trials?and more Hosted by Simplecast, an AdsWizz company.

Menopause 101 Sep 9, 2024 01:15:58 Drs. Karl and Spencer chat with Dr. Jen Gunter all about menopause.Learn:How it's diagnosed.When and when not to treat.The various treatment.If it is indicated for cardiovascular disease prevention or body composition.Whether or not you should get labs.See more at Dr. Gunter's website Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of per

Olympic controversies and GLP-1 for Alzheimer's and Heart Failure Aug 7, 2024 00:27:26 Drs. Karl and Spencer talk about the top line results from study showing liraglutide may have some benefit in Alzheimer's along with top line results from the Summit trial showing heart failure benefits with tirzepatide.They also discuss the women's boxing controversy and BMI in athletes. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of

New Vitamin D Guidelines Jul 30, 2024 00:30:35 Drs. Karl and Spencer chat with return guest and bone expert endocrinologist Dr. Rachel Pessah-Pollack all about the new Vitamin D guidelines.Should healthy people even check a vitamin D level?Should they supplement with vitamin D?What people should check or supplement?Click here for the new guidelines Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collect

Semaglutide and Blindness Jul 8, 2024 00:51:02 Does semaglutide cause blindness?What is NAION (nonarteritic anterio ischemic optic neuropathy)?What about worsening of diabetic retinopathy with semaglutide?What can you do to minimize the risk of NAION and retinopathy?Get the full study hereRead Dr. Brugger's blog Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for adver

Tirzepatide for Obstructive Sleep Apnea Jun 26, 2024 00:19:37 Tirzepatide may be a good option if you have obesity and obstructive sleep apnea.Click here to read the study Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Stomach Ablation for Weight Loss Jun 21, 2024 00:34:18 Click here to read about the gastric ablation and trial.Click here to see Dr. McGowan's clinic Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

FLOW trial and GLP-1 cost rant Jun 4, 2024 00:45:30 Drs. Karl and Spencer discuss the recent FLOW trial where semaglutide was found to be kidney protective. They also go off about the costs of these medicines and what to do (including compounding considerations). Click here to see the study Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

South Park - The End of Obesity May 28, 2024 00:20:30 Drs. Karl and Spencer discuss the most recent South Park episode where GLP-1 medicines are discussed along with the dysfunctions of our healthcare system among other issues. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Fallacies of Functional Medicine May 16, 2024 00:26:59 Drs. Karl and Spencer discuss the fallacies of functional medicine. You'll learn what functional medicine is and whether you should seek it out. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Another response to Jillian Michaels and Bill Maher Apr 30, 2024 00:20:24 Drs. Karl and Spencer respond to Jillian Michaels on the Bill Maher show Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Bariatric surgery through the mouth? Endoscopy gastroplasty 101 Apr 24, 2024 00:38:36 Drs. Karl and Spencer discuss with gastroenterologist Dr. McGowan all about endoscopic gastroplasty. See recent study on cost effectiveness of endoscopic gastroplasty vs semaglutide Check out his program Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

GLP-1 meds and Parkinson's and Heart Failure Apr 12, 2024 00:24:11 Drs. Karl and Spencer discuss the new studies about GLP-1 medicines and Parkinson's and heart failure along with how these meds are not just weight loss drugs but health promoting medicines. Click here to see the Parkinson's study Click here to see the heart failure study Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data fo

Lipedema Patient Journey Mar 26, 2024 00:25:45 Drs. Karl and Spencer chat with Kasey Potts all about her journey with lipedema. Learn more about how this condition is diagnosed and treated. Check out her instagram Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

All about Lipedema - with Dr. Amron Mar 13, 2024 00:51:34 Drs. Karl and Spencer chat with Dr. Amron all about lipedema. He is a specialized surgeon who treats lipedema daily. Learn about diagnosing and treating this condition that is commonly mistaken with obesity. Check his sites https://www.dramronconsultations.com/ https://www.advancedlipedematreatment.com/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our colle

GLP-1 Weight Loss Maintenance from Exercise Mar 5, 2024 00:21:03 Drs. Karl and Spencer discuss a new study showcasing the importance of exercise during and after GLP-1 medicine use. Click here to see the original study Click here to see the extension study Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Bustin' Hyman Myths - GLP-1 edition Feb 27, 2024 00:28:52 Drs. Karl and Spencer discuss a recent Mark Hyman podcast where he perpetuated some myths about obesity and GLP-1 receptor agonist medicines. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Episodes

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